Prof. dr. A.H.C. van Kampen
| Title | Prof. dr. |
|
| Initials | A.H.C. | |
| Surname | van Kampen | |
| First name | Antoine | |
| E-mail address | A.H.C. van Kampen | |
| Position | ||
| Main activities | Research | |
| Specialisation |
A.H.C. van Kampen is one of the AMC Principal Investigators.
Focus of research
The Bioinformatics Laboratory aims to develop novel strategies, methods, and expertise for the extraction of biomedical knowledge from complex data. This data generally comprises omics measurements (and complementary clinical data) but also medical images stemming from e.g., fMRI. Our research advances the organization, integration, analysis, and interpretation of biomedical data and, moreover, results in Grid infrastructures that provide significant computing power and approaches to manage data in distributed environments. These infrastructures are applied to address complex biomedical questions.
Most of the (research) projects are defined and carried out in tight collaboration with (AMC) laboratories and (pre)clinical research groups. The main research lines are Systems Genomics, e-Bioscience, and Semantic Biosystems. In addition, the lab participates in many collaborations focused on the analysis and interpretation of omics data. These collaborations include many DNA microarray projects and some proteomics projects. Moreover, the analysis of next generation sequence data constitutes an increasing part of our work. The lab also has large experience in the use and integration of public biological databases. e-Science is embraced for selected projects to facilitate projects that are carried out in distributed environments or which require large compute power. Most of the (research) activities provide a strong basis for systems biology.
The lab contributes to education and training programmes of Medical Informatics (AMC), the International class of Medical Informatics, AMC Graduate School for Medical Sciences, Biomedical Sciences (University of Amsterdam) and Computational Sciences (University of Amsterdam) and the NBIC PhD School.
| AMC themes | Cardiovascular Diseases; Gastro-Intestinal Diseases; Infection & Immunity; Metabolic Disorders; Neurological & Psychiatric Disorders; Oncology. |
| Departments | Clinical Epidemiology, Biostatistics and Bioinformatics (KEBB). |
Key publications
- Klarenbeek PL, Tak PP, van Schaik BDC, Zwinderman AH, Jakobs ME, Zhang Z, van Kampen AHC, van Lier RAW, Baas F, de Vries N, Human T Cell Memory Consists Mainly Of Unexpanded Clones. IMMUNOLOGY LETTERS , 2010 [aheadofprint]
- van Hooff SR, Koster J, Hulsen T, van Schaik BDC, Roos M, van Batenburg MF, Versteeg R, van Kampen AHC, The Construction of Genome-Based Transcriptional Units. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY 13 (2), 2009, p.105-114
- Willemsen AM, Jansen GA, Komen JC, van Hooff S, Waterham HR, Brites PMT, Wanders RJA, van Kampen AHC, Organization and integration of biomedical knowledge with concept maps for key peroxisomal pathways. BIOINFORMATICS 24 (16), 2008, p.I21-I27
- van Passel MWJ, Bart A, Thygesen HH, Luyf ACM, van Kampen AHC, van der Ende A, An acquisition account of genomic islands based on genome signature comparisons. BMC GENOMICS 6, 2005, p.163-
- van Passel MWJ, Luyf ACM, van Kampen AHC, Bart A, van der Ende A, Deltarho-web, an online tool to assess composition similarity of individual nucleic acid sequences. BIOINFORMATICS 21 (13), 2005, p.3053-3055
Research programmes
Prof. dr. A.H.C. van Kampen - Medical Bioinformatics and e-BioscienceThe Bioinformatics Laboratory is engaged in different types of research and support projects The main research efforts comprise (a) Systems Bioinformatics, (b) e-Bioscience and (c) sequence analysis. See also www.bioinformaticslaboratory.nl
to be completed
| Faculty | Postdocs | PhD students | Others |
|---|---|---|---|
|
Prof. dr.
A.H.C. van Kampen
(Leader)
Dr. ir. P.D. Moerland Dr. S.D. Olabarriaga B.D.C. van Schaik Drs. A.M. Willemsen |
Dr.
C.
Byrman
Dr. G.A. Jansen Dr. Y. Mohammed |
U.
Nandal
MSc
Drs. M.D. Stobbe |
A.C.M.
Luyf
M.A. Santcroos S. Shahand MEng |
Other research related activities
- Member of Management Team, Netherlands Bioinformatics Centre
- Contribution to training of professionals, NBIC PhD school
- Membership of advisory board / Consultant, Other
Current research funding
- Europese Unie
- Netherlands Genomics Initiative
- Stichting Nationale Computerfaciliteiten
- Stichting NBIC
Last updated on: 01/07/2010
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