Researchers

  • Female

Dr. E. Velthorst MSc

Position: Postdoc
Main activities: Research
Specialisation: Early Psychosis
foto
Focus of research:

The focus of my research over the past year has been the population at Ultra High Risk for developing a first psychosis.

At the moment, I am involved in the European Network of national schizophrenia networks studying Gene-Environment interartions (EU-GEI). 

In this large-scale collaboration, the aim is to identify, over a 5-year period, the interactive genetic, clinical and environmental determinants, involved in the development, severity and outcome of schizophrenia.

AMC themes: Neurological & Psychiatric Disorders
Departments: Psychiatry: Adult Psychiatry
Kraan TC. Environmental risk factors in the ultra high risk stage of psychosis. S.l.: s.n.; 2017. 185p. ISBN 978-90-826049-8-6 Proefschrift Free University, Human movement sciences. (Promotor(s): van der Gaag M, de Haan L; copromotor(s): Velthorst E)
Kraan TC, Ising HK, Fokkema M, Velthorst E, van den Berg DPG, Kerkhoven M, Veling W, Smit F, Linszen DH, Nieman DH, Wunderink L, Boonstra N, Klaassen RMC, Dragt S, Rietdijk J, de Haan L, van der Gaag M, The effect of childhood adversity on 4-year outcome in individuals at ultra high risk for psychosis in the Dutch Early Detection Intervention Evaluation (EDIE-NL) Trial. PSYCHIAT RES 2017;247:55-62 [PubMed]
Kraan TC, Velthorst E, Themmen M, Valmaggia L, Kempton MJ, McGuire P, van Os J, Rutten BPF, Smit F, de Haan L, van der Gaag M, Child Maltreatment and Clinical Outcome in Individuals at Ultra-High Risk for Psychosis in the EU-GEI High Risk Study. SCHIZOPHRENIA BULL 2017;ahead of print [PubMed]
Tedja A, Velthorst E, van Tricht M, de Haan L, Preliminary validation of a clinical staging model in schizophrenia and related disorders. CLIN SCHIZOPHR RELAT PSYCHOSES 2017;ahead of print [PubMed]
van Dam DS. Untangling pathways between childhood trauma and psychosis. S.l.: s.n.; 2017. 202p. ISBN 978-94-6295-536-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): de Haan L; copromotor(s): Meijer CJ, Velthorst E)
Velthorst E, Smith L, Bello G, Austin C, Gennings C, Modabbernia A, Franke N, Frangou S, Wright R, de Haan L, Reichenberg A, Arora M, New Research Strategy for Measuring Pre- and Postnatal Metal Dysregulation in Psychotic Disorders. SCHIZOPHRENIA BULL 2017;ahead of print [PubMed]
Andric S, Maric NP, Knezevic G, Mihaljevic M, Mirjanic T, Velthorst E, van Os J, Neuroticism and facial emotion recognition in healthy adults. EARLY INTERV PSYCHIA 2016;10 (2):160-164 [PubMed]
Kraan TC, Velthorst E, de Haan L, van der Gaag M, Disentangling cause and effect in the relationship between cannabis and psychosis: are we there yet? Reply. PSYCHOL MED 2016;46 (14):3063-3064
Kraan T, Velthorst E, Koenders L, Zwaart K, Ising HK, van den Berg D, de Haan L, van der Gaag M, Cannabis use and transition to psychosis in individuals at ultra-high risk: review and meta-analysis. PSYCHOL MED 2016;46 (4):673-681 [PubMed]
Modabbernia A, Velthorst E, Gennings C, de Haan L, Austin C, Sutterland A, Mollon J, Frangou S, Wright R, Arora M, Reichenberg A, Early-life metal exposure and schizophrenia: A proof-of-concept study using novel tooth-matrix biomarkers. EUR PSYCHIAT 2016;36:1-6 [PubMed]
Velthorst E, Fett AKJ, Reichenberg A, Perlman G, van Os J, Bromet EJ, Kotov R, The 20-Year Longitudinal Trajectories of Social Functioning in Individuals With Psychotic Disorders. AM J PSYCHIAT 2016;ahead of print [PubMed]
Velthorst E, Reichenberg A, Kapara O, Goldberg S, Fromer M, Fruchter E, Ginat K, de Haan L, Davidson M, Weiser M, Developmental Trajectories of Impaired Community Functioning in Schizophrenia. JAMA PSYCHIAT 2016;73 (1):48-55 [PubMed]
Kraan T, van Dam DS, Velthorst E, de Ruigh EL, Nieman DH, Durston S, Schothorst P, van der Gaag M, de Haan L, Childhood trauma and clinical outcome in patients at ultra-high risk of transition to psychosis. SCHIZOPHR RES 2015;169 (1-3):193-198 [PubMed]
Kraan T, Velthorst E, Smit F, de Haan L, van der Gaag M, Trauma and recent life events in individuals at ultra high risk for psychosis: review and meta-analysis. SCHIZOPHR RES 2015;161 (2-3):143-149 [PubMed]
van Dam DS, van Nierop M, Viechtbauer W, Velthorst E, van Winkel R, Bruggeman R, Cahn W, de Haan L, Kahn RS, Meijer CJ, Myin-Germeys I, van Os J, Wiersma D, Childhood abuse and neglect in relation to the presence and persistence of psychotic and depressive symptomatology. PSYCHOL MED 2015;45 (7):1363-1377 [PubMed]
van der Meer FJ, Velthorst E [Contributors: Bruggeman R, Cahn W, de Haan L, Kahn RS, Meijer C, Myin-Germeys I, van Os J, Wiersma D]] , Course of cannabis use and clinical outcome in patients with non-affective psychosis: a 3-year follow-up study. PSYCHOL MED 2015;45 (9):1977-1988 [PubMed]
Velthorst E, Koeter M, van der Gaag M, Nieman DH, Fett AKJ, Smit F, Staring ABP, Meijer C, de Haan L, Adapted cognitive-behavioural therapy required for targeting negative symptoms in schizophrenia: meta-analysis and meta-regression. PSYCHOL MED 2015;45 (3):453-465 [PubMed]
Velthorst E, Reichenberg A, Rabinowitz J, Levine SZ, Study of resilience and environmental adversity in midlife health (STREAM). SOC PSYCH PSYCH EPID 2015;50 (12):1915-1922 [PubMed]
Wiltink S, Nelson B, Velthorst E, Wigman JTW, Lin A, Baksheev G, Cosgrave E, Ross M, Ryan J, Yung AR, The relationship between personality traits and psychotic like experiences in a large non-clinical adolescent sample. PERS INDIV DIFFER 2015;73:92-97
Wiltink S, Velthorst E, Nelson B, McGorry PM, Yung AR, Declining transition rates to psychosis: the contribution of potential changes in referral pathways to an ultra-high-risk service. EARLY INTERV PSYCHIA 2015;9 (3):200-206 [PubMed]
Boyette LL, van Dam D, Meijer C, Velthorst E, Cahn W, de Haan L, Kahn R, van Os J, Wiersma D, Bruggeman R, Myin-Germeys I, Personality compensates for impaired quality of life and social functioning in patients with psychotic disorders who experienced traumatic events. SCHIZOPHRENIA BULL 2014;40 (6):1356-1365 [PubMed]
Nieman DH, Ruhrmann S, Dragt S, Soen F, van Tricht MJ, Koelman JHTM, Bour LJ, Velthorst E, Becker HE, Weiser M, Linszen DH, de Haan L, Psychosis prediction: stratification of risk estimation with information-processing and premorbid functioning variables. SCHIZOPHRENIA BULL 2014;40 (6):1482-1490 [PubMed]
van Dam DS, Korver-Nieberg N, Velthorst E, Meijer CJ, de Haan L [Contributors: Kahn RS, de Haan L, van Os J, Wiersma D, Bruggeman R, Cahn W, Meijer CJ, Myin-Germeys I]] , Childhood maltreatment, adult attachment and psychotic symptomatology: a study in patients, siblings and controls. SOC PSYCH PSYCH EPID 2014;49 (11):1759-1767 [PubMed]
van der Meer FJ, Meijer JH, Meijer CJ, van den Brink W, Velthorst E [Contributors: Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I]] , Cognitive functioning associated with stimulant use in patients with non-affective psychosis, their unaffected siblings and healthy controls. PSYCHOL MED 2014;44 (9):1901-1911 [PubMed]
van Os J, Rutten BP, Myin-Germeys I, Delespaul P, Viechtbauer W, van Zelst C, Bruggeman R, Reininghaus U, Morgan C, Murray RM, Di Forti M, McGuire P, Valmaggia LR, Kempton MJ, Gayer-Anderson C, Hubbard K, Beards S, Stilo SA, Onyejiaka A, Bourque F, Modinos G, Tognin S, Calem M, O'Donovan MC, Owen MJ, Holmans P, Williams N, Craddock N, Richards A, Humphreys I, Meyer-Lindenberg A, Leweke FM, Tost H, Akdeniz C, Rohleder C, Bumb JM, Schwarz E, Alptekin K, Üçok A, Saka MC, Atbaşoğlu EC, Gülöksüz S, Gumus-Akay G, Cihan B, Karadağ H, Soygür H, Cankurtaran EŞ, Ulusoy S, Akdede B, Binbay T, Ayer A, Noyan H, Karadayı G, Akturan E, Ulaş H, Arango C, Parellada M, Bernardo M, Sanjuán J, Bobes J, Arrojo M, Santos JL, Cuadrado P, Rodríguez Solano JJ, Carracedo A, García Bernardo E, Roldán L, López G, Cabrera B, Cruz S, Díaz Mesa EM, Pouso M, Jiménez E, Sánchez T, Rapado M, González E, Martínez C, Sánchez E, Olmeda MS, de Haan L, Velthorst E, van der Gaag M, Selten JP, van Dam D, van der Ven E, van der Meer F, Messchaert E, Kraan T, Burger N, Leboyer M, Szoke A, Schürhoff F, Llorca PM, Jamain S, Tortelli A, Frijda F, Vilain J, Galliot AM, Baudin G, Ferchiou A, Richard JR, Bulzacka E, Charpeaud T, Tronche AM, de Hert M, van Winkel R, Decoster J, Derom C, Thiery E, Stefanis NC, Sachs G, Aschauer H, Lasser I, Winklbaur B, Schlögelhofer M, Riecher-Rössler A, Borgwardt S, Walter A, Harrisberger F, Smieskova R, Rapp C, Ittig S, Soguel-Dit-Piquard F, Studerus E, Klosterkötter J, Ruhrmann S, Paruch J, Julkowski D, Hilboll D, Sham PC, Cherny SS, Chen EYH, Campbell DD, Li M, Romeo-Casabona CM, Emaldi Cirión A, Urruela Mora A, Jones P, Kirkbride J, Cannon M, Rujescu D, Tarricone I, Berardi D, Bonora E, Seri M, Marcacci T, Chiri L, Chierzi F, Storbini V, Braca M, Minenna MG, Donegani I, Fioritti A, La Barbera D, La Cascia CE, Mulè A, Sideli L, Sartorio R, Ferraro L, Tripoli G, Seminerio F, Marinaro AM, McGorry P, Nelson B, Amminger GP, Pantelis C, Menezes PR, del-Ben CM, Gallo Tenan SH, Shuhama R, Ruggeri M, Tosato S, Lasalvia A, Bonetto C, Ira E, Nordentoft M, Krebs MO, Barrantes-Vidal N, Cristóbal P, Kwapil TR, Brietzke E, Bressan RA, Gadelha A, Maric NP, Andric S, Mihaljevic M, Mirjanic T, Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations. SCHIZOPHRENIA BULL 2014;40 (4):729-736 [PubMed]
van Tricht MJ, Ruhrmann S, Arns M, Müller R, Bodatsch M, Velthorst E, Koelman JHTM, Bour LJ, Zurek K, Schultze-Lutter F, Klosterkötter J, Linszen DH, de Haan L, Brockhaus-Dumke A, Nieman DH, Can quantitative EEG measures predict clinical outcome in subjects at Clinical High Risk for psychosis? A prospective multicenter study. SCHIZOPHR RES 2014;153 (1-3):42-47 [PubMed]
Velthorst E, de Haan L, Sociaal disfunctioneren van jongeren met een ultrahoog risico op het ontwikkelen van een eerste psychose. TIJDSCHR PSYCHIATR 2014;56 (1):40-49 [PubMed]
de Haan L, Velthorst E, Nieman DH, Becker HE, de Lange MA, van der Gaag M, Preventie van een psychotische aandoening: rijp voor klinische toepassing?. NED TIJDSCHR GENEESKD 2013;157 (9):A5641 [PubMed]
Fusar-Poli P, Borgwardt S, Bechdolf A, Addington J, Riecher-Rössler A, Schultze-Lutter F, Keshavan M, Wood S, Ruhrmann S, Seidman LJ, Valmaggia L, Cannon T, Velthorst E, de Haan L, Cornblatt B, Bonoldi I, Birchwood M, McGlashan T, Carpenter W, McGorry P, Klosterkötter J, McGuire P, Yung A, The Psychosis High-Risk State A Comprehensive State-of-the-Art Review. JAMA PSYCHIAT 2013;70 (1):107-120 [PubMed]
Nieman DH, Velthorst E, Becker HE, de Haan L, Dingemans PM, Linszen DH, Birchwood M, Patterson P, Salokangas RKR, Heinimaa M, Heinz A, Juckel G, von Reventlow HG, Morrison A, Schultze-Lutter F, Klosterkötter J, Ruhrmann S [Contributors: McGorry PD, McGlashan TH, Knapp M, van de Fliert R, Klaassen R, Picker H, Neumann M, Brockhaus-Dumke A, Pukrop R, Svirskis T, Huttunen J, Laine T, Ilonen T, Ristkari T, Hietala J, Skeate A, Gudlowski Y, Ozgürdal S, French P, Stevens H]] , The Strauss and Carpenter Prognostic Scale in subjects clinically at high risk of psychosis. ACTA PSYCHIAT SCAND 2013;127 (1):53-61 [PubMed]
Simon AE, Borgwardt S, Riecher-Rössler A, Velthorst E, de Haan L, Fusar-Poli P, Moving beyond transition outcomes: meta-analysis of remission rates in individuals at high clinical risk for psychosis. PSYCHIAT RES 2013;209 (3):266-272 [PubMed]
Velthorst E, Derks EM, Schothorst P, Becker H, Durston S, Ziermans T, Nieman DH, de Haan L, Quantitative and qualitative symptomatic differences in individuals at Ultra-High Risk for psychosis and healthy controls. PSYCHIAT RES 2013;210 (2):432-437 [PubMed]
Velthorst E, Levine SZ, Henquet C, de Haan L, van Os J, Myin-Germeys I, Reichenberg A, To cut a short test even shorter: reliability and validity of a brief assessment of intellectual ability in schizophrenia--a control-case family study. COGN NEUROPSYCHIATRY 2013;18 (6):574-593 [PubMed]
Velthorst E, Nelson B, O'Connor K, Mossaheb N, de Haan L, Bruxner A, Simmons MB, Yung AR, Thompson A, History of trauma and the association with baseline symptoms in an Ultra-High Risk for psychosis cohort. PSYCHIAT RES 2013;210 (1):75-81 [PubMed]
Velthorst E, Nelson B, Wiltink S, de Haan L, Wood SJ, Lin A, Yung AR, Transition to first episode psychosis in ultra high risk populations: does baseline functioning hold the key?. SCHIZOPHR RES 2013;143 (1):132-137 [PubMed]
Abbs B, Achalia RM, Adelufosi AO, Aktener AY, Beveridge NJ, Bhakta SG, Blackman RK, Bora E, Byun MS, Cabanis M, Carrion R, Castellani CA, Chow TJ, Dmitrzak-Weglarz M, Gayer-Anderson C, Gomes FV, Haut K, Hori H, Kantrowitz JT, Kishimoto T, Lee FHF, Lin A, Palaniyappan L, Quan M, Rubio MD, Ruiz de Azúa S, Sahoo S, Strauss GP, Szczepankiewicz A, Thompson AD, Trotta A, Tully LM, Uchida H, Velthorst E, Young JW, O'Shea A, DeLisi LE, The 3rd Schizophrenia International Research Society Conference, 14-18 April 2012, Florence, Italy: Summaries of oral sessions. SCHIZOPHR RES 2012;141 (1):E1-E24 [PubMed]
van Dam DS, van der Ven E, Velthorst E, Selten JP, Morgan C, de Haan L, Childhood bullying and the association with psychosis in non-clinical and clinical samples: a review and meta-analysis. PSYCHOL MED 2012;42 (12):2463-2474 [PubMed]
van der Meer FJ, Velthorst E, Meijer CJ, Machielsen MWJ, de Haan L, Cannabis Use in Patients at Clinical High Risk of Psychosis: Impact on Prodromal Symptoms and Transition to Psychosis. CURR PHARM DESIGN 2012;18 (32):5036-5044 [PubMed]
Velthorst E, Meijer C [Contributors: Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I]] , The association between social anhedonia, withdrawal and psychotic experiences in general and high-risk populations. SCHIZOPHR RES 2012;138 (2-3):290-294 [PubMed]
Velthorst E, Nieman DH, Veling W, Klaassen RM, Dragt S, Rietdijk J, Ising H, Wunderink L, Linszen DH, de Haan L, van der Gaag M, Ethnicity and baseline symptomatology in patients with an At Risk Mental State for psychosis. PSYCHOL MED 2012;42 (2):247-256 [PubMed]
Klaassen RMC, Velthorst E, Nieman DH, de Haan L, Becker HE, Dingemans PM, van de Fliert JR, van der Gaag M, Linszen DH, Factor analysis of the scale of prodromal symptoms: differentiating between negative and depression symptoms. PSYCHOPATHOLOGY 2011;44 (6):379-385 [PubMed]
Simon AE, Velthorst E, Nieman DH, Linszen D, Umbricht D, de Haan L, Ultra high-risk state for psychosis and non-transition: a systematic review. SCHIZOPHR RES 2011;132 (1):8-17 [PubMed]
Velthorst E. The lonely soul wanders. On the role of impaired social functioning in the prediction of first psychosis. s.l.: s.n.; 2011. 191p. ISBN 9789090263083 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Linszen DH, de Haan L; copromotor(s): Nieman DH)
Velthorst E, Nieman DH, Klaassen RMC, Becker HE, Dingemans PM, Linszen DH, de Haan L, Three-year course of clinical symptomatology in young people at ultra high risk for transition to psychosis. ACTA PSYCHIAT SCAND 2011;123 (1):36-42 [PubMed]
Velthorst E, Nieman DH, Meijer C, Linszen D, de Haan L, Social Disability at Admission for a First Psychosis Does Not Predict Clinical Outcome at 5-Year Follow-Up. J NERV MENT DIS 2011;199 (7):510-512 [PubMed]
Becker HE, Nieman DH, Wiltink S, Dingemans PM, van de Fliert JR, Velthorst E, de Haan L, van Amelsvoort TA, Linszen DH, Neurocognitive functioning before and after the first psychotic episode: does psychosis result in cognitive deterioration?. PSYCHOL MED 2010;40 (10):1599-1606 [PubMed]
Velthorst E, Nieman DH, Linszen D, Becker H, de Haan L, Dingemans PM, Birchwood M, Patterson P, Salokangas RKR, Heinimaa M, Heinz A, Juckel G, von Reventlow HG, French P, Stevens H, Schultze-Lutter F, Klosterkötter J, Ruhrmann S, Disability in people clinically at high risk of psychosis. BRIT J PSYCHIAT 2010;197 (4):278-284 [PubMed]
Velthorst E, Nieman DH, Becker HE, van de Fliert R, Dingemans PM, Klaassen R, de Haan L, van Amelsvoort T, Linszen DH, Baseline differences in clinical symptomatology between ultra high risk subjects with and without a transition to psychosis. SCHIZOPHR RES 2009;109 (1-3):60-65 [PubMed]
Key publications

Velthorst E, Nieman DH, Linszen D, Becker H, de Haan L, Dingemans PM, Birchwood M, Patterson P, Salokangas RKR, Heinimaa M, Heinz A, Juckel G, von Reventlow HG, French P, Stevens H, Schultze-Lutter F, Klosterkötter J, Ruhrmann S, Disability in people clinically at high risk of psychosis. BRIT J PSYCHIAT 2010;197 (4):278-284 [PubMed]
Velthorst E, Nieman DH, Becker HE, van de Fliert R, Dingemans PM, Klaassen R, de Haan L, van Amelsvoort T, Linszen DH, Baseline differences in clinical symptomatology between ultra high risk subjects with and without a transition to psychosis. SCHIZOPHR RES 2009;109 (1-3):60-65 [PubMed]
Velthorst E, Nieman DH, Veling W, Klaassen RM, Dragt S, Rietdijk J, Ising H, Wunderink L, Linszen DH, de Haan L, van der Gaag M, Ethnicity and baseline symptomatology in patients with an At Risk Mental State for psychosis. PSYCHOL MED 2012;42 (2):247-256 [PubMed]


All Publications

Research programmes

Prof. dr. L. de Haan (Recent onset schizophrenia)

Other research related activities
  • None reported
Current research funding
  • None reported