Researchers

  • Male

Dr. M. Figee MD PhD

Position: Postdoc
Main activities: Patient care, Research
Specialisation: obsessive-compulsive disorder, deep brain stimulation, neuroimaging
foto
Focus of research:

Investigating brain dynamics of compulsivity and the effects of deep brain stimulation.

AMC themes: Neurological & Psychiatric Disorders
Departments: Psychiatry: Adult Psychiatry
dell'Osso B, Benatti B, Arici C, Palazzo C, Altamura AC, Hollander E, Fineberg N, Stein DJ, Nicolini H, Lanzagorta N, Marazziti D, Pallanti S, van Ameringen M, Lochner C, Karamustafalioglu O, Hranov L, Figee M, Drummond L, Rodriguez CI, Grant J, Denys D, Menchon JM, Zohar J, Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). CNS SPECTRUMS 2017;ahead of print [PubMed]
Dell'Osso B, Benatti B, Rodriguez CI, Arici C, Palazzo C, Altamura AC, Hollander E, Fineberg N, Stein DJ, Nicolini H, Lanzagorta N, Marazziti D, Pallanti S, van Ameringen M, Lochner C, Karamustafalioglu O, Hranov L, Figee M, Drummond L, Grant J, Denys D, Cath D, Menchon JM, Zohar J, Obsessive-compulsive disorder in the elderly: A report from the International College of Obsessive-Compulsive Disorders (ICOCS). EUR PSYCHIAT 2017;45:36-40 [PubMed]
Graat I, Figee M, Denys D, The application of deep brain stimulation in the treatment of psychiatric disorders. INT REV PSYCHIATR 2017;29 (2):178-190 [PubMed]
Ooms P, Blankers M, Figee M, Bergfeld IO, van den Munckhof P, Schuurman PR, Denys D, Cost-effectiveness of deep brain stimulation versus treatment as usual for obsessive-compulsive disorder. BRAIN STIMUL 2017;10 (4):836-842 [PubMed]
Slagter HA, Mazaheri A, Reteig LC, Smolders R, Figee M, Mantione M, Schuurman PR, Denys D, Contributions of the Ventral Striatum to Conscious Perception: An Intracranial EEG Study of the Attentional Blink. J NEUROSCI 2017;37 (5):1081-1089 [PubMed]
Bahramisharif A , Mazaheri A, Levar N, Richard Schuurman P, Figee M, Denys D, Deep Brain Stimulation Diminishes Cross-Frequency Coupling in Obsessive-Compulsive Disorder. BIOL PSYCHIAT 2016;80 (7):E57-E58 [PubMed]
Bergfeld IO, Mantione M, Hoogendoorn MLC, Ruhé HG , Notten P, van Laarhoven J, Visser I , Figee M, de Kwaasteniet BP, Horst F, Schene AH, van den Munckhof P, Beute G, Schuurman R, Denys D, Deep Brain Stimulation of the Ventral Anterior Limb of the Internal Capsule for Treatment-Resistant Depression: A Randomized Clinical Trial. JAMA PSYCHIAT 2016;73 (5):456-464 [PubMed]
Boel JA, Odekerken VJJ, Geurtsen GJ, Schmand BA, Cath DC, Figee M, van den Munckhof P, de Haan RJ, Schuurman PR, de Bie RMA [Contributors: Odekerken VJJ, Boel JA, van Laar T, van Dijk JMC, Mosch A, Hoffmann CFE, Nijssen PCG, Beute GN, van Vugt JPP, Lenders MWPM, Contarino MF, Bour LJ, van den Munckhof P, Geurtsen GJ, Schmand BA, de Haan RJ, Schuurman PR, de Bie RMA]] , Psychiatric and social outcome after deep brain stimulation for advanced Parkinson's disease. MOVEMENT DISORD 2016;31 (3):409-413 [PubMed]
Boel JA, Odekerken VJJ, Schmand BA, Geurtsen GJ, Cath DC, Figee M, van den Munckhof P, de Haan RJ, Schuurman PR, de Bie RMA [Contributors: Odekerken VJJ, Boel JA, van Laar T, van Dijk JMC, Mosch A, Hoffmann CFE, Nijssen PCG, van Asseldonk T, Beute GN, van Vugt JPP, Lenders MWPM, Fiorella Contarino M, Bour LJ, Geurtsen GJ, van den Munckhof P, Schmand BA, de Haan RJ, Schuurman PR, de Bie RMA]] , Cognitive and psychiatric outcome 3 years after globus pallidus pars interna or subthalamic nucleus deep brain stimulation for Parkinson's disease. PARKINSONISM RELAT D 2016;33:90-95 [PubMed]
de Koning PP. Rapid mechanisms of DBS in OCD. S.l.: s.n.; 2016. 179p. ISBN 978-94-6295-497-7 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Denys DAJP; copromotor(s): Storosum JG, Figee M)
de Koning PP, Figee M, Endert E, van den Munckhof P, Schuurman PR, Storosum JG, Denys D, Fliers E, Rapid effects of deep brain stimulation reactivation on symptoms and neuroendocrine parameters in obsessive-compulsive disorder. TRANSL PSYCHIAT 2016;6:e722 [PubMed]
dell'Osso B, Benatti B, Hollander E, Fineberg N, Stein DJ, Lochner C, Nicolini H, Lanzagorta N, Palazzo C, Altamura AC, Marazziti D, Pallanti S, van Ameringen M, Karamustafalioglu O, Drummond LM, Hranov L, Figee M, Grant JE, Zohar J, Denys D, Menchon JM, Childhood, adolescent and adult age at onset and related clinical correlates in obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). INT J PSYCHIAT CLIN 2016;20 (4):210-217 [PubMed]
de Sain-van der Velden MGM, Jans JJ, Figee M, Engelen M, Prinsen HCMT, Verhoeven-Duif NM, van Kuilenburg ABP, Visser G, Vinkers CH, Stofwisselingsziekten binnen de psychiatrie. TIJDSCHR PSYCHIATR 2016;58 (5):402-406 [PubMed]
Feenstra MGP, Klompmakers A, Figee M, Fluitman S, Vulink N, Westenberg HGM, Denys D, Prazosin addition to fluvoxamine: A preclinical study and open clinical trial in OCD. EUR NEUROPSYCHOPHARM 2016;26 (2):310-319 [PubMed]
Figee M, Pattij T, Willuhn I, Luigjes J, van den Brink W, Goudriaan A, Potenza MN, Robbins TW, Denys D, Compulsivity in obsessive-compulsive disorder and addictions. EUR NEUROPSYCHOPHARM 2016;26 (5):856-868 [PubMed]
Giffin M, Figee M, Denys D. Deep brain stimulation for the treatment of obsessive-compulsive disorder in: Hamani C, Holtzheimer P, Lozano AM, Mayberg H, editors. Neuromodulation in Psychiatry. S.l.: John Wiley & Sons; 2016., p. 295
Grassi G, Figee M, Stratta P, Rossi A, Pallanti S, Response to Cognitive impulsivity and the behavioral addiction model of obsessive-compulsive disorder: Abramovitch and McKay (2016). J BEHAV ADDICT 2016;5 (3):398-400 [PubMed]
Luigjes J, Figee M, Tobler PN, van den Brink W, de Kwaasteniet B, van Wingen G, Denys D, Doubt in the Insula: Risk Processing in Obsessive-Compulsive Disorder. FRONT HUM NEUROSCI 2016;10:283 [PubMed]
Menchón JM, van Ameringen M, dell'Osso B, Denys D, Figee M, Grant JE, Hollander E, Marazziti D, Nicolini H, Pallanti S, Ruck C, Shavitt R, Stein DJ, Andersson E, Bipeta R, Cath DC, Drummond L, Feusner J, Geller DA, Hranov G, Lochner C, Matsunaga H, McCabe RE, Mpavaenda D, Nakamae T, O'Kearney R, Pasquini M, Pérez Rivera R, Poyurovsky M, Real E, do Rosário MC, Soreni N, Swinson RP, Vulink N, Zohar J, Fineberg N, Standards of care for obsessive-compulsive disorder centres. INT J PSYCHIAT CLIN 2016;20 (3):204-208 [PubMed]
Odekerken VJJ, Boel JA, Schmand BA, de Haan RJ, Figee M, van den Munckhof P, Schuurman PR, de Bie RMA [Contributors: de Bie RMA, Bour L, Contarino MF, de Haan RJ, Iwan M, Mink MSJ, van den Munckhof P, Odekerken VJJ , Postma M, Schmand BA, Scholten MN, Schuurman PR, van Laar T, van Dijk JMC, Hoffmann CFE, Mosch A, Beute GN, Nijssen PCG, van Asseldonk T, Lenders MWPM, van Vugt JPP]] , GPi vs STN deep brain stimulation for Parkinson disease: Three-year follow-up. NEUROLOGY 2016;86 (8):755-761 [PubMed]
Vulink NC, Planting RS, Figee M, Booij J, Denys D, Reduced striatal dopamine D2/3 receptor availability in Body Dysmorphic Disorder. EUR NEUROPSYCHOPHARM 2016;26 (2):350-356 [PubMed]
Figee M, Schuurman R, Denys D, Challenges with Meta-Analysis in Deep Brain Stimulation. STEREOT FUNCT NEUROS 2015;93 (2):147 [PubMed]
Grassi G, Pallanti S, Righi L, Figee M, Mantione M, Denys D, Piccagliani D, Rossi A, Stratta P, Think twice: Impulsivity and decision making in obsessive-compulsive disorder. J BEHAV ADDICT 2015;4 (4):263-272 [PubMed]
Mantione M, Nieman D, Figee M, van den Munckhof P, Schuurman R, Denys D, Cognitive effects of deep brain stimulation in patients with obsessive-compulsive disorder. J PSYCHIATR NEUROSCI 2015;40 (6):378-386 [PubMed]
van Westen M, Rietveld E, Figee M, Denys D, Clinical Outcome and Mechanisms of Deep Brain Stimulation for Obsessive-Compulsive Disorder. CURR BEHAV NEUROSCI REP 2015;2 (2):41-48 [PubMed]
Baas JMP, Klumpers F, Mantione MH, Figee M, Vulink NC, Schuurman PR, Mazaheri A, Denys D, No impact of deep brain stimulation on fear-potentiated startle in obsessive-compulsive disorder. FRONT BEHAV NEUROSCI 2014;8:305 [PubMed]
Bais M, Figee M, Denys D, Neuromodulation in obsessive-compulsive disorder. PSYCHIAT CLIN N AM 2014;37 (3):393-413 [PubMed]
Figee M, de Koning P, Klaassen S, Vulink N, Mantione M, van den Munckhof P, Schuurman R , van Wingen G, van Amelsvoort T, Booij J, Denys D, Deep brain stimulation induces striatal dopamine release in obsessive-compulsive disorder. BIOL PSYCHIAT 2014;75 (8):647-652 [PubMed]
Figee M, Luigjes J, Smolders R, Valencia-Alfonso CE, van Wingen G, de Kwaasteniet B, Mantione M, Ooms P, de Koning P, Vulink N, Levar N, Droge L, van den Munckhof P, Schuurman PR, Nederveen A, van den Brink W, Mazaheri A, Vink M, Denys D, Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder (vol 16, pg 386, 2013). NAT NEUROSCI 2014;17 (9):1286 [PubMed]
Mantione M, Figee M, Denys D, A case of musical preference for Johnny Cash following deep brain stimulation of the nucleus accumbens. FRONT BEHAV NEUROSCI 2014;8:152 [PubMed]
Mantione M, Nieman DH, Figee M, Denys D, Cognitive-behavioural therapy augments the effects of deep brain stimulation in obsessive-compulsive disorder. PSYCHOL MED 2014;44 (16):3515-3522 [PubMed]
Ooms P, Blankers M, Figee M, Mantione M, van den Munckhof P, Schuurman PR, Denys D, Rebound of affective symptoms following acute cessation of deep brain stimulation in obsessive-compulsive disorder. BRAIN STIMUL 2014;7 (5):727-731 [PubMed]
Ooms P, Mantione M, Figee M, Schuurman PR, van den Munckhof P, Denys D, Deep brain stimulation for obsessive-compulsive disorders: long-term analysis of quality of life. J NEUROL NEUROSUR PS 2014;85 (2):153-158 [PubMed]
de Koning PP, Figee M, Endert E, Storosum JG, Fliers E, Denys D, Deep brain stimulation for obsessive-compulsive disorder is associated with cortisol changes. PSYCHONEUROENDOCRINO 2013;38 (8):1455-1459 [PubMed]
Denys D, de Vries F, Cath D, Figee M, Vulink N, Veltman DJ, van der Doef TF, Boellaard R, Westenberg H, van Balkom A, Lammertsma AA, van Berckel BNM, Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder. EUR NEUROPSYCHOPHARM 2013;23 (11):1423-1431 [PubMed]
Figee M. Moving the brain. Neuroimaging motivational changes of deep brain stimulation in obsessive-compulsive disorder. s.l.: s.n.; 2013. 256p. ISBN 9789462282247 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Denys DAJP; copromotor(s): van Wingen GA)
Figee M, Luigjes J, Smolders R, Valencia-Alfonso CE, van Wingen G, de Kwaasteniet B, Mantione M, Ooms P, de Koning P, Vulink N, Levar N, Droge L, van den Munckhof P, Schuurman PR, Nederveen A, van den Brink W, Mazaheri A, Vink M, Denys D, Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder. NAT NEUROSCI 2013;16 (4):386-387 [PubMed]
Figee M, Wielaard I, Mazaheri A, Denys D, Neurosurgical targets for compulsivity: what can we learn from acquired brain lesions?. NEUROSCI BIOBEHAV R 2013;37 (3):328-339 [PubMed]
Polak AR, Witteveen AB, Mantione M, Figee M, de Koning P, Olff M, van den Munckhof P, Schuurman PR, Denys D, Deep brain stimulation for obsessive-compulsive disorder affects language: a case report. NEUROSURGERY 2013;73 (5):E907-10; discussion E910 [PubMed]
Smolders R, Mazaheri A, van Wingen G, Figee M, de Koning PP, Denys D, Deep brain stimulation targeted at the nucleus accumbens decreases the potential for pathologic network communication. BIOL PSYCHIAT 2013;74 (10):e27-e28 [PubMed]
van den Munckhof P, Bosch DA, Mantione MHM, Figee M, Denys DAJP, Schuurman PR, Active stimulation site of nucleus accumbens deep brain stimulation in obsessive-compulsive disorder is localized in the ventral internal capsule. ACTA NEUROCHIR 2013;117 (Suppl.):53-59 [PubMed]
Blom RM, Figee M, Vulink NCC, Denys D. Electroconvulsive Therapy, Transcranial Magnetic Stimulation and Deep Brain Stimulation in OCD in: Zohar J, editors. Obsessive-Compulsive Disorder: Current Science and Clinical Practice. West Sussex: John Wiley & Sons, Ltd; 2012., p. 75
Cohen MX, Bour L, Mantione M, Figee M, Vink M, Tijssen MAJ, van Rootselaar AF, van den Munckhof P, Schuurman PR, Denys D, Top-down-directed synchrony from medial frontal cortex to nucleus accumbens during reward anticipation. HUM BRAIN MAPP 2012;33 (1):246-252 [PubMed]
de Koning PP, Munckhof van den P , Figee M, Schuurman PR, Denys D. Deep brain stimulation in obsessive-compulsive disorder targeted at the nucleus accumbens in: Denys D, Feenstra MG, Schuurman PR, editors. Deep Brain Stimulation: A New Frontier in Psychiatry. Berlin; Heidelberg: Springer; 2012., p. 43
Figee M, van den Munckhof P, Schuurman PR, Denys D. Neuroimaging deep brain stimulation in psychiatric disorders in: Denys D, Feenstra MG, Schuurman PR, editors. Deep Brain Stimulation: A New Frontier in Psychiatry. Berlin; Heidelberg: Springer; 2012., p. 225-239
Polak AR, van der Paardt JW, Figee M, Vulink N, de Koning P, Olff M, Denys D, Compulsive carnival song whistling following cardiac arrest: a case study. BMC PSYCHIATRY 2012;12 (1):75 [PubMed]
Polak AR, Witteveen AB, Visser RS, Opmeer BC, Vulink N, Figee M, Denys D, Olff M, Comparison of the effectiveness of trauma-focused cognitive behavioral therapy and paroxetine treatment in PTSD patients: design of a randomized controlled trial. BMC PSYCHIATRY 2012;12 (1):166 [PubMed]
Vulink NC, Figee M, Denys D, Revisión de los antipsicóticos atípicos en la ansiedad. PSIQUIATRIA BIOLÓGICA 2012;19 (Supl. 1):21-41
Blom RM, Figee M, Vulink N, Denys D. ECT, TMS, and DBS in OCD in: Maj M, Norman S, Ahmed O, Zohar J, editors. Obsessive compulsive disorder. 2nd ed.. S.l.: Wiley-Blackwell; 2011., p. -
Blom RM, Figee M, Vulink N, Denys D, Update on repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: different targets. CURR PSYCHIAT REP 2011;13 (4):289-294 [PubMed]
da Silva Alves F, Schmitz N, Figee M, Abeling N, Hasler G, van der Meer J, Nederveen A, de Haan L, Linszen D, van Amelsvoort T, Dopaminergic modulation of the human reward system: a placebo-controlled dopamine depletion fMRI study. J PSYCHOPHARMACOL 2011;25 (4):538-549 [PubMed]
de Koning PP, Figee M, van den Munckhof P, Schuurman PR, Denys D, Current status of deep brain stimulation for obsessive-compulsive disorder: a clinical review of different targets. CURR PSYCHIAT REP 2011;13 (4):274-282 [PubMed]
Figee M, Booij J, Denys D. Molecular imaging of Obsessive compulsive disorder in: Shenton M E., Turetsky B I., editors. Understandig Neuropsychiatric Disorders: Insights from Neuroimaging. S.l.: Cambridge University Press; 2010., p. -
Figee M, Vink M, de Geus F, Vulink N, Veltman DJ, Westenberg H, Denys D, Dysfunctional Reward Circuitry in Obsessive-Compulsive Disorder. BIOL PSYCHIAT 2011;69 (9):867-874 [PubMed]
Mantione M, Figee M, Denys D. [Deep brain stimulation for treatment refractory obsessive-compulsive disorder] in: van Balkom AJLM, Oosterbaan D, Visser S, van Vliet IM, editors. Handboek Angststoornissen. Utrecht: De Tijdstroom; 2011., p. 431
Vulink NCC, Figee M, Denys D, Review of atypical antipsychotics in anxiety. EUR NEUROPSYCHOPHARM 2011;21 (6):429-449 [PubMed]
Denys D, Mantione M, Figee M, van den Munckhof P, Koerselman F, Westenberg H, Bosch A, Schuurman R, Deep Brain Stimulation of the Nucleus Accumbens for Treatment-Refractory Obsessive-Compulsive Disorder. ARCH GEN PSYCHIAT 2010;67 (10):1061-1068 [PubMed]
Figee M, Mantione M, van den Munckhof P, Schuurman R, Denys D, Targets for Deep Brain Stimulation in Obsessive-Compulsive Disorder. PSYCHIAT ANN 2010;40 (10):492-498
Figee M, Denys D, New pharmacotherapeutic approaches to obsessive-compulsive disorder. CNS SPECTRUMS 2009;14 (2 Suppl 3):13-23 [PubMed]
Spitzer U, Figee M, Mantione M, Denys D, To feel free or to be free? To the psychology of experience of patients with obsessive compulsive disorders under deep brain stimulation. NERVENHEILKUNDE 2009;28 (9):634-642
da Silva Alves F, Figee M, van Amelsvoort T, Veltman D, de Haan L, The revised dopamine hypothesis of schizophrenia: evidence from pharmacological MRI studies with atypical antipsychotic medication. PSYCHOPHARMACOL BULL 2008;41 (1):121-132 [PubMed]
van Amelsvoort T, Zinkstok J, Figee M, Daly E, Morris R, Owen MJ, Murphy KC, de Haan L, Linszen DH, Glaser B, Murphy DGM, Effects of a functional COMT polymorphism on brain anatomy and cognitive function in adults with velo-cardio-facial syndrome. PSYCHOL MED 2008;38 (1):89-100 [PubMed]
Key publications

Figee M, Luigjes J, Smolders R, Valencia-Alfonso CE, van Wingen G, de Kwaasteniet B, Mantione M, Ooms P, de Koning P, Vulink N, Levar N, Droge L, van den Munckhof P, Schuurman PR, Nederveen A, van den Brink W, Mazaheri A, Vink M, Denys D, Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder. NAT NEUROSCI 2013;16 (4):386-387 [PubMed]
Figee M, de Koning P, Klaassen S, Vulink N, Mantione M, van den Munckhof P, Schuurman R , van Wingen G, van Amelsvoort T, Booij J, Denys D, Deep brain stimulation induces striatal dopamine release in obsessive-compulsive disorder. BIOL PSYCHIAT 2014;75 (8):647-652 [PubMed]
Figee M, Vink M, de Geus F, Vulink N, Veltman DJ, Westenberg H, Denys D, Dysfunctional Reward Circuitry in Obsessive-Compulsive Disorder. BIOL PSYCHIAT 2011;69 (9):867-874 [PubMed]


All Publications

Research programmes

Prof. dr. D.A.J.P. Denys (Deep Brain Stimulation and Obsessive-Compulsive Disorders)

Other research related activities
  • Membership of medical or scientific committee, AMC, Medical Ethical Comittee
  • Board of directors / Trustees / Supervisory board, International College of Obsessive Compulsive Disorders
Current research funding
  • None reported