Researchers

  • Female

L. Nawijn MSc

Position: PhD student
Main activities: Research
Specialisation: psychotrauma, PTSD, oxytocin, stress, neuroimaging, psychoneuroendocrinology
foto
Focus of research:

My research focusses on the neurobiological effects of oxytocin in PTSD.

I am involved in the BOOSTER and the BONDS study, both randomized, double-blind, placebo-controlled trials. In the BOOSTER study we use fMRI to investigate the effects of a single dosage intranasal oxytocin administration on neural activity and behaviour related to emotion- and reward processing in individuals with and without PTSD. In the BONDS study we investigate the effects of single intranasal oxytocin administration on brain activity in recently trauma-exposed individuals. Furthermore, we look at the longitudinal effects of a week of intranasal oxytocin administration on psychological wellbeing and the development of psychopathology in recently trauma-exposed individuals. In both the BONDS and the BOOSTER study we also look into (epi)genetic, psychological, physiological and endocrinological factors that might influence the effects of oxytocin.

AMC themes: Neurological & Psychiatric Disorders
Departments: Psychiatry: Adult Psychiatry
Koch SBJ, van Zuiden M, Nawijn L, Frijling JL, Veltman DJ, Olff M, Decreased uncinate fasciculus tract integrity in male and female patients with PTSD: a diffusion tensor imaging study. J PSYCHIATR NEUROSCI 2017;42 (5):331-342 [PubMed]
Nawijn L. Peril or Pleasure: Reward and salience neurocircuitry and the effects of intranasal oxytocin in posttraumatic stress disorder. S.l.: s.n.; 2017. 253p. ISBN 97894 62996052 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Olff M; copromotor(s): Veltman DJ, van Zuiden M)
Nawijn L, van Zuiden M, Koch SBJ, Frijling JL, Veltman DJ, Olff M, Intranasal oxytocin increases neural responses to social reward in post-traumatic stress disorder. SOC COGN AFFECT NEUR 2017;12 (2):212-223 [PubMed]
van Zuiden M, Frijling JL, Nawijn L, Koch SBJ, Goslings JC, Luitse JS, Biesheuvel TH, Honig A, Veltman DJ, Olff M, Intranasal Oxytocin to Prevent Posttraumatic Stress Disorder Symptoms: A Randomized Controlled Trial in Emergency Department Patients. BIOL PSYCHIAT 2017;81 (12):1030-1040 [PubMed]
Frijling JL, van Zuiden M, Koch SBJ, Nawijn L, Veltman DJ, Olff M, Effects of intranasal oxytocin on amygdala reactivity to emotional faces in recently trauma-exposed individuals. SOC COGN AFFECT NEUR 2016;11 (2):327-336 [PubMed]
Frijling JL, van Zuiden M, Koch SBJ, Nawijn L, Veltman DJ, Olff M, Intranasal Oxytocin Affects Amygdala Functional Connectivity after Trauma Script-Driven Imagery in Distressed Recently Trauma-Exposed Individuals. NEUROPSYCHOPHARMACOL 2016;41 (5):1286-1296 [PubMed]
Koch SBJ, van Zuiden M, Nawijn L, Frijling JL, Veltman DJ, Olff M, ABERRANT RESTING-STATE BRAIN ACTIVITY IN POSTTRAUMATIC STRESS DISORDER: A META-ANALYSIS AND SYSTEMATIC REVIEW. DEPRESS ANXIETY 2016;33 (7):592-605 [PubMed]
Koch SBJ, van Zuiden M, Nawijn L, Frijling JL, Veltman DJ, Olff M, Intranasal Oxytocin Normalizes Amygdala Functional Connectivity in Posttraumatic Stress Disorder. NEUROPSYCHOPHARMACOL 2016;41 (8):2041-2051 [PubMed]
Koch SB, van Zuiden M, Nawijn L, Frijling JL, Veltman DJ, Olff M, Intranasal Oxytocin Administration Dampens Amygdala Reactivity towards Emotional Faces in Male and Female PTSD Patients. NEUROPSYCHOPHARMACOL 2016;41 (6):1495-1504 [PubMed]
Nawijn L, van Zuiden M, Koch SBJ, Frijling JL, Veltman DJ, Olff M, Intranasal oxytocin enhances neural processing of monetary reward and loss in post-traumatic stress disorder and traumatized controls. PSYCHONEUROENDOCRINO 2016;66:228-237 [PubMed]
Nawijn L, van Zuiden M, Frijling JL, Koch SBJ, Veltman DJ, Olff M, Reward functioning in PTSD: a systematic review exploring the mechanisms underlying anhedonia. NEUROSCI BIOBEHAV R 2015;51:189-204 [PubMed]
Olff M, van Zuiden M, Koch SBJ, Nawijn L, Frijling JL, Veltman DJ, Intranasal oxytocin: miracle cure after trauma?. EUR J PSYCHOTRAUMATO 2015;6 (1):27631
Frijling JL, van Zuiden M, Koch SBJ, Nawijn L, Goslings JC, Luitse JS, Biesheuvel TH, Honig A, Bakker FC, Denys D, Veltman DJ, Olff M, Efficacy of oxytocin administration early after psychotrauma in preventing the development of PTSD: study protocol of a randomized controlled trial. BMC PSYCHIATRY 2014;14 (1):92 [PubMed]
Koch SBJ, van Zuiden M, Nawijn L, Frijling JL, Veltman DJ, Olff M, Intranasal oxytocin as strategy for medication-enhanced psychotherapy of PTSD: salience processing and fear inhibition processes. PSYCHONEUROENDOCRINO 2014;40:242-256 [PubMed]
Olff M, Koch SBJ, Nawijn L, Frijling JL, van Zuiden M, Veltman DJ, Social support, oxytocin, and PTSD. EUR J PSYCHOTRAUMATO 2014;5 (1):26513 [PubMed]
Peters LWH, Nawijn L, van Kesteren NMC, How adolescents with diabetes experience social support from friends: two qualitative studies. SCIENTIFICA 2014;2014:415849 [PubMed]
Frijling JL, van Zuiden M, Koch S, Nawijn L, Veltman D, Olff M. Promoting resilience after trauma: clinical applications of intranasal oxytocin and affiliation development in preventing PTSD in: Kent M, Davis M C., Reich J W., editors. Handbook of Resilience: Approaches to Stress and Trauma. New York: Routledge; 2013., p. 299
Key publications



All Publications

Curriculum Vitae

PhD - Neurobiological effects of oxytocin in PTSD patients
AMC, University of Amsterdam, Department of Psychiatry, Amsterdam, the Netherlands, 2011-present
Supervisors: Miranda Olff, PhD, Dick J. Veltman, PhD, Mirjam van Zuiden, PhD

Researcher - Youth Healthcare
TNO, Leiden, the Netherlands, 2008 - 2011

Research Master degree - Neurosciences
VU University, Amsterdam, the Netherlands, 2005 - 2008

Bachelor degree - Biological Psychology
VU University, Amsterdam & Leiden University, Leiden, the Netherlands, 2000 - 2005

Research programmes
Other research related activities
  • None reported
Current research funding
  • None reported