Scope of research

The scope of research at the department of radiology is to improve existing and develop new imaging techniques and methods and image guided intervention. This encompasses the technical development as well as the evaluation of accuracy, reproducibility, efficiency, implementation, and patient acceptance of new techniques and methods. With current and new imaging techniques and methods, large data sets are acquired necessitating the development of image processing techniques for optimized and efficient data evaluation.

Principal investigators
At this moment there are five major research lines led by a principal investigator.

  • Cardiovascular: Prof. J.A. Reekers, MD, PhD
    Research is aimed at treatment of patients with critical limb ischemia, quality of life after treatment and new interventional procedures and implementation of these procedures in routine practice (embolization in patients with symptomatic uterine fibroids).
  • Gastrointestinal: Prof. J. Stoker, MD, PhD
    esearch is aimed at development and evaluation of imaging techniques for gastro-intestinal diseases, especially colorectal cancer, Crohn’s disease, acute abdomen and focal and diffuse liver diseases. Improving accuracy and reducing burden are themes common to the research in this field.
  • Neurovascular: Prof. C.B.L.M. Majoie, MD, PhD
    Research is aimed at development and evaluation of imaging techniques and image guided interventions of neurovascular disorders such as intracranial aneurysms and stroke. Further research includes innovations in MR imaging of neurodegenerative disorders and neuro-oncology.
  • Neuropsychiatric: Prof. L. Reneman, MD, PhD
    To develop and apply state of the art imaging techniques to investigate effects of drugs on the human brain and its development. Long-term ambitions and goals are to investigate the neuropharmacological basis for psychiatric diseases in childhood and adolescence, and, ultimately, to predict treatment outcome – using a multidisciplinary approach.
  • Novel MRI techniques: A.J. Nederveen, PhD
    Research is aimed at designing and validating new MRI methods, mainly in the field of neurovascular, muscular and abdominal imaging.

Other research
Further research is concentrated on:

  • Advanced medical image processing: F.M. Vos, PhD
    Research is focused on advanced medical image processing for virtual colonoscopy, diffusion tensor imaging and carpal bone movement.
  • Validation of imaging techniques in children: Project leader: R.R. van Rijn, MD, PhD
    Research is focused on the validation of imaging techniques in children.
  • Image analysis from 3D and 4D medical images: G.J. Streekstra, PhD
    Research is devoted to development of new image formation methods and associated image analysis from 3D and 4D medical images.
  • MRI in rheumatoid and metabolic diseases: M. Maas, MD, PhD
    Research is focused on MRI in rheumatoid diseases and metabolic disorders, such as association between MRI-findings and disease activity in knees of Juvenile Idiopathic Arthritis (JIA) patients.
  • Image acquisition and quantitative image analyses: Henk Marquering, PhD
    Within this topic research is performed on the image acquisition and quantitative image analyses of the cardiovascular system, and the neuro-vascular system in particular.
  • Gastrointestinal imaging: evidence based radiology: Shandra Bipat, PhD
    Evaluation of imaging techniques for diagnosis and staging of gastro-intestinal diseases by analyzing primary findings and by summarizing the evidence (systematic reviews and meta-analysis). The results of these reviews and meta-analyses serve as the cornerstone for the development of guidelines.