Introduction

Cardiovascular disease is a major public health issue: more than 45,000 people die of its effects each year in the Netherlands alone. Research at AMC focuses on predicting and preventing these conditions, as well as on repairing heart damage.

Understanding the myocardial function
The fundamental research on the heart is brought together in the AMC Heart Failure Research Center. The centers unifying aim is to understand the myocardial function in the broadest sense of the word in order to make inroads into clinical applications. The research groups bundled in the HFRC focus primarily on the clinical domains of congenital heart defects, cardiac arrhythmias and heart failure.


Genetic mutations at the root of heart failure
The Durrer Center for Cardiogenetic Research has been housed at AMC since 2008. This institute manages a national database of blood samples collected from patients with congenital heart and vascular conditions that is used to track down the genetic mutations responsible for these conditions. A greater understanding of this factor should make it possible to identify vulnerable patients at an earlier stage, and thus, reduce their chances of dying a sudden death.

Principal Investigators in the field of Cardiovascular Diseases can be found under the heading of Who is Who in Research.

Amsterdam Cardiovascular Sciences

The AMC researchers on cardiovasculair sciences collaborate with their VUmc colleagues within the research institute Amsterdam Cardiovascular Sciences. Amsterdam Cardiovascular Sciences is one of the eight AMC – VUmc research institutes. These institutes bring together opinion leading academic research in the field of Health & Life Sciences developed in the Amsterdam Region.