• Principal Investigator
  • Male

Dr. R. Coronel MD PhD

Position:
Main activities: Research, Teaching
Specialisation:
foto R. Coronel is one of the AMC Principal Investigators
Focus of research:

 see www.ruben-coronel.nl

AMC themes: Cardiovascular Diseases
Departments: Cardiology
Baartscheer A, Schumacher CA, Wüst RCI, Fiolet JWT, Stienen GJM, Coronel R, Zuurbier CJ, Empagliflozin decreases myocardial cytoplasmic Na(+) through inhibition of the cardiac Na(+)/H(+) exchanger in rats and rabbits. DIABETOLOGIA 2017;60 (3):568-573 [PubMed]
Boukens BJ, Meijborg VMF, Belterman CN, Opthof T, Janse MJ, Schuessler RB, Coronel R, Efimov IR, Local transmural action potential gradients are absent in the isolated, intact dog heart but present in the corresponding coronary-perfused wedge. PHYSIOL REP 2017;5 (10):e13251 [PubMed]
Coronel R, Restitution slope is determined by the steady state action potential duration: law and disorder. CARDIOVASC RES 2017;113 (7):705-707 [PubMed]
Coronel R, The pro- or antiarrhythmic actions of polyunsaturated fatty acids and of cholesterol. PHARMACOL THERAPEUT 2017;176:40-47 [PubMed]
Meijborg VMF, Belterman CNW, de Bakker JMT, Coronel R, Conrath CE, Mechano-electric coupling, heterogeneity in repolarization and the electrocardiographic T-wave. PROG BIOPHYS MOL BIO 2017;-:- [PubMed]
Opthof T, Remme CA, Jorge E, Noriega F, Wiegerinck RF, Tasiam A, Beekman L, Alvarez-Garcia J, Munoz-Guijosa C, Coronel R, Cinca J, Cardiac activation-repolarization patterns and ion channel expression mapping in intact isolated normal human hearts. HEART RHYTHM 2017;14 (2):265-272 [PubMed]
Smit NW, Cócera Ortega L, Végh AMD, Meijborg VMF, Smits AM, Klerk M, Tijsen AJM, Tan HL, Goumans MJHT, Boink GJJ, Coronel R, Human Cardiomyocyte Progenitor Cells in Co-culture with Rat Cardiomyocytes Form a Pro-arrhythmic Substrate: Evidence for Two Different Arrhythmogenic Mechanisms. FRONT PHYSIOL 2017;8:797 [PubMed]
Smit NW, ten Sande JN , Parvizi M, van Amersfoorth SCM, Plantinga JA, van Spreuwel-Goossens CAFM, van Dongen EMWM, van Dessel PFHM, Kluijtmans SGJM, Meijborg VMF, de Bakker JMT, Harmsen MC, Coronel R, Recombinant human collagen-based microspheres mitigate cardiac conduction slowing induced by adipose tissue-derived stromal cells. PLOS ONE 2017;12 (8):e0183481 [PubMed]
Tadros R, Coronel R, Bezzina CR, Dissecting the Genetic Basis of the ECG as a Means of Understanding Mechanisms of Arrhythmia. CIRC-CARDIOVASC GENE 2017;10 (4):UNSP e001858 [PubMed]
ten Sande JN. Modulators of ventricular arrhythmias in structurally normal and abnormal hearts. S.l.: s.n.; 2017. 175p. ISBN 978-90-77595-17-6 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): de BJMT, Wilde AAM; copromotor(s): van Dessel PFHM, Coronel R)
ten Sande JN , Smit NW, Parvizi M, van Amersfoorth SCM, Plantinga JA, van Dessel PFHM, de Bakker JMT, Harmsen MC, Coronel R, Differential Mechanisms of Myocardial Conduction Slowing by Adipose Tissue-Derived Stromal Cells Derived From Different Species. STEM CELL TRANSL MED 2017;6 (1):22-30 [PubMed]
Veerman CC, Podliesna S, Tadros R, Lodder EM, Mengarelli I, de Jonge B, Beekman L, Barc J, Wilders R, Wilde AAM, Boukens BJ, Coronel R, Verkerk AO, Remme CA, Bezzina CR, The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity. CIRC RES 2017;121 (5):537-548 [PubMed]
Veerman CC, Wilders R, Wilde AA, Coronel R, Remme CA, Verkerk AO, Bezzina CR, Response by Veerman et al to Letter Regarding Article, "The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity". CIRC RES 2017;121 (5):E21 [PubMed]
Baartscheer A, Veldkamp MW, Coronel R, Letter by Baartscheer et al Regarding Editorial, "Matter of Fat: Are Lipids Antiarrhythmic?". CIRC-ARRHYTHMIA ELEC 2016;9 (3):e003933 [PubMed]
Boukens BJ, Coronel R, Christoffels VM, Embryonic development of the right ventricular outflow tract and arrhythmias. HEART RHYTHM 2016;13 (2):616-622 [PubMed]
Boukens BJ, Walton R, Meijborg VM, Coronel R, Transmural electrophysiological heterogeneity, the T-wave and ventricular arrhythmias. PROG BIOPHYS MOL BIO 2016;122 (3):202-214 [PubMed]
Gouadon E, Moore-Morris T, Smit NW, Chatenoud L, Coronel R, Harding SE, Jourdon P, Lambert V, Rucker-Martin C, Pucéat M, Concise Review: Pluripotent Stem Cell-Derived Cardiac Cells, A Promising Cell Source for Therapy of Heart Failure: Where Do We Stand?. STEM CELLS 2016;34 (1):34-43 [PubMed]
Hakimzadeh N, van Lier MGJTB, van Horssen P, Daal M, Ly DH, Belterman C, Coronel R, Spaan JAE, Siebes M, Selective subepicardial localization of monocyte subsets in response to progressive coronary artery constriction. AM J PHYSIOL-HEART C 2016;311 (1):H239-H250 [PubMed]
Hill YR, Child N, Hanson B, Wallman M, Coronel R, Plank G, Rinaldi CA, Gill J, Smith NP, Taggart P, Bishop MJ, Investigating a Novel Activation-Repolarisation Time Metric to Predict Localised Vulnerability to Reentry Using Computational Modelling. PLOS ONE 2016;11 (3):e0149342 [PubMed]
Meijborg VMF, Potse M, Conrath CE, Belterman CNW, de Bakker JMT, Coronel R, Reduced Sodium Current in the Lateral Ventricular Wall Induces Inferolateral J-Waves. FRONT PHYSIOL 2016;7:365 [PubMed]
Oosterhoff P, Meijborg VMF, van Dam PM, van Dessel PFHM, Belterman CNW, Streekstra GJ, de Bakker JMT, Coronel R, Oostendorp TF, Experimental Validation of Noninvasive Epicardial and Endocardial Activation Imaging. CIRC-ARRHYTHMIA ELEC 2016;9 (8):e004104 [PubMed]
Opthof T, Janse MJ, Meijborg VMF, Cinca J, Rosen MR, Coronel R, Dispersion in ventricular repolarization in the human, canine and porcine heart. PROG BIOPHYS MOL BIO 2016;120 (1-3):222-235 [PubMed]
Qiu XS, Chauveau S, Anyukhovsky EP, Rahim T, Jiang YP, Harleton E, Feinmark SJ, Lin RZ, Coronel R, Janse MJ, Opthof T, Rosen TS, Cohen IS, Rosen MR, Increased Late Sodium Current Contributes to the Electrophysiological Effects of Chronic, but Not Acute, Dofetilide Administration. CIRC-ARRHYTHMIA ELEC 2016;9 (4):e003655 [PubMed]
Baartscheer A, Schumacher CA, Wekker V, Verkerk AO, Veldkamp MW, van Oort RJ, Elzenaar I, Ottenhoff R, van Roomen C, Aerts H, Coronel R, Dyscholesterolemia Protects Against Ischemia-Induced Ventricular Arrhythmias. CIRC-ARRHYTHMIA ELEC 2015;8 (6):1481-1490 [PubMed]
Child N, Bishop MJ, Hanson B, Coronel R, Opthof T, Boukens BJ, Walton RD, Efimov IR, Bostock J, Hill Y, Rinaldi CA, Razavi R, Gill J, Taggart P, An activation-repolarization time metric to predict localized regions of high susceptibility to reentry. HEART RHYTHM 2015;12 (7):1644-1653 [PubMed]
Doshi AN, Walton RD, Krul SP, de Groot JR, Bernus O, Efimov IR, Boukens BJ, Coronel R, Feasibility of a semi-automated method for cardiac conduction velocity analysis of high-resolution activation maps. COMPUT BIOL MED 2015;65:177-183 [PubMed]
Hoogendijk MG, Coronel R, J-wave syndrome(s). TRENDS CARDIOVAS MED 2015;25 (1):22-23 [PubMed]
Krul SPJ, Berger WR, Smit NW, van Amersfoorth SCM, Driessen AHG , van Boven WJ, Fiolet JWT, van Ginneken ACG, van der Wal AC, de Bakker JMT, Coronel R, de Groot JR, Atrial Fibrosis and Conduction Slowing in the Left Atrial Appendage of Patients Undergoing Thoracoscopic Surgical Pulmonary Vein Isolation for Atrial Fibrillation. CIRC-ARRHYTHMIA ELEC 2015;8 (2):288-295 [PubMed]
Krul SPJ, Berger WR, Smit NW, van Amersfoorth SCM, Driessen AHG , van Boven WJ, Fiolet JWT, van Ginneken ACG, van der Wal AC, de Bakker JMT, Coronel R, de Groot JR, Response to letter regarding article, "atrial fibrosis and conduction slowing in the left atrial appendage of patients undergoing thoracoscopic surgical pulmonary vein isolation for atrial fibrillation". CIRC-ARRHYTHMIA ELEC 2015;8 (4):997 [PubMed]
Meijborg VMF. The T wave: Physiology and pathophysiology. S.l.: s.n.; 2015. 168p. ISBN 978-94-6169-710-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Wilde AAM, de BJMT; copromotor(s): Coronel R, Conrath CE)
Meijborg VMF, Chauveau S, Janse MJ, Anyukhovsky EP, Danilo PR Jr, Rosen MR, Opthof T, Coronel R, Interventricular dispersion in repolarization causes bifid T waves in dogs with dofetilide-induced long QT syndrome. HEART RHYTHM 2015;12 (6):1343-1351 [PubMed]
Opthof T, Meijborg VMF, Belterman CNW, Coronel R, Synchronization of repolarization by mechano-electrical coupling in the porcine heart. CARDIOVASC RES 2015;108 (1):181-187 [PubMed]
ten Sande JN , Coronel R, Conrath CE, Driessen AHG , de Groot JR, Tan HL, Nademanee K, Wilde AAM, de Bakker JMT, van Dessel PFHM, ST-Segment Elevation and Fractionated Electrograms in Brugada Syndrome Patients Arise From the Same Structurally Abnormal Subepicardial RVOT Area but Have a Different Mechanism. CIRC-ARRHYTHMIA ELEC 2015;8 (6):1382-1392 [PubMed]
Boukens BJ, Rivaud MR, Rentschler S, Coronel R, Misinterpretation of the mouse ECG: 'musing the waves of Mus musculus'. J PHYSIOL-LONDON 2014;592 (Part 21):4613-4626 [PubMed]
Hakimzadeh N, van Horssen P, van Lier MGJTB, van den Wijngaard JPHM, Belterman C, Coronel R, Piek JJ, Verberne HJ, Spaan JAE, Siebes M, Detection and quantification methods of monocyte homing in coronary vasculature with an imaging cryomicrotome. J MOL CELL CARDIOL 2014;76:196-204 [PubMed]
Hanson B, Child N, van Duijvenboden S, Orini M, Chen Z, Coronel R, Rinaldi CA, Gill JS, Gill JS, Taggart P, Oscillatory behavior of ventricular action potential duration in heart failure patients at respiratory rate and low frequency. FRONT PHYSIOL 2014;5:414 [PubMed]
Krul SPJ, Meijborg VMF, Berger WR, Linnenbank AC, Driessen AHG , van Boven WJ, Wilde AAM, de Bakker JM, Coronel R, de Groot JR, Disparate response of high-frequency ganglionic plexus stimulation on sinus node function and atrial propagation in patients with atrial fibrillation. HEART RHYTHM 2014;11 (10):1743-1751 [PubMed]
Linnenbank AC, de Bakker JMT, Coronel R, How to measure propagation velocity in cardiac tissue: a simulation study. FRONT PHYSIOL 2014;5:267 [PubMed]
Marsman RFJ, Bezzina CR, Freiberg F, Verkerk AO, Adriaens ME, Podliesna S, Chen C, Purfürst B, Spallek B, Koopmann TT, Baczko I, dos Remedios CG, George AL Jr, Bishopric NH, Lodder EM, de Bakker JMT, Fischer R, Coronel R, Wilde AAM, Gotthardt M, Remme CA, Coxsackie and Adenovirus Receptor Is a Modifier of Cardiac Conduction and Arrhythmia Vulnerability in the Setting of Myocardial Ischemia. J AM COLL CARDIOL 2014;63 (6):549-559 [PubMed]
Meijborg VMF, Conrath CE, Opthof T, Belterman CNW, de Bakker JMT, Coronel R, Electrocardiographic T wave and its relation with ventricular repolarization along major anatomical axes. CIRC-ARRHYTHMIA ELEC 2014;7 (3):524-531 [PubMed]
Smit NW, Coronel R, Stem cells can form gap junctions with cardiac myocytes and exert pro-arrhythmic effects. FRONT PHYSIOL 2014;5:419 [PubMed]
Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bézieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R, Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. NAT GENET 2013;45 (9):1044-1049 [PubMed]
Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bézieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R, Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. NAT GENET 2013;45 (11):1409 [PubMed]
Boukens BJ, Hoogendijk MG, Verkerk AO, Linnenbank A, van Dam P, Remme CA, Fiolet JW, Opthof T, Christoffels VM, Coronel R, Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration. CARDIOVASC RES 2013;97 (1):182-191 [PubMed]
Boukens BJ, Sylva M, de Gier-de Vries C, Remme CA, Bezzina CR, Christoffels VM, Coronel R, Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract. CIRC RES 2013;113 (2):137-141 [PubMed]
Coronel R, Wilders R, Verkerk AO, Wiegerinck RF, Benoist D, Bernus O, Electrophysiological changes in heart failure and their implications for arrhythmogenesis. BBA-MOL BASIS DIS 2013;1832 (12):2432-2441 [PubMed]
Geuzebroek GSC. Modulation of atrial fibrillation. s.l.: s.n.; 2013. 175p. ISBN 978949461822659 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): de Bakker JMT; copromotor(s): Coronel R, Veldkamp MW)
Hoogendijk MG. Pathophysiological mechanisms of arrhythmogenic right ventricular disorders. s.l.: s.n.; 2013. 197p. ISBN 9789461822666 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): de BJMT; copromotor(s): Coronel R)
Hoogendijk MG, Coronel R, The J-wave conundrum: early repolarization and Brugada syndrome. HEART RHYTHM 2013;10 (4):540-541 [PubMed]
Hoogendijk MG, Potse M, Coronel R, Critical appraisal of the mechanism underlying J waves. J ELECTROCARDIOL 2013;46 (5):390-394 [PubMed]
Boukens BJD. Electrophysiological patterning of the heart. s.l.: s.n.; 2012. 167p. ISBN 9789461909978 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Christoffels VM; copromotor(s): Coronel R)
Coronel R, Janse MJ, Opthof T, Wilde AAM, Taggart P, Reply To the Editor-Postrepolarization Refractoriness in Acute Ischemia and After Antiarrhythmic Drug Administration. HEART RHYTHM 2012;9 (5):E14 [PubMed]
Coronel R, Janse MJ, Opthof T, Wilde AA, Taggart P, Postrepolarization refractoriness in acute ischemia and after antiarrhythmic drug administration: Action potential duration is not always an index of the refractory period. HEART RHYTHM 2012;9 (6):977-982 [PubMed]
den Ruijter HM, Verkerk AO, Schumacher CA, Houten SM, Belterman CNW, Baartscheer A, Brouwer IA, van Bilsen M, de Roos B, Coronel R, A Diet Rich in Unsaturated Fatty Acids Prevents Progression Toward Heart Failure in a Rabbit Model of Pressure and Volume Overload. CIRC-HEART FAIL 2012;5 (3):376-384 [PubMed]
Geuzebroek GSC, van Amersfoorth SCM, Hoogendijk MG, Kelder JC, van Hemel NM, de Bakker JMT, Coronel R, Increased amount of atrial fibrosis in patients with atrial fibrillation secondary to mitral valve disease. J THORAC CARDIOV SUR 2012;144 (2):327-333 [PubMed]
Hanson B, Gill J, Western D, Gilbey MP, Bostock J, Boyett MR, Zhang H, Coronel R, Taggart P, Cyclical modulation of human ventricular repolarization by respiration. FRONT PHYSIOL 2012;3:UNSP 379 [PubMed]
Hoogendijk MG, Potse M, Coronel R, Early repolarization patterns: The good, the bad, and the ugly?. HEART RHYTHM 2012;9 (2):230-231 [PubMed]
Hoogendijk MG, Schumacher CA, Belterman CNW, Boukens BJ, Berdowski J, de Bakker JMT, Koster RW, Coronel R, Ventricular fibrillation hampers the restoration of creatine-phosphate levels during simulated cardiopulmonary resuscitations. EUROPACE 2012;14 (10):1518-1523 [PubMed]
Janse MJ, Coronel R, Opthof T, Sosunov EA, Anyukhovsky EP, Rosen MR, Repolarization gradients in the intact heart: Transmural or apico-basal?. PROG BIOPHYS MOL BIO 2012;109 (1-2):6-15 [PubMed]
Opthof T, Janse MJ, Kléber AG, Wellens HJJ, Wilde AAM, Coronel R, The works of Dirk Durrer (1918-1984). NETH HEART J 2012;20 (10):430-433 [PubMed]
Opthof T, Sutton P, Coronel R, Wright S, Kallis P, Taggart P, The association of abnormal ventricular wall motion and increased dispersion of repolarization in humans is independent of the presence of myocardial infarction. FRONT PHYSIOL 2012;3:UNSP 235 [PubMed]
Spaan JAE, Coronel R, Fifty years of publishing in biomedical engineering: reflections after 7-year editorship. MED BIOL ENG COMPUT 2012;50 (12):1183-1186 [PubMed]
van Borren MMGJ, den Ruijter HM, Baartscheer A, Ravesloot JH, Coronel R, Verkerk AO, Dietary omega-3 polyunsaturated fatty acids suppress NHE-1 upregulation in a rabbit model of volume- and pressure-overload. FRONT PHYSIOL 2012;3:UNSP 76 [PubMed]
Aanhaanen WTJ, Boukens BJD, Sizarov A, Wakker V, de Gier-de Vries C, van Ginneken AC, Moorman AFM, Coronel R, Christoffels VM, Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice. J CLIN INVEST 2011;121 (2):534-544 [PubMed]
Baartscheer A, Schumacher CA, Coronel R, Fiolet JWT, The driving force of the Na+/Ca2+-exchanger during metabolic inhibition. FRONT PHYSIOL 2011;2:10 [PubMed]
Coronel R, Spaan JA, Voigt HF, Engineering and ethical constraints. MED BIOL ENG COMPUT 2011;49 (1):1-2 [PubMed]
Coronel R, Trayanova N, Jie X, Janse MJ. Stretch-induced arrhythmias in ischaemia in: Kohl P, Sachs F, Franz MR, editors. Cardiac mechano-electric coupling and arrhythmias. New York: Oxford University Press; 2011., p. 352-358
den Ruijter HM, Franssen R, Verkerk AO, van Wijk DF, Vaessen SF, Holleboom AG, Levels JH, Opthof T, Sungnoon R, Stroes ES, Kuivenhoven JA, Coronel R, Reconstituted High-Density Lipoprotein Shortens Cardiac Repolarization. J AM COLL CARDIOL 2011;58 (1):40-44 [PubMed]
Fabritz L, Hoogendijk MG, Scicluna BP, van Amersfoorth SCM, Fortmueller L, Wolf S, Laakmann S, Kreienkamp N, Piccini I, Breithardt G, Noppinger PR, Witt H, Ebnet K, Wichter T, Levkau B, Franke WW, Pieperhoff S, de Bakker JMT, Coronel R, Kirchhof P, Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice. J AM COLL CARDIOL 2011;57 (6):740-750 [PubMed]
Hoogendijk MG, Potse M, Vinet A, de Bakker JMT, Coronel R, ST segment elevation by current-to-load mismatch: an experimental and computational study. HEART RHYTHM 2011;8 (1):111-118 [PubMed]
Janse MJ, Coronel R. Volume and pressure overload and ventricular arrhythmogenesis in: Kohl P, Sachs F, Franz MR, editors. Cardiac mechano-electric coupling and arrhythmias. New York: Oxford University Press; 2011., p. 313-317
Janse MJ, Coronel R, Opthof T, Counterpoint: M cells do not have a functional role in the ventricular myocardium of the intact heart. HEART RHYTHM 2011;8 (6):934-937 [PubMed]
Janse MJ, Coronel R, Opthof T, Rebuttal to M cells are present in the ventricular myocardium. Counterpoint. HEART RHYTHM 2011;8 (7):1100 [PubMed]
Oostendorp TF, van Dessel PFHM, Coronel R, Belterman C, Linnenbank AC, van Schie IH, van Oosterom A, Oosterhoff P, van Dam PM, de Bakker JMT, Noninvasive detection of epicardial and endocardial activity of the heart. NETH HEART J 2011;19 (11):488-491 [PubMed]
Opthof T, Janse MJ, Coronel R, Letter by Opthof et al regarding article, "Prolonged Tpeak to tend interval on the resting electrocardiogram is associated with increased risk of sudden cardiac death". CIRC-ARRHYTHMIA ELEC 2011;4 (6):e87; author reply e88 [PubMed]
Scicluna BP, Tanck MWT, Remme CA, Beekman L, Coronel R, Wilde AAM, Bezzina CR, Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouse. J MOL CELL CARDIOL 2011;50 (3):380-389 [PubMed]
Verkerk AO, Baartscheer A, de Groot JR, Wilders R, Coronel R, Etiology-dependency of ionic remodeling in cardiomyopathic rabbits. INT J CARDIOL 2011;148 (2):154-160 [PubMed]
Coronel R, Mind the gap: Engineering resilient gap junctions. HEART RHYTHM 2010;7 (10):1499-1500 [PubMed]
Coronel R, Dun W, Boyden PA, de Bakker JMT. Arrhythmia mechanisms in ischemia and infarction in: Billman GE, editors. Novel Therapeutic Targets for Antiarrhythmic Drugs. New Jersey: John Wiley & Sons, Inc.; 2010., p. 101-153
Coronel R, Langerveld J, Boersma LVA, Wever EFD, Bon L, van Dessel PFHM, Linnenbank AC, van Gilst WH, Ernst SMPG, Opthof T, van Hemel NM, Left atrial pressure reduction for mitral stenosis reverses left atrial direction-dependent conduction abnormalities. CARDIOVASC RES 2010;85 (4):711-718 [PubMed]
Coronel R, Lau DH, Sosunov EA, Janse MJ, Danilo P Jr, Anyukhovsky EP, Wilms-Schopman FJG, Opthof T, Shlapakova IN, Ozgen N, Prestia K, Kryukova Y, Cohen IS, Robinson RB, Rosen MR, Cardiac Expression of Skeletal Muscle Sodium Channels Increases Longitudinal Conduction Velocity in the Canine One Week Myocardial Infarction. HEART RHYTHM 2010;7 (8):1104-1110 [PubMed]
den Ruijter HM, Verkerk AO, Coronel R, Incorporated fish oil fatty acids prevent action potential shortening induced by circulating fish oil fatty acids. FRONT PHYSIOL 2010;1 (149):1-5
Hoogendijk MG, Opthof T, Postema PG, Wilde AAM, de Bakker JMT, Coronel R, The Brugada ECG Pattern A Marker of Channelopathy, Structural Heart Disease, or Neither? Toward a Unifying Mechanism of the Brugada Syndrome. CIRC-ARRHYTHMIA ELEC 2010;3 (3):283-290 [PubMed]
Hoogendijk MG, Potse M, Linnenbank AC, Verkerk AO, den Ruijter HM, van Amersfoorth SCM, Klaver EC, Beekman L, Bezzina CR, Postema PG, Tan HL, Reimer AG, van der Wal AC, ten Harkel ADJ, Dalinghaus M, Vinet A, Wilde AAM, de Bakker JMT, Coronel R, Mechanism of right precordial ST-segment elevation in structural heart disease: Excitation failure by current-to-load mismatch. HEART RHYTHM 2010;7 (2):238-248 [PubMed]
van den Wijngaard JPHM, van Horssen P, ter Wee R, Coronel R, de Bakker JM, de Jonge N, Siebes M, Spaan JAE, Organization and collateralization of a subendocardial plexus in end-stage human heart failure. AM J PHYSIOL-HEART C 2010;298 (1):H158-H162 [PubMed]
Boukens BJD, Christoffels VM, Coronel R, Moorman AFM, Developmental basis for electrophysiological heterogeneity in the ventricular and outflow tract myocardium as a substrate for life-threatening ventricular arrhythmias. CIRC RES 2009;104 (1):19-31 [PubMed]
Coronel R, Complexity and the interpretation of results. HEART RHYTHM 2009;6 (4):528-529 [PubMed]
Coronel R, Wilms-Schopman FJG, Opthof T, Janse MJ, Dispersion of repolarization and arrhythmogenesis. HEART RHYTHM 2009;6 (4):537-543 [PubMed]
den Ruijter HM, Coronel R, The response to fish oil in patients with heart disease depends on the predominant arrhythmia mechanism. CARDIOVASC DRUG THER 2009;23 (4):333-4; author reply 335-6 [PubMed]
Opthof T, Coronel R, Janse MJ, Is there a significant transmural gradient in repolarization time in the intact heart?: Repolarization Gradients in the Intact Heart. CIRC-ARRHYTHMIA ELEC 2009;2 (1):89-96 [PubMed]
Potse M, Vinet A, Opthof T, Coronel R, Validation of a simple model for the morphology of the T wave in unipolar electrograms. AM J PHYSIOL-HEART C 2009;297 (2):H792-H801 [PubMed]
Verkerk AO, den Ruijter HM, Bourier J, Boukens BJ, Brouwer IA, Wilders R, Coronel R, Dietary fish oil reduces pacemaker current and heart rate in rabbit. HEART RHYTHM 2009;6 (10):1485-1492 [PubMed]
Verkerk AO, den Ruijter HM, de Jonge N, Coronel R, Fish oil curtails the human action potential dome in a heterogeneous manner: Implication for arrhythmogenesis. INT J CARDIOL 2009;132 (1):138-140 [PubMed]
Wiegerinck RF, de Bakker JMT, Opthof T, de Jonge N, Kirkels H, Wilms-Schopman FJG, Coronel R, The effect of enhanced gap junctional conductance on ventricular conduction in explanted hearts from patients with heart failure. BASIC RES CARDIOL 2009;104 (3):321-332 [PubMed]
Baartscheer A, Hardziyenka M, Schumacher CA, Belterman CNW, van Borren MMGJ, Verkerk AO, Coronel R, Fiolet JWT, Chronic inhibition of the Na(+)/H(+)- exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling. BRIT J PHARMACOL 2008;154 (6):1266-1275 [PubMed]
Coronel R. Pathofysiologische grondslagen van ritmestoornissen in: van der Wall EE, Van de Werf F, Zijlstra F, editors. Cardiologie. Houten: Bohn Stafleu van Loghum; 2008., p. 251-259
den Ruijter HM, Berecki G, Verkerk AO, Bakker D, Baartscheer A, Schumacher CA, Belterman CNW, de Jonge N, Fiolet JWT, Brouwer IA, Coronel R, Acute administration of fish oil inhibits triggered activity in isolated myocytes from rabbits and patients with heart failure. CIRCULATION 2008;117 (4):536-544 [PubMed]
den Ruijter HM, Berecki G, Verkerk AO, Bakker D, Baartscheer A, Schumacher CA, Belterman CNW, Fiolet JWT, Coronel R, de Jonge N, Brouwer IA, Response to letter regarding article "Acute Administration of Fish Oil Inhibits Triggered Activity in Isolated Myocytes From Rabbits and Patients With Heart Failure". CIRCULATION 2008;118 (3):E70
Dullemeijer C, Zock PL, Coronel R, den Ruijter HM, Katan MB, Brummer RJM, Kok FJ, Beekman J, Brouwer IA, Differences in fatty acid composition between cerebral brain lobes in juvenile pigs after fish oil feeding. BRIT J NUTR 2008;100 (4):794-800 [PubMed]
Jie X, Rodríguez B, de Groot JR, Coronel R, Trayanova N, Reentry in survived subepicardium coupled to depolarized and inexcitable midmyocardium: insights into arrhythmogenesis in ischemia phase 1B. HEART RHYTHM 2008;5 (7):1036-1044 [PubMed]
Postema PG, van Dessel PFHM, de Bakker JMT, Dekker LRC, Linnenbank AC, Hoogendijk MG, Coronel R, Tijssen JGP, Wilde AAM, Tan HL, Slow and discontinuous conduction conspire in Brugada syndrome: a right ventricular mapping and stimulation study. CIRC-ARRHYTHMIA ELEC 2008;1 (5):379-386 [PubMed]
Wiegerinck RF, van Veen TAB, Befterman CN, Schumacher CA, Noorman M, de Bakker JMT, Coronel R, Transmural dispersion of refractoriness and conduction velocity is associated with heterogeneously reduced connexin43 in a rabbit model of heart failure. HEART RHYTHM 2008;5 (8):1178-1185 [PubMed]
Wilde AAM, Coronel R, The complexity of genotype-phenotype relations associated with loss-of-function sodium channel mutations and the role of in silico studies. AM J PHYSIOL-HEART C 2008;295 (1):H8-H9 [PubMed]
Berecki G, den Ruijter HM, Verkerk AO, Schumacher CA, Baartscheer A, Bakker D, Boukens BJ, van Ginneken ACG, Fiolet JWT, Opthof T, Coronel R, Dietary fish oil reduces the incidence of triggered arrhythmias in pig ventricular myocytes. HEART RHYTHM 2007;4 (11):1452-1460 [PubMed]
Coronel R, Myths, metaphors, and mathematical models. HEART RHYTHM 2007;4 (8):1046-1047 [PubMed]
Coronel R, de Bakker JM, Janse MJ, Opthof T, Response to comments of Dr. Yue. Letter to the editor. HEART RHYTHM 2007;4 (1):121 [PubMed]
Coronel R, Opthof T, Plotnikov AN, Wilms-Schopman FJG, Shlapakova IN, Danilo P Jr, Sosunov EA, Anyukhovsky EP, Janse MJ, Rosen MR, Long-term cardiac memory in canine heart is associated with the evolution of a transmural repolarization gradient. CARDIOVASC RES 2007;74 (3):416-425 [PubMed]
Coronel R, Wilms-Schopman FJG, den Ruijter HM, Belterman CN, Schumacher CA, Opthof T, Hovenier R, Lemmens AG, Terpstra AHM, Katan MB, Zock P, Dietary n-3 fatty acids promote arrhythmias during acute regional myocardial ischemia in isolated pig hearts. CARDIOVASC RES 2007;73 (2):386-394 [PubMed]
den Ruijter HM. Pro- and antiarrhythmic properties of fish oil. s.l.: s.n.; 2007. 197p. ISBN 9789090220611 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): de Bakker JMT; copromotor(s): Coronel R)
den Ruijter HM, Berecki G, Opthof T, Verkerk AO, Zock PL, Coronel R, Pro- and antiarrhythmic properties of a diet rich in fish oil. CARDIOVASC RES 2007;73 (2):316-325 [PubMed]
Linnenbank AC, van Oosterom A, Oostendorp TF, van Dessel PFHM, van Rossum AC, Coronel R, Tan HL, de Bakker JMT. Relative contribution of heart regions to the precordial ECG - an inverse computational approach in: Jarm T, Kramar P, Zupanic A, editors. 11th Mediterranean Conference on Medical and Biomedical Engineering and Computing 2007. S.l.: Springer; 2007., p. 42-45
Opthof T, Coronel R, Janse MJ, Rosen MR, A wedge is not a heart - Response. HEART RHYTHM 2007;4 (8):1116-1119 [PubMed]
Opthof T, Coronel R, Wilms-Schopman FJG, Plotnikov AN, Shlapakova IN, Danilo P Jr, Rosen MR, Janse MJ, Dispersion of repolarization in canine ventricle and the electrocardiographic T wave: Tp-e interval does not reflect transmural dispersion. HEART RHYTHM 2007;4 (3):341-348 [PubMed]
Potse M, Coronel R, Falcao S, LeBlanc AR, Vinet A, The effect of lesion size and tissue remodeling on ST deviation in partial-thickness ischemia. HEART RHYTHM 2007;4 (2):200-206 [PubMed]
Potse M, Coronel R, LeBlanc AR, Vinet A, Modeling transport of interstitial potassium in regional myocardial ischemia: effect on the injury current. CONF PROC IEEE ENG MED BIOL SOC 2007;2007:6331-6334 [PubMed]
Potse M, Coronel R, LeBlanc AR, Vinet A, The role of extracellular potassium transport in computer models of the ischemic zone. MED BIOL ENG COMPUT 2007;45 (12):1187-1199 [PubMed]
Potse M, Coronel R, Opthof T, Vinet A, Simulating T-wave parameters of local extracellular electrograms with a whole-heart bidomain reaction-diffusion model: Size matters!. CONF PROC IEEE ENG MED BIOL SOC 2007;2007:6645-6648 [PubMed]
Potse M, Coronel R, Opthof T, Vinet A, The positive T wave. ANADOLU KARDIYOL DER 2007;7 (Suppl. 1):164-167 [PubMed]
Spaan JAE, Coronel R, de Bakker JMT, Zaza A, editors, Biopacemaking. Berlin-Heidelberg: Springer Verlag; 2007. -p.
Verkerk AO, van Borren MMGJ, Peters RJG, Broekhuis E, Lam KY, Coronel R, de Bakker JMT, Tan HL, Wilders R, Single cells isolated from human sinoatrial node: action potentials and numerical reconstruction of pacemaker current. CONF PROC IEEE ENG MED BIOL SOC 2007;2007:904-907 [PubMed]
Verkerk AO, Wilders R, van Borren MMGJ, Peters RJG, Broekhuis E, Lam K, Coronel R, de Bakker JMT, Tan HL, Pacemaker current (I(f)) in the human sinoatrial node. EUR HEART J 2007;28 (20):2472-2478 [PubMed]
Coronel R, Berecki G, Opthof T, Why the Brugada syndrome is not yet a disease: syndromes, diseases, and genetic causality. CARDIOVASC RES 2006;72 (3):361-363 [PubMed]
Coronel R, Casini S, Koopmann TT, Verkerk AO, de Groot JR, Bezzina CR, Veldkamp MW, Linnenbank AC, Tan HL, Wilde AAM, de Bakker JMT, Wilms-Schopman FJG, Bhuiyan Z, van der Wal AC, Brugada P, Letters regarding article by Coronel et al, "Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: A combined electrophysiological, genetic, histopathologic, and computational study" - Response. CIRCULATION 2006;113 (16):E726-E727
Coronel R, de Bakker JMT, Wilms-Schopman FJG, Opthof T, Linnenbank AC, Belterman CN, Janse MJ, Monophasic action potentials and activation recovery intervals as measures of ventricular action potential duration: experimental evidence to resolve some controversies. HEART RHYTHM 2006;3 (9):1043-1050 [PubMed]
den Ruijter HM, Verkerk AO, Berecki G, Bakker D, van Ginneken ACG, Coronel R, Dietary fish oil reduces the occurrence of early afterdepolarizations in pig ventricular myocytes. J MOL CELL CARDIOL 2006;41 (5):914-917 [PubMed]
Linnenbank AC, van Oosterom A, Oostendorp T, van Dessel PFHM, van Rossum AC, Coronel R, Tan HL, de Bakker JMT. Non-invasive imaging of activation times during drug induced conduction changes in: World Congress on Medical Physics and Biomedical Engineering 2006, Seoul. S.l.: s.n.; 2006., p. 2536-2539
Verkerk AO, van Ginneken ACG, Berecki G, den Ruijter HM, Schumacher CA, Veldkamp MW, Baartscheer A, Casini S, Opthof T, Hovenier R, Fiolet JWT, Zock PL, Coronel R, Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials. CARDIOVASC RES 2006;70 (3):509-520 [PubMed]
Wiegerinck RF. Heterogeneously reduced connexin43 expression, conduction velocity and action potential duration during heart failure: implications for arrhythmogenesis. S.l.: s.n.; 2006. 166p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): de Bakker JMT; copromotor(s): Coronel R)
Wiegerinck RF, Verkerk AO, Belterman CN, van Veen TAB, Baartscheer A, Opthof T, Wilders R, de Bakker JMT, Coronel R, Larger cell size in rabbits with heart failure increases myocardial conduction velocity and QRS duration. CIRCULATION 2006;113 (6):806-813 [PubMed]
Baartscheer A, Schumacher CA, van Borren MMGJ, Belterman CNW, Coronel R, Opthof T, Fiolet JWT, Chronic inhibition of Na+/H+-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure. CARDIOVASC RES 2005;65 (1):83-92 [PubMed]
Coronel R, T wave and dispersion of repolarization. HEART RHYTHM 2005;2 (2):170-171 [PubMed]
Coronel R, Casini S, Koopmann TT, Wilms-Schopman FJG, Verkerk AO, de Groot JR, Bhuiyan Z, Bezzina CR, Veldkamp MW, Linnenbank AC, van der Wal AC, Tan HL, Brugada P, Wilde AAM, de Bakker JMT, Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome - A combined electrophysiological, genetic, histopathologic, and computational study. CIRCULATION 2005;112 (18):2769-2777 [PubMed]
Coronel R, Wilms-Schopman FJG, de Groot JR, Opthof T, Taggart P. Stretch-related arrhythmias in: van Hemel NM, Vermeulen FEE, de Bakker JMT, editors. Exclusion or Targetting?. Nieuwegein: Grafische Producties Budde-Elinkwijk; 2005., p. 95-102
Janse MJ, Sosunov EA, Coronel R, Opthof T, Anyukhovsky EP, de Bakker JMT, Plotnikov AN, Shlapakova IN, Danilo P Jr, Tijssen JGP, Rosen MR, Repolarization gradients in the canine left ventricle before and after induction of short-term cardiac memory. CIRCULATION 2005;112 (12):1711-1718 [PubMed]
Opthof T, Coronel R, Transmural dispersion in LQT(3) and arrhythmogenesis. CARDIOVASC RES 2005;68 (2):336-337 [PubMed]
Opthof T, Veldkamp MW, Wilders R, van der Heyden MAG, Taggart P, Coronel R. Role of the autonomic nervous system in: van Hemel NM, Vermeulen FEE, de Bakker JMT, editors. Exclusion or Targetting?. Nieuwegein: Grafische Producties Budde-Elinkwijk; 2005., p. 71-84
Conrath CE, Wilders R, Coronel R, de Bakker JMT, Taggart P, de Groot JR, Opthof T, Intercellular coupling through gap junctions masks M cells in the human heart. CARDIOVASC RES 2004;62 (2):407-414 [PubMed]
de Groot JR, Coronel R, Acute, ischemia-induced gap junctional uncoupling and arrhythmogenesis. CARDIOVASC RES 2004;62 (2):323-334 [PubMed]
Opthof T, Coronel R, Piper HM, Impact factors: no totum pro parte by skewness of citation. CARDIOVASC RES 2004;61 (2):201-203 [PubMed]
Baartscheer A, Schumacher CA, Belterman CNW, Coronel R, Fiolet JWT, [Na+](i) and the driving force of the Na+/Ca2+-exchanger in heart failure. CARDIOVASC RES 2003;57 (4):986-995 [PubMed]
Baartscheer A, Schumacher CA, Belterman CNW, Coronel R, Fiolet JWT, SR calcium handling and calcium after-transients in a rabbit model of heart failure. CARDIOVASC RES 2003;58 (1):99-108 [PubMed]
Baartscheer A, Schumacher CA, van Borren MMGJ, Belterman CNW, Coronel R, Fiolet JWT, Increased Na+/H+-exchange activity is the cause of increased [Na+](i) and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model. CARDIOVASC RES 2003;57 (4):1015-1024 [PubMed]
de Groot JR, Schumacher CA, Verkerk AO, Baartscheer A, Fiolet JWT, Coronel R, Intrinsic heterogeneity in repolarization is increased in isolated failing rabbit cardiomyocytes during simulated ischemia. CARDIOVASC RES 2003;59 (3):705-714 [PubMed]
de Groot JR, Veenstra T, Verkerk AO, Wilders R, Smits JPP, Wilms-Schopman FJG, Wiegerinck RF, Bourier J, Belterman CNW, Coronel R, Verheijck EE, Conduction slowing by the gap junctional uncoupler carbenoxolone. CARDIOVASC RES 2003;60 (2):288-297 [PubMed]
Dekker LRC, van Bavel ET, Opthof T, Coronel R, Janse MJ, Monophasic action potentials and Ca2+ transients in ischaemically preconditioned rabbit ventricular muscle: effects of atp-sensitive K+ channel blockade. NETH HEART J 2003;11 (2):62-69
Janse MJ, Coronel R, Wilms-Schopman FJG, de Groot JR, Mechanical effects on arrhythmogenesis: from pipette to patient. PROG BIOPHYS MOL BIO 2003;82 (1-3):187-195 [PubMed]
Taggart P, Sutton P, Opthof T, Coronel R, Kallis P, Electrotonic cancellation of transmural electrical gradients in the left ventricle in man. PROG BIOPHYS MOL BIO 2003;82 (1-3):243-254 [PubMed]
Verkerk AO, Wilders R, Coronel R, Ravesloot JH, Verheijck EE, Ionic remodeling of sinoatrial node cells by heart failure. CIRCULATION 2003;108 (6):760-766 [PubMed]
Zaitsev AV, Guha PK, Sarmast F, Kolli A, Berenfeld O, Pertsov AM, de Groot JR, Coronel R, Jalife J, Wavebreak formation during ventricular fibrillation in the isolated, regionally ischemic pig heart. CIRC RES 2003;92 (5):546-553 [PubMed]
Coronel R, Repolarization abnormalities in heart failure. CARDIOVASC RES 2002;54 (1):11-12 [PubMed]
Coronel R, Wilms-Schopman FJG, deGroot JR, Origin of ischemia-induced phase 1b ventricular arrhythmias in pig hearts. J AM COLL CARDIOL 2002;39 (1):166-176 [PubMed]
Opthof T, Conrath CE, Wilders R, Taggart P, Coronel R. The transmural gradient of action potential duration in the vivo human heart and in model simulations: is there a contribution of M cells ? in: Schalij MJ, Janse MJ, Oosterom AT, Wellens HJJ, van der Wall EE, editors. Einthoven 2002: 100 years of electrocardiography. Leiden: The Einthoven Foundation; 2002., p. 311-317
Opthof T, Coronel R, Productivity in science: more more and more?. CARDIOVASC RES 2002;56 (2):175-177 [PubMed]
Opthof T, Coronel R, The impact factor of leading cardiovascular journals: Where is your paper best cited ?. NETH HEART J 2002;10 (4):198-202
Opthof T, Coronel R, Janse MJ, Submissions, impact factor, reviewer's recommendations and geographical bias within the peer review system (1997-2002): Focus on Germany. CARDIOVASC RES 2002;55 (2):215-219 [PubMed]
Opthof T, Coronel R, Janse MJ, The significance of the peer review process against the background of bias: priority ratings of reviewers and editors and the prediction of citation, the role of geographical bias. CARDIOVASC RES 2002;56 (3):339-346 [PubMed]
Taggart P, Sutton P, Conrath CE, Coronel R, Wilders R, Opthof T. Electrotonic cancellation of transmural electrical gradients in man in: Kohl P, editors. Proceedings 3rd International Workshop on Cardiac Mechano-Electric Feedback and Arrhythmias; 2002 Sept 6-8; Oxford, England. S.l.: s.n.; 2002., p. 46-47.
van Borren MMGJ, Verkerk AO, Vanharanta SK, Baartscheer A, Coronel R, Ravesloot JH, Reduced swelling-activated Cl- current densities in hypertrophied ventricular myocytes of rabbits with heart failure. CARDIOVASC RES 2002;53 (4):869-878 [PubMed]
Coronel R, Baartscheer A, Rademaker JME, Vermeulen JT, de Bakker JMT. The arrhythmogenic substrate in ischemic and non-ischemic cardiomyopathies in: Liem LB, Downar E, editors. Progress in catheter ablation, clinical application of new mapping and ablation techniques. Boston: Kluwer Academic Publishers; 2001., p. 1-12
Coronel R, de Groot JR, van Lieshout JJ, Defining heart failure. CARDIOVASC RES 2001;50 (3):419-422 [PubMed]
de Groot JR, Wilms-Schopman FJ, Opthof T, Remme CA, Coronel R, Late ventricular arrhythmias during acute regional ischemia in the isolated blood perfused pig heart. Role of electrical cellular coupling. CARDIOVASC RES 2001;50 (2):362-372 [PubMed]
Janse MJ, Vermeulen JT, Opthof T, Coronel R, Wilms-Schopman FJ, Rademaker HM, Baartscheer A, Dekker LR, Arrhythmogenesis in heart failure. J CARDIOVASC ELECTR 2001;12 (4):496-499 [PubMed]
Kawara T, Derksen R, de Groot JR, Coronel R, Tasseron S, Linnenbank AC, Hauer RN, Kirkels H, Janse MJ, de Bakker JM, Activation delay after premature stimulation in chronically diseased human myocardium relates to the architecture of interstitial fibrosis. CIRCULATION 2001;104 (25):3069-3075 [PubMed]
Opthof T, Coronel R, Janse MJ, Impact factor of Cardiovascular Research in 2000: all time high!. CARDIOVASC RES 2001;50 (1):1-2 [PubMed]
Opthof T, Coronel R, Janse MJ, Submissions and impact factor 1997-2001: focus on Sweden. CARDIOVASC RES 2001;51 (2):202-204 [PubMed]
Remme CA, Schumacher CA, de Jong JW, Fiolet JW, de Groot JR, Coronel R, Wilde AA, K(ATP) channel opening during ischemia: effects on myocardial noradrenaline release and ventricular arrhythmias. J CARDIOVASC PHARM 2001;38 (3):406-416 [PubMed]
Taggart P, Sutton PM, Opthof T, Coronel R, Trimlett R, Pugsley W, Kallis P, Transmural repolarisation in the left ventricle in humans during normoxia and ischaemia. CARDIOVASC RES 2001;50 (3):454-462 [PubMed]
Verkerk AO, Veldkamp MW, Coronel R, Wilders R, van Ginneken AC, Effects of cell-to-cell uncoupling and catecholamines on Purkinje and ventricular action potentials: implications for phase-1b arrhythmias. CARDIOVASC RES 2001;51 (1):30-40 [PubMed]
Coronel R, Wilms-Schopman FJ, de Groot JR, Janse MJ, van Capelle FJ, de Bakker JM, Laplacian electrograms and the interpretation of complex ventricular activation patterns during ventricular fibrillation. J CARDIOVASC ELECTR 2000;11 (10):1119-1128 [PubMed]
Opthof T, Coronel R, Electrocardiogram of the normal mouse, Mus musculus: general considerations and genetic aspects. CARDIOVASC RES 2000;45 (1):227-230 [PubMed]
Opthof T, Coronel R, The most frequently cited papers of Cardiovascular Research (1967-1998): 'the Millennium Minutes'. The Editorial Team. CARDIOVASC RES 2000;45 (1):3-5 [PubMed]
Opthof T, Coronel R, Janse MJ, Reviewer's recommendations predict impact: why you have to send us your very best work. CARDIOVASC RES 2000;48 (1):1-3 [PubMed]
Opthof T, Coronel R, Janse MJ, Submissions, editorial process and impact factor 1992-2000: focus on Europe. CARDIOVASC RES 2000;47 (2):203-206 [PubMed]
Opthof T, Coronel R, Janse MJ, Where do our reviewers come from?. CARDIOVASC RES 2000;46 (1):1-13 [PubMed]
Opthof T, Coronel R, Rademaker HM, Vermeulen JT, Wilms-Schopman FJ, Janse MJ, Changes in sinus node function in a rabbit model of heart failure with ventricular arrhythmias and sudden death. CIRCULATION 2000;101 (25):2975-2980 [PubMed]
Opthof T, Furstner F, van Geer M, Coronel R, Regrets or no regrets? No regrets! The fate of rejected manuscripts. CARDIOVASC RES 2000;45 (1):255-258 [PubMed]
Sutton PM, Taggart P, Opthof T, Coronel R, Trimlett R, Pugsley W, Kallis P, Repolarisation and refractoriness during early ischaemia in humans. HEART 2000;84 (4):365-369 [PubMed]
Taggart P, Sutton PM, Opthof T, Coronel R, Trimlett R, Pugsley W, Kallis P, Inhomogeneous transmural conduction during early ischaemia in patients with coronary artery disease. J MOL CELL CARDIOL 2000;32 (4):621-630 [PubMed]
Dekker LR, Coronel R, VanBavel E, Spaan JA, Opthof T, Intracellular Ca2+ and delay of ischemia-induced electrical uncoupling in preconditioned rabbit ventricular myocardium. CARDIOVASC RES 1999;44 (1):101-112 [PubMed]
Dekker LR, Rademaker H, Vermeulen JT, Opthof T, Coronel R, Spaan JA, Janse MJ, Cellular uncoupling during ischemia in hypertrophied and failing rabbit ventricular myocardium: effects of preconditioning. CIRCULATION 1998;97 (17):1724-1730 [PubMed]
Schumacher CA, Baartscheer A, Coronel R, Fiolet JW, Energy-dependent transport of calcium to the extracellular space during acute ischemia of the rat heart. J MOL CELL CARDIOL 1998;30 (8):1631-1642 [PubMed]
Simmers TA, de Bakker JM, Coronel R, Wittkampf FH, van Capelle FJ, Janse MJ, Hauer RN, Effects of intracavitary blood flow and electrode-target distance on radiofrequency power required for transient conduction block in a Langendorff-perfused canine model. J AM COLL CARDIOL 1998;31 (1):231-235 [PubMed]
Coronel R, Opthof T, Taggart P, Tytgat J, Veldkamp M, Differential electrophysiology of repolarisation from clone to clinic. CARDIOVASC RES 1997;33 (3):503-517 [PubMed]
Coronel R, Wilms-Schopman FJ, Janse MJ, Profibrillatory effects of intracoronary thrombus in acute regional ischemia of the in situ porcine heart. CIRCULATION 1997;96 (11):3985-3991 [PubMed]
Levi M, Coronel R, Gene therapy in the cardiovascular system. CARDIOVASC RES 1997;35 (3):389-390 [PubMed]
Dekker LR, Fiolet JW, VanBavel E, Coronel R, Opthof T, Spaan JA, Janse MJ, Intracellular Ca2+, intercellular electrical coupling, and mechanical activity in ischemic rabbit papillary muscle. Effects of preconditioning and metabolic blockade. CIRC RES 1996;79 (2):237-246 [PubMed]
Vermeulen JT, Tan HL, Rademaker H, Schumacher CA, Loh P, Opthof T, Coronel R, Janse MJ, Electrophysiologic and extracellular ionic changes during acute ischemia in failing and normal rabbit myocardium. J MOL CELL CARDIOL 1996;28 (1):123-131 [PubMed]
Biemond BJ, Levi M, Coronel R, Janse MJ, ten Cate JW, Pannekoek H, Thrombolysis and reocclusion in experimental jugular vein and coronary artery thrombosis. Effects of a plasminogen activator inhibitor type 1-neutralizing monoclonal antibody. CIRCULATION 1995;91 (4):1175-1181 [PubMed]
Coronel R, Wilms-Schopman FJ, Dekker LR, Janse MJ, Heterogeneities in [K+]o and TQ potential and the inducibility of ventricular fibrillation during acute regional ischemia in the isolated perfused porcine heart. CIRCULATION 1995;92 (1):120-129 [PubMed]
Coronel R, Wilms-Schopman FJ, Fiolet JW, Opthof T, Janse MJ, The relation between extracellular potassium concentration and pH in the border zone during regional ischemia in isolated porcine hearts. J MOL CELL CARDIOL 1995;27 (9):2069-2073 [PubMed]
Janse MJ, Wilms-Schopman FJ, Coronel R, Ventricular fibrillation is not always due to multiple wavelet reentry. J CARDIOVASC ELECTR 1995;6 (7):512-521 [PubMed]
Coronel R, Heterogeneity in extracellular potassium concentration during early myocardial ischaemia and reperfusion: implications for arrhythmogenesis. CARDIOVASC RES 1994;28 (6):770-777 [PubMed]
Coronel R, Never say never again. CARDIOVASC RES 1994;28 (11):1735 [PubMed]
de Bakker JM, Coronel R, McGuire MA, Vermeulen JT, Opthof T, Tasseron S, van Hemel NM, Defauw JJ, Slow potentials in the atrioventricular junctional area of patients operated on for atrioventricular node tachycardias and in isolated porcine hearts. J AM COLL CARDIOL 1994;23 (3):709-715 [PubMed]
Vermeulen JT, McGuire MA, Opthof T, Coronel R, de Bakker JM, Klöpping C, Janse MJ, Triggered activity and automaticity in ventricular trabeculae of failing human and rabbit hearts. CARDIOVASC RES 1994;28 (10):1547-1554 [PubMed]
Fiolet JW, Schumacher CA, Baartscheer A, Coronel R, Osmotic changes and transsarcolemmal ion transport during total ischaemia of isolated rat ventricular myocytes. BASIC RES CARDIOL 1993;88 (5):396-410 [PubMed]
Opthof T, Coronel R, Vermeulen JT, Verberne HJ, van Capelle FJ, Janse MJ, Dispersion of refractoriness in normal and ischaemic canine ventricle: effects of sympathetic stimulation. CARDIOVASC RES 1993;27 (11):1954-1960 [PubMed]
Opthof T, Dekker LR, Coronel R, Vermeulen JT, van Capelle FJ, Janse MJ, Interaction of sympathetic and parasympathetic nervous system on ventricular refractoriness assessed by local fibrillation intervals in the canine heart. CARDIOVASC RES 1993;27 (5):753-759 [PubMed]
Tan HL, Mazón P, Verberne HJ, Sleeswijk ME, Coronel R, Opthof T, Janse MJ, Ischaemic preconditioning delays ischaemia induced cellular electrical uncoupling in rabbit myocardium by activation of ATP sensitive potassium channels. CARDIOVASC RES 1993;27 (4):644-651 [PubMed]
Tan HL, Netea AO, Sleeswijk ME, Mazón P, Coronel R, Opthof T, Janse MJ, R 56865 delays cellular electrical uncoupling in ischemic rabbit papillary muscle. J MOL CELL CARDIOL 1993;25 (9):1059-1066 [PubMed]
Cinca J, Worner F, Carreño A, Coronel R, Soldevilla A, Pérez-Villa F, Janse MJ, Soler-Soler J, T-Q, S-T segment mapping and hyperemia in reperfused pig heart with ischemic preconditioning. AM J PHYSIOL 1992;263 (6 Part 2):H1732-H1738 [PubMed]
Coronel R, Fiolet JW, Janse MJ, Vermeulen JT, The premature beat. CARDIOVASC RES 1992;26 (7):720 [PubMed]
Coronel R, Wilms-Schopman FJ, Opthof T, Cinca J, Fiolet JW, Janse MJ, Reperfusion arrhythmias in isolated perfused pig hearts. Inhomogeneities in extracellular potassium, ST and TQ potentials, and transmembrane action potentials. CIRC RES 1992;71 (5):1131-1142 [PubMed]
Coronel R, Wilms-Schopman FJ, Opthof T, van Capelle FJ, Janse MJ, Injury current and gradients of diastolic stimulation threshold, TQ potential, and extracellular potassium concentration during acute regional ischemia in the isolated perfused pig heart. CIRC RES 1991;68 (5):1241-1249 [PubMed]
Heijnis JB, Coronel R, van Zwieten PA, The effects of calcium antagonists on extracellular potassium accumulation during global ischaemia in isolated perfused rat hearts. CARDIOVASC DRUG THER 1991;5 (6):1035-1041 [PubMed]
Opthof T, Misier AR, Coronel R, Vermeulen JT, Verberne HJ, Frank RG, Moulijn AC, van Capelle FJ, Janse MJ, Dispersion of refractoriness in canine ventricular myocardium. Effects of sympathetic stimulation. CIRC RES 1991;68 (5):1204-1215 [PubMed]
de Bakker JM, Coronel R, Tasseron S, Wilde AA, Opthof T, Janse MJ, van Capelle FJ, Becker AE, Jambroes G, Ventricular tachycardia in the infarcted, Langendorff-perfused human heart: role of the arrangement of surviving cardiac fibers. J AM COLL CARDIOL 1990;15 (7):1594-1607 [PubMed]
Schaapherder AF, Schumacher CA, Coronel R, Fiolet JW, Transmural inhomogeneity of extracellular [K+] and pH and myocardial energy metabolism in the isolated rat heart during acute global ischemia; dependence on gaseous environment. BASIC RES CARDIOL 1990;85 (1):33-44 [PubMed]
Coronel R, Fiolet JW, Wilms-Schopman JG, Opthof T, Schaapherder AF, Janse MJ, Distribution of extracellular potassium and electrophysiologic changes during two-stage coronary ligation in the isolated, perfused canine heart. CIRCULATION 1989;80 (1):165-177 [PubMed]
Coronel R, Fiolet JW, Wilms-Schopman FJ, Schaapherder AF, Johnson TA, Gettes LS, Janse MJ, Distribution of extracellular potassium and its relation to electrophysiologic changes during acute myocardial ischemia in the isolated perfused porcine heart. CIRCULATION 1988;77 (5):1125-1138 [PubMed]
de Bakker JM, van Capelle FJ, Janse MJ, Wilde AA, Coronel R, Becker AE, Dingemans KP, van Hemel NM, Hauer RN, Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlation. CIRCULATION 1988;77 (3):589-606 [PubMed]
Johnson TA, Coronel R, Graebner CA, Buchanan JW, Janse MJ, Gettes LS, Relationship between extracellular potassium accumulation and local TQ-segment potential during acute myocardial ischemia in the porcine. J MOL CELL CARDIOL 1987;19 (10):949-952 [PubMed]
Janse MJ, Kleber AG, Capucci A, Coronel R, Wilms-Schopman F, Electrophysiological basis for arrhythmias caused by acute ischemia. Role of the subendocardium. J MOL CELL CARDIOL 1986;18 (4):339-355 [PubMed]
Kléber AG, Janse MJ, Wilms-Schopmann FJ, Wilde AA, Coronel R, Changes in conduction velocity during acute ischemia in ventricular myocardium of the isolated porcine heart. CIRCULATION 1986;73 (1):189-198 [PubMed]
Wilensky RL, Tranum-Jensen J, Coronel R, Wilde AA, Fiolet JW, Janse MJ, The subendocardial border zone during acute ischemia of the rabbit heart: an electrophysiologic, metabolic, and morphologic correlative study. CIRCULATION 1986;74 (5):1137-1146 [PubMed]
Janse MJ, Capucci A, Coronel R, Fabius MA, Variability of recovery of excitability in the normal canine and the ischaemic porcine heart. EUR HEART J 1985;6 (Suppl. D):41-52 [PubMed]
Fiolet JW, Baartscheer A, Schumacher CA, Coronel R, ter Welle HF, The change of the free energy of ATP hydrolysis during global ischemia and anoxia in the rat heart. Its possible role in the regulation of transsarcolemmal sodium and potassium gradients. J MOL CELL CARDIOL 1984;16 (11):1023-1036 [PubMed]
Key publications

Boukens BJ, Sylva M, de Gier-de Vries C, Remme CA, Bezzina CR, Christoffels VM, Coronel R, Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract. CIRC RES 2013;113 (2):137-141 [PubMed]
ten Sande JN , Smit NW, Parvizi M, van Amersfoorth SCM, Plantinga JA, van Dessel PFHM, de Bakker JMT, Harmsen MC, Coronel R, Differential Mechanisms of Myocardial Conduction Slowing by Adipose Tissue-Derived Stromal Cells Derived From Different Species. STEM CELL TRANSL MED 2017;6 (1):22-30 [PubMed]
Baartscheer A, Schumacher CA, Wekker V, Verkerk AO, Veldkamp MW, van Oort RJ, Elzenaar I, Ottenhoff R, van Roomen C, Aerts H, Coronel R, Dyscholesterolemia Protects Against Ischemia-Induced Ventricular Arrhythmias. CIRC-ARRHYTHMIA ELEC 2015;8 (6):1481-1490 [PubMed]
den Ruijter HM, Verkerk AO, Schumacher CA, Houten SM, Belterman CNW, Baartscheer A, Brouwer IA, van Bilsen M, de Roos B, Coronel R, A Diet Rich in Unsaturated Fatty Acids Prevents Progression Toward Heart Failure in a Rabbit Model of Pressure and Volume Overload. CIRC-HEART FAIL 2012;5 (3):376-384 [PubMed]
den Ruijter HM, Franssen R, Verkerk AO, van Wijk DF, Vaessen SF, Holleboom AG, Levels JH, Opthof T, Sungnoon R, Stroes ES, Kuivenhoven JA, Coronel R, Reconstituted High-Density Lipoprotein Shortens Cardiac Repolarization. J AM COLL CARDIOL 2011;58 (1):40-44 [PubMed]


All Publications

Research programmes

Mechanisms of sudden cardiac death

Faculty
Dr. R. Coronel MD PhD
Dr. A. Baartscheer
Dr. M.W. Veldkamp

Postdocs
Dr. drs. V.M.F. Meijborg (NHI)

PhD Students
Drs. N.W. Smit
L.A. Gottlieb MD (Bordeaux University)

Others
C.N.W. Belterman BA
C.A. Schumacher BA

Other research related activities
  • None reported
Current research funding
  • Bayer AG