Motor dysfunctions and neuromuscular diseases
AMC is a participant in the ALS Centre, which brings together scientific knowledge about amyotrophic lateral sclerosis. A lot of work is also done on neuropathies and muscular dystrophy, and on the effects of the surgical treatment of Parkinson’s disease.
Cerebrovascular diseases and dementia
At the heart of this topic is brain ischaemia. Work includes investigations of the pathogenesis and treatment of cerebral infarctions, subarachnoid haemorrhages, cerebral venous sinus thrombosis and brain damage following acute circulatory failure. Another important line of research is bacterial meningitis.
AMC psychiatric research focuses mainly on the development of treatments for a number of specific conditions: anxiety and compulsive disorders, schizophrenia in its early phase, mood disorders, posttraumatic stress disorder and addiction. Research is also being conducted into the pathogenesis of these conditions, some of it with the aid of imaging techniques. Several major international studies are looking at the vulnerability of growing brains to such psychopharmaceuticals as methylphenidate – which is being used to treat an estimated 32,000 young people with ADHD (hyperactivity) in the Netherlands alone – and the antidepressant fluoxetine.