• Principal Investigator
  • Male

Dr. A.J. Bredenoord

Position:
Main activities: Patient care, Research
Specialisation:
foto A.J. Bredenoord is one of the AMC Principal Investigators
Focus of research:

Oesophageal motility, Gastro-oesophageal reflux disease

AMC themes: Metabolic disorders and gastrointestinal diseases
Departments: Gastroenterology and Hepatology
Gyawali CP, Roman S, Bredenoord AJ, Fox M, Keller J, Pandolfino JE, Sifrim D, Tatum R, Yadlapati R, Savarino E [Contributors: Azpiroz F, Babaei A, Bhatia S, Boeckxstaens G, Bor S, Carlson D, Castell D, Cicala M, Clarke J, de Bortoli N, Drug V, Frazzoni M, Holloway R, Kahrilas P, Kandulski A, Katz P, Katzka D, Mittal R, Mion F, Novais L, Patel A, Penagini R, Ribolsi M, Richter J, Salvador R, Savarino V, Serra J, Schnoll-Sussman F, Smout A, Soffer E, Sweis R, Tack J, Tolone S, Tutuian R, Vaezi M, Vela M, Woodland P, Wu J, Xiao Y, Zerbib F]] , Classification of esophageal motor findings in gastro-esophageal reflux disease: Conclusions from an international consensus group. NEUROGASTROENT MOTIL 2017;ahead of print [PubMed]
Herregods TVK. Towards better understanding of symptoms associated with disordered esophageal function. S.l.: s.n.; 2017. 195p. ISBN 978-94-6182-816-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Smout AJPM; copromotor(s): Bredenoord AJ)
Herregods TVK, Bredenoord AJ, Oors JM, Bogte A, Smout AJPM, Determinants of the Association between Non-Cardiac Chest Pain and Reflux. AM J GASTROENTEROL 2017;112 (11):1671-1677 [PubMed]
Herregods TVK, Pauwels A, Jafari J, Sifrim D, Bredenoord AJ, Tack J, Smout AJPM, Determinants of reflux-induced chronic cough. GUT 2017;ahead of print [PubMed]
Herregods TVK, Pauwels A, Jafari J, Sifrim D, Smout AJPM, Bredenoord AJ, Tack J, Ambulatory pH-impedance-pressure monitoring as a diagnostic tool for the reflux-cough syndrome. DIS ESOPHAGUS 2017;ahead of print [PubMed]
Herregods TVK, Pauwels A, Tack J, Smout AJPM, Bredenoord AJ, Reflux-cough syndrome: Assessment of temporal association between reflux episodes and cough bursts. NEUROGASTROENT MOTIL 2017;ahead of print [PubMed]
Herregods TVK, Smout AJPM, Ooi JLS, Sifrim D, Bredenoord AJ, Jackhammer esophagus: Observations on a European cohort. NEUROGASTROENT MOTIL 2017;29 (4):UNSP e12975 [PubMed]
Herregods TVK, van Hoeij FB, Bredenoord AJ, Smout AJPM, Subtle lower esophageal sphincter relaxation abnormalities in patients with unexplained esophageal dysphagia. NEUROGASTROENT MOTIL 2017;ahead of print [PubMed]
Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJPM, Pandolfino JE, Advances in the management of oesophageal motility disorders in the era of high-resolution manometry: a focus on achalasia syndromes. NAT REV GASTRO HEPAT 2017;14 (11):677-+ [PubMed]
Lucendo AJ, Molina-Infante J, Arias Á, von Arnim U, Bredenoord AJ, Bussmann C, Amil Dias J, Bove M, González-Cervera J, Larsson H, Miehlke S, Papadopoulou A, Rodríguez-Sánchez J, Ravelli A, Ronkainen J, Santander C, Schoepfer AM, Storr MA, Terreehorst I, Straumann A, Attwood SE, Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults. UNITED EUR GASTROENT 2017;5 (3):335-358 [PubMed]
Ponds FA, Bredenoord AJ, Kessing BF, Smout AJPM, Esophagogastric junction distensibility identifies achalasia subgroup with manometrically normal esophagogastric junction relaxation. NEUROGASTROENT MOTIL 2017;29 (1):UNSP e12908 [PubMed]
Ponds FA, van Raath MI, Mohamed SMM, Smout AJPM, Bredenoord AJ, Diagnostic features of malignancy-associated pseudoachalasia. ALIMENT PHARM THER 2017;45 (11):1449-1458 [PubMed]
Rohof WOA, Bredenoord AJ, Chicago Classification of Esophageal Motility Disorders: Lessons Learned. CURR GASTROENTEROL REP 2017;19 (8):37 [PubMed]
Roman S, Gyawali CP, Savarino E, Yadlapati R, Zerbib F, Wu J, Vela M, Tutuian R, Tatum R, Sifrim D, Keller J, Fox M, Pandolfino JE, Bredenoord AJ [Contributors: Azpiroz F, Babaei A, Bhatia S, Boeckxstaens G, Bor S, Carlson D, Castell D, Cicala M, Clarke J, de Bortoli N, Drug V, Frazzoni M, Holloway R, Kahrilas P, Kandulski A, Katz P, Katzka D, Mittal R, Mion F, Novais L, Patel A, Penagini R, Ribolsi M, Richter J, Salvador R, Savarino V, Serra J, Schnoll-Sussman F, Smout A, Soffer E, Sweis R, Tack J, Tolone S, Vaezi M, Woodland P, Xiao Y]] , Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: Update of the Porto consensus and recommendations from an international consensus group. NEUROGASTROENT MOTIL 2017;29 (10):e13067 [PubMed]
Roman S, Holloway R, Keller J, Herbella F, Zerbib F, Xiao Y, Bernard L, Bredenoord AJ, Bruley des Varannes S, Chen M, Fox M, Kahrilas PJ, Mittal RK, Penagini R, Savarino E, Sifrim D, Wu J, Decullier E, Pandolfino JE, Mion F, Validation of criteria for the definition of transient lower esophageal sphincter relaxations using high-resolution manometry. NEUROGASTROENT MOTIL 2017;29 (2):UNSP e12920 [PubMed]
Savarino E, Bredenoord AJ, Fox M, Pandolfino JE, Roman S, Gyawali CP, Advances in the physiological assessment and diagnosis of GERD. NAT REV GASTRO HEPAT 2017;14 (11):665-676 [PubMed]
Singendonk MMJ, Oors JM, Bredenoord AJ, Omari TI, van der Pol RJ, Smits MJ, Benninga MA, van Wijk MP, Objectively diagnosing rumination syndrome in children using esophageal pH-impedance and manometry. NEUROGASTROENT MOTIL 2017;29 (5):UNSP e12996 [PubMed]
van Hoeij FB, Bredenoord AJ, Retreatment after failure of per-oral endoscopic myotomy: Does "cutting" fare better than "stretching"? Response. GASTROINTEST ENDOSC 2017;86 (5):928 [PubMed]
van Hoeij FB, Ponds FA, Smout AJ, Bredenoord AJ, Incidence and costs of achalasia in The Netherlands. NEUROGASTROENT MOTIL 2017;ahead of print [PubMed]
van Hoeij FB, Ponds FA, Werner Y, Sternbach JM, Fockens P, Bastiaansen BA, Smout AJ, Pandolfino JE, Rösch T, Bredenoord AJ, Management of recurrent symptoms after per-oral endoscopic myotomy in achalasia. GASTROINTEST ENDOSC 2017;-:- [PubMed]
van Hoeij FB, Smout AJPM, Bredenoord AJ, Esophageal stasis in achalasia patients without symptoms after treatment does not predict symptom recurrence. NEUROGASTROENT MOTIL 2017;29 (8):e13059 [PubMed]
van Hoeij FB, Tack JF, Pandolfino JE, Sternbach JM, Roman S, Smout AJPM, Bredenoord AJ, Complications of botulinum toxin injections for treatment of esophageal motility disorders†. DIS ESOPHAGUS 2017;30 (3):1-5 [PubMed]
van Rhijn BD, Bredenoord AJ, Management of Eosinophilic Esophagitis Based on Pathophysiological Evidence. J CLIN GASTROENTEROL 2017;51 (8):659-668 [PubMed]
Warners MJ, de Rooij W, van Rhijn BD, Verheij J, Bruggink AH, Smout AJPM, Bredenoord AJ, Incidence of eosinophilic esophagitis in the Netherlands continues to rise: 20-year results from a nationwide pathology database. NEUROGASTROENT MOTIL 2017;ahead of print [PubMed]
Warners MJ, Hindryckx P, Levesque BG, Parker CE, Shackelton LM, Khanna R, Sandborn WJ, D'Haens GR, Feagan BG, Bredenoord AJ, Jairath V, Systematic Review: Disease Activity Indices in Eosinophilic Esophagitis. AM J GASTROENTEROL 2017;112 (11):1658-1669 [PubMed]
Warners MJ, Terreehorst I, van den Wijngaard RM, Akkerdaas J, van Esch BCAM, van Ree R, Versteeg SA, Smout AJPM, Bredenoord AJ, Abnormal Responses to Local Esophageal Food Allergen Injections in Adult Patients with Eosinophilic Esophagitis. GASTROENTEROLOGY 2017;ahead of print [PubMed]
Warners MJ, van Rhijn BD, Verheij J, Smout AJPM, Bredenoord AJ, Disease activity in eosinophilic esophagitis is associated with impaired esophageal barrier integrity. AM J PHYSIOL-GASTR L 2017;313 (3):G230-G238 [PubMed]
Warners MJ, Vlieg-Boerstra BJ, Verheij J, van Hamersveld PHP, van Rhijn BD, van Ampting MTJ, Harthoorn LF, de Jonge WJ, Smout AJPM, Bredenoord AJ, Esophageal and Small Intestinal Mucosal Integrity in Eosinophilic Esophagitis and Response to an Elemental Diet. AM J GASTROENTEROL 2017;112 (7):1061-1071 [PubMed]
Warners MJ, Vlieg-Boerstra BJ, Verheij J, van Rhijn BD, van Ampting MTJ, Harthoorn LF, de Jonge WJ, Smout AJPM, Bredenoord AJ, Elemental diet decreases inflammation and improves symptoms in adult eosinophilic oesophagitis patients. ALIMENT PHARM THER 2017;45 (6):777-787 [PubMed]
Weijenborg PW, Smout AJPM, Krishnadath KK, Bergman JGHM, Verheij J, Bredenoord AJ, Esophageal sensitivity to acid in patients with Barrett's esophagus is not related to preserved esophageal mucosal integrity. NEUROGASTROENT MOTIL 2017;29 (7):e13066 [PubMed]
Barret M, Herregods TVK, Oors JM, Smout AJPM, Bredenoord AJ, Diagnostic yield of 24-hour esophageal manometry in non-cardiac chest pain. NEUROGASTROENT MOTIL 2016;28 (8):1186-1193 [PubMed]
Bredenoord AJ, Peroral endoscopic myotomy: ready for prime time in all achalasia patients?. ENDOSCOPY 2016;48 (12):1055-1056 [PubMed]
Bredenoord AJ, Browning KN, Mawe GM, Galligan JJ, Simren M, News from the editors of Neurogastroenterology and Motility. NEUROGASTROENT MOTIL 2016;28 (10):1451 [PubMed]
de Schepper HU, Ponds FAM, Oors JM, Smout AJPM, Bredenoord AJ, Distal esophageal spasm and the Chicago classification: is timing everything?. NEUROGASTROENT MOTIL 2016;28 (2):260-265 [PubMed]
Herregods TVK, van Hoeij FB, Oors JM, Bredenoord AJ, Smout AJPM, Effect of Running on Gastroesophageal Reflux and Reflux Mechanisms. AM J GASTROENTEROL 2016;111 (7):940-946 [PubMed]
Kessing BF, Bredenoord AJ, Smout AJPM, A pregnant patient with excessive belching. DIS ESOPHAGUS 2016;29 (6):688-689 [PubMed]
Molina-Infante J, Bredenoord AJ, Cheng E, Dellon ES, Furuta GT, Gupta SK, Hirano I, Katzka DA, Moawad FJ, Rothenberg ME, Schoepfer A, Spechler SJ, Wen T, Straumann A, Lucendo AJ, Proton pump inhibitor-responsive oesophageal eosinophilia: an entity challenging current diagnostic criteria for eosinophilic oesophagitis. GUT 2016;65 (3):524-U196 [PubMed]
Moonen A, Annese V, Belmans A, Bredenoord AJ, Bruley des Varannes S, Costantini M, Dousset B, Elizalde JI, Fumagalli U, Gaudric M, Merla A, Smout AJ, Tack J, Zaninotto G, Busch OR, Boeckxstaens GE, Long-term results of the European achalasia trial: a multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy. GUT 2016;65 (5):732-739 [PubMed]
Saleh CMG, Ponds FAM, Schijven MP, Smout AJPM, Bredenoord AJ, Efficacy of pneumodilation in achalasia after failed Heller myotomy. NEUROGASTROENT MOTIL 2016;28 (11):1741-1746 [PubMed]
Smout AJPM, Bredenoord AJ, GERD: A challenge to our view of reflux oesophagitis pathogenesis. NAT REV GASTRO HEPAT 2016;13 (9):504-505 [PubMed]
van Hoeij FB, Bredenoord AJ, Clinical Application of Esophageal High-resolution Manometry in the Diagnosis of Esophageal Motility Disorders. J NEUROGASTROENTEROL 2016;22 (1):6-13 [PubMed]
van Hoeij FB, Weijenborg PW, van den Bergh Weerman MA, van den Wijngaard RMJGJ, Verheij J, Smout AJPM, Bredenoord AJ, Mucosal integrity and sensitivity to acid in the proximal esophagus in patients with gastroesophageal reflux disease. AM J PHYSIOL-GASTR L 2016;311 (1):G117-G122 [PubMed]
van Rhijn BD, Bredenoord AJ, Response to Farré. AM J GASTROENTEROL 2016;111 (2):296-297 [PubMed]
van Rhijn BD, Verheij J, Smout AJPM, Bredenoord AJ, The Endoscopic Reference Score shows modest accuracy to predict histologic remission in adult patients with eosinophilic esophagitis. NEUROGASTROENT MOTIL 2016;28 (11):1714-1722 [PubMed]
Verlaan T, Ponds FAM, Bastiaansen BAJ, Bredenoord AJ, Fockens P, Single clips versus multi-firing clip device for closure of mucosal incisions after peroral endoscopic myotomy (POEM). ENDOSC INT OPEN 2016;4 (10):E1052-E1056 [PubMed]
Weijenborg PW. Reflux perception and the esophageal mucosal barrier in gastroesophageal reflux disease. S.l.: s.n.; 2016. 223p. ISBN 978-94-6182-636-7 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Smout AJPM; copromotor(s): Bredenoord AJ)
Weijenborg PW, Smout AJPM, Bredenoord AJ, Esophageal acid sensitivity and mucosal integrity in patients with functional heartburn. NEUROGASTROENT MOTIL 2016;28 (11):1649-1654 [PubMed]
Bogte A, Bredenoord AJ, Oors J, Siersema PD, Smout AJPM, Assessment of bolus transit with intraluminal impedance measurement in patients with esophageal motility disorders. NEUROGASTROENT MOTIL 2015;27 (10):1446-1452 [PubMed]
Bolier EA, Kessing BF, Smout AJ, Bredenoord AJ, Systematic review: questionnaires for assessment of gastroesophageal reflux disease. DIS ESOPHAGUS 2015;28 (2):105-120 [PubMed]
Bredenoord AJ, Clinical esophagology: alive and kicking!. NEUROGASTROENT MOTIL 2015;27 (2):157-159 [PubMed]
Bredenoord AJ, Minor Disorders of Esophageal Peristalsis: Highly Prevalent, Minimally Relevant?. CLIN GASTROENTEROL H 2015;13 (8):1424-1425 [PubMed]
Bredenoord AJ, Hirano I, Eosinophilic esophagitis : Preface. BEST PRACT RES CL GA 2015;29 (5):699 [PubMed]
Carlson DA, Ravi K, Kahrilas PJ, Gyawali CP, Bredenoord AJ, Castell DO, Spechler SJ, Halland M, Kanuri N, Katzka DA, Leggett CL, Roman S, Saenz JB, Sayuk GS, Wong AC, Yadlapati R, Ciolino JD, Fox MR, Pandolfino JE, Diagnosis of Esophageal Motility Disorders: Esophageal Pressure Topography vs. Conventional Line Tracing. AM J GASTROENTEROL 2015;110 (7):967-77; quiz 978 [PubMed]
Fox MR, Pandolfino JE, Sweis R, Sauter M, Abreu Y Abreu AT, Anggiansah A, Bogte A, Bredenoord AJ, Dengler W, Elvevi A, Fruehauf H, Gellersen S, Ghosh S, Gyawali CP, Heinrich H, Hemmink M, Jafari J, Kaufman E, Kessing K, Kwiatek M, Lubomyr B, Banasiuk M, Mion F, Pérez-de-la-Serna J, Remes-Troche JM, Rohof W, Roman S, Ruiz-de-León A, Tutuian R, Uscinowicz M, Valdovinos MA, Vardar R, Velosa M, Waśko-Czopnik D, Weijenborg P, Wilshire C, Wright J, Zerbib F, Menne D, Inter-observer agreement for diagnostic classification of esophageal motility disorders defined in high-resolution manometry. DIS ESOPHAGUS 2015;28 (8):711-719 [PubMed]
Herregods TVK, Bredenoord AJ, Smout AJPM, Pathophysiology of gastroesophageal reflux disease: new understanding in a new era. NEUROGASTROENT MOTIL 2015;27 (9):1202-1213 [PubMed]
Herregods TVK, Roman S, Kahrilas PJ, Smout AJPM, Bredenoord AJ, Normative values in esophageal high-resolution manometry. NEUROGASTROENT MOTIL 2015;27 (2):175-187 [PubMed]
Herregods TVK, Troelstra M, Weijenborg PW, Bredenoord AJ, Smout AJPM, Patients with refractory reflux symptoms often do not have GERD. NEUROGASTROENT MOTIL 2015;27 (9):1267-1273 [PubMed]
Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJPM, Pandolfino JE, The Chicago Classification of esophageal motility disorders, v3.0. NEUROGASTROENT MOTIL 2015;27 (2):160-174 [PubMed]
Kappelle WFW, Bredenoord AJ, Conchillo JM, Ruurda JP, Bouvy ND, van Berge Henegouwen MI, Chiu PW, Booth M, Hani A, Reddy DN, Bogte A, Smout AJPM, Wu JC, Escalona A, Valdovinos MA, Torres-Villalobos G, Siersema PD, Electrical stimulation therapy of the lower oesophageal sphincter for refractory gastro-oesophageal reflux disease - interim results of an international multicentre trial. ALIMENT PHARM THER 2015;42 (5):614-625 [PubMed]
Kessing BF. Reflux, belching, rumination and their interrelationships. S.l.: s.n.; 2015. 193p. ISBN 978-94-6182-550-6 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Smout AJPM; copromotor(s): Bredenoord AJ)
Kessing BF, Bredenoord AJ, Saleh CMG, Smout AJPM, Effects of anxiety and depression in patients with gastroesophageal reflux disease. CLIN GASTROENTEROL H 2015;13 (6):1089-95.e1 [PubMed]
Kessing BF, Bredenoord AJ, Schijven MP, van der Peet DL, van Berge Henegouwen MI, Smout AJPM, Long-term effects of anti-reflux surgery on the physiology of the esophagogastric junction. SURG ENDOSC 2015;29 (12):3726-3732 [PubMed]
Molina-Infante J, Rodriguez-Sanchez J, Martinek J, van Rhijn BD, Krajciova J, Rivas MD, Barrio J, Moawad FJ, Martinez-Alcalá C, Bredenoord AJ, Zamorano J, Dellon ES, Long-Term Loss of Response in Proton Pump Inhibitor-Responsive Esophageal Eosinophilia Is Uncommon and Influenced by CYP2C19 Genotype and Rhinoconjunctivitis. AM J GASTROENTEROL 2015;110 (11):1567-1575 [PubMed]
Ponds FAM, Smout AJPM, Bredenoord AJ, Fockens P, Perorale endoscopische myotomie bij achalasie. NED TIJDSCHR GENEESKD 2015;159:A8813 [PubMed]
Saleh CMG, Smout AJPM, Bredenoord AJ, The diagnosis of gastro-esophageal reflux disease cannot be made with barium esophagograms. NEUROGASTROENT MOTIL 2015;27 (2):195-200 [PubMed]
Smits MJ, Loots CM, van Wijk MP, Bredenoord AJ, Benninga MA, Smout AJPM, An expert panel-based study on recognition of gastro-esophageal reflux in difficult esophageal pH-impedance tracings. NEUROGASTROENT MOTIL 2015;27 (5):637-645 [PubMed]
Tack J, Zerbib F, Blondeau K, des Varannes SB, Piessevaux H, Borovicka J, Mion F, Fox M, Bredenoord AJ, Louis H, Dedrie S, Hoppenbrouwers M, Meulemans A, Rykx A, Thielemans L, Ruth M, Randomized clinical trial: effect of the 5-HT4 receptor agonist revexepride on reflux parameters in patients with persistent reflux symptoms despite PPI treatment. NEUROGASTROENT MOTIL 2015;27 (2):258-268 [PubMed]
van Hoeij FB, Smout AJ, Bredenoord AJ, Predictive value of routine esophageal high-resolution manometry for gastro-esophageal reflux disease. NEUROGASTROENT MOTIL 2015;27 (7):963-970 [PubMed]
van Hoeij FB, Smout AJPM, Bredenoord AJ, Characterization of idiopathic esophagogastric junction outflow obstruction. NEUROGASTROENT MOTIL 2015;27 (9):1310-1316 [PubMed]
van Rhijn BD, Verheij J, van den Bergh Weerman MA, Verseijden C, van den Wijngaard RMJGJ, de Jonge WJ, Smout AJPM, Bredenoord AJ, Histological Response to Fluticasone Propionate in Patients With Eosinophilic Esophagitis Is Associated With Improved Functional Esophageal Mucosal Integrity. AM J GASTROENTEROL 2015;110 (9):1289-1297 [PubMed]
van Rhijn BD, Vlieg-Boerstra BJ, Versteeg SA, Akkerdaas JH, van Ree R, Terreehorst I, Sprikkelman AB, Verheij J, Smout AJPM, Bredenoord AJ, Evaluation of allergen-microarray-guided dietary intervention as treatment of eosinophilic esophagitis. J ALLERGY CLIN IMMUN 2015;136 (4):1095-7.e3 [PubMed]
Warners MJ, van Rhijn BD, Curvers WL, Smout AJPM, Bredenoord AJ, PPI-responsive esophageal eosinophilia cannot be distinguished from eosinophilic esophagitis by endoscopic signs. EUR J GASTROEN HEPAT 2015;27 (5):506-511 [PubMed]
Warners MJ, Vlieg-Boerstra BJ, Bredenoord AJ, Elimination and elemental diet therapy in eosinophilic oesophagitis. BEST PRACT RES CL GA 2015;29 (5):793-803 [PubMed]
Weijenborg PW, de Schepper HS, Smout AJPM, Bredenoord AJ, Effects of antidepressants in patients with functional esophageal disorders or gastroesophageal reflux disease: a systematic review. CLIN GASTROENTEROL H 2015;13 (2):251-259.e1 [PubMed]
Weijenborg PW, Savarino E, Kessing BF, Roman S, Costantini M, Oors JM, Smout AJPM, Bredenoord AJ, Normal values of esophageal motility after antireflux surgery; a study using high-resolution manometry. NEUROGASTROENT MOTIL 2015;27 (7):929-935 [PubMed]
Weijenborg PW, van Hoeij FB, Smout AJPM, Bredenoord AJ, Accuracy of hiatal hernia detection with esophageal high-resolution manometry. NEUROGASTROENT MOTIL 2015;27 (2):293-299 [PubMed]
Bogte A, Bredenoord AJ, Oors J, Siersema PD, Smout AJPM, Sensation of stasis is poorly correlated with impaired esophageal bolus transport. NEUROGASTROENT MOTIL 2014;26 (4):538-545 [PubMed]
Bredenoord AJ, Rösch T, Fockens P, Peroral endoscopic myotomy for achalasia. NEUROGASTROENT MOTIL 2014;26 (1):3-12 [PubMed]
de Bortoli N, Martinucci I, Savarino E, Bellini M, Bredenoord AJ, Franchi R, Bertani L, Furnari M, Savarino V, Blandizzi C, Marchi S, Proton pump inhibitor responders who are not confirmed as GERD patients with impedance and pH monitoring: who are they?. NEUROGASTROENT MOTIL 2014;26 (1):28-35 [PubMed]
de Bruyn JR, van Heeckeren R, Ponsioen CY, van den Brink GR, Löwenberg M, Bredenoord AJ, Frijstein G, D'Haens GR, Vitamin D deficiency in Crohn's disease and healthy controls: a prospective case-control study in the Netherlands. J CROHNS COLITIS 2014;8 (10):1267-1273 [PubMed]
de Groot NL, van Oijen MGH, Kessels K, Hemmink M, Weusten BLAM, Timmer R, Hazen WL, van Lelyveld N, Vermeijden JR, Curvers WL, Baak LC, Verburg R, Bosman JH, de Wijkerslooth LRH, de Rooij J, Venneman NG, Pennings M, van Hee K, Scheffer RCH, van Eijk RL, Meiland R, Siersema PD, Bredenoord AJ, Prediction scores or gastroenterologists' Gut Feeling for triaging patients that present with acute upper gastrointestinal bleeding. UNITED EUR GASTROENT 2014;2 (3):197-205 [PubMed]
de Groot NL, van Oijen MGH, Kessels K, Hemmink M, Weusten BLAM, Timmer R, Hazen WL, van Lelyveld N, Vermeijden RR, Curvers WL, Baak BC, Verburg R, Bosman JH, de Wijkerslooth LRH, de Rooij J, Venneman NG, Pennings M, van Hee K, Scheffer BCH, van Eijk RL, Meiland R, Siersema PD, Bredenoord AJ, Reassessment of the predictive value of the Forrest classification for peptic ulcer rebleeding and mortality: can classification be simplified?. ENDOSCOPY 2014;46 (1):46-52 [PubMed]
de Schepper HU, Kessing BF, Weijenborg PW, Oors JM, Smout AJPM, Bredenoord AJ, Impact of spatial resolution on results of esophageal high-resolution manometry. NEUROGASTROENT MOTIL 2014;26 (7):922-928 [PubMed]
de Schepper HU, Smout AJPM, Bredenoord AJ, Distal esophageal spasm evolving to achalasia in high resolution. CLIN GASTROENTEROL H 2014;12 (2):A25-A26 [PubMed]
Kessing BF, Bredenoord AJ, Smout AJPM, Objective manometric criteria for the rumination syndrome. AM J GASTROENTEROL 2014;109 (1):52-59 [PubMed]
Kessing BF, Bredenoord AJ, Smout AJPM, The Pathophysiology, Diagnosis and Treatment of Excessive Belching Symptoms. AM J GASTROENTEROL 2014;109 (8):1196-1203 [PubMed]
Kessing BF, Smout AJPM, Bennink RJ, Kraaijpoel N, Oors JM, Bredenoord AJ, Prucalopride decreases esophageal acid exposure and accelerates gastric emptying in healthy subjects. NEUROGASTROENT MOTIL 2014;26 (8):1079-1086 [PubMed]
Kessing BF, Smout AJPM, Bredenoord AJ, Current diagnosis and management of the rumination syndrome. J CLIN GASTROENTEROL 2014;48 (6):478-483 [PubMed]
Kessing BF, Weijenborg PW, Smout AJPM, Hillenius S, Bredenoord AJ, Water-perfused esophageal high-resolution manometry: normal values and validation. AM J PHYSIOL-GASTR L 2014;306 (6):G491-G495 [PubMed]
Saleh CMG, Bredenoord AJ, Utilization of esophageal function testing for the diagnosis of the rumination syndrome and belching disorders. GASTROINTEST ENDOSC CLIN N AM 2014;24 (4):633-642 [PubMed]
Sleiman PMA, Wang ML, Cianferoni A, Aceves S, Gonsalves N, Nadeau K, Bredenoord AJ, Furuta GT, Spergel JM, Hakonarson H, GWAS identifies four novel eosinophilic esophagitis loci. NAT COMMUN 2014;5:5593 [PubMed]
van Rhijn BD. Eosinophilic esophagitis studies on an emerging disease. S.l.: s.n.; 2014. 224p. ISBN 9789461088369 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Smout AJPM; copromotor(s): Bredenoord AJ, Verheij J)
van Rhijn BD, Curvers WL, Bergman JJGHM, Verheij J, Bredenoord AJ, Esophageal perforation during endoscopic removal of food impaction in eosinophilic esophagitis: stent well spent?. ENDOSCOPY 2014;46 (Suppl. 1 UCTN):E193-E194 [PubMed]
van Rhijn BD, Oors JM, Smout AJPM, Bredenoord AJ, Prevalence of esophageal motility abnormalities increases with longer disease duration in adult patients with eosinophilic esophagitis. NEUROGASTROENT MOTIL 2014;26 (9):1349-1355 [PubMed]
van Rhijn BD, Smout AJPM, Bredenoord AJ, Disease duration determines health-related quality of life in adult eosinophilic esophagitis patients. NEUROGASTROENT MOTIL 2014;26 (6):772-778 [PubMed]
van Rhijn BD, Warners MJ, Curvers WL, van Lent AU, Bekkali NL, Takkenberg RB, Kloek JJ, Bergman JJGHM, Fockens P, Bredenoord AJ, Evaluating the endoscopic reference score for eosinophilic esophagitis: moderate to substantial intra- and interobserver reliability. ENDOSCOPY 2014;46 (12):1049-1055 [PubMed]
van Rhijn BD, Weijenborg PW, Verheij J, van den Bergh Weerman MA, Verseijden C, van den Wijngaard RMJGJ, de Jonge WJ, Smout AJPM, Bredenoord AJ, Proton pump inhibitors partially restore mucosal integrity in patients with proton pump inhibitor-responsive esophageal eosinophilia but not eosinophilic esophagitis. CLIN GASTROENTEROL H 2014;12 (11):1815-23.e2 [PubMed]
Weijenborg PW, Kessing BF, Smout AJPM, Bredenoord AJ, Normal values for solid-state esophageal high-resolution manometry in a European population; an overview of all current metrics. NEUROGASTROENT MOTIL 2014;26 (5):654-659 [PubMed]
Weijenborg PW, Smout AJPM, Verseijden C, van Veen HA, Verheij J, de Jonge WJ, Bredenoord AJ, Hypersensitivity to acid is associated with impaired esophageal mucosal integrity in patients with gastroesophageal reflux disease with and without esophagitis. AM J PHYSIOL-GASTR L 2014;307 (3):G323-G329 [PubMed]
Bogte A, Bredenoord AJ, Oors J, Siersema PD, Smout AJPM, Normal values for esophageal high-resolution manometry. NEUROGASTROENT MOTIL 2013;25 (9):762-e579 [PubMed]
Bravi I, Woodland P, Gill RS, Al-Zinaty M, Bredenoord AJ, Sifrim D, Increased prandial air swallowing and postprandial gas-liquid reflux among patients refractory to proton pump inhibitor therapy. CLIN GASTROENTEROL H 2013;11 (7):784-789 [PubMed]
Bredenoord AJ, Management of belching, hiccups, and aerophagia. CLIN GASTROENTEROL H 2013;11 (1):6-12 [PubMed]
Bredenoord AJ, Bergman JJ, Fockens P, Aspiration of esophageal mucosa after esophageal stent removal. GASTROINTEST ENDOSC 2013;77 (3):496-497 [PubMed]
Bredenoord AJ, Pandolfino JE, Smout AJPM, Gastro-oesophageal reflux disease. LANCET 2013;381 (9881):1933-1942 [PubMed]
Bredenoord AJ, Smout AJPM, Advances in motility testing--current and novel approaches. NAT REV GASTRO HEPAT 2013;10 (8):463-472 [PubMed]
Bredenoord AJ, Smout AJPM, Association between reflux and symptoms during ambulatory reflux monitoring: pros and cons of existing methods. NEUROGASTROENT MOTIL 2013;25 (8):633-637 [PubMed]
de Groot NL. Risk stratification in upper gastrointestinal bleeding. s.l.: s.n.; 2013. 209p. ISBN 9789461085016 Proefschrift Universiteit Utrecht, DIGD. (Promotor(s): Siersema PD; copromotor(s): van Oijen MGH, Bredenoord AJ)
de Schepper HU, Bredenoord AJ, Smout AJPM, Chronische obstipatie en rectaal functieonderzoek. NED TIJDSCHR GENEESKD 2013;157 (8):A5976 [PubMed]
de Schepper HU, Smout AJPM, Bredenoord AJ, An unusual cause of Dysphagia. CLIN GASTROENTEROL H 2013;11 (9):A20 [PubMed]
Emmanuel A, Quigley EMM, Simrén M, Feng Y, Müller-Lissner S, Urbain D, Tack J, Bredenoord AJ, Sabaté JM, Yiannakou Y, Andresen V, Cuomo R, Rey E, Gryp RS, Vandeplassche L, Solomon D, Factors affecting satisfaction with treatment in European women with chronic constipation: An internet survey. UNITED EUR GASTROENT 2013;1 (5):375-384 [PubMed]
Griffin SM, Robertson AGN, Bredenoord AJ, Brownlee IA, Stovold R, Brodlie M, Forrest I, Dark JH, Pearson JP, Ward C, Aspiration and allograft injury secondary to gastroesophageal reflux occur in the immediate post-lung transplantation period (prospective clinical trial). ANN SURG 2013;258 (5):705-11; discussion 711-2 [PubMed]
Gyawali CP, Bredenoord AJ, Conklin JL, Fox M, Pandolfino JE, Peters JH, Roman S, Staiano A, Vaezi MF, Esophageal high resolution manometry in a community practice. NEUROGASTROENT MOTIL 2013;25 (9):776-777 [PubMed]
Gyawali CP, Bredenoord AJ, Conklin JL, Fox M, Pandolfino JE, Peters JH, Roman S, Staiano A, Vaezi MF, Evaluation of esophageal motor function in clinical practice. NEUROGASTROENT MOTIL 2013;25 (2):99-133 [PubMed]
Hemmink GJM, Alvarez Herrero L, Bogte A, Bredenoord AJ, Bergman JJ, Smout AJPM, Weusten BLAM, Esophageal motility and impedance characteristics in patients with Barrett's esophagus before and after radiofrequency ablation. EUR J GASTROEN HEPAT 2013;25 (9):1024-1032 [PubMed]
Kessing BF, Broeders JAJL, Vinke N, Schijven MP, Hazebroek EJ, Broeders IAMJ, Bredenoord AJ, Smout AJPM, Gas-related symptoms after antireflux surgery. SURG ENDOSC 2013;27 (10):3739-3747 [PubMed]
van der Pol RJ, Benninga MA, Bredenoord AJ, Kindermann A, Intramural pseudodiverticulosis of the esophagus: a case report. EUR J PEDIATR 2013;172 (12):1697-1699 [PubMed]
van Rhijn BD, Kessing BF, Smout AJPM, Bredenoord AJ, Oesophageal baseline impedance values are decreased in patients with eosinophilic oesophagitis. UNITED EUR GASTROENT 2013;1 (4):242-248 [PubMed]
van Rhijn BD, van Ree R, Versteeg SA, Vlieg-Boerstra BJ, Sprikkelman AB, Terreehorst I, Smout AJPM, Bredenoord AJ, Birch pollen sensitization with cross-reactivity to food allergens predominates in adults with eosinophilic esophagitis. ALLERGY 2013;68 (11):1475-1481 [PubMed]
van Rhijn BD, Verheij J, Smout AJPM, Bredenoord AJ, Rapidly increasing incidence of eosinophilic esophagitis in a large cohort. NEUROGASTROENT MOTIL 2013;25 (1):47-52.e5 [PubMed]
Verlaan T, Rohof WO, Bredenoord AJ, Eberl S, Rösch T, Fockens P, Effect of peroral endoscopic myotomy on esophagogastric junction physiology in patients with achalasia. GASTROINTEST ENDOSC 2013;78 (1):39-44 [PubMed]
von Renteln D, Fuchs KH, Fockens P, Bauerfeind P, Vassiliou MC, Werner YB, Fried G, Breithaupt W, Heinrich H, Bredenoord AJ, Kersten JF, Verlaan T, Trevisonno M, Rösch T, Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study. GASTROENTEROLOGY 2013;145 (2):309-11.e1-3 [PubMed]
Weijenborg PW, Bredenoord AJ, How reflux causes symptoms: reflux perception in gastroesophageal reflux disease. BEST PRACT RES CL GA 2013;27 (3):353-364 [PubMed]
Weijenborg PW, Rohof WOA, Akkermans LMA, Verheij J, Smout AJPM, Bredenoord AJ, Electrical tissue impedance spectroscopy: a novel device to measure esophageal mucosal integrity changes during endoscopy. NEUROGASTROENT MOTIL 2013;25 (7):574-8, e457-8 [PubMed]
Bogte A, Bredenoord AJ, Oors J, Siersema PD, Smout AJPM, Relationship between esophageal contraction patterns and clearance of swallowed liquid and solid boluses in healthy controls and patients with dysphagia. NEUROGASTROENT MOTIL 2012;24 (8):e364-e372 [PubMed]
Bredenoord AJ, Mechanisms of Reflux Perception in Gastroesophageal Reflux Disease: A Review. AM J GASTROENTEROL 2012;107 (1):8-15 [PubMed]
Bredenoord AJ, Fox M, Kahrilas PJ, Pandolfino JE, Schwizer W, Smout AJPM [Contributors: Conklin JL, Cook IJ, Gyawali CP, Hebbard G, Holloway RH, Ke M, Keller J, Mittal RK, Peters J, Richter J, Roman S, Rommel N, Sifrim D, Tutuian R, Valdovinos M, Vela MF, Zerbib F]] , Chicago classification criteria of esophageal motility disorders defined in high resolution esophageal pressure topography. NEUROGASTROENT MOTIL 2012;24 (1):57-65 [PubMed]
Bredenoord AJ, Hebbard GS, Technical aspects of clinical high-resolution manometry studies. NEUROGASTROENT MOTIL 2012;24 (1):5-10 [PubMed]
Broeders JA, Bredenoord AJ, Hazebroek EJ, Broeders IA, Gooszen HG, Smout AJ, Reflux and Belching After 270 Degree Versus 360 Degree Laparoscopic Posterior Fundoplication. ANN SURG 2012;255 (1):59-65 [PubMed]
de Groot NL, Bosman JH, Siersema PD, van Oijen MGH, Bredenoord AJ, Admission time is associated with outcome of upper gastrointestinal bleeding: results of a multicentre prospective cohort study. ALIMENT PHARM THER 2012;36 (5):477-484 [PubMed]
Kessing BF, Bredenoord AJ, Smout AJPM, Mechanisms of gastric and supragastric belching: a study using concurrent high-resolution manometry and impedance monitoring. NEUROGASTROENT MOTIL 2012;24 (12):e573-e579 [PubMed]
Kessing BF, Bredenoord AJ, Velosa M, Smout AJPM, Supragastric belches are the main determinants of troublesome belching symptoms in patients with gastro-oesophageal reflux disease. ALIMENT PHARM THER 2012;35 (9):1073-1079 [PubMed]
Kessing BF, Smout AJPM, Bredenoord AJ, Clinical applications of esophageal impedance monitoring and high-resolution manometry. CURR GASTROENTEROL REP 2012;14 (3):197-205 [PubMed]
Kessing BF, Weijenborg PW, Bredenoord AJ, Smout AJPM, Baseline Impedance Levels and Structural and Functional Integrity of the Esophageal Mucosa: Is Acid Still the Only Player? Response. AM J GASTROENTEROL 2012;107 (7):1104-1105 [PubMed]
van Rhijn BD, Smout AJPM, Bredenoord AJ, Eosinofiele oesofagitis: een vaak gemiste oorzaak van dysfagie. NED TIJDSCHR GENEESKD 2012;156 (23):A4716 [PubMed]
Weijenborg PW, Cremonini F, Smout AJPM, Bredenoord AJ, PPI therapy is equally effective in well-defined non-erosive reflux disease and in reflux esophagitis: a meta-analysis. NEUROGASTROENT MOTIL 2012;24 (8):747-+ [PubMed]
Weijenborg PW, Cremonini F, Smout AJPM, Bredenoord AJ, Response to letter It is time to plan clinical trials on true NERD patients'. NEUROGASTROENT MOTIL 2012;24 (9):887 [PubMed]
Bogte A, Bredenoord AJ, Oors J, Siersema PD, Smout AJPM, Reproducibility of esophageal high-resolution manometry. NEUROGASTROENT MOTIL 2011;23 (7):e271-e276 [PubMed]
Bredenoord AJ, Belching, aerophagia, and rumination. J PEDIATR GASTR NUTR 2011;53 (Suppl. 2):S19-S21 [PubMed]
Bredenoord AJ, Jafari J, Kadri S, Simcock DE, Sifrim D, Preston SL, Case report: achalasia-like dysmotility secondary to oesophageal involvement of sarcoidosis. GUT 2011;60 (2):153-155 [PubMed]
Broeders JA, Draaisma WA, Bredenoord AJ, Smout AJ, Broeders IA, Gooszen HG, Impact of symptom-reflux association analysis on long-term outcome after Nissen fundoplication. BRIT J SURG 2011;98 (2):247-254 [PubMed]
Broeders JAJL, Bredenoord AJ, Hazebroek EJ, Broeders IAMJ, Gooszen HG, Smout AJPM, Effects of anti-reflux surgery on weakly acidic reflux and belching. GUT 2011;60 (4):435-441 [PubMed]
Hemmink GJM, Bredenoord AJ, Aanen MC, Weusten BLAM, Timmer R, Smout AJPM, Computer analysis of 24-h esophageal impedance signals. SCAND J GASTROENTERO 2011;46 (3):271-276 [PubMed]
Kessing BF, Bredenoord AJ, Smout AJPM, Erroneous diagnosis of gastroesophageal reflux disease in achalasia. CLIN GASTROENTEROL H 2011;9 (12):1020-1024 [PubMed]
Kessing BF, Bredenoord AJ, Weijenborg PW, Hemmink GJM, Loots CM, Smout AJPM, Esophageal acid exposure decreases intraluminal baseline impedance levels. AM J GASTROENTEROL 2011;106 (12):2093-2097 [PubMed]
Kessing BF, Conchillo JM, Bredenoord AJ, Smout AJPM, Masclee AAM, Review article: the clinical relevance of transient lower oesophageal sphincter relaxations in gastro-oesophageal reflux disease. ALIMENT PHARM THER 2011;33 (6):650-661 [PubMed]
Bredenoord AJ, Excessive belching and aerophagia: two different disorders. DIS ESOPHAGUS 2010;23 (4):347-352 [PubMed]
Bredenoord AJ, New therapies for gastroesophageal reflux disease. MINERVA GASTROENTEROL DIETOL 2010;56 (2):129-138 [PubMed]
Bredenoord AJ, Smout AJ, Impaired health-related quality of life in patients with excessive supragastric belching. EUR J GASTROEN HEPAT 2010;22 (12):1420-1423 [PubMed]
Broeders JA, Draaisma WA, Bredenoord AJ, Smout AJ, Broeders IA, Gooszen HG, Long-term outcome of Nissen fundoplication in non-erosive and erosive gastro-oesophageal reflux disease. BRIT J SURG 2010;97 (6):845-852 [PubMed]
Hemmink GJM, ten Cate L, Bredenoord AJ, Timmer R, Weusten BLAM, Smout AJPM, Speech therapy in patients with excessive supragastric belching--a pilot study. NEUROGASTROENT MOTIL 2010;22 (1):24-8, e2-3 [PubMed]
Hemmink GJM, Weusten BLAM, Oors J, Bredenoord AJ, Timmer R, Smout AJPM, Ambulatory oesophageal pH monitoring: a comparison between antimony, ISFET, and glass pH electrodes. EUR J GASTROEN HEPAT 2010;22 (5):572-577 [PubMed]
Scheffer RCH, Bredenoord AJ, Hebbard GS, Smout AJPM, Samsom M, Effect of proximal gastric volume on hiatal hernia. NEUROGASTROENT MOTIL 2010;22 (5):552-6, e120 [PubMed]
Bredenoord AJ, Lesogaberan, a GABA(B) agonist for the potential treatment of gastroesophageal reflux disease. IDRUGS 2009;12 (9):576-584 [PubMed]
Bredenoord AJ, Hemmink GJM, Smout AJPM, Relationship between gastro-oesophageal reflux pattern and severity of mucosal damage. NEUROGASTROENT MOTIL 2009;21 (8):807-812 [PubMed]
Bredenoord AJ, Stolk MF, Al-Toma A, Unintentional video capsule bronchoscopy. EUR J GASTROEN HEPAT 2009;21 (5):593 [PubMed]
Broeders JA, Draaisma WA, Bredenoord AJ, de Vries DR, Rijnhart-de Jong HG, Smout AJ, Gooszen HG, Oesophageal acid hypersensitivity is not a contraindication to Nissen fundoplication. BRIT J SURG 2009;96 (9):1023-1030 [PubMed]
Broeders JA, Draaisma WA, de Vries DR, Bredenoord AJ, Smout AJ, Gooszen HG, The preoperative reflux pattern as prognostic indicator for long-term outcome after Nissen fundoplication. AM J GASTROENTEROL 2009;104 (8):1922-1930 [PubMed]
Broeders JA, Rijnhart-de Jong HG, Draaisma WA, Bredenoord AJ, Smout AJ, Gooszen HG, Ten-year outcome of laparoscopic and conventional nissen fundoplication: randomized clinical trial. ANN SURG 2009;250 (5):698-706 [PubMed]
de Winter BY, Bredenoord AJ, van Nassauw L, de Man JG, de Schepper HU, Timmermans JP, Pelckmans PA, Involvement of afferent neurons in the pathogenesis of endotoxin-induced ileus in mice: role of CGRP and TRPV1 receptors. EUR J PHARMACOL 2009;615 (1-3):177-184 [PubMed]
Hemmink GJM. New insights into aerophagia, belching and gastro-oesophageal reflux.. Utrecht: Gildeprint Drukkerijen, Enschede; 2009. 154p. ISBN 978-90-3935174-1 Proefschrift Universiteit Utrecht, Maag- darm- leverziekten, onderzoek in AMC-UvA. (Promotor(s): Smout AJPM; copromotor(s): Bredenoord AJ, Weusten BLAM)
Hemmink GJM, Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Does acute psychological stress increase perception of oesophageal acid?. NEUROGASTROENT MOTIL 2009;21 (10):1055-1e86 [PubMed]
Hemmink GJM, Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Supragastric belching in patients with reflux symptoms. AM J GASTROENTEROL 2009;104 (8):1992-1997 [PubMed]
Hemmink GJM, Weusten BLAM, Bredenoord AJ, Timmer R, Smout AJPM, Aerophagia: excessive air swallowing demonstrated by esophageal impedance monitoring. CLIN GASTROENTEROL H 2009;7 (10):1127-1129 [PubMed]
Hemmink GJM, Weusten BLAM, Bredenoord AJ, Timmer R, Smout AJPM, Increased swallowing frequency in GORD is likely to be caused by perception of reflux episodes. NEUROGASTROENT MOTIL 2009;21 (2):143-148 [PubMed]
Pandolfino JE, Fox MR, Bredenoord AJ, Kahrilas PJ, High-resolution manometry in clinical practice: utilizing pressure topography to classify oesophageal motility abnormalities. NEUROGASTROENT MOTIL 2009;21 (8):796-806 [PubMed]
Robertson AGN, Ward C, Pearson JP, Small T, Lordan J, Fisher AJ, Bredenoord AJ, Dark J, Griffin SM, Corris PA, Longitudinal changes in gastro-oesophageal reflux from 3 months to 6 months after lung transplantation. THORAX 2009;64 (11):1005-1007 [PubMed]
van Werkum JW, ten Berg JM, Bredenoord AJ, Proton pump inhibitors and clopidogrel: a difficult dilemma. AM HEART J 2009;157 (6):e43; author reply e45 [PubMed]
Aanen MA. Studies on gastroesophageal reflux disease.. Utrecht: Gildeprint Drukkerijen BV, Enschede; 2008. 140p. ISBN 978-90-393-48260 Proefschrift Universiteit Utrecht, Maag- darm- leverziekten, onderzoek in AMC-UvA. (Promotor(s): Smout AJPM; copromotor(s): Bredenoord AJ, Numans ME)
Aanen MC, Bredenoord AJ, Numans ME, Samson M, Smout AJPM, Reproducibility of symptom association analysis in ambulatory reflux monitoring. AM J GASTROENTEROL 2008;103 (9):2200-2208 [PubMed]
Aanen MC, Bredenoord AJ, Samsom M, Smout AJPM, Reliability of oesophageal pH recording for the detection of gastro-oesophageal reflux. SCAND J GASTROENTERO 2008;43 (12):1442-1447 [PubMed]
Bogte A, Bredenoord AJ, Smout AJPM, Diagnostic yield of oesophageal pH monitoring in patients with chronic unexplained cough. SCAND J GASTROENTERO 2008;43 (1):13-19 [PubMed]
Bredenoord AJ, Impedance-pH monitoring: new standard for measuring gastro-oesophageal reflux. NEUROGASTROENT MOTIL 2008;20 (5):434-439 [PubMed]
Bredenoord AJ, Draaisma WA, Weusten BLAM, Gooszen HG, Smout AJPM, Mechanisms of acid, weakly acidic and gas reflux after anti-reflux surgery. GUT 2008;57 (2):161-166 [PubMed]
Bredenoord AJ, Onaca MG, van Ramshorst B, Biesma DH, Sigmoïdcarcinoom als langetermijncomplicatie na ureterosigmoïdostomie. NED TIJDSCHR GENEESKD 2008;152 (4):213-215 [PubMed]
Bredenoord AJ, Smout AJ, Esophageal motility testing: impedance-based transit measurement and high-resolution manometry. GASTROENTEROL CLIN N 2008;37 (4):775-91, vii [PubMed]
Bredenoord AJ, Smout AJ, Refractory gastrooesophageal reflux disease. EUR J GASTROEN HEPAT 2008;20 (3):217-223 [PubMed]
Bredenoord AJ, Smout AJPM, High-resolution manometry. DIGEST LIVER DIS 2008;40 (3):174-181 [PubMed]
Bredenoord AJ, Smout AJPM, Therapieresistentie van gastro-oesofageale refluxklachten: zure reflux, niet-zure reflux of geen reflux. NED TIJDSCHR GENEESKD 2008;152 (47):2548-2552 [PubMed]
Fox MR, Bredenoord AJ, Oesophageal high-resolution manometry: moving from research into clinical practice. GUT 2008;57 (3):405-423 [PubMed]
Hemmink GJM, Bredenoord AJ, Weusten BLAM, Monkelbaan JF, Timmer R, Smout AJPM, Esophageal pH-impedance monitoring in patients with therapy-resistant reflux symptoms: 'on' or 'off' proton pump inhibitor?. AM J GASTROENTEROL 2008;103 (10):2446-2453 [PubMed]
Bredenoord AJ, Dent J, Proton pump inhibitor-therapy refractory gastro-oesophageal reflux disease patients, who are they?. GUT 2007;56 (4):593-594 [PubMed]
Bredenoord AJ, Smout AJ, High-resolution manometry of the esophagus: more than a colorful view on esophageal motility?. EXPERT REV GASTROENT 2007;1 (1):61-69 [PubMed]
Bredenoord AJ, Smout AJPM, Physiologic and pathologic belching. CLIN GASTROENTEROL H 2007;5 (7):772-775 [PubMed]
Bredenoord AJ, Tutuian R, Smout AJPM, Castell DO, Technology review: Esophageal impedance monitoring. AM J GASTROENTEROL 2007;102 (1):187-194 [PubMed]
Conchillo JM, Selimah M, Bredenoord AJ, Samsom M, Smout AJPM, Air swallowing, belching, acid and non-acid reflux in patients with functional dyspepsia. ALIMENT PHARM THER 2007;25 (8):965-971 [PubMed]
Aanen MC, Bredenoord AJ, Samsom M, Smout AJPM, The gastro-oesophageal common cavity revisited. NEUROGASTROENT MOTIL 2006;18 (12):1056-1061 [PubMed]
Aanen MC, Bredenoord AJ, Smout AJPM, Effect of dietary sodium chloride on gastro-oesophageal reflux: a randomized controlled trial. SCAND J GASTROENTERO 2006;41 (10):1141-1146 [PubMed]
Bredenoord AJ. Gastro-oesophageal reflux and belching, revisited.. Utrecht: Febodruk BV Enschede; 2006. 266p. ISBN 978-90-393-4309-8 Proefschrift Universiteit van Utrecht, Maag- darm- leverziekten, onderzoek in AMC-UvA. (Promotor(s): Smout AJPM; copromotor(s): Weusten BLAM, Timmer R)
Bredenoord AJ, Baron A, Smout AJPM, Symptomatic gastro-oesophageal reflux in a patient with achlorhydria. GUT 2006;55 (7):1054-1055 [PubMed]
Bredenoord AJ, Smout AJ, Acid perfusion test: a useful test for evaluating esophageal acid sensitivity?. DIGEST DIS SCI 2006;51 (5):873 [PubMed]
Bredenoord AJ, Weusten BLAM, Curvers WL, Timmer R, Smout AJPM, Determinants of perception of heartburn and regurgitation. GUT 2006;55 (3):313-318 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Conchillo JM, Smout AJPM, Addition of esophageal impedance monitoring to pH monitoring increases the yield of symptom association analysis in patients off PPI therapy. AM J GASTROENTEROL 2006;101 (3):453-459 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Air swallowing, belching, and reflux in patients with gastroesophageal reflux disease. AM J GASTROENTEROL 2006;101 (8):1721-1726 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Characteristics of gastroesophageal reflux in symptomatic patients with and without excessive esophageal acid exposure. AM J GASTROENTEROL 2006;101 (11):2470-2475 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Gastro-oesophageal reflux of liquids and gas during transient lower oesophageal sphincter relaxations. NEUROGASTROENT MOTIL 2006;18 (10):888-893 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Intermittent spatial separation of diaphragm and lower esophageal sphincter favors acidic and weakly acidic reflux. GASTROENTEROLOGY 2006;130 (2):334-340 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Psychological factors affect the frequency of belching in patients with aerophagia. AM J GASTROENTEROL 2006;101 (12):2777-2781 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Vandevoorde RRA, Smout AJPM, Boeren (ructus). NED TIJDSCHR GENEESKD 2006;150 (25):1385-1389 [PubMed]
Chitkara DK, Bredenoord AJ, Talley NJ, Whitehead WE, Aerophagia and rumination: recognition and therapy. CURR TREAT OPTIONS GASTROENTEROL 2006;9 (4):305-313 [PubMed]
Conchillo JM, Selimah M, Bredenoord AJ, Samsom M, Smout AJPM, Assessment of oesophageal emptying in achalasia patients by intraluminal impedance monitoring. NEUROGASTROENT MOTIL 2006;18 (11):971-977 [PubMed]
Bredenoord AJ, Smout AJPM, Oesophageal pH has a power-law distribution in control and gastro-oesophageal reflux disease subjects. ALIMENT PHARM THER 2005;21 (7):917; author reply 918 [PubMed]
Bredenoord AJ, Weusten BLAM, Smout AJPM, Symptom association analysis in ambulatory gastro-oesophageal reflux monitoring. GUT 2005;54 (12):1810-1817 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Akkermans LMA, Smout AJPM, Relationships between air swallowing, intragastric air, belching and gastro-oesophageal reflux. NEUROGASTROENT MOTIL 2005;17 (3):341-347 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Reproducibility of multichannel intraluminal electrical impedance monitoring of gastroesophageal reflux. AM J GASTROENTEROL 2005;100 (2):265-269 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Sleeve sensor versus high-resolution manometry for the detection of transient lower esophageal sphincter relaxations. AM J PHYSIOL-GASTR L 2005;288 (6):G1190-G1194 [PubMed]
Chitkara DK, Bredenoord AJ, Bredenood AJ, Wang M, Rucker MJ, Talley NJ, Aerophagia in children: characterization of a functional gastrointestinal disorder. NEUROGASTROENT MOTIL 2005;17 (4):518-522 [PubMed]
Chitkara DK, Bredenoord AJ, Rucker MJ, Talley NJ, Aerophagia in adults: a comparison with functional dyspepsia. ALIMENT PHARM THER 2005;22 (9):855-858 [PubMed]
de Winter BY, van Nassauw L, de Man JG, de Jonge F, Bredenoord AJ, Seerden TC, Herman AG, Timmermans JP, Pelckmans PA, Role of oxidative stress in the pathogenesis of septic ileus in mice. NEUROGASTROENT MOTIL 2005;17 (2):251-261 [PubMed]
Bredenoord AJ, Weusten BLAM, Carmagnola S, Smout AJPM, Double-peaked high-pressure zone at the esophagogastric junction in controls and in patients with a hiatal hernia: a study using high-resolution manometry. DIGEST DIS SCI 2004;49 (7-8):1128-1135 [PubMed]
Bredenoord AJ, Weusten BLAM, Sifrim D, Timmer R, Smout AJPM, Aerophagia, gastric, and supragastric belching: a study using intraluminal electrical impedance monitoring. GUT 2004;53 (11):1561-1565 [PubMed]
Bredenoord AJ, Weusten BLAM, Timmer R, Smout AJPM, Minimum sample frequency for multichannel intraluminal impedance measurement of the oesophagus. NEUROGASTROENT MOTIL 2004;16 (6):713-719 [PubMed]
Chitkara DK, Bredenoord AJ, Cremonini F, Delgado-Aros S, Smoot RL, El-Youssef M, Freese D, Camilleri M, The role of pelvic floor dysfunction and slow colonic transit in adolescents with refractory constipation. AM J GASTROENTEROL 2004;99 (8):1579-1584 [PubMed]
Bredenoord AJ, Chial HJ, Camilleri M, Mullan BP, Murray JA, Gastric accommodation and emptying in evaluation of patients with upper gastrointestinal symptoms. CLIN GASTROENTEROL H 2003;1 (4):264-272 [PubMed]
Bredenoord AJ, Weusten BLAM, Roelofs JMM, Smout AJPM, The gastro-oesophageal pressure inversion point revisited. SCAND J GASTROENTERO 2003;38 (8):812-818 [PubMed]
Chitkara DK, Delgado-Aros S, Bredenoord AJ, Cremonini F, El-Youssef M, Freese D, Camilleri M, Functional dyspepsia, upper gastrointestinal symptoms, and transit in children. J PEDIATR-US 2003;143 (5):609-613 [PubMed]
Delgado-Aros S, Cremonini F, Bredenoord AJ, Camilleri M, Systematic review and meta-analysis: does gall-bladder ejection fraction on cholecystokinin cholescintigraphy predict outcome after cholecystectomy in suspected functional biliary pain?. ALIMENT PHARM THER 2003;18 (2):167-174 [PubMed]
de Winter BY, Bredenoord AJ, de Man JG, Moreels TG, Herman AG, Pelckmans PA, Effect of inhibition of inducible nitric oxide synthase and guanylyl cyclase on endotoxin-induced delay in gastric emptying and intestinal transit in mice. SHOCK 2002;18 (2):125-131 [PubMed]
Key publications

Bredenoord AJ, Pandolfino JE, Smout AJPM, Gastro-oesophageal reflux disease. LANCET 2013;381 (9881):1933-1942 [PubMed]
Bredenoord AJ, Fox M, Kahrilas PJ, Pandolfino JE, Schwizer W, Smout AJPM [Contributors: Conklin JL, Cook IJ, Gyawali CP, Hebbard G, Holloway RH, Ke M, Keller J, Mittal RK, Peters J, Richter J, Roman S, Rommel N, Sifrim D, Tutuian R, Valdovinos M, Vela MF, Zerbib F]] , Chicago classification criteria of esophageal motility disorders defined in high resolution esophageal pressure topography. NEUROGASTROENT MOTIL 2012;24 (1):57-65 [PubMed]
Smout AJPM, Bredenoord AJ, GERD: A challenge to our view of reflux oesophagitis pathogenesis. NAT REV GASTRO HEPAT 2016;13 (9):504-505 [PubMed]
van Rhijn BD, Vlieg-Boerstra BJ, Versteeg SA, Akkerdaas JH, van Ree R, Terreehorst I, Sprikkelman AB, Verheij J, Smout AJPM, Bredenoord AJ, Evaluation of allergen-microarray-guided dietary intervention as treatment of eosinophilic esophagitis. J ALLERGY CLIN IMMUN 2015;136 (4):1095-7.e3 [PubMed]
van Rhijn BD, Verheij J, van den Bergh Weerman MA, Verseijden C, van den Wijngaard RMJGJ, de Jonge WJ, Smout AJPM, Bredenoord AJ, Histological Response to Fluticasone Propionate in Patients With Eosinophilic Esophagitis Is Associated With Improved Functional Esophageal Mucosal Integrity. AM J GASTROENTEROL 2015;110 (9):1289-1297 [PubMed]


All Publications

Curriculum Vitae

Dr Bredenoord volgde zijn opleiding tot MDL-arts in het Antonius Ziekenhuis Nieuwegein, het Barts and the London Hospital in Londen en in het AMC Amsterdam. Hij is al meer dan 10 jaar actief op het gebied van goedaardige ziekten van de slokdarm zoals achalasie, refluxziekte en eosinofiele oesofagitis.  In zijn proefschrift (2006) beschrijft hij nieuwe technieken om reflux en motiliteit te meten in de slokdarm. Er is inmiddels geen andere arts in Nederland die door zoveel patienten met benigne slokdarmziekten wordt bezocht. In zijn onderzoek probeert hij steeds een brug te leggen tussen kennis in het ziekenhuis en onderzoek in het laboratorium. Er wordt zowel pathofysiologisch, diagnostisch als therapeutisch onderzoek uitgevoerd door hem en zijn team. Hij is auteur van meer dan 100 artikelen, boeken, hoofdstukken en richtlijnen op dit gebied en organisator van meerdere wetenschappelijke en klinische cursussen in Europa, Azië en de VS.

 

Dr Bredenoord was trained as a gastroenterologist in the Antonius Ziekenhuis Nieuwegein, the Barts and the London Hospital in Londen and the AMC Amsterdam. He is active for over 10 years in the field of benign esophageal diseases such as achalasia, reflux disease and eosinophilic esophagitis. In his PhD thesis (2006) he described new techniques to measure reflux and motility patterns in the esophagus. His clinic now hosts the largest population of patients with benign esophageal diseases in the Netherlands. In his scientific research he tries to make a bridge between clinical knowledge and science. Both pathophysiological, diagnostic and therapeutic studies are being performed. He is author of over 100 articles, books, chapters and guidelines in his field and organisor of several scientific and clinical conferences in Europe, Asia and the USA.

Research programmes

Neurogastroenterology and Motility: Esophageal diseases

The Esophagus Center of the AMC is the largest referral clinic for non-malignant esophageal disorders in the Netherlands. We combine an special clinical expertise with a large number of trials and studies focussed on finding underlying pathophysiology, assessment of new diagnostic techniques and improved treatments. Three diseases are central: gastroesophageal reflux disease (GERD), eosinophilic esophagitis (EoE) and achalasia. Collaborations with interventional endoscopists (Prof P Fockens), surgeons (Dr M Schijven en Dr M van Berge Henegouwen), pathologists (Dr J Verheij), pediatricians (Prof M Benninga) and basic scientists (Prof W de Jonge and dr R van den Wijngaard) are essential for the great results of our group.

Faculty
Dr. A.J. Bredenoord

PhD Students
Drs. F. B. van Hoeij
R.A.B. Oude Nijhuis
Drs. F.A.M. Ponds
W.E. de Rooij
M.J. Warners
Drs. A. Bogte (Universiteit Utrecht)
C.M.G. Saleh

Prof. dr. A.J.P.M. Smout (Clinical Neurogastroenterology and Motility)

Prof. dr. P. Fockens MD (Advanced diagnostic and therapeutic gastrointestinal endoscopy in GI oncology (CRC and HPB) and neurogastroenterology)

Other research related activities
  • Membership of editorial board / Editorship, NEUROGASTROENTEROLOGY AND MOTILITY
  • Membership of editorial board / Editorship, GUT
Current research funding
  • Dr. Falk Pharma GmbH
  • EndoStim Inc.
  • Fonds NUTS-OHRA
  • Steigerwald Arzneimittelwerk GmbH
  • Stichting AMC Foundation (Vrijgesteld)