• Principal Investigator
  • Male

Prof. dr. R.M.A. de Bie

Position: Professor
Main activities: Patient care, Research, Teaching
Specialisation: Neurology, Movement Disorders
foto R.M.A. de Bie is one of the AMC Principal Investigators
Focus of research:

Improving the treatment of Movement Disorders.

Parkinson's disease; medication, deep brain stimulation (DBS), and continuous Intrajejunal Levodopa Infusion.

We conduct (multicenter) clinical trials and cohort studies.

AMC themes: Neurological & Psychiatric Disorders
Departments: Neurology
Avan A, de Bie RMA, Hoogenraad TU, Wilson's Disease Should Be Treated with Zinc rather than Trientine or Penicillamine. NEUROPEDIATRICS 2017;48 (5):394-395 [PubMed]
Holewijn RA, Verbaan D, de Bie RMA, Schuurman PR, General Anesthesia versus Local Anesthesia in StereotaXY (GALAXY) for Parkinson's disease: study protocol for a randomized controlled trial. TRIALS 2017;18 (1):417 [PubMed]
Hoogland J, Boel JA, de Bie RMA, Geskus RB, Schmand BA, Dalrymple-Alford JC, Marras C, Adler CH, Goldman JG, Tröster AI, Burn DJ, Litvan I, Geurtsen GJ, Mild Cognitive Impairment as a Risk Factor for Parkinson's Disease Dementia. MOVEMENT DISORD 2017;32 (7):1056-1065 [PubMed]
Mansouri A, Taslimi S, Badhiwala JH, Witiw CD, Nassiri F, Odekerken VJJ, de Bie RMA, Kalia SK, Hodaie M, Munhoz RP, Fasano A, Lozano AM, Deep brain stimulation for Parkinson's disease: meta-analysis of results of randomized trials at varying lengths of follow-up. J NEUROSURG 2017;ahead of print [PubMed]
van den Noort JC, Verhagen R, van Dijk KJ, Veltink PH, Vos MCPM, de Bie RMA, Bour LJ, Heida CT, Quantification of Hand Motor Symptoms in Parkinson's Disease: A Proof-of-Principle Study Using Inertial and Force Sensors. ANN BIOMED ENG 2017;45 (10):2423-2436 [PubMed]
Witte LP, Odekerken VJJ, Boel JA, Schuurman PR, Gerbrandy-Schreuders LC, de Bie RMA, Does deep brain stimulation improve lower urinary tract symptoms in Parkinson's disease?. NEUROUROL URODYNAM 2017;ahead of print [PubMed]
Boel JA, Odekerken VJJ, Geurtsen GJ, Schmand BA, Cath DC, Figee M, van den Munckhof P, de Haan RJ, Schuurman PR, de Bie RMA [Contributors: Odekerken VJJ, Boel JA, van Laar T, van Dijk JMC, Mosch A, Hoffmann CFE, Nijssen PCG, Beute GN, van Vugt JPP, Lenders MWPM, Contarino MF, Bour LJ, van den Munckhof P, Geurtsen GJ, Schmand BA, de Haan RJ, Schuurman PR, de Bie RMA]] , Psychiatric and social outcome after deep brain stimulation for advanced Parkinson's disease. MOVEMENT DISORD 2016;31 (3):409-413 [PubMed]
Boel JA, Odekerken VJJ, Schmand BA, Geurtsen GJ, Cath DC, Figee M, van den Munckhof P, de Haan RJ, Schuurman PR, de Bie RMA [Contributors: Odekerken VJJ, Boel JA, van Laar T, van Dijk JMC, Mosch A, Hoffmann CFE, Nijssen PCG, van Asseldonk T, Beute GN, van Vugt JPP, Lenders MWPM, Fiorella Contarino M, Bour LJ, Geurtsen GJ, van den Munckhof P, Schmand BA, de Haan RJ, Schuurman PR, de Bie RMA]] , Cognitive and psychiatric outcome 3 years after globus pallidus pars interna or subthalamic nucleus deep brain stimulation for Parkinson's disease. PARKINSONISM RELAT D 2016;33:90-95 [PubMed]
Bot M, Bour L, de Bie RM, Contarino MF, Schuurman PR, van den Munckhof P, Can We Rely on Susceptibility-Weighted Imaging for Subthalamic Nucleus Identification in Deep Brain Stimulation Surgery?. NEUROSURGERY 2016;78 (3):353-360 [PubMed]
Lesage S, Drouet V, Majounie E, Deramecourt V, Jacoupy M, Nicolas A, Cormier-Dequaire F, Hassoun SM, Pujol C, Ciura S, Erpapazoglou Z, Usenko T, Maurage CA, Sahbatou M, Liebau S, Ding J, Bilgic B, Emre M, Erginel-Unaltuna N, Guven G, Tison F, Tranchant C, Vidailhet M, Corvol JC, Krack P, Leutenegger AL, Nalls MA, Hernandez DG, Heutink P, Gibbs JR, Hardy J, Wood NW, Gasser T, Durr A, Deleuze JF, Tazir M, Destée A, Lohmann E, Kabashi E, Singleton A, Corti O, Brice A [Contributors: Lesage S, Tison F, Vidailhet M, Corvol JC, Agid Y, Anheim M, Bonnet AM, Borg M, Broussolle E, Damier P, Destée A, Dürr A, Durif F, Krack P, Klebe S, Lohmann E, Martinez M, Pollak P, Rascol O, Tranchant C, Vérin M, Viallet F, Brice A, Majounie E, Corvol JC, Nalls MA, Hernandez DG, Gibbs JR, Arepalli S, Barker RA, Ben-Shlomo Y, Berg D, Bettella F, Bhatia K, de Bie RMA, Biffi A, Bloem BR, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Counsell C, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Dong J, Durif F, Edkins S, Escott-Price V, Evans JR, Foltynie T, Gao J, Gardner M, Goate A, Gray E, Guerreiro R, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holmans P, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Kilarski LL, Jansen IE, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, Lubbe S, Lungu C, Martinez M, Mätzler W, McNeill A, Moorby C, Moore M, Morrison KE, Mudanohwo E, O'Sullivan SS, Owen MJ, Pearson J, Perlmutter JS, Pétursson H, Plagnol V, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Saad M, Simón-Sánchez J, Sawcer S, Schapira A, Scheffer H, Schulte C, Sharma M, Shaw K, Sheerin UM, Shoulson I, Shulman J, Sidransky E, Spencer CCA, Stefánsson H, Stefánsson K, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Walker R, van de Warrenburg B, Wickremaratchi M, Williams-Gray CH, Winder-Rhodes S, Wurster I, Williams N, Morris HR, Heutink P, Hardy J, Wood NW, Gasser T, Singleton AB]] , Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy. AM J HUM GENET 2016;98 (3):500-513 [PubMed]
Odekerken VJJ. Deep brain stimulation of the subthalamic nucleus and globus internus for advanced Parkinson's disease. S.l.: s.n.; 2016. 186p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Schaik IN, Schuurman PR; copromotor(s): de Bie RMA, van den Munckhof P)
Odekerken VJJ, Boel JA, Schmand BA, de Haan RJ, Figee M, van den Munckhof P, Schuurman PR, de Bie RMA [Contributors: de Bie RMA, Bour L, Contarino MF, de Haan RJ, Iwan M, Mink MSJ, van den Munckhof P, Odekerken VJJ , Postma M, Schmand BA, Scholten MN, Schuurman PR, van Laar T, van Dijk JMC, Hoffmann CFE, Mosch A, Beute GN, Nijssen PCG, van Asseldonk T, Lenders MWPM, van Vugt JPP]] , GPi vs STN deep brain stimulation for Parkinson disease: Three-year follow-up. NEUROLOGY 2016;86 (8):755-761 [PubMed]
Sidiropoulos C, LeWitt PA, Odekerken VJJ, Schuurman PR, de Bie RMA, GPi vs STN deep brain stimulation for Parkinson disease: Three-year follow-up. NEUROLOGY 2016;87 (7):745-746 [PubMed]
Smit JV, Janssen MLF, Engelhard M, de Bie RMA, Schuurman PR, Contarino MF, Mosch A, Temel Y, Stokroos RJ, The impact of deep brain stimulation on tinnitus. SURG NEUROL INT 2016;7 (Suppl 35):S848-S854 [PubMed]
Velseboer DC, de Bie RMA, Wieske L, Evans JR, Mason SL, Foltynie T, Schmand B, de Haan RJ, Post B, Barker RA, Williams-Gray CH, Development and external validation of a prognostic model in newly diagnosed Parkinson disease. NEUROLOGY 2016;86 (11):986-993 [PubMed]
Verhagen R, Schuurman PR, van den Munckhof P, Contarino MF, de Bie RMA, Bour LJ, Comparative study of microelectrode recording-based STN location and MRI-based STN location in low to ultra-high field (7.0 T) T2-weigthed MRI images. J NEURAL ENG 2016;13 (6):066009 [PubMed]
Bour LJ, Lourens MAJ, Verhagen R, de Bie RMA, van den Munckhof P, Schuurman PR, Contarino MF, Directional Recording of Subthalamic Spectral Power Densities in Parkinson's Disease and the Effect of Steering Deep Brain Stimulation. BRAIN STIMUL 2015;8 (4):730-741 [PubMed]
Broeders M. Cognitive change in Parkinson's disease. S.l.: s.n.; 2015. 186p. ISBN 978-94-6259-589-7 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Schmand BA, Ridderinkhof KR; copromotor(s): de Bie RMA)
Contarino MF, Bour LJ, Schuurman PR, Blok ER, Odekerken VJJ, van den Munckhof P, de Bie RMA, van Rootselaar AF, Thalamic deep brain stimulation for orthostatic tremor: Clinical and neurophysiological correlates. PARKINSONISM RELAT D 2015;21 (8):1005-1007 [PubMed]
Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, Teumer A, Yu K, Marques-Vidal P, Rawal R, Manichaikul A, Wojczynski MK, Vink JM, Zhao JH, Burlutsky G, Lahti J, Mikkilä V, Lemaitre RN, Eriksson J, Musani SK, Tanaka T, Geller F, Luan J, Hui J, Mägi R, Dimitriou M, Garcia ME, Ho WK, Wright MJ, Rose LM, Magnusson PKE, Pedersen NL, Couper D, Oostra BA, Hofman A, Ikram MA, Tiemeier HW, Uitterlinden AG, van Rooij FJA, Barroso I, Johansson I, Xue L, Kaakinen M, Milani L, Power C, Snieder H, Stolk RP, Baumeister SE, Biffar R, Gu F, Bastardot F, Kutalik Z, Jacobs DR Jr, Forouhi NG, Mihailov E, Lind L, Lindgren C, Michaëlsson K, Morris A, Jensen M, Khaw KT, Luben RN, Wang JJ, Männistö S, Perälä MM, Kähönen M, Lehtimäki T, Viikari J, Mozaffarian D, Mukamal K, Psaty BM, Döring A, Heath AC, Montgomery GW, Dahmen N, Carithers T, Tucker KL, Ferrucci L, Boyd HA, Melbye M, Treur JL, Mellström D, Hottenga JJ, Prokopenko I, Tönjes A, Deloukas P, Kanoni S, Lorentzon M, Houston DK, Liu Y, Danesh J, Rasheed A, Mason MA, Zonderman AB, Franke L, Kristal BS, Karjalainen J, Reed DR, Westra HJ, Evans MK, Saleheen D, Harris TB, Dedoussis G, Curhan G, Stumvoll M, Beilby J, Pasquale LR, Feenstra B, Bandinelli S, Ordovas JM, Chan AT, Peters U, Ohlsson C, Gieger C, Martin NG, Waldenberger M, Siscovick DS, Raitakari O, Eriksson JG, Mitchell P, Hunter DJ, Kraft P, Rimm EB, Boomsma DI, Borecki IB, Loos RJF, Wareham NJ, Vollenweider P, Caporaso N, Grabe HJ, Neuhouser ML, Wolffenbuttel BHR, Hu FB, Hyppönen E, Järvelin MR, Cupples LA, Franks PW, Ridker PM, van Duijn CM, Heiss G, Metspalu A, North KE, Ingelsson E, Nettleton JA, van Dam RM, Chasman DI [Contributors: Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras M, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Dong J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Hershey MS, Wurster I, Mätzler W, Hudson G, Hunt SE, Huttenlocher J, Illig T, München HZ, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, O' Sullivan SS, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Sidransky E, Smith C, Spencer CCA, Stefánsson H, Bettella F, Stockton JD, Strange A, Talbot K, Tanner M, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Sabatier P, Wood NW, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Singleton A, Cookson M, Hernandez D, Nalls M, Zonderman A, Ferrucci L, Johnson R, Longo D, O'Brien R, Traynor B, Troncoso J, van der Brug M, Zielke R, Weale M, Ramasamy A, Box PO]] , Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. MOL PSYCHIATR 2015;20 (5):647-656 [PubMed]
de Bie RMA, editor, Syllabus Biemond Cursus Bewegingsstoornissen. S.l.: s.n.; 2015. -p. ISBN 978-90-76756-31-8
de Bie RMA. Wanneer operatieve therapie overwegen bij de ziekte van Parkinson in: de Bie RMA, editor. Syllabus Biemond Cursus Bewegingsstoornissen. S.l.: s.n.; 2015., p. -
den Brok MGHE, van Dalen JW, van Gool WA, Moll van Charante EP, de Bie RMA, Richard E, Apathy in Parkinson's disease: A systematic review and meta-analysis. MOVEMENT DISORD 2015;30 (6):759-769 [PubMed]
Engelen M, Barbier M, Dijkstra IME, Schür R, de Bie RM, Verhamme C, Dijkgraaf MGW, Aubourg PA, Wanders RJA, van Geel BM, de Visser M, Poll-The BT, Kemp S, Reply: Age-dependent penetrance among females with X-linked adrenoleukodystrophy. BRAIN 2015;138 (2):e326 [PubMed]
Nalls MA, Bras J, Hernandez DG, Keller MF, Majounie E, Renton AE, Saad M, Jansen I, Guerreiro R, Lubbe S, Plagnol V, Gibbs JR, Schulte C, Pankratz N, Sutherland M, Bertram L, Lill CM, DeStefano AL, Faroud T, Eriksson N, Tung JY, Edsall C, Nichols N, Brooks J, Arepalli S, Pliner H, Letson C, Heutink P, Martinez M, Gasser T, Traynor BJ, Wood N, Hardy J, Singleton AB [Contributors: Nalls MA, Plagnol V, Hernandez DG, Edsall C, Nichols N, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Dong J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Wurster I, Mätzler W, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, Lubbe S, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, O'Sullivan SS, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CCA, Stefánsson H, Bettella F, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Wood NW, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Renton AE, Pilner H, Letson C, Factor S, Higgins D, Evans S, Shill H, Stacy M, Danielson J, Marlor L, Williamson K, Jankovic J, Hunter C, Simon D, Ryan P, Scollins L, Saunders-Pullman R, Boyar K, Costan-Toth C, Ohmann E, Sudarsky L, Joubert C, Friedman J, Chou K, Fernandez H, Lannon M, Galvez-Jimenez N, Podichetty A, Thompson K, Lewitt P, Deangelis M, O'Brien C, Seeberger L, Dingmann C, Judd D, Marder K, Fraser J, Harris J, Bertoni J, Peterson C, Rezak M, Medalle G, Chouinard S, Panisset M, Hall J, Poiffaut H, Calabrese V, Roberge P, Wojcieszek J, Belden J, Jennings D, Marek K, Mendick S, Reich S, Dunlop B, Jog M, Horn C, Uitti R, Turk M, Ajax T, Mannetter J, Sethi K, Carpenter J, Dill B, Hatch L, Ligon K, Narayan S, Blindauer K, Abou-Samra K, Petit J, Elmer L, Aiken E, Davis K, Schell C, Wilson S, Velickovic M, Koller W, Phipps S, Feigin A, Gordon M, Hamann J, Licari E, Marotta-Kollarus M, Shannon B, Winnick R, Simuni T, Videnovic A, Kaczmarek A, Williams K, Wolff M, Rao J, Cook M, Fernandez M, Kostyk S, Hubble J, Campbell A, Reider C, Seward A, Camicioli R, Carter J, Nutt J, Andrews P, Morehouse S, Stone C, Mendis T, Grimes D, Alcorn-Costa C, Gray P, Haas K, Vendette J, Sutton J, Hutchinson B, Young J, Rajput A, Klassen L, Shirley T, Manyam B, Simpson P, Whetteckey J, Wulbrecht B, Truong D, Pathak M, Frei K, Luong N, Tra T, Tran A, Vo J, Lang A, Kleiner-Fisman G, Nieves A, Johnston L, So J, Podskalny G, Giffin L, Atchison P, Allen C, Martin W, Wieler M, Suchowersky O, Furtado S, Klimek M, Hermanowicz N, Niswonger S, Shults C, Fontaine D, Aminoff M, Christine C, Diminno M, Hevezi J, Dalvi A, Kang U, Richman J, Uy S, Sahay A, Gartner M, Schwieterman D, Hall D, Leehey M, Culver S, Derian T, Demarcaida T, Thurlow S, Rodnitzky R, Dobson J, Lyons K, Pahwa R, Gales T, Thomas S, Shulman L, Weiner W, Dustin K, Singer C, Zelaya L, Tuite P, Hagen V, Rolandelli S, Schacherer R, Kosowicz J, Gordon P, Werner J, Serrano C, Roque S, Kurlan R, Berry D, Gardiner I, Hauser R, Sanchez-Ramos J, Zesiewicz T, Delgado H, Price K, Rodriguez P, Wolfrath S, Pfeiffer R, Davis L, Pfeiffer B, Dewey R, Hayward B, Johnson A, Meacham M, Estes B, Walker F, Hunt V, O'Neill C, Racette B, Swisher L, Eriksson N, Dijamco C, Drabant EM, Dorfman E, Tung JY, Hinds DA, Mountain JL, Wojcicki A, Lill C, Bertram L, Lew M, Klein C, Golbe L, Mark MH, Growdon J, Huggins N, Wooten GF, Watts R, Guttman M, Perlmutter J, Goldwurm S, Pezzoli G, Saint-Hilaire MH, Massood T, Baker K, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn D, Chinnery P, Pramstaller P, Al-hinti J, Moller A, Ostergaard K, Sherman S, Roxburgh R, Snow B, Slevin J, Cambi F, Kay D, Montimurro J, Kusel V, Samii A, Martinez E, Yearout D, Agarwal P, Griffith A, Roberts JW, Higgins DS, Molho E, Rosen A, Clark LN, Liu X, Lee JH, Cheng R, Louis ED, Cote LJ, Waters C, Ford B, Fahn S, Vance JM, Beecham GW, Martin ER, Nuytemans K, Pericak-Vance MA, Haines JL, DeStefano A, Seshadri S, Choi SH, Frank S, Bis JC, Psaty BM, Rice K, Longstreth WT Jr, Ton TGN, Jain S, Ikram MA, van Duijn CM, Uitterlinden A, Verlinden V, Koudstaal PJ, Kara E, Xiromerisiou G, Dardiotis E, Tsimourtou V, Spanaki C, Plaitakis A, Bozi M, Stefanis L, Vassilatis D, Koutsis G, Panas M, Houlden H, Hadjigeorgiou GM, Bras J, Lunnon K, Lupton M, Powell J, Parkkinen L, Ansorge O]] , NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases. NEUROBIOL AGING 2015;36 (3):1605.e7-1605.12 [PubMed]
Odekerken VJ, Boel JA, Schmand BA, de Bie RM, NEUROPSYCHOLOGICAL OUTCOME AFTER DEEP BRAIN STIMULATION FOR PARKINSON DISEASE Response. NEUROLOGY 2015;85 (16):1433-1434 [PubMed]
Odekerken VJJ, Boel JA, Geurtsen GJ, Schmand BA, Dekker IP, de Haan RJ, Schuurman PR, de Bie RMA [Contributors: Odekerken VJJ, Boel JA, van Laar T, Staal MJ, Mosch A, Hoffmann CFE, Nijssen PCG, Beute GN, van Vugt JPP, Mathieu WPM, Contarino MF, Mink MSJ, Bour LJ, van den Munckhof P, Geurtsen GJ, Schmand BA, de Haan RJ, Schuurman PR, de Bie RMA]] , Neuropsychological outcome after deep brain stimulation for Parkinson disease. NEUROLOGY 2015;84 (13):1355-1361 [PubMed]
Suwijn SR, van Boheemen CJM, de Haan RJ, Tissingh G, Booij J, de Bie RMA, The diagnostic accuracy of dopamine transporter SPECT imaging to detect nigrostriatal cell loss in patients with Parkinson's disease or clinically uncertain parkinsonism: a systematic review. EJNMMI RES 2015;5:12 [PubMed]
Verhagen R, Zwartjes DGM, Heida T, Wiegers EC, Contarino MF, de Bie RMA, van den Munckhof P, Schuurman PR, Veltink PH, Bour LJ, Advanced target identification in STN-DBS with beta power of combined local field potentials and spiking activity. J NEUROSCI METH 2015;253:116-125 [PubMed]
Verschuur CVM, Suwijn SR , Post B, Dijkgraaf M, Bloem BR, van Hilten JJ, van Laar T, Tissingh G, Deuschl G, Lang AE, de Haan RJ, de Bie RMA, Protocol of a randomised delayed-start double-blind placebo-controlled multi-centre trial for Levodopa in EArly Parkinson's disease: the LEAP-study. BMC NEUROL 2015;15 (1):236 [PubMed]
Beilina A, Rudenko IN, Kaganovich A, Civiero L, Chau H, Kalia SK, Kalia LV, Lobbestael E, Chia R, Ndukwe K, Ding J, Nalls MA, Olszewski M, Hauser DN, Kumaran R, Lozano AM, Baekelandt V, Greene LE, Taymans JM, Greggio E, Cookson MR [Contributors: Nalls MA, Plagnol V, Martinez M, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson O, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, München HZ, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CCA, Stefánsson H, Steinberg S, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW, Chinnery PF, Ferrucci L, Johnson R, Longo DL, Majounie E, Nalls MA, O'Brien R, Troncoso J, van der Brug M, Zielke HR, Zonderman AB]] , Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. P NATL ACAD SCI USA 2014;111 (7):2626-2631 [PubMed]
Buijink AWG, Caan MWA, Contarino MF, Schuurman PR, van den Munckhof P, de Bie RMA, Olabarriaga SD, Speelman JD, van Rootselaar AF, Structural changes in cerebellar outflow tracts after thalamotomy in essential tremor. PARKINSONISM RELAT D 2014;20 (5):554-557 [PubMed]
Contarino MF, Bour LJ, Verhagen R, Lourens MAJ, de Bie RMA, van den Munckhof P, Schuurman PR, Directional steering: A novel approach to deep brain stimulation. NEUROLOGY 2014;83 (13):1163-1169 [PubMed]
Contarino MF, van den Munckhof P, Tijssen MAJ, de Bie RMA, Bosch DA, Schuurman PR, Speelman JD, Selective peripheral denervation: comparison with pallidal stimulation and literature review. J NEUROL 2014;261 (2):300-308 [PubMed]
Dong J, Gao J, Nalls M, Gao X, Huang X, Han J, Singleton AB, Chen H [Contributors: Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Dong J, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson Ó, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CCA, Stefánsson H, Steinberg S, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Wood NW, Hardy J, Heutink P, Brice A, Gasser T, B A]] , Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease. NEUROBIOL AGING 2014;35 (6):1512.e5-1512.10 [PubMed]
Engelen M, Barbier M, Dijkstra IME, Schür R, de Bie RMA, Verhamme C, Dijkgraaf MGW, Aubourg PA, Wanders RJA, van Geel BM, de Visser M, Poll-The BT, Kemp S, X-linked adrenoleukodystrophy in women: a cross-sectional cohort study. BRAIN 2014;137 (Part 3):693-706 [PubMed]
Geurtsen GJ, Hoogland J, Goldman JG, Schmand BA, Tröster AI, Burn DJ, Litvan I [Contributors: Filoteo JV, Litvan I, Goldman JG, Hurtig H, Chen-Plotkin A, Adler CH, Jacobson SA, Leverenz J, Zabetian C, Huang X, Eslinger PJ, Marras C, Duff-Canning S, Dalrymple-Alford JC, Anderson TJ, Naismith SL, Lewis SJG, Wu RM, Yu RL, Bhattacharyya KB, Williams-Gray CH, Breen DP, Barker RA, Yarnall AJ, de Bie RMA, Koene T, Klein M, Trautmann E, Mollenhauer B, Dodel R, Kulisevsky J, Pagonabaragga J, Rodriguez-Oroz MC, Gasca-Salas C, Junque C, Segura B, Sportiello MT, Cammisuli DM, Barone P, Pedersen KF, Alves G]] , Parkinson's disease mild cognitive impairment: application and validation of the criteria. J PARKINSON DIS 2014;4 (2):131-137 [PubMed]
Lammers NM, Sondermeijer BM, Twickler TBM, de Bie RM, Ackermans MT, Fliers E, Schuurman PR, la Fleur SE, Serlie MJ, Subthalamic nucleus stimulation does not influence basal glucose metabolism or insulin sensitivity in patients with Parkinson's disease. FRONT NEUROSCI-SWITZ 2014;8:95 [PubMed]
Nalls MA, Pankratz N, Lill CM, Do CB, Hernandez DG, Saad M, DeStefano AL, Kara E, Bras J, Sharma M, Schulte C, Keller MF, Arepalli S, Letson C, Edsall C, Stefansson H, Liu X, Pliner H, Lee JH, Cheng R, Ikram MA, Ioannidis JPA, Hadjigeorgiou GM, Bis JC, Martinez M, Perlmutter JS, Goate A, Marder K, Fiske B, Sutherland M, Xiromerisiou G, Myers RH, Clark LN, Stefansson K, Hardy JA, Heutink P, Chen H, Wood NW, Houlden H, Payami H, Brice A, Scott WK, Gasser T, Bertram L, Eriksson N, Foroud T, Singleton AB [Contributors: Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Dong J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Wurster I, Mätzler W, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CCA, Stefánsson H, Bettella F, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Wood NW, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Factor S, Higgins D, Evans S, Shill H, Stacy M, Danielson J, Marlor L, Williamson K, Jankovic J, Hunter C, Simon D, Ryan P, Scollins L, Saunders-Pullman R, Boyar K, Costan-Toth C, Ohmann E, Sudarsky L, Joubert C, Friedman J, Chou K, Fernandez H, Lannon M, Galvez-Jimenez N, Podichetty A, Thompson K, Lewitt P, Deangelis M, O'Brien C, Seeberger L, Dingmann C, Judd D, Marder K, Fraser J, Harris J, Bertoni J, Peterson C, Rezak M, Medalle G, Chouinard S, Panisset M, Hall J, Poiffaut H, Calabrese V, Roberge P, Wojcieszek J, Belden J, Jennings D, Marek K, Mendick S, Reich S, Dunlop B, Jog M, Horn C, Uitti R, Turk M, Ajax T, Mannetter J, Sethi K, Carpenter J, Dill B, Hatch L, Ligon K, Narayan S, Blindauer K, Abou-Samra K, Petit J, Elmer L, Aiken E, Davis K, Schell C, Wilson S, Velickovic M, Koller W, Phipps S, Feigin A, Gordon M, Hamann J, Licari E, Marotta-Kollarus M, Shannon B, Winnick R, Simuni T, Videnovic A, Kaczmarek A, Williams K, Wolff M, Rao J, Cook M, Fernandez M, Kostyk S, Hubble J, Campbell A, Reider C, Seward A, Camicioli R, Carter J, Nutt J, Andrews P, Morehouse S, Stone C, Mendis T, Grimes D, Alcorn-Costa C, Gray P, Haas K, Vendette J, Sutton J, Hutchinson B, Young J, Rajput A, Klassen L, Shirley T, Manyam B, Simpson P, Whetteckey J, Wulbrecht B, Truong D, Pathak M, Frei K, Luong N, Tra T, Tran A, Vo J, Lang A, Kleiner- Fisman G, Nieves A, Johnston L, So J, Podskalny G, Giffin L, Atchison P, Allen C, Martin W, Wieler M, Suchowersky O, Furtado S, Klimek M, Hermanowicz N, Niswonger S, Shults C, Fontaine D, Aminoff M, Christine C, Diminno M, Hevezi J, Dalvi A, Kang U, Richman J, Uy S, Sahay A, Gartner M, Schwieterman D, Hall D, Leehey M, Culver S, Derian T, Demarcaida T, Thurlow S, Rodnitzky R, Dobson J, Lyons K, Pahwa R, Gales T, Thomas S, Shulman L, Weiner W, Dustin K, Singer C, Zelaya L, Tuite P, Hagen V, Rolandelli S, Schacherer R, Kosowicz J, Gordon P, Werner J, Serrano C, Roque S, Kurlan R, Berry D, Gardiner I, Hauser R, Sanchez-Ramos J, Zesiewicz T, Delgado H, Price K, Rodriguez P, Wolfrath S, Pfeiffer R, Davis L, Pfeiffer B, Dewey R, Hayward B, Johnson A, Meacham M, Estes B, Walker F, Hunt V, O'Neill C, Racette B, Swisher L, Dijamco C, Conley ED, Dorfman E, Tung JY, Hinds DA, Mountain JL, Wojcicki A, Lew M, Klein C, Golbe L, Growdon J, Wooten GF, Watts R, Guttman M, Goldwurm S, Saint-Hilaire MH, Baker K, Litvan I, Nicholson G, Nance M, Drasby E, Isaacson S, Burn D, Pramstaller P, Al-hinti J, Moller A, Sherman S, Roxburgh R, Slevin J, Perlmutter J, Mark MH, Huggins N, Pezzoli G, Massood T, Itin I, Corbett A, Chinnery P, Ostergaard K, Snow B, Cambi F, Kay D, Samii A, Agarwal P, Roberts JW, Higgins DS, Molho E, Rosen A, Montimurro J, Martinez E, Griffith A, Kusel V, Yearout D, Zabetian C, Clark LN, Liu X, Lee JH, Taub RC, Louis ED, Cote LJ, Waters C, Ford B, Fahn S, Vance JM, Beecham GW, Martin ER, Nuytemans K, Pericak-Vance MA, Haines JL, DeStefano A, Seshadri S, Choi SH, Frank S, Bis JC, Psaty BM, Rice K, Longstreth WT Jr, Ton TGN, Jain S, Ikram MA, van Duijn CM, Verlinden VJ, Koudstaal PJ, Singleton A, Cookson M, Hernandez D, Nalls M, Zonderman A, Ferrucci L, Johnson R, Longo D, O'Brien R, Traynor B, Troncoso J, van der Brug M, Zielke R, Weale M, Ramasamy A, Kara E, Xiromerisiou G, Dardiotis E, Tsimourtou V, Spanaki C, Plaitakis A, Bozi M, Stefanis L, Vassilatis D, Koutsis G, Panas M, Houlden H, Hadjigeorgiou GM, Lunnon K, Lupton M, Powell J, Parkkinen L, Ansorge O]] , Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. 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Nalls MA, Saad M, Noyce AJ, Keller MF, Schrag A, Bestwick JP, Traynor BJ, Gibbs JR, Hernandez DG, Cookson MR, Morris HR, Williams N, Gasser T, Heutink P, Wood N, Hardy J, Martinez M, Singleton AB [Contributors: Nalls M, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson Ó, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CCA, Stefánsson H, Steinberg S, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW, Donnelly P, Barroso I, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Jankowski J, Markus HS, Mathew CG, Palmer NA, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Band G, Bellenguez C, Freeman C, Hellenthal G, Giannoulatou E, Pirinen M, Pearson R, Su Z, Vukcevic D, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Hammond N, Jayakumar A, McCann OT, Liddle J, Potter SC, Ravindrarajah R, Ricketts M, Waller M, Weston P, Widaa S, Whittaker P, McCarthy MI, Nalls MA, Zonderman AB, Ferrucci L, Johnson R, Longo DL, O'Brien R, Traynor B, Troncoso J, van der Brug M, Zielke RH, Weale ME, Ramasamy A, Walker R]] , Genetic comorbidities in Parkinson's disease. HUM MOL GENET 2014;23 (3):831-841 [PubMed]
Pisters MF, Veenhof C, van Dijk GM, Dekker J [Contributors: Beelen A, de Bie RMA, Dekker J, Lankhorst GJ, Nollet F, Pisters MF, Tersteeg IM, Veenhof C, Velseboer DC]] , Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role of reduced muscle strength. OSTEOARTHR CARTILAGE 2014;22 (2):171-177 [PubMed]
Suwijn SR , Berendse HW, Verschuur CVM, de Bie RMA, Booij J, Serotonin transporter availability in early stage Parkinson's disease and multiple system atrophy. ISRN NEUROL 2014;2014:345132 [PubMed]
Suwijn SR, de Bruin K, de Bie RMA, Booij J, The role of SPECT imaging of the dopaminergic system in translational research on Parkinson's disease. PARKINSONISM RELAT D 2014;20 (Suppl. 1):S184-S186 [PubMed]
Broeders M, de Bie RMA, Velseboer DC , Speelman JD, Muslimovic D, Schmand B, Evolution of mild cognitive impairment in Parkinson disease. NEUROLOGY 2013;81 (4):346-352 [PubMed]
Broeders M, Velseboer DC, de Bie R, Speelman JD, Muslimovic D, Post B, de Haan R, Schmand B, Cognitive Change in Newly-Diagnosed Patients with Parkinson's Disease: A 5-Year Follow-up Study. J INT NEUROPSYCH SOC 2013;19 (6):695-708 [PubMed]
Contarino MF. Improving surgical treatment for movement disorders. s.l.: s.n.; 2013. 178p. ISBN 9789461084057 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Schaik IN, de Koning-Tijssen MAJ; copromotor(s): de Bie RMA, van Rootselaar AF, Schuurman PR)
Contarino MF, Bot M, Speelman JD, de Bie RMA, Tijssen MA, Denys D, Bour LJ, Schuurman PR, van den Munckhof P, Postoperative displacement of deep brain stimulation electrodes related to lead-anchoring technique. NEUROSURGERY 2013;73 (4):681-8; discussion 188 [PubMed]
Holmans P, Moskvina V, Jones L, Sharma M, Vedernikov A, Buchel F, Saad M, Sadd M, Bras JM, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P, Wood NW, Martinez M, Singleton AB, Nalls MA, Hardy J, Morris HR, Williams NM [Contributors: Arepalli S, Barker R, Barrett J, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Brice A, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Durr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gasser T, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson O, Hardy J, Harris C, Hernandez DG, Heutink P, van Hilten JJ, Hofman A, Hollenbeck A, Holmans P, Holton J, Hu M, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Langford C, Lees A, Lesage S, Lichtner P, Limousin P, Lopez G, Lorenz D, Martinez M, McNeill A, Moorby C, Moore M, Morris H, Morrison KE, Moskvina V, Mudanohwo E, Nalls MA, Pearson J, Perlmutter JS, Pétursson H, Plagnol V, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Saad M, Sawcer S, Schapira A, Scheffer H, Sharma M, Shaw K, Sheerin UM, Shoulson I, Schulte C, Sidransky E, Simón-Sánchez J, Singleton AB, Smith C, Stefánsson H, Stefánsson K, Steinberg S, Stockton JD, Sveinbjornsdottir S, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Wood N]] , A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. HUM MOL GENET 2013;22 (5):1039-1049 [PubMed]
Klebe S, Golmard JL, Nalls MA, Saad M, Singleton AB, Bras JM, Hardy J, Simon-Sanchez J, Heutink P, Kuhlenbäumer G, Charfi R, Klein C, Hagenah J, Gasser T, Wurster I, Lesage S, Lorenz D, Deuschl G, Durif F, Pollak P, Damier P, Tison F, Durr A, Amouyel P, Lambert JC, Tzourio C, Maubaret C, Charbonnier-Beaupel F, Tahiri K, Vidailhet M, Martinez M, Brice A, Corvol JC [Contributors: Agid Y, Anheim M, Bonnet AM, Borg M, Brice A, Broussolle E, Corvol JC, Damier P, Destée A, Durr A, Durif F, Klebe S, Lohmann E, Martinez M, Penet C, Pollak P, Krack P, Rascol O, Tison F, Tranchant C, Vérin M, Viallet F, Plagnol V, Bras JM, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Amouyel P, Arepalli S, Band G, Barker RA, Bellinguez C, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RM, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Dexter DT, van Dijk KD, Dillman A, Durif F, Edkins S, Evans JR, Foltynie T, Freeman C, Gao J, Gardner M, Gibbs R, Goate A, Gray E, Guerreiro R, Gústafsson O, Harris C, Hellenthal G, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Morris H, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Pearson R, Perlmutter JS, Pétursson H, Pirinen M, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, de Silva R, Smith C, Spencer CC, Stefánsson H, Steinberg S, Stockton JD, Strange A, Su Z, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden G, Vandrovcova J, Velseboer D, Vidailhet M, Vukcevic D, Walker R, van de Warrenburg B, Weale ME, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Martinez M, Donnelly P, Hardy J, Heutink P, Brice A, Gasser T, Wood NW, Singleton AB]] , The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism. J NEUROL NEUROSUR PS 2013;84 (6):666-673 [PubMed]
Laurent V, van den Munckhof P, Contarino MF, van der Veer O , Velseboer DC, Scholten MN, Schuurman PR, de Bie RMA, Patient perception of deep brain stimulation hardware. MOVEMENT DISORD 2013;28 (12):1754-1755 [PubMed]
Moskvina V, Harold D, Russo G, Vedernikov A, Sharma M, Saad M, Holmans P, Bras JM, Bettella F, Keller MF, Nicolaou N, Simón-Sánchez J, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P, Wood N, Martinez M, Singleton AB, Nalls MA, Hardy J, Owen MJ, O'Donovan MC, Williams J, Morris HR, Williams NM [Contributors: Dillman A, Hernandez DG, Brooks J, Chong S, Cookson MR, Gibbs JR, Moore M, Keller MF, Nalls MA, Singleton AB, Traynor BJ, Arepalli S, Charlesworth G, Plagnol V, Ryten M, Trabzuni D, Guerreiro R, Bras JM, Hardy J, Schulte C, Berg D, Brockmann K, Gasser T, Huber H, Sharma M, Sheerin UM, Bhatia K, Martinez M, Saad M, Simón-Sánchez J, Bochdanovits Z, Heutink P, Rizzu P, Lesage S, Vidailhet M, Brice A, Corvol JC, Curie PeM, Barker R, Hunt SE, Gray E, Edkins S, Tashakkori-Ghanbaria A, Barrett J, Deloukasm P, Potter S, Ben-Shlomo Y, van Dijk KD, Berendse HW, Velseboer D, de Bie RMA, Biffi A, Bloem B, van deWarrenburg B, Post B, Riess O, Bonin M, Burn DJ]] , Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk. JAMA NEUROL 2013;70 (10):1268-1276 [PubMed]
Odekerken VJJ, de Haan RJ, Schurrman PR, de Bie RMA, Authors' reply. Subthalamic versus globus pallidus deep brain stimulation. LANCET NEUROL 2013;12 (4):329 [PubMed]
Odekerken VJJ, van Laar T, Staal MJ, Mosch A, Hoffmann CFE, Nijssen PCG, Beute GN, van Vugt JPP, Lenders MWPM, Contarino MF, Mink MSJ, Bour LJ, van den Munckhof P, Schmand BA, de Haan RJ, Schuurman PR, de Bie RMA, Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial. LANCET NEUROL 2013;12 (1):37-44 [PubMed]
Pichler I, del Greco M F, Gögele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH, Nalls M, Keller MF, Benyamin B, Whitfield JB, Pramstaller PP, Hicks AA, Thompson JR, Minelli C [Contributors: Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Illig T, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Perlmutter JS, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CCA, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Martinez M, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW, Donnelly P, Barroso I, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Jankowski J, Markus HS, Mathew CG, Palmer CNA, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Band G, Bellenguez C, Freeman C, Hellenthal G, Giannoulatou E, Pirinen M, Pearson R, Su Z, Vukcevic D, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Hammond N, Jayakumar A, McCann OT, Liddle J, Potter SC, Ravindrarajah R, Ricketts M, Waller M, Weston P, Widaa S, Whittaker P, McCarthy MI, Ouwehand WH, Radhakrishnan A, Sambrook J, Toniolo D, Traglia M, Camaschella C, Metspalu A, Esko T, Gieger C, Ried J, Meitinger T, Oexle K, Winkelmann J, Swinkels D, Vermeulen S, van Duijn C, Broer L, Beilby J, Hui J, Anderson D, Visscher P, Martin N]] , Serum iron levels and the risk of Parkinson disease: a mendelian randomization study. PLOS MED 2013;10 (6):e1001462 [PubMed]
Suwijn SR, Berendse HW, Verschuur CVM, Winogrodzka A, de Bie RMA, Booij J, SERT-to-DAT ratios in early Parkinson's disease do not correlate with the development of dyskinesias. EJNMMI RES 2013;3 (1):UNSP 44 [PubMed]
Velseboer DC, Broeders M, Post B, van Geloven N, Speelman JD, Schmand B, de Haan RJ, de Bie RMA, Prognostic factors of motor impairment, disability, and quality of life in newly diagnosed PD. NEUROLOGY 2013;80 (7):627-633 [PubMed]
Volkmann J, Albanese A, Antonini A, Chaudhuri KR, Clarke CE, de Bie RMA, Deuschl G, Eggert K, Houeto JL, Kulisevsky J, Nyholm D, Odin P, Ostergaard K, Poewe W, Pollak P, Rabey JM, Rascol O, Ruzicka E, Samuel M, Speelman H, Sydow O, Valldeoriola F, van der Linden C, Oertel W, Selecting deep brain stimulation or infusion therapies in advanced Parkinson's disease: an evidence-based review. J NEUROL 2013;260 (11):2701-2714 [PubMed]
Contarino MF, Bour LJ, Bot M, van den Munckhof P, Speelman JD, Schuurman PR , de Bie RM, Tremor-specific neuronal oscillation pattern in dorsal subthalamic nucleus of parkinsonian patients. BRAIN STIMUL 2012;5 (3):305-314 [PubMed]
Keller MF, Saad M, Bras J, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Büchel F, Sharma M, Gibbs JR, Schulte C, Moskvina V, Durr A, Holmans P, Kilarski LL, Guerreiro R, Hernandez DG, Brice A, Ylikotila P, Stefánsson H, Majamaa K, Morris HR, Williams N, Gasser T, Heutink P, Wood NW, Hardy J, Martinez M, Singleton AB, Nalls MA [Contributors: Keller MF, Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras J, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Segalen V, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Montpied G, Dürr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson O, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CCA, Stefánsson H, Steinberg S, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Sabatier P, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW, Donnelly P, Barroso I, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Jankowski J, Markus HS, Mathew CG, Palmer CNA, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Band G, Bellenguez C, Freeman C, Hellenthal G, Giannoulatou E, Pirinen M, Pearson R, Su Z, Vukcevic D, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Hammond N, Jayakumar A, McCann OT, Liddle J, Potter SC, Ravindrarajah R, Ricketts M, Waller M, Weston P, Widaa S, Whittaker P]] , Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. HUM MOL GENET 2012;21 (22):4996-5009 [PubMed]
Mittag F, Büchel F, Saad M, Jahn A, Schulte C, Bochdanovits Z, Simón-Sánchez J, Nalls MA, Keller M, Hernandez DG, Gibbs JR, Lesage S, Brice A, Heutink P, Martinez M, Wood NW, Hardy J, Singleton AB, Zell A, Gasser T, Sharma M [Contributors: Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson Ó, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Hershey MS, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, München HZ, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, O'Sullivan SS, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Sidransky E, Smith C, Spencer CCA, Stefánsson H, Steinberg S, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW]] , Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities. HUM MUTAT 2012;33 (12):1708-1718 [PubMed]
Contarino MF, Bour LJ, Bot M, van den Munckhof P, Speelman JD, Schuurman PR, de Bie RMA, Pallidotomy suppresses beta power in the subthalamic nucleus of Parkinson's disease patients. EUR J NEUROSCI 2011;33 (7):1275-1280 [PubMed]
Contarino MF, Speelman JD, de Bie RMA, Schuurman PR, van den Munckhof P, Bilateral Cerebellorubrothalamic Fibers Stimulation for Essential Tremor?. MOVEMENT DISORD 2011;26 (7):1366-1367 [PubMed]
Marras C, Schüle B, Schuele B, Munhoz RP, Rogaeva E, Langston JW, Kasten M, Meaney C, Klein C, Wadia PM, Lim SY, Chuang RSI, Zadikof C, Steeves T, Prakash KM, de Bie RMA, Adeli G, Thomsen T, Johansen KK, Teive HA, Asante A, Reginold W, Lang AE, Phenotype in parkinsonian and nonparkinsonian LRRK2 G2019S mutation carriers. NEUROLOGY 2011;77 (4):325-333 [PubMed]
Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simon-Sanchez J, Schulte C, Lesage S, Sveinbjornsdottir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Duerr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gustafsson O, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jonsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Perlmutter JS, Petursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CCA, Stefansson H, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefansson K, Martinez M, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW, Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. LANCET 2011;377 (9766):641-649
Plagnol V, Nalls MA, Bras JM, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simon-Sanchez J, Schulte C, Lesage S, Sveinbjornsdottir S, Amouyel P, Arepalli S, Band G, Barker RA, Bellinguez C, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RMA, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Duerr A, Edkins S, Evans JR, Foltynie T, Freeman C, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gustafsson O, Harris C, Hellenthal G, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jonsson PV, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris H, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Pearson R, Perlmutter JS, Petursson H, Pirinen M, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, de Silva R, Smith C, Spencer CCA, Stefansson H, Steinberg S, Stockton JD, Strange A, Su Z, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Vandrovcova J, Velseboer D, Vidailhet M, Vukcevic D, Walker R, van de Warrenburg B, Weale ME, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefansson K, Martinez M, Donnelly P, Singleton AB, Hardy J, Heutink P, Brice A, Gasser T, Wood NW, A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease. PLOS GENET 2011;7 (6):e1002142
Simón-Sánchez J, van Hilten JJ, van de Warrenburg B, Post B, Berendse HW, Arepalli S, Hernandez DG, de Bie RMA, Velseboer D, Scheffer H, Bloem B, van Dijk KD, Rivadeneira F, Hofman A, Uitterlinden AG, Rizzu P, Bochdanovits Z, Singleton AB, Heutink P, Genome-wide association study confirms extant PD risk loci among the Dutch. EUR J HUM GENET 2011;19 (6):655-661 [PubMed]
Velseboer DC, de Haan RJ, Wieling W, Goldstein DS, de Bie RMA, Prevalence of orthostatic hypotension in Parkinson's disease: a systematic review and meta-analysis. PARKINSONISM RELAT D 2011;17 (10):724-729 [PubMed]
Bour LJ, Contarino MF, Foncke EMJ, de Bie RMA, van den Munckhof P, Speelman JD, Schuurman PR, Long-term experience with intraoperative microrecording during DBS neurosurgery in STN and GPi. ACTA NEUROCHIR 2010;152 (12):2069-2077 [PubMed]
Groen JL, de Bie RMA, Foncke EMJ, Roos RAC, Leenders KL, Tijssen MAJ, Late-onset Huntington disease with intermediate CAG repeats: true or false?. J NEUROL NEUROSUR PS 2010;81 (2):228-230 [PubMed]
Groen JL, Ritz K, Contarino MF, van de Warrenburg BP, Aramideh M, Foncke EM, van Hilten JJ, Schuurman PR, Speelman JD, Koelman JH, de Bie RMA, Baas F, Tijssen MA, DYT6 Dystonia: Mutation Screening, Phenotype, and Response to Deep Brain Stimulation. MOVEMENT DISORD 2010;25 (14):2420-2427 [PubMed]
Hoogland J, de Bie RMA, Williams-Gray CH, Muslimović D, Schmand B, Post B, Catechol-O-methyltransferase Val158Met and Cognitive Function in Parkinson's Disease. MOVEMENT DISORD 2010;25 (15):2550-2554 [PubMed]
Speelman JD, Contarino MF, Schuurman PR, Tijssen MAJ, de Bie RMA, Deep brain stimulation for dystonia: patient selection and outcomes. EUR J NEUROL 2010;17 (Suppl. 1):102-106 [PubMed]
Surie S, Tijssen MAJ, Biervliet JD, de Beaumont EM, Kloek JJ, Rutten PMMJ, Smeding HMM, Bresser P, de Bie RMA, Chorea in adults following pulmonary endarterectomy. MOVEMENT DISORD 2010;25 (8):1101-1104 [PubMed]
van den Munckhof P, Contarino MF, Bour LJ, Speelman JD, de Bie RMA, Schuurman PR, Postoperative curving and upward displacement of deep brain stimulation electrodes caused by brain shift. NEUROSURGERY 2010;67 (1):49-53; discussion 53-4 [PubMed]
Esselink RAJ, de Bie RMA, de Haan RJ, Lenders MWPM, Nijssen PCG, van Laar T, Schuurman PR, Bosch DA, Speelman JD, Long-term superiority of subthalamic nucleus stimulation over pallidotomy in Parkinson disease. NEUROLOGY 2009;73 (2):151-153 [PubMed]
Odekerken VJJ, Post B, Verschuur CVM, de Bie RMA, Vroege behandeling met levodopa bij de ziekte van Parkinson. NED TIJDSCHR GENEESKD 2009;153:A286 [PubMed]
van Thiel PPAM, de Bie RMA, Eftimov F, Tepaske R, Zaaijer HL, van Doornum GJJ, Schutten M, Osterhaus ADME, Majoie CBLM, Aronica E, Fehlner-Gardiner C, Wandeler AI, Kager PA, Fatal human rabies due to Duvenhage virus from a bat in Kenya: failure of treatment with coma-induction, ketamine, and antiviral drugs. PLOS NEGLECT TROP D 2009;3 (7):e428 [PubMed]
Vis JC, Timmermans J, Post MC, Budts W, Schepens MAAM, Thijs V, Schonewille WJ, de Bie RMA, Plokker HWM, Tijssen JGP, Mulder BJM, Increased prevalence of migraine in Marfan syndrome. INT J CARDIOL 2009;136 (3):330-334 [PubMed]
de Bie RMA, Surie S, Kloek JJ, Biervliet JD, de Beaumont EM, Rutten PMMJ, Smeding HMM, Bresser P, Tijssen MAJ, Chorea in Adults after Pulmonary Endarterectomy with Deep Hypothermia and Circulatory Arrest. ANN INTERN MED 2008;149 (11):842 [PubMed]
Visanji NP, de Bie RMA, Johnston TH, McCreary AC, Brotchie JM, Fox SH, The nociceptin/orphanin FQ (NOP) receptor antagonist J-113397 enhances the effects of levodopa in the MPTP-lesioned nonhuman primate model of Parkinson's disease. MOVEMENT DISORD 2008;23 (13):1922-1925 [PubMed]
Zadikoff C, Fox SH, Tang-Wai DF, Thomsen T, de Bie RMA, Wadia P, Miyasaki J, Duff-Canning S, Lang AE, Marras C, A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease. MOVEMENT DISORD 2008;23 (2):297-299 [PubMed]
Beukers RJ, Weisfelt M, de Bie RMA, Neurosurgery at an earlier stage of Parkinson disease. NEUROLOGY 2007;69 (8):811-2; author reply 812 [PubMed]
de Bie RMA, Chen R, Lang AE, Orthostatic tremor in progressive supranuclear palsy. MOVEMENT DISORD 2007;22 (8):1192-1194 [PubMed]
de Bie RMA, Gladstone RM, Strafella AP, Ko JH, Lang AE, Manganese-induced Parkinsonism associated with methcathinone (Ephedrone) abuse. ARCH NEUROL-CHICAGO 2007;64 (6):886-889 [PubMed]
de Bie RMA, Miyasaki J, Lang AE, Fox SH, Clinical practice regarding dopamine-agonist use and driving in Parkinson's disease. CAN J NEUROL SCI 2007;34 (4):438-442 [PubMed]
Esselink RAJ, de Bie RMA, de Haan RJ, Schuurman PR, van den Munckhof P, Speelman JD, A randomized trial comparing unilateral pallidotomy with bilateral subthalamic nucleus stimulation in PD: perspectives for future stimulation in clinical practice. PROGR NEUROTHER NEUROPSYCHOPHARMACOL 2007;2 (2):13-26
Esselink RAJ, de Bie RMA, de Haan RJ, Steur ENHJ, Beute GN, Portman AT, Schuurman PR, Bosch DA, Speelman JD, Unilateral pallidotomy versus bilateral subthalamic nucleus stimulation in Parkinson's disease: one year follow-up of a randomised observer-blind multi centre trial. ACTA NEUROCHIR 2006;148 (12):1247-55; discussion 1255 [PubMed]
Esselink RAJ, de Bie RMA, Schuurman PR, Bosch DA, Speelman JD, Parkinson's disease and deep brain stimulation. AGING HEALTH 2006;2 (3):473-487
Post B, Merkus MP, de Bie RMA, de Haan RJ, Speelman JD, Unified Parkinson's disease rating scale motor examination: are ratings of nurses, residents in neurology, and movement disorders specialists interchangeable?. MOVEMENT DISORD 2005;20 (12):1577-1584 [PubMed]
Esselink RAJ, de Bie RMA, de Haan RJ, Lenders MWPM, Nijssen PCG, Staal MJ, Smeding HMM, Schuurman PR, Bosch DA, Speelman JD, Unilateral pallidotomy versus bilateral subthalamic nucleus stimulation in PD - A randomized trial. NEUROLOGY 2004;62 (2):201-207 [PubMed]
de Bie RMA, Speelman JD, Ziekte van Parkinson: diagnose, beloop en behandeling. MOD MED 2003;3:205-207
de Bie RMA, Speelman JD, Schuurman PR, On Johnson M, Wester K: Full remission of tardive dyskinesia following general anaesthesia. J NEUROL 2003;250 (3):356; author reply 356 [PubMed]
de Bie RMA. Stereotactic pallidotomy in Parkinson's disease. S.l.: s.n.; 2002. 128p. ISBN 90-9015420-5 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Bosch DA, Vermeulen M; copromotor(s): de Haan RJ, Speelman JD)
de Bie RMA, de Haan RJ, Schuurman PR, Esselink RAJ, Bosch DA, Speelman JD, Morbidity and mortality following pallidotomy in Parkinson's disease - A systematic review. NEUROLOGY 2002;58 (7):1008-1012 [PubMed]
de Bie RMA, Schuurman PR, Esselink RAJ, Bosch DA, Speelman JD, Bilateral pallidotomy in Parkinson's disease: A retrospective study. MOVEMENT DISORD 2002;17 (3):533-538 [PubMed]
Speelman JD, Foncke E, Vergouwen MDI, de Bie RMA, Bosch DA, Chirurgische behandeling van dystonie. NED TIJDSCHR NEUROL 2002;- (5):384-e.v.
Speelman JD, Schuurman R , de Bie RMA, Esselink RAJ, Bosch DA, Stereotactic neurosurgery for tremor. MOVEMENT DISORD 2002;17 (Suppl. 3):S84-S88 [PubMed]
de Bie RM, Schuurman PR, Bosch DA, de Haan RJ, Schmand B, Speelman JD, Outcome of unilateral pallidotomy in advanced Parkinson's disease: cohort study of 32 patients. J NEUROL NEUROSUR PS 2001;71 (3):375-382 [PubMed]
Speelman JD, Esselink RA, Schuurman PR, de Bie RM, Bosch DA, Stereotactische neurochirurgie bij de behandeling van de ziekte van Parkinson. NED TIJDSCHR GENEESKD 2001;145 (18):853-858 [PubMed]
Schmand B, de Bie RM, Koning-Haanstra M, de Smet JS, Speelman JD, van Zomeren AH, Unilateral pallidotomy in PD: a controlled study of cognitive and behavioral effects. The Netherlands Pallidotomy Study (NEPAS) group. NEUROLOGY 2000;54 (5):1058-1064 [PubMed]
Schuurman PR, Bosch DA, Bossuyt PM, Bonsel GJ, van Someren EJ, de Bie RM, Merkus MP, Speelman JD, A comparison of continuous thalamic stimulation and thalamotomy for suppression of severe tremor. NEW ENGL J MED 2000;342 (7):461-468 [PubMed]
de Bie RM, de Haan RJ, Nijssen PC, Rutgers AW, Beute GN, Bosch DA, Haaxma R, Schmand B, Schuurman PR, Staal MJ, Speelman JD, Unilateral pallidotomy in Parkinson's disease: a randomised, single-blind, multicentre trial. LANCET 1999;354 (9191):1665-1669 [PubMed]
de Bie RM, Schuurman PR, de Haan PS, Bosch DA, Speelman JD, Unilateral pallidotomy in advanced Parkinson's disease: a retrospective study of 26 patients. MOVEMENT DISORD 1999;14 (6):951-957 [PubMed]
de Bie RM, Speelman JD, Schuurman PR, Bosch DA, Transient hiccups after posteroventral pallidotomy for Parkinson's disease. J NEUROL NEUROSUR PS 1999;67 (1):124-125 [PubMed]
Schuurman PR, de Bie RM, Majoie CB, Speelman JD, Bosch DA, A prospective comparison between three-dimensional magnetic resonance imaging and ventriculography for target-coordinate determination in frame-based functional stereotactic neurosurgery. J NEUROSURG 1999;91 (6):911-914 [PubMed]
Schuurman PR, Speelman JD, de Bie RM, Bosch DA, Neurochirurgische stereotactische behandeling bij de ziekte van Parkinson. NED TIJDSCHR GENEESKD 1998;142 (1):10-14 [PubMed]
Speelman JD, Schuurman PR, de Bie RM, Bosch DA, Thalamic surgery and tremor. MOVEMENT DISORD 1998;13 (Suppl. 3):103-106 [PubMed]
Schuurman PR, de Bie RM, Speelman JD, Bosch DA, Bilateral posteroventral pallidotomy in advanced Parkinson's disease in three patients. MOVEMENT DISORD 1997;12 (5):752-755 [PubMed]
Schuurman PR, de Bie RM, Speelman JD, Bosch DA, Posteroventral pallidotomy in movement disorders. ACTA NEUROCHIR 1997;68 (Suppl.):14-17 [PubMed]
Key publications

Odekerken VJJ, van Laar T, Staal MJ, Mosch A, Hoffmann CFE, Nijssen PCG, Beute GN, van Vugt JPP, Lenders MWPM, Contarino MF, Mink MSJ, Bour LJ, van den Munckhof P, Schmand BA, de Haan RJ, Schuurman PR, de Bie RMA, Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial. LANCET NEUROL 2013;12 (1):37-44 [PubMed]
Velseboer DC, de Haan RJ, Wieling W, Goldstein DS, de Bie RMA, Prevalence of orthostatic hypotension in Parkinson's disease: a systematic review and meta-analysis. PARKINSONISM RELAT D 2011;17 (10):724-729 [PubMed]
Odekerken VJJ, Boel JA, Schmand BA, de Haan RJ, Figee M, van den Munckhof P, Schuurman PR, de Bie RMA [Contributors: de Bie RMA, Bour L, Contarino MF, de Haan RJ, Iwan M, Mink MSJ, van den Munckhof P, Odekerken VJJ , Postma M, Schmand BA, Scholten MN, Schuurman PR, van Laar T, van Dijk JMC, Hoffmann CFE, Mosch A, Beute GN, Nijssen PCG, van Asseldonk T, Lenders MWPM, van Vugt JPP]] , GPi vs STN deep brain stimulation for Parkinson disease: Three-year follow-up. NEUROLOGY 2016;86 (8):755-761 [PubMed]
Velseboer DC, Broeders M, Post B, van Geloven N, Speelman JD, Schmand B, de Haan RJ, de Bie RMA, Prognostic factors of motor impairment, disability, and quality of life in newly diagnosed PD. NEUROLOGY 2013;80 (7):627-633 [PubMed]
Odekerken VJJ, Boel JA, Geurtsen GJ, Schmand BA, Dekker IP, de Haan RJ, Schuurman PR, de Bie RMA [Contributors: Odekerken VJJ, Boel JA, van Laar T, Staal MJ, Mosch A, Hoffmann CFE, Nijssen PCG, Beute GN, van Vugt JPP, Mathieu WPM, Contarino MF, Mink MSJ, Bour LJ, van den Munckhof P, Geurtsen GJ, Schmand BA, de Haan RJ, Schuurman PR, de Bie RMA]] , Neuropsychological outcome after deep brain stimulation for Parkinson disease. NEUROLOGY 2015;84 (13):1355-1361 [PubMed]


All Publications

Curriculum Vitae

2017- Professor of neurology
2011- Group leader Movement Disorders, Department of Neurology, Academic Medical Center, University of Amsterdam

2006- Neurologist, Movement Disorders

2005-2006 Clinical fellowship Movement Disorders, Toronto Western Hospital, Toronto, Ontario, Canada
1999-2005 Board Certification Neurology, Academic Medical Center, Amsterdam
1997-2002 Doctorate (Ph.D.), “Stereotactic pallidotomy in Parkinson’s disease”, University of Amsterdam
1993-1996 Medical Degree (M.D.)
Faculty of Medicine, University of Amsterdam

Research programmes

Movement Disorders

The Department of Neurology performs clinical and translational research within three research themes: infection & inflammation, cerebrovascular disorders, and movement disorders. The themes are imbedded in the nine translational research programs of Amsterdam Neuroscience, the research institute of neuroscience investigators in the Amsterdam area. All staff members of the Department of Neurology are involved in research and collaborate within Neuroscience Amsterdam, with other academic and non-academic hospitals, and with international research groups.

The research of the movement disorders group focuses on improving treatment, diagnosis, and insight in pathophysiology of movement disorders such as Parkinson’s disease, tremor, myoclonus, and dystonia. The group has a strong clinical research infrastructure to conduct large cohort studies and randomized controlled trials on interventions ranging from medication to botulinum toxin injections and Deep Brain Stimulation (DBS), aimed at solving burning clinical questions. Advanced neurophysiological measures and analysis techniques, intraoperative microrecording from nuclei situated deeply in the brain, and (functional) MRI are available to answer important diagnostic and pathophysiological research questions. The group is embedded in the neurodegeneration program of Amsterdam Neuroscience.

My research focuses on the improvement of treatment of Parkinson’s disease, including Deep Brain Stimulation (DBS), pharmacological treatment, and non-motor symptoms. In 2013, we completed a multicenter study that demonstrated the superiority of STN DBS compared to GPi DBS. Currently, my team is conducting a trial that compares DBS with Continuous Intrajejunal Levodopa Infusion for the treatment of advanced Parkinson’s disease (www.investamc.nl). We also conduct research to improve DBS hardware features ― e.g., steering DBS current.

In addition, I have initiated and lead a large RCT to assess a possible disease modifying effect of levodopa in early Parkinson’s disease (www.leapamc.nl). To recruit the 446 patients in 61 Dutch hospitals for this study, I established a National Clinical Research Network. In the same network, we investigate if cholinesterase inhibitors delay the progression of minor hallucinations to psychosis in Parkinson’s disease (www.chevalstudie.nl).

In collaboration with prof. Schmand, neuropsychologist, I investigate cognition in Parkinson’s disease. Notable projects include (1) cognitive impairment in the course of the disease and (2) an international collaborative Parkinson’s disease-MCI validation project directed by the AMC group, and (3) cognitive and psychiatric effects of DBS for Parkinson's disease. I have been following an incident cohort of Parkinson’s disease patients for 10 years now, which provides internationally acclaimed unique data regarding prognostication and disease course. I cooperate successfully with Drs. Barker and Williams-Gray, Cambridge, in projects regarding disease progression and prognostic models for PD.

Faculty
Prof. dr. R.M.A. de Bie
Dr. J.M. Dijk
Dr. J.H.T.M. Koelman
Dr. V.J.J. Odekerken
Dr. W.V. Potters PhD
Dr. A.F. van Rootselaar MD PhD

PhD Students
Drs. J.A. Boel (Universiteit van Amsterdam)
M. Bot MD
Drs. T.R. Brinke
H.L. Frequin
Drs. J. Hoogland
Drs. D. van Poppelen
Drs. S.R. Suwijn
Drs. D.C. Velseboer
Drs. C.V.M. Verschuur

Others
S. Van der Meijde - Bessems
S. de Vries

Prof. dr. P.R. Schuurman (deep brain stimulation)

Other research related activities
  • None reported
Current research funding
  • ECMT
  • GE Healthcare Limited
  • Kinetics Foundation
  • Parkinson Patienten Vereniging
  • Stichting Parkinson Nederland
  • ZonMw