• Principal Investigator
  • Male

Prof. dr. H.N. Caron MD PhD

Position: Professor
Main activities: Research, Patient care
Specialisation: paediatric oncology
foto H.N. Caron is one of the AMC Principal Investigators
Focus of research:

To improve the cure rates for children with cancer by developping new treatments and better risk stratification of current treatments and also to reduce side-effects for survivors of childhoodcancer by maximising the evidence-base for treatment decisions and guidelines for early detection and intervention.

AMC themes: Oncology, Public Health & Epidemiology
Departments: Paediatrics: Oncology
Bate-Eya LT. Neuroblastoma: Crossing borders in targeted therapy. S.l.: s.n.; 2017. 233p. ISBN 978-94-6299-631-1 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Molenaar JJ , Dolman MEM)
Bate-Eya LT, Gierman HJ, Ebus ME, Koster J, Caron HN, Versteeg R, Dolman MEM, Molenaar JJ, Enhancer of zeste homologue 2 plays an important role in neuroblastoma cell survival independent of its histone methyltransferase activity. EUR J CANCER 2017;75:63-72 [PubMed]
Font-Gonzalez A, Feijen ELAM, Geskus RB, Dijkgraaf MGW, van der Pal HJH, Heinen RC, Jaspers MW, van Leeuwen FE, Reitsma JBJ, Caron HN, Sieswerda E, Kremer LC, Risk and associated risk factors of hospitalization for specific health problems over time in childhood cancer survivors: a medical record linkage study. CANCER MED-US 2017;6 (5):1123-1134 [PubMed]
Jagt CT. Improving aspects of palliative care for children. S.l.: s.n.; 2017. 185p. ISBN 978-94-028-0829-2 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, Grootenhuis MA; copromotor(s): )
Jagt-van Kampen CT, Kars MC, Colenbrander DA, Bosman DK, Grootenhuis MA, Caron HN, Schouten-van Meeteren AYN, A prospective study on the characteristics and subjects of pediatric palliative care case management provided by a hospital based palliative care team. BMC PALLIAT CARE 2017;16 (1):1 [PubMed]
Kraal K, Blom T, van Noesel M, Kremer L, Caron H, Tytgat G, van der Pal H, Treatment and outcome of neuroblastoma with intraspinal extension: A systematic review. PEDIATR BLOOD CANCER 2017;64 (8):e26451 [PubMed]
Kraal KCJM. Optimising therapy with 131I-MIBG for neuroblastoma patients and for neuroblastoma patients with intraspinal extension. S.l.: s.n.; 2017. 270p. ISBN 978-94-6233-520-2 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Tytgat GAM, van Noesel MM)
Kraal KCJM , Bleeker GM, van Eck-Smit BLF, van Eijkelenburg NKA, Berthold F, van Noesel MM, Caron HN, Tytgat GAM, Feasibility, toxicity and response of upfront metaiodobenzylguanidine therapy therapy followed by German Pediatric Oncology Group Neuroblastoma 2004 protocol in newly diagnosed stage 4 neuroblastoma patients. EUR J CANCER 2017;76:188-196 [PubMed]
Moreno L, Caron H, Geoerger B, Eggert A, Schleiermacher G, Brock P, Valteau-Couanet D, Chesler L, Schulte JH, de Preter K, Molenaar J, Schramm A, Eilers M, van Maerken T, Johnsen JI, Garrett M, George SL, Tweddle DA, Kogner P, Berthold F, Koster J, Barone G, Tucker ER, Marshall L, Herold R, Sterba J, Norga K, Vassal G, Pearson ADJ, Accelerating drug development for neuroblastoma - New Drug Development Strategy: an Innovative Therapies for Children with Cancer, European Network for Cancer Research in Children and Adolescents and International Society of Paediatric Oncology Europe Neuroblastoma project. EXPERT OPIN DRUG DIS 2017;12 (8):801-811 [PubMed]
Schepers SA. Changing pediatric cancer care: development and implementation of electronic patient and parent reported outcomes. S.l.: s.n.; 2017. 236p. ISBN 978-94-6233-479-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Grootenhuis MA, Caron HN; copromotor(s): Verhaak CM)
Schepers SA, Sint Nicolaas SM, Haverman L , Wensing M, Schouten van Meeteren AYN, Veening MA, Caron HN, Hoogerbrugge PM, Kaspers GJL, Verhaak CM, Grootenhuis MA, Real-world implementation of electronic patient-reported outcomes in outpatient pediatric cancer care. PSYCHO-ONCOLOGY 2017;26 (7):951-959 [PubMed]
Schoot RA, Hol MLF, Merks JHM, Suttie M, Slater O, van Lennep M, Hopman SMJ, Dunaway D, Syme-Grant J, Smeele LE, Zwinderman KH, Caron HN, Hammond P, Facial asymmetry in head and neck rhabdomyosarcoma survivors. PEDIATR BLOOD CANCER 2017;64 (10):e26508 [PubMed]
Verly IRN, van Kuilenburg ABP, Abeling NGGM, Goorden SMI, Fiocco M, Vaz FM, van Noesel MM, Zwaan CM, Kaspers GL, Merks JHM, Caron HN, Tytgat GAM, Catecholamines profiles at diagnosis: Increased diagnostic sensitivity and correlation with biological and clinical features in neuroblastoma patients. EUR J CANCER 2017;72:235-243 [PubMed]
Bate-Eya LT, den Hartog IJM, van der Ploeg I, Schild L, Koster J, Santo EE, Westerhout EM, Versteeg R, Caron HN, Molenaar JJ, Dolman MEM, High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition. ONCOTARGET 2016;7 (19):27946-27958 [PubMed]
Clement SC. Endocrine disorders in childhood cancer survivors: More answers, more questions. S.l.: s.n.; 2016. 327p. ISBN 978-94-6233-255-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): van Santen HM, Kremer LCM)
Clement SC, Schoot RA, Slater O, Chisholm JC, Abela C, Balm AJM, van den Brekel MW, Breunis WB, Chang YC, Davila Fajardo R , Dunaway D, Gajdosova E, Gaze MN, Gupta S, Hartley B, Kremer LCM, van Lennep M, Levitt GA, Mandeville HC, Pieters BR, Saeed P, Smeele LE, Strackee SD, Ronckers CM, Caron HN, van Santen HM, Merks JHM, Endocrine disorders among long-term survivors of childhood head and neck rhabdomyosarcoma. EUR J CANCER 2016;54:1-10 [PubMed]
Clement SC, Schouten-van Meeteren AYN, Boot AM, Claahsen-van der Grinten HL, Granzen B, Sen Han K, Janssens GO, Michiels EM, van Trotsenburg ASP, Vandertop WP, van Vuurden DG, Kremer LCM, Caron HN, van Santen HM, Prevalence and Risk Factors of Early Endocrine Disorders in Childhood Brain Tumor Survivors: A Nationwide, Multicenter Study. J CLIN ONCOL 2016;34 (36):4362-4370 [PubMed]
de Ruiter MA. Impact of a pediatric brain tumor: Research into neurocognitive late effects and psychosocial consequences and the evaluation of a potential intervention. S.l.: s.n.; 2016. 201p. ISBN 9789462334700 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Grootenhuis MA, Oosterlaan J; copromotor(s): Caron HN, Schouten-van Meeteren AYN)
de Ruiter MA, Oosterlaan J, Schouten-van Meeteren AYN, Maurice-Stam H, van Vuurden DG, Gidding C, Beek LR, Granzen B, Caron HN, Grootenhuis MA, Neurofeedback ineffective in paediatric brain tumour survivors: Results of a double-blind randomised placebo-controlled trial. EUR J CANCER 2016;64:62-73 [PubMed]
Font-Gonzalez A. Health problems in childhood cancer survivors: Linkage studies and guideline development. S.l.: s.n.; 2016. 260p. ISBN 9789090300313 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Kremer LCM, Tissing WJE)
Font-Gonzalez A, Feijen EL, Sieswerda E, van Dulmen-den Broeder E, Grootenhuis M, Maurice-Stam H, Caron H, Essink-Bot ML, van der Pal H, Geskus R, Kremer L, Social outcomes in adult survivors of childhood cancer compared to the general population: linkage of a cohort with population registers. PSYCHO-ONCOLOGY 2016;25 (8):933-941 [PubMed]
Keizer MP, Kamp AM, Aarts C, Geisler J, Caron HN, van de Wetering MD, Wouters D, Kuijpers TW, The High Prevalence of Functional Complement Defects Induced by Chemotherapy. FRONT IMMUNOL 2016;7:420 [PubMed]
Kraal K, Blom T, Tytgat L, van Santen H, van Noesel M, Smets A, Bramer J, Caron H, Kremer L, van der Pal H, Neuroblastoma With Intraspinal Extension: Health Problems in Long-Term Survivors. PEDIATR BLOOD CANCER 2016;63 (6):990-996 [PubMed]
Pearson ADJ, Herold R, Rousseau R, Copland C, Bradley-Garelik B, Binner D, Capdeville R, Caron H, Carleer J, Chesler L, Geoerger B, Kearns P, Marshall LV, Pfister SM, Schleiermacher G, Skolnik J, Spadoni C, Sterba J, van den Berg H, Uttenreuther-Fischer M, Witt O, Norga K, Vassal G [Contributors: Georger B, Iannone R, Jakacki R, Russo M]] , Implementation of mechanism of action biology-driven early drug development for children with cancer. EUR J CANCER 2016;62:124-131 [PubMed]
Schoot RA, Saeed P, Freling NJ, Blank LECM, Pieters BR, van der Grient JNB, Strackee SD, Bras J, Caron HN, Merks JHM, Local Resection and Brachytherapy for Primary Orbital Rhabdomyosarcoma: Outcome and Failure Pattern Analysis. OPHTHAL PLAST RECONS 2016;32 (5):354-360 [PubMed]
Schoot RA, Theunissen EAR, Slater O, Lopez-Yurda M, Zuur CL, Gaze MN, Chang YC, Mandeville HC, Gains JE, Rajput K, Pieters BR, Davila Fajardo R , Talwar R, Caron HN, Balm AJM, Dreschler WA, Merks JHM, Hearing loss in survivors of childhood head and neck rhabdomyosarcoma: a long-term follow-up study. CLIN OTOLARYNGOL 2016;41 (3):276-283 [PubMed]
Schoot RA, van de Wetering MD, Stijnen T, Tissing WJE, Michiels E, Abbink FCH, Raphael MF, Heij HA, Zwaan M, Lieverst JA, Caron HN, van Ommen H, Prevalence of Symptomatic and Asymptomatic Thrombosis in Pediatric Oncology Patients With Tunneled Central Venous Catheters. PEDIATR BLOOD CANCER 2016;63 (8):1438-1444 [PubMed]
Sieswerda E, Font-Gonzalez A, Reitsma JB, Dijkgraaf MGW, Heinen RC, Jaspers MW, van der Pal HJ, van Leeuwen FE, Caron HN, Geskus RB, Kremer LC, High Hospitalization Rates in Survivors of Childhood Cancer: A Longitudinal Follow-Up Study Using Medical Record Linkage. PLOS ONE 2016;11 (7):e0159518 [PubMed]
Sint Nicolaas SM, Schepers SA, Hoogerbrugge PM, Caron HN, Kaspers GJL, van den Heuvel-Eibrink MM, Grootenhuis MA, Verhaak CM, Screening for Psychosocial Risk in Dutch Families of a Child With Cancer: Reliability, Validity, and Usability of the Psychosocial Assessment Tool. J PEDIATR PSYCHOL 2016;41 (7):810-819 [PubMed]
van de Wetering MD, Vossen MTM, Jansen MH, Caron HN, Kuijpers TW, Varicella vaccination in pediatric oncology patients without interruption of chemotherapy. J CLIN VIROL 2016;75:47-52 [PubMed]
van Dijk IWEM, van der Pal HJH, van Os RM, Roos YBWEM, Sieswerda E, van Dalen EC, Ronckers CM, Oldenburger F, van Leeuwen FE, Caron HN, Koning CCE, Kremer LCM, Risk of Symptomatic Stroke After Radiation Therapy for Childhood Cancer: A Long-Term Follow-Up Cohort Analysis. INT J RADIAT ONCOL 2016;96 (3):597-605 [PubMed]
van Wezel E. Minimal residual disease monitoring in neuroblastoma. S.l.: s.n.; 2016. 199p. ISBN 978-94-6169-835-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van der Schoot CE, Caron HN; copromotor(s): Tytgat GAM)
van Wezel EM, Decarolis B, Stutterheim J, Zappeij-Kannegieter L, Berthold F, Schumacher-Kuckelkorn R, Simon T, Fiocco M, van Noesel MM, Caron HN, van der Schoot CE, Hero B, Tytgat GAM, Neuroblastoma messenger RNA is frequently detected in bone marrow at diagnosis of localised neuroblastoma patients. EUR J CANCER 2016;54:149-158 [PubMed]
Aminkeng F, Bhavsar AP, Visscher H, Rassekh SR, Li Y, Lee JW, Brunham LR, Caron HN, van Dalen EC, Kremer LC, van der Pal HJ, Amstutz U, Rieder MJ, Bernstein D, Carleton BC, Hayden MR, Ross CJD [Contributors: Hayden MR, Carleton BC, Ross CJD, MacLeod S, Smith A, Hildebrand C, Ghannadan R, Rassekh SR, Visscher H, Aminkeng F, Miao F, Higginson M, Massah N, Borrie A, Amstutz U, Hughes S, Shaw K, Dhoot S, Bhavsar AP, Li Y, Lee JW, Kowalec K, Stortz J, Bendyshe-Walton T, Waltrip D, Bader R, Nijssen-Jordan C, Johnson D, Verbeek L, Kaczowka R, Stevenson P, Zhuwaki C, Grundy P, Stobart K, Wilson B, Desai S, Spavor M, Churcher L, Chow T, Hall K, Honcharik N, Israels S, Chan S, Garnham B, Staub M, 't Jong G, Rieder MJ, Malkin B, Portwine C, Cranston A, Koren G, Ito S, Nathan P, Greenberg M, Bournissen FG, Inoue M, Sakaguchi S, Tanaka T, Fujii H, Ogawa M, Ingram R, Kamiya T, Karande S, Ghayoori S, Silva M, Willing S, Vaillancourt R, Johnston D, Mankoo H, Wong E, Wilson B, O'Connor L, Hui C, Yuen C, Bussières JF, Lebel D, Barret P, Clauson A, Courbon E, Cerruti L, Jabado N, Santo AE, Nagy M, Murray M, Boliver D, Tiller M, Osborne CA, Goodyear L, Bowes L, Kean N, Hand J]] , A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer. NAT GENET 2015;47 (9):1079-1084 [PubMed]
Ariës IM, van den Dungen RE, Koudijs MJ, Cuppen E, Voest E, Molenaar JJ, Caron HN, Pieters R, den Boer ML, Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance. HAEMATOLOGICA 2015;100 (4):e132-e136 [PubMed]
Bleeker G, Heijkoop D, Kremer LC, Smets AM, Deurloo EE, van Eck-Smit BL, Caron HN, Tytgat GA, Dalen ECv, Systematic Literature Review of Imaging Definitions for Detection of Bone and Bone Marrow Metastases in Neuroblastoma Patients. J BONE MARROW RES 2015;3 (3):1-13
Bleeker G, Tytgat GAM, Adam JA, Caron HN, Kremer LCM, Hooft L, van Dalen EC, 123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma. COCHRANE DB SYST REV 2015;2015 (9):CD009263 [PubMed]
Bleeker G, van Eck-Smit BL, Zwinderman KH, Versteeg R, van Noesel MM, Kam BL, Kaspers GJ, van Schie A, Kreissman SG, Yanik G, Hero B, Schmidt M, Laureys G, Lambert B, Øra I, Schulte JH, Caron HN, Tytgat GA, MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis. EUR J NUCL MED MOL I 2015;42 (2):222-230 [PubMed]
Clement SC, van Rijn RR, van Eck-Smit BLF, van Trotsenburg ASP, Caron HN, Tytgat GAM, van Santen HM, Long-term efficacy of current thyroid prophylaxis and future perspectives on thyroid protection during I-131-metaiodobenzylguanidine treatment in children with neuroblastoma. EUR J NUCL MED MOL I 2015;42 (5):706-715 [PubMed]
Dolman MEM, Poon E, Ebus ME, den Hartog IJM, van Noesel CJM, Jamin Y, Hallsworth A, Robinson SP, Petrie K, Sparidans RW, Kok RJ, Versteeg R, Caron HN, Chesler L, Molenaar JJ, Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma. CLIN CANCER RES 2015;21 (22):5100-5109 [PubMed]
Dolman MEM, van der Ploeg I, Koster J, Bate-Eya LT, Versteeg R, Caron HN, Molenaar JJ, DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells. PLOS ONE 2015;10 (12):e0145744 [PubMed]
Eleveld TF, Oldridge DA, Bernard V, Koster J, Daage LC, Diskin SJ, Schild L, Bentahar NB, Bellini A, Chicard M, Lapouble E, Combaret V, Legoix-Né P, Michon J, Pugh TJ, Hart LS, Rader J, Attiyeh EF, Wei JS, Zhang S, Naranjo A, Gastier-Foster JM, Hogarty MD, Asgharzadeh S, Smith MA, Guidry Auvil JM, Watkins TBK, Zwijnenburg DA, Ebus ME, van Sluis P, Hakkert A, van Wezel E, van der Schoot CE, Westerhout EM, Schulte JH, Tytgat GA, Dolman MEM, Janoueix-Lerosey I, Gerhard DS, Caron HN, Delattre O, Khan J, Versteeg R, Schleiermacher G, Molenaar JJ, Maris JM, Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations. NAT GENET 2015;47 (8):864-871 [PubMed]
Feijen EAM. Childhood cancer survivors: cardiac disease & social outcomes. S.l.: s.n.; 2015. 239p. ISBN 978-94-92290-00-7 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Kremer LCM)
Feijen EAM, Leisenring WM, Stratton KL, Ness KK, van der Pal HJH, Caron HN, Armstrong GT, Green DM, Hudson MM, Oeffinger KC, Robison LL, Stovall M, Kremer LCM, Chow EJ, Equivalence Ratio for Daunorubicin to Doxorubicin in Relation to Late Heart Failure in Survivors of Childhood Cancer. J CLIN ONCOL 2015;33 (32):3774-3780 [PubMed]
Kraal KCJM, Tytgat GAM, van Eck-Smit BLF, Kam B, Caron HN, van Noesel M, Upfront treatment of high-risk neuroblastoma with a combination of 131I-MIBG and topotecan. PEDIATR BLOOD CANCER 2015;62 (11):1886-1891 [PubMed]
Schoot RA. Childhood cancer treatment optimization in rhabdomyosarcoma and supportive care. S.l.: s.n.; 2015. 371p. ISBN 978-90-9029115-4 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Merks JHM, van de Wetering MD, van Ommen CH)
Schoot RA, Slater O, Ronckers CM, Zwinderman AH, Balm AJM, Hartley B, van den Brekel MW, Gupta S, Saeed P, Gajdosova E, Pieters BR, Gaze MN, Mandeville HC, Fajardo RD, Chang YCi, Gains JE, Strackee SD, Dunaway D, Abela C, Mason C, Smeele LE, Chisholm JC, Levitt GA, Kremer LCM, Grootenhuis MA, Maurice-Stam H, Stiller CA, Hammond P, Caron HN, Merks JHM, Adverse events of local treatment in long-term head and neck rhabdomyosarcoma survivors after external beam radiotherapy or AMORE treatment. EUR J CANCER 2015;51 (11):1424-1434 [PubMed]
Schoot RA, van Ommen CH, Stijnen T, Tissing WJE, Michiels E, Abbink FCH, Raphael MF, Heij HA, Lieverst JA, Spanjaard L, Zwaan CM, Caron HN, van de Wetering MD, Prevention of central venous catheter-associated bloodstream infections in paediatric oncology patients using 70% ethanol locks: A randomised controlled multi-centre trial. EUR J CANCER 2015;51 (14):2031-2038 [PubMed]
Sieswerda E, Font-Gonzalez A, Dijkgraaf MGW, Geskus RB, Heinen RC, van der Pal HJ, van Leeuwen FE, Caron HN, Kremer LC, Reitsma JB, Studying Hospitalizations and Mortality in the Netherlands: Feasible and Valid Using Two-Step Medical Record Linkage with Nationwide Registers. PLOS ONE 2015;10 (7):e0132444 [PubMed]
van Dalen EC, de Lijster MS, Leijssen LGJ, Michiels EMC, Kremer LCM, Caron HN, Aronson DC, Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children. COCHRANE DB SYST REV 2015;2015 (1):CD008403 [PubMed]
van der Pal HJ, van Dijk IW, Geskus RB, Kok WE, Koolen M, Sieswerda E, Oldenburger F, Koning CC, van Leeuwen FE, Caron HN, Kremer LC, van Dalen EC, Valvular abnormalities detected by echocardiography in 5-year survivors of childhood cancer: a long-term follow-up study. INT J RADIAT ONCOL 2015;91 (1):213-222 [PubMed]
van Santen HM, Geskus RB, Raemaekers S, van Trotsenburg ASP, Vulsma T, van der Pal HJH, Caron HN, Kremer LCM, Changes in body mass index in long-term childhood cancer survivors. CANCER-AM CANCER SOC 2015;121 (23):4197-4204 [PubMed]
van Wezel EM, Stutterheim J, Vree F, Zappeij-Kannegieter L, Decarolis B, Hero B, Berthold F, Schumacher-Kuckelkorn R, Simon T, Fiocco M, Voermans C, van Noesel MM, Caron HN, van der Schoot CE, Tytgat GAM [Contributors: Koehl U, Schulte JH, Niggli F, Fruhwald MC, Niemeyer CM, Bode U, Schilling FH, Schultz C, Graf N, Nathrath M, Schmid I]] , Minimal residual disease detection in autologous stem cell grafts from patients with high risk neuroblastoma. PEDIATR BLOOD CANCER 2015;62 (8):1368-1373 [PubMed]
van Wezel EM, Zwijnenburg D, Zappeij-Kannegieter L, Bus E, van Noesel MM, Molenaar JJ, Versteeg R, Fiocco M, Caron HN, van der Schoot CE, Koster J, Tytgat GAM, Whole-genome sequencing identifies patient-specific DNA minimal residual disease markers in neuroblastoma. J MOL DIAGN 2015;17 (1):43-52 [PubMed]
Visscher H, Rassekh SR, Sandor GS, Caron HN, van Dalen EC, Kremer LC, van der Pal HJ, Rogers PC, Rieder MJ, Carleton BC, Hayden MR, Ross CJ [Contributors: Hayden M, Carleton B, Ross C, MacLeod S, Wasserman W, Mitton C, Smith A, Hildebrand C, Pastrana LC, Ghannadan R, Rassekh R, Miao F, Visscher H, Higginson M, Borrie A, Amstutz U, Bhavsar A, Nijssen-Jordan C, Johnson D, Verbeek L, Kaczowka R, Grundy P, Stobart K, Wilson B, Desai S, Spavor M, Churcher L, Chow T, Hall K, Honcharik N, Israels S, Chan S, Garnham B, Staub M, Rieder M, Malkin B, Portwine C, Cranston A, Koren G, Ito S, Nathan P, Greenberg M, Bournissen FG, Inoue M, Sakaguchi S, Tanaka T, Fujii H, Ogawa M, Ingram R, Kamiya T, Karande S, Silva M, Willing S, Vaillancourt R, Elliott-Miller P, Johnston D, Mankoo H, Wong E, Wilson B, O'Connor L, Maher M, Bussières JF, Lebel D, Barret P, Closon A, Phillips M, Jabado N, Espirito Santo A, Nagy M, Murray M, Boliver D, Tiller M, Osborne CA, Goodyear L, Hand J, Bowes L, Kean N]] , Genetic variants in SLC22A17 and SLC22A7 are associated with anthracycline-induced cardiotoxicity in children. PHARMACOGENOMICS 2015;16 (10):1065-1076 [PubMed]
Bate-Eya LT, Ebus ME, Koster J, den Hartog IJM, Zwijnenburg DA, Schild L, van der Ploeg I, Dolman MEM, Caron HN, Versteeg R, Molenaar JJ, Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours. EUR J CANCER 2014;50 (3):628-637 [PubMed]
Bleeker G. The use of both diagnostic and therapeutic MIBG in neuroblastoma patients. s.l.: s.n.; 2014. 328p. ISBN 9789090282176 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, van Eck-Smit BL; copromotor(s): Tytgat GAM)
Clement SC, Meeteren AYNSv, Kremer LCM, van Trotsenburg ASP, Caron HN, van Santen HM, High prevalence of early hypothalamic-pituitary damage in childhood brain tumor survivors: need for standardized follow-up programs. PEDIATR BLOOD CANCER 2014;61 (12):2285-2289 [PubMed]
Cuperus R. Modulation of fenretinide induced cell death in neuroblastoma. S.l.: s.n.; 2014. 162p. ISBN 9789090284538 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): van Kuilenburg ABP, Tytgat GAM)
Hopman SMJ. Cancer predisposition in children: genetics, phenotypes & screening. s.l.: s.n.; 2014. 244p. ISBN 9789090282015 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, Hennekam RCM; copromotor(s): Merks JHM)
Schepers SA, Engelen VE, Haverman L, Caron HN, Hoogerbrugge PM, Kaspers GJL, Egeler RM, Grootenhuis MA, Patient reported outcomes in pediatric oncology practice: suggestions for future usage by parents and pediatric oncologists. PEDIATR BLOOD CANCER 2014;61 (9):1707-1710 [PubMed]
van Dalen EC, Raphaël MF, Caron HN, Kremer LCM, Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer. COCHRANE DB SYST REV 2014;2014 (9):CD006647 [PubMed]
van Dijk I. Radiation-associated adverse events after childhood cancer. s.l.: s.n.; 2014. 190p. ISBN 9789090281452 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, Koning CCE; copromotor(s): Kremer LCM)
van Dijk IWEM, van Os RM, van de Kamer JB, Franken NAP, van der Pal HJH, Koning CCE, Caron HN, Ronckers CM, Kremer LCM, The use of equivalent radiation dose in the evaluation of late effects after childhood cancer treatment. J CANCER SURVIV 2014;8 (4):638-646 [PubMed]
Aukema EJ. Care for consequences in children treated for leukemia or brain tumor. s.l.: s.n.; 2013. 160p. ISBN 9789082006216 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Grootenhuis MA, Last BF; copromotor(s): Schouten-van Meeteren AYN, Caron HN)
Bleeker G, Schoot RA, Caron HN, de Kraker J, Hoefnagel CA, van Eck BL, Tytgat GA, Toxicity of upfront ¹³¹I-metaiodobenzylguanidine (¹³¹I-MIBG) therapy in newly diagnosed neuroblastoma patients: a retrospective analysis. EUR J NUCL MED MOL I 2013;40 (11):1711-1717 [PubMed]
Dupuis LLE. Optimization of pediatric haematopoietic stem cell transport outcomes through the application of pharmacokinetics and supportive care. s.l.: s.n.; 2013. 152p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Offringa M, Caron HN; copromotor(s): )
Hartsink-Segers SA, Exalto C, Allen M, Williamson D, Clifford SC, Horstmann M, Caron HN, Pieters R, den Boer ML, Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells. HAEMATOLOGICA 2013;98 (10):1539-1546 [PubMed]
Hartsink-Segers SA, Zwaan CM, Exalto C, Luijendijk MWJ, Calvert VS, Petricoin EF, Evans WE, Reinhardt D, de Haas V , Hedtjärn M, Hansen BR, Koch T, Caron HN, Pieters R, den Boer ML, Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target. LEUKEMIA 2013;27 (3):560-568 [PubMed]
Hopman S, Merks J, Eussen H, Douben H, Snijder S, Hennekam R, de Klein A, Caron H, Structural genome variations in individuals with childhood cancer and tumour predisposition syndromes. EUR J CANCER 2013;49 (9):2170-2178 [PubMed]
Hopman SMJ, Merks JHM, de Borgie CAJM, Aalfs CM, Biesecker LG, Cole T, Eng C, Legius E, Maher ER, van Noesel MM, Verloes A, Viskochil DH, Wagner A, Weksberg R, Caron HN, Hennekam RCM, The development of a clinical screening instrument for tumour predisposition syndromes in childhood cancer patients. EUR J CANCER 2013;49 (15):3247-3254 [PubMed]
Knijnenburg SL. Late effects of childhood cancer. Epidemiology and patient education. s.l.: s.n.; 2013. 296p. ISBN 9789090275659 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Jaspers MWM, Caron HN; copromotor(s): Kremer LCM)
Knijnenburg SL, Kremer LC, Versluys AB, Braam KI, Mud MS, van der Pal HJ, Caron HN, Jaspers MW, Evaluation of a patient information website for childhood cancer survivors. SUPPORT CARE CANCER 2013;21 (4):919-926 [PubMed]
Knijnenburg SL, Raemaekers S, van den Berg H, van Dijk IWEM , Lieverst JA, van der Pal HJ, Jaspers MWM, Caron HN, Kremer LC, van Santen HM, Final height in survivors of childhood cancer compared with Height Standard Deviation Scores at diagnosis. ANN ONCOL 2013;24 (4):1119-1126 [PubMed]
Knops RRG, van Dalen EC, Mulder RL, Leclercq E, Knijnenburg SL, Kaspers GJL, Pieters R, Caron HN, Kremer LCM, The volume effect in paediatric oncology: a systematic review. ANN ONCOL 2013;24 (7):1749-1753 [PubMed]
Kremer LCM, Mulder RL, Oeffinger KC, Bhatia S, Landier W, Levitt G, Constine LS, Wallace WH, Caron HN, Armenian SH, Skinner R, Hudson MM, A Worldwide Collaboration to Harmonize Guidelines for the Long-Term Follow-Up of Childhood and Young Adult Cancer Survivors: A Report From the International Late Effects of Childhood Cancer Guideline Harmonization Group. PEDIATR BLOOD CANCER 2013;60 (4):543-549 [PubMed]
Maurice-Stam H, Verhoof EJ, Caron HN, Grootenhuis MA, Are survivors of childhood cancer with an unfavourable psychosocial developmental trajectory more likely to apply for disability benefits?. PSYCHO-ONCOLOGY 2013;22 (3):708-714 [PubMed]
Mulder RL. Optimization of care for survivors of childhood cancer. s.l.: s.n.; 2013. 268p. ISBN 9789461084026 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Kremer LCM, van Dalen EC)
Mulder RL, Knijnenburg SL, Geskus RB, van Dalen EC, van der Pal HJH, Koning CCE, Bouts AH, Caron HN, Kremer LCM, Glomerular function time trends in long-term survivors of childhood cancer: a longitudinal study. CANCER EPIDEM BIOMAR 2013;22 (10):1736-1746 [PubMed]
Mulder RL, Kremer LCM, Koot BGP, Benninga MA, Knijnenburg SL, van der Pal HJH, Koning CCE, Oldenburger F, Wilde JCH, Taminiau JAJM, Caron HN, van Dalen EC, Surveillance of hepatic late adverse effects in a large cohort of long-term survivors of childhood cancer: prevalence and risk factors. EUR J CANCER 2013;49 (1):185-193 [PubMed]
Schoot RA, Bleeker G, Caron HN, van Eck BL, Heij HA, de Kraker J, Tytgat GA, The role of 131I-metaiodobenzylguanidine (MIBG) therapy in unresectable and compromising localised neuroblastoma. EUR J NUCL MED MOL I 2013;40 (10):1516-1522 [PubMed]
Schoot RA, McHugh K, van Rijn RR, Kremer LCM, Chisholm JC, Caron HN, Merks JHM, Response assessment in pediatric rhabdomyosarcoma: can response evaluation criteria in solid tumors replace three-dimensional volume assessments?. RADIOLOGY 2013;269 (3):870-878 [PubMed]
Sieswerda E. Childhood cancer survivors: evidence & care. s.l.: s.n.; 2013. 271p. ISBN 9789461694027 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Kremer LCM)
Sieswerda E, Mulder RL, van Dijk IWEM , van Dalen EC, Knijnenburg SL, van der Pal HJH, Mud MS, Heinen RC, Caron HN, Kremer LCM, The EKZ/AMC childhood cancer survivor cohort: methodology, clinical characteristics, and data availability. J CANCER SURVIV 2013;7 (3):439-454 [PubMed]
van Dijk IWEM, Cardous-Ubbink MC, van der Pal HJH, Heinen RC, van Leeuwen FE, Oldenburger F, van Os RM, Ronckers CM, Schouten-van Meeteren AYN, Caron HN, Koning CCE, Kremer LCM, Dose-effect relationships for adverse events after cranial radiation therapy in long-term childhood cancer survivors. INT J RADIAT ONCOL 2013;85 (3):768-775 [PubMed]
Visscher H, Ross CJD, Rassekh SR, Sandor GSS, Caron HN, van Dalen EC, Kremer LC, van der Pal HJ, Rogers PC, Rieder MJ, Carleton BC, Hayden MR [Contributors: Hayden M, Carleton B, Ross C, MacLeod S, Wasserman W, Mitton C, Smith A, Hildebrand C, Pastrana LC, Ghannadan R, Rassekh R, Lim J, Carter C, Miao F, Visscher H, Pussegoda K, Higginson M, Butland S, Yazdanpanah M, Nijssen-Jordan C, Johnson D, Verbeek L, Kaczowka R, Stevenson P, Grundy P, Stobart K, Wilson B, Desai S, Spavor M, Churcher L, Chow T, Hall K, Honcharik N, Israels S, Chan S, Garnham B, Staub M, Rieder M, Malkin B, Portwine C, Cranston A, Koren G, Ito S, Nathan P, Greenberg M, Bournissen FG, Inoue M, Sakaguchi S, Tanaka T, Fujii H, Ogawa M, Ingram R, Kamiya T, Karande S, Silva M, Willing S, Vaillancourt R, Elliott-Miller P, Johnston D, Mankoo H, Wong E, Wilson B, O'Connor L, Maher M, Bussières JF, Lebel D, Barret P, Closon A, Dubé MP, Phillips M, Jabado N, Santo AE, Nagy M, Avard D, Murray M, Boliver D, Tiller M]] , Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children. PEDIATR BLOOD CANCER 2013;60 (8):1375-1381 [PubMed]
Yalcin B, Kremer LC, Caron HN, van Dalen EC, High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma. COCHRANE DB SYST REV 2013;2013 (8):CD006301 [PubMed]
Besançon OG, Tytgat GAM, Meinsma R, Leen R, Hoebink J, Kalayda GV, Jaehde U, Caron HN, van Kuilenburg ABP, Synergistic interaction between cisplatin and gemcitabine in neuroblastoma cell lines and multicellular tumor spheroids. CANCER LETT 2012;319 (1):23-30 [PubMed]
de Lijster MS, Bergevoet RM, van Dalen EC, Michiels EMC, Caron HN, Kremer LCM, Aronson DC, Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children. COCHRANE DB SYST REV 2012;2012 (1):CD008403 [PubMed]
Engelen V , Detmar S, Koopman H, Maurice-Stam H, Caron H, Hoogerbrugge P, Egeler RM, Kaspers G, Grootenhuis M, Reporting health-related quality of life scores to physicians during routine follow-up visits of pediatric oncology patients: Is it effective?. PEDIATR BLOOD CANCER 2012;58 (5):766-774 [PubMed]
Engelen V , van Zwieten M, Koopman H, Detmar S, Caron H, Brons P, Egeler M, Kaspers GJ, Grootenhuis M, The influence of patient reported outcomes on the discussion of psychosocial issues in children with cancer. PEDIATR BLOOD CANCER 2012;59 (1):161-166 [PubMed]
Israels T, Chagaluka G, Pidini D, Caron H, de Kraker J, Kamiza S, Borgstein E, Molyneux L, The efficacy and toxicity of SIOP preoperative chemotherapy in Malawian children with a Wilms tumour. PEDIATR BLOOD CANCER 2012;59 (4):636-641 [PubMed]
Knijnenburg SL, Jaspers MW, van der Pal HJ, Schouten-van Meeteren AY, Bouts AH, Lieverst JA, Bökenkamp A, Koning CCE, Oldenburger F, Wilde JCH, van Leeuwen FE, Caron HN, Kremer LC, Renal Dysfunction and Elevated Blood Pressure in Long-Term Childhood Cancer Survivors. CLIN J AM SOC NEPHRO 2012;7 (9):1416-1427 [PubMed]
Knops RRG, Hulscher MEJL, Hermens RPMG, Hilbink-Smolders M, Loeffen JL, Kollen WJW, Kaspers GJL, Caron HN, Kremer LCM, High-quality care for all children with cancer. ANN ONCOL 2012;23 (7):1906-1911 [PubMed]
Lamers F, Schild L, den Hartog IJM, Ebus ME, Westerhout EM, Ora I, Koster J, Versteeg R, Caron HN, Molenaar JJ, Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth. EUR J CANCER 2012;48 (16):3093-3103 [PubMed]
Lamers F, Schild L, Koster J, Speleman F, Øra I, Westerhout EM, van Sluis P, Versteeg R, Caron HN, Molenaar JJ, Identification of BIRC6 as a novel intervention target for neuroblastoma therapy. BMC CANCER 2012;12 (1):285 [PubMed]
Lamers F, Schild L, Koster J, Versteeg R, Caron HN, Molenaar JJ, Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression. EUR J CANCER 2012;48 (5):763-771 [PubMed]
Lamers SGM. New therapeutic targets in the intrinsic apoptotic pathway in neuroblastoma. s.l.: s.n.; 2012. 135p. ISBN 9789462030404 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Versteeg R, Caron HN; copromotor(s): Molenaar JJ)
Molenaar JJ, Domingo-Fernández R, Ebus ME, Lindner S, Koster J, Drabek K, Mestdagh P, van Sluis P, Valentijn LJ, van Nes J, Broekmans M, Haneveld F, Volckmann R, Bray I, Heukamp L, Sprüssel A, Thor T, Kieckbusch K, Klein-Hitpass L, Fischer M, Vandesompele J, Schramm A, van Noesel MM, Varesio L, Speleman F, Eggert A, Stallings RL, Caron HN, Versteeg R, Schulte JH, LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression. NAT GENET 2012;44 (11):1199-1206 [PubMed]
Molenaar JJ, Koster J, Ebus ME, van Sluis P, Westerhout EM, de Preter K, Gisselsson D, Øra I, Speleman F, Caron HN, Versteeg R, Copy Number Defects of G1-Cell Cycle Genes in Neuroblastoma are Frequent and Correlate with High Expression of E2F Target Genes and a Poor Prognosis. GENE CHROMOSOME CANC 2012;51 (1):10-19 [PubMed]
Molenaar JJ, Koster J, Zwijnenburg DA, van Sluis P, Valentijn LJ, van der Ploeg I, Hamdi M, van Nes J, Westerman BA, van Arkel J, Ebus ME, Haneveld F, Lakeman A, Schild L, Molenaar P, Stroeken P, van Noesel MM, Ora I, Santo EE, Caron HN, Westerhout EM, Versteeg R, Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. NATURE 2012;483 (7391):589-U107 [PubMed]
Santo EE , Ebus ME, Koster J, Schulte JH, Lakeman A, van Sluis P, Vermeulen J, Gisselsson D, Øra I, Lindner S, Buckley PG, Stallings RL, Vandesompele J, Eggert A, Caron HN, Versteeg R, Molenaar JJ, Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma. ONCOGENE 2012;31 (12):1571-1581 [PubMed]
Schoot RA, van Ommen CH, Caron HN, Tissing WJE, van de Wetering MD, Accrual in supportive care trials in pediatric oncology, a challenge!. SUPPORT CARE CANCER 2012;20 (12):3149-3153 [PubMed]
Sieswerda E, Postma A, van Dalen EC, van der Pal HJH, Tissing WJE, Rammeloo LAJ, Kok WEM, van Leeuwen FE, Caron HN, Kremer LCM, The Dutch Childhood Oncology Group guideline for follow-up of asymptomatic cardiac dysfunction in childhood cancer survivors. ANN ONCOL 2012;23 (8):2191-2198 [PubMed]
Stutterheim J, Ichou FA, den Ouden E, Versteeg R, Caron HN, Tytgat GAM, van der Schoot CE, Methylated RASSF1a Is the First Specific DNA Marker for Minimal Residual Disease Testing in Neuroblastoma. CLIN CANCER RES 2012;18 (3):808-814 [PubMed]
Stutterheim J, Zappeij-Kannegieter L, Ora I, van Sluis PG, Bras J, den Ouden E, Versteeg R, Caron HN, van der Schoot CE, Tytgat GAM, Stability of PCR Targets for Monitoring Minimal Residual Disease in Neuroblastoma. J MOL DIAGN 2012;14 (2):168-175 [PubMed]
van der Pal HJ, van Dalen EC, van Delden E, van Dijk IW, Kok WE, Geskus RB, Sieswerda E, Oldenburger F, Koning CC, van Leeuwen FE, Caron HN, Kremer LC, High Risk of Symptomatic Cardiac Events in Childhood Cancer Survivors. J CLIN ONCOL 2012;30 (13):1429-1437 [PubMed]
van de Wetering MD, D'Angio G, Caron H, Obituary of a Very Special Doctor, Dr Jan de Kraker (October 18, 1944 to January 19, 2012). J PEDIAT HEMATOL ONC 2012;34 (4):245-246 [PubMed]
Visscher H, Ross CJD, Rassekh SR, Barhdadi A, Dubé MP, Al-Saloos H, Sandor GS, Caron HN, van Dalen EC, Kremer LC, van der Pal HJ, Brown AMK, Rogers PC, Phillips MS, Rieder MJ, Carleton BC, Hayden MR [Contributors: Visscher H, Ross CJD, Rassekh SR, Dube MP, Sandor GS, Rogers PC, Phillips MS, Rieder MJ, Carleton BC, Hayden MR, Caron HN, van Dalen EC, Kremer LC, van der Pal HJ, Brown AMK, Al-Saloos H, Barhdadi A]] , Pharmacogenomic Prediction of Anthracycline-Induced Cardiotoxicity in Children. J CLIN ONCOL 2012;30 (13):1422-1428 [PubMed]
Cuperus R, van Kuilenburg ABP, Leen R, Bras J, Caron HN, Tytgat GAM, Promising effects of the 4HPR-BSO combination in neuroblastoma monolayers and spheroids. FREE RADICAL BIO MED 2011;51 (6):1213-1220 [PubMed]
Engelen V. Monitoring quality of life in paediatric oncology practice. s.l.: s.n.; 2011. 173p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Grootenhuis MA, Detmar SB, Koopman HM)
Frakking FNJ, Brouwer N, Dolman KM, van Woensel JBM, Caron HN, Kuijpers TW, van de Wetering MD, Mannose-binding lectin (MBL) as prognostic factor in paediatric oncology patients. CLIN EXP IMMUNOL 2011;165 (1):51-59 [PubMed]
Frakking FNJ, Israëls J, Kremer LCM, Kuijpers TW, Caron HN, van de Wetering MD, Mannose-Binding Lectin (MBL) and the Risk for Febrile Neutropenia and Infection in Pediatric Oncology Patients With Chemotherapy. PEDIATR BLOOD CANCER 2011;57 (1):89-96 [PubMed]
Lamers F, van der Ploeg I, Schild L, Ebus ME, Koster J, Hansen BR, Koch T, Versteeg R, Caron HN, Molenaar JJ, Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe. ENDOCR-RELAT CANCER 2011;18 (6):657-668 [PubMed]
Mulder RL, Thönissen NM, van der Pal HJH, Bresser P, Hanselaar W, Koning CCE, Oldenburger F, Heij HA, Caron HN, Kremer LCM, Pulmonary function impairment measured by pulmonary function tests in long-term survivors of childhood cancer. THORAX 2011;66 (12):1065-1071 [PubMed]
Mulder RL, van Dalen EC, van den Hof M, Bresters D, Koot BGP, Castellino SM, Loke Y, Leclercq E, Post PN, Caron HN, Postma A, Kremer LCM, Hepatic late adverse effects after antineoplastic treatment for childhood cancer. COCHRANE DB SYST REV 2011;2011 (7):CD008205 [PubMed]
Sieswerda E, Kremer LCM, Caron HN, van Dalen EC, The use of liposomal anthracycline analogues for childhood malignancies: A systematic review. EUR J CANCER 2011;47 (13):2000-2008 [PubMed]
Sieswerda E, van Dalen EC, Postma A, Cheuk DK, Caron HN, Kremer LCM, Medical interventions for treating anthracycline-induced symptomatic and asymptomatic cardiotoxicity during and after treatment for childhood cancer. COCHRANE DB SYST REV 2011;2011 (9):CD008011 [PubMed]
Stutterheim J. Minimal residual disease detection and monitoring in children with neuroblastoma. s.l.: s.n.; 2011. 221p. ISBN 9789490371869 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, van der Schoot CE; copromotor(s): Tytgat GAM)
Stutterheim J, Zappeij-Kannegieter L, Versteeg R, Caron HN, van der Schoot CE, Tytgat GAM, The prognostic value of fast molecular response of marrow disease in patients aged over 1 year with stage 4 neuroblastoma. EUR J CANCER 2011;47 (8):1193-1202 [PubMed]
Tromp K, Claessens JJM, Knijnenburg SL, van der Pal HJH, van Leeuwen FE, Caron HN, Beerendonk CCM, Kremer LCM, Reproductive status in adult male long-term survivors of childhood cancer. HUM REPROD 2011;26 (7):1775-1783 [PubMed]
van Dalen EC, Caron HN, Dickinson HO, Kremer LCM, Cardioprotective interventions for cancer patients receiving anthracyclines. COCHRANE DB SYST REV 2011;2011 (6):CD003917 [PubMed]
van Dalen EC, Raphael MF, Caron HN, Kremer LC, Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer. COCHRANE DB SYST REV 2011;2011 (1):CD006647 [PubMed]
van Dalen EC, van den Berg H, Raphaël MF, Caron HN, Kremer LC, Should anthracyclines and dexrazoxane be used for children with cancer?. LANCET ONCOL 2011;12 (1):12-13 [PubMed]
van der Pal HJH. Cardiovascular disease after treatment for childhood cancer. s.l.: s.n.; 2011. 246p. ISBN 9789461901040 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, van Leeuwen FE; copromotor(s): Kremer LCM)
van der Pal HJ, van Dalen EC, Hauptmann M, Kok WE, Caron HN, van den Bos C, Oldenburger F, Koning CC, van Leeuwen FE, Kremer LC, Cardiac Function in 5-Year Survivors of Childhood Cancer Reply. ARCH INTERN MED 2011;171 (3):264-265
Bramer JAM. Prognostic factors and late effects of treatment in localised high grade extremity osteosarcoma. s.l.: s.n.; 2010. 165p. ISBN 9789090253763 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Dijk CN, Caron HN; copromotor(s): Schaap A)
Cardous-Ubbink MC, Geenen MM, Schade KJ, Heinen RC, Caron HN, Kremer LCM, van Leeuwen FE, Hypertension in long-term survivors of childhood cancer: A nested case-control study. EUR J CANCER 2010;46 (4):782-790 [PubMed]
Caron HN, Are thoracic neuroblastomas really different?. PEDIATR BLOOD CANCER 2010;54 (7):867 [PubMed]
Cuperus R, Leen R, Tytgat GAM, Caron HN, van Kuilenburg ABP, Fenretinide induces mitochondrial ROS and inhibits the mitochondrial respiratory chain in neuroblastoma. CELL MOL LIFE SCI 2010;67 (5):807-816 [PubMed]
de Brouwer S, de Preter K, Kumps C, Zabrocki P, Porcu M, Westerhout EM, Lakeman A, Vandesompele J, Hoebeeck J, van Maerken T, de Paepe A, Laureys G, Schulte JH, Schramm A, van den Broecke C, Vermeulen J, van Roy N, Beiske K, Renard M, Noguera R, Delattre O, Janoueix-Lerosey I, Kogner P, Martinsson T, Nakagawara A, Ohira M, Caron HN, Eggert A, Cools J, Versteeg R, Speleman F, Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification. CLIN CANCER RES 2010;16 (17):4353-4362 [PubMed]
de Lijster MS, Bergevoet RM, van Dalen EC, Michiels EMC, Caron HN, Kremer LCM, Aronson DC, Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children. COCHRANE DB SYST REV 2010;2010 (3):CD008403 [PubMed]
Fardin P, Barla A, Mosci S, Rosasco L, Verri A, Versteeg R, Caron HN, Molenaar JJ, Ora I, Eva A, Puppo M, Varesio L, A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients. MOL CANCER 2010;9 (1):185 [PubMed]
Geerts D, Koster J, Albert D, Koomoa DLT, Feith DJ, Pegg AE, Volckmann R, Caron H, Versteeg R, Bachmann AS, The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification. INT J CANCER 2010;126 (9):2012-2024 [PubMed]
Hölzel M, Huang S, Koster J, Ora I, Lakeman A, Caron H, Nijkamp W, Xie J, Callens T, Asgharzadeh S, Seeger RC, Messiaen L, Versteeg R, Bernards R, NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome. CELL 2010;142 (2):218-229 [PubMed]
Israëls T. Aspects of the management of children with cancer in Malawi. s.l.: s.n.; 2010. 153p. ISBN 9789081522519 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): de Kraker J, Molyneux EM, Reis R)
Israels T, Damen CWN, Cole M, van Geloven N, Boddy AV, Caron HN, Beijnen JH, Molyneux EM, Veal GJ, Malnourished Malawian patients presenting with large Wilms tumours have a decreased vincristine clearance rate. EUR J CANCER 2010;46 (10):1841-1847 [PubMed]
Molenaar JJ , Ebus ME, Koster J, Santo E, Geerts D, Versteeg R, Caron HN, Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells. ONCOGENE 2010;29 (18):2739-2745 [PubMed]
Park JR, Eggert A, Caron H, Neuroblastoma: biology, prognosis, and treatment. HEMATOL ONCOL CLIN N 2010;24 (1):65-86 [PubMed]
van Dalen EC, Michiels EMC, Caron HN, Kremer LCM, Different anthracycline derivates for reducing cardiotoxicity in cancer patients. COCHRANE DB SYST REV 2010;2010 (5):CD005006 [PubMed]
van Dalen EC, Michiels EMC, Caron HN, Kremer LCM, Different anthracycline derivates for reducing cardiotoxicity in cancer patients. COCHRANE DB SYST REV 2010;2010 (3):CD005006 [PubMed]
van Dalen EC, Mulder RL, Caron HN, Kremer LCM, Response to "Cancer care in the pediatric surgical patient: A paradigm to abolish volume-outcome disparities in surgery". SURGERY 2010;147 (2):310-311 [PubMed]
van der Pal HJ, van Dalen EC, Hauptmann M, Kok WE, Caron HN, van den Bos C, Oldenburger F, Koning CC, van Leeuwen FE, Kremer LC, Cardiac Function in 5-Year Survivors of Childhood Cancer A Long-term Follow-up Study. ARCH INTERN MED 2010;170 (14):1247-1255 [PubMed]
van Dijk IWEM, Oldenburger F, Cardous-Ubbink MC, Geenen MM, Heinen RC, de Kraker J, van Leeuwen FE, van der Pal HJH, Caron HN, Koning CCE, Kremer LCM, EVALUATION OF LATE ADVERSE EVENTS IN LONG-TERM WILMS' TUMOR SURVIVORS. INT J RADIAT ONCOL 2010;78 (2):370-378 [PubMed]
Yalçin B, Kremer LCM, Caron HN, van Dalen EC, High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma. COCHRANE DB SYST REV 2010;2010 (5):CD006301 [PubMed]
Zwaan CM, Kearns P, Caron H, Verschuur A, Riccardi R, Boos J, Doz F, Geoerger B, Morland B, Vassal G, The role of the 'innovative therapies for children with cancer' (ITCC) European consortium. CANCER TREAT REV 2010;36 (4):328-334 [PubMed]
Brouwer N, Frakking FNJ, van de Wetering MD, van Houdt M, Hart M, Budde IK, Strengers PFW, Laursen I, Houen G, Roos D, Jensenius JC, Caron HN, Dolman KM, Kuijpers TW, Mannose-Binding Lectin (MBL) Substitution: Recovery of Opsonic Function In Vivo Lags behind MBL Serum Levels. J IMMUNOL 2009;183 (5):3496-3504 [PubMed]
Damen CWN, Israëls T, Caron HN, Schellens JHM, Rosing H, Beijnen JH, Validated assay for the simultaneous quantification of total vincristine and actinomycin-D concentrations in human EDTA plasma and of vincristine concentrations in human plasma ultrafiltrate by high-performance liquid chromatography coupled with tandem mass spectrometry. RAPID COMMUN MASS SP 2009;23 (6):763-774 [PubMed]
Frakking FNJ, Brouwer N, van de Wetering MD, Budde IK, Strengers PFW, Huitema AD, Laursen I, Houen G, Caron HN, Dolman KM, Kuijpers TW, Safety and pharmacokinetics of plasma-derived mannose-binding lectin (MBL) substitution in children with chemotherapy-induced neutropaenia. EUR J CANCER 2009;45 (4):505-512 [PubMed]
Israëls T, Borgstein E, Jamali M, de Kraker J, Caron HN, Molyneux EM, Acute Malnutrition Is Common in Malawian Patients With a Wilms Tumour: A Role for Peanut Butter. PEDIATR BLOOD CANCER 2009;53 (7):1221-1226 [PubMed]
Israëls T, Molyneux EM, Caron HN, Jamali M, Banda K, Bras H, Kamiza S, Borgstein E, de Kraker J, Preoperative Chemotherapy for Patients With Wilms Tumor in Malawi Is Feasible and Efficacious. PEDIATR BLOOD CANCER 2009;53 (4):584-589 [PubMed]
Israëls T, van de Wetering MD, Hesseling P, van Geloven N, Caron HN, Molyneux EM, Malnutrition and Neutropenia in Children Treated for Burkitt Lymphoma in Malawi. PEDIATR BLOOD CANCER 2009;53 (1):47-52 [PubMed]
Maurice-Stam H, Oort FJ, Last BF, Brons PPT, Caron HN, Grootenhuis MA, School-aged children after the end of successful treatment of non-central nervous system cancer: longitudinal assessment of health-related quality of life, anxiety and coping. EUR J CANCER CARE 2009;18 (4):401-410 [PubMed]
Molenaar JJ. The cell cycle in neuroblastoma. From genomic aberrations to targeted intervention. s.l.: s.n.; 2009. 132p. ISBN 9789090245003 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, Versteeg R; copromotor(s): )
Molenaar JJ, Ebus ME, Geerts D, Koster J, Lamers F, Valentijn LJ, Westerhout EM, Versteeg R, Caron HN, Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells. P NATL ACAD SCI USA 2009;106 (31):12968-12973 [PubMed]
Mulder RL, Kremer LCM, van Santen HM, Ket JL, van Trotsenburg ASP, Koning CCE, Schouten-van Meeteren AYN, Caron HN, Neggers SJCMM, van Dalen EC, Prevalence and risk factors of radiation-induced growth hormone deficiency in childhood cancer survivors: A systematic review. CANCER TREAT REV 2009;35 (7):616-632 [PubMed]
Stutterheim J, Gerritsen A, Zappeij-Kannegieter L, Yalcin B, dee R, van Noesel MM, Berthold F, Versteeg R, Caron HN, van der Schoot CE, Tytgat GAM, Detecting Minimal Residual Disease in Neuroblastoma: The Superiority of a Panel of Real-Time Quantitative PCR Markers. CLIN CHEM 2009;55 (7):1316-1326 [PubMed]
ten Bruggencate MJM, Kremer LCM, Caron HN, Knops AM, van Dalen EC, Pediatric oncologists and evidence-based medicine: A postal survey in The Netherlands. PEDIATR BLOOD CANCER 2009;52 (2):231-236 [PubMed]
Ubbink MC. Long-term excess mortality and morbidity following treatment of childhood cancer. s.l.: s.n.; 2009. 135p. ISBN 9789789090244495 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, van Leeuwen FE; copromotor(s): Bakker PJM, Kremer LCM)
van Dalen EC, Raphaël MF, Caron HN, Kremer LCM, Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer. COCHRANE DB SYST REV 2009;2009 (1):CD006647 [PubMed]
van Dalen EC, van der Pal HJH, Caron HN, Kremer LCM, Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy. COCHRANE DB SYST REV 2009;2009 (4):CD005008 [PubMed]
van Engelen K, Merks JHM, Lam J, Kremer LCM, Backes M, Baars MJH, van der Pal HJH, Postma AV, Versteeg R, Caron HN, Mulder BJM, Prevalence of congenital heart defects in neuroblastoma patients: a cohort study and systematic review of literature. EUR J PEDIATR 2009;168 (9):1081-1090 [PubMed]
Cuperus R, Tytgat GAM, Leen R, Brites P, Bras J, Caron HN, van Kuilenburg ABP, Pleiotropic effects of fenretinide in neuroblastoma cell lines and multicellular tumor spheroids. INT J ONCOL 2008;32 (5):1011-1019 [PubMed]
de Haas T, Hasselt N, Troost D, Caron H, Popovic M, Zadravec-Zaletel L, Grajkowska W, Perek M, Osterheld MC, Ellison D, Baas F, Versteeg R, Kool M, Molecular risk stratification of medulloblastoma patients based on immunohistochemical analysis of MYC, LDHB, and CCNB1 expression. CLIN CANCER RES 2008;14 (13):4154-4160 [PubMed]
de Kraker J, Hoefnagel KA, Verschuur AC, van Eck B, van Santen HM, Caron HN, Iodine-131-metaiodobenzylguanidine as initial induction therapy in stage 4 neuroblastoma patients over 1 year of age. EUR J CANCER 2008;44 (4):551-556 [PubMed]
Israëls T, Chirambo C, Caron H, de Kraker J, Molyneux E, Reis R, The guardians' perspective on paediatric cancer treatment in Malawi and factors affecting adherence. PEDIATR BLOOD CANCER 2008;51 (5):639-642 [PubMed]
Israels T, Chirambo C, Caron HN, Molyneux EM, Nutritional status at admission of children with cancer in Malawi. PEDIATR BLOOD CANCER 2008;51 (5):626-628 [PubMed]
Kool M, Koster J, Bunt J, Hasselt NE, Lakeman A, van Sluis P, Troost D, Schouten-van Meeteren NAY, Caron HN, Cloos J, Mrsić A, Ylstra B, Grajkowska W, Hartmann W, Pietsch T, Ellison D, Clifford SC, Versteeg R, Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features. PLOS ONE 2008;3 (8):e3088 [PubMed]
Koppen A, Ait-Aissa R, Koster J, Øra I, Bras J, van Sluis PG, Caron H, Versteeg R, Valentijn LJ, Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN. INT J CANCER 2008;122 (7):1455-1464 [PubMed]
Maurice-Stam H, Oort FJ, Last BF, Brons PPT, Caron HN, Grootenhuis MA, Longitudinal assessment of health-related quality of life in preschool children with non-CNS cancer after the end of successful treatment. PEDIATR BLOOD CANCER 2008;50 (5):1047-1051 [PubMed]
Merks JHM, Ozgen HM, Koster J, Zwinderman AH, Caron HN, Hennekam RCM, Prevalence and patterns of morphological abnormalities in patients with childhood cancer. JAMA-J AM MED ASSOC 2008;299 (1):61-69 [PubMed]
Molenaar JJ, Ebus ME, Koster J, van Sluis P, van Noesel CJM, Versteeg R, Caron HN, Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma. CANCER RES 2008;68 (8):2599-2609 [PubMed]
Park JR, Eggert A, Caron H, Neuroblastoma: biology, prognosis, and treatment. PEDIATR CLIN N AM 2008;55 (1):97-120, x [PubMed]
Stutterheim J, Gerritsen A, Zappeij-Kannegieter L, Kleijn I, dee R, Hooft L, van Noesel MM, Bierings M, Berthold F, Versteeg R, Caron HN, van der Schoot CE, Tytgat GAM, PHOX2B Is a Novel and Specific Marker for Minimal Residual Disease Testing in Neuroblastoma. J CLIN ONCOL 2008;26 (33):5443-5449 [PubMed]
van Dalen EC, Caron HN, Dickinson HO, Kremer LCM, Cardioprotective interventions for cancer patients receiving anthracyclines. COCHRANE DB SYST REV 2008;2008 (2):CD003917 [PubMed]
Cardous-Ubbink MC, Heinen RC, Bakker PJM, van den Berg H, Oldenburger F, Caron HN, Voûte PA, van Leeuwen FE, Risk of second malignancies in long-term survivors of childhood cancer. EUR J CANCER 2007;43 (2):351-362 [PubMed]
Geenen MM, Cardous-Ubbink MC, Kremer LCM, van den Bos C, van der Pal HJH, Heinen RC, Jaspers MWM, Koning CCE, Oldenburger F, Langeveld NE, Hart AAM, Bakker PJM, Caron HN, van Leeuwen FE, Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. JAMA-J AM MED ASSOC 2007;297 (24):2705-2715 [PubMed]
Jaspers MWM, van den Bos C, Heinen RC, Bakker PJM, Geenen MM, Kremer LC, van Leeuwen F, Caron HN, Development of a national protocol to screen Dutch cancer survivors on late cancer treatment effects. INT J MED INFORM 2007;76 (4):297-305 [PubMed]
Koppen A, Ait-Aissa R, Koster J, van Sluis PG, Ora I, Caron HN, Volckmann R, Versteeg R, Valentijn LJ, Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma. EUR J CANCER 2007;43 (16):2413-2422 [PubMed]
Kremer LCM, Cardous-Ubbink MC, Geenen MM, van Leeuwen FE, Caron HN, Health outcomes in long-term survivors of childhood cancer - Reply. JAMA-J AM MED ASSOC 2007;298 (14):1635-1636
Maurice-Stam H, Grootenhuis MA, Brons PPT, Caron HN, Last BF, Psychosocial indicators of health-related quality of life in children with cancer 2 months after end of successful treatment. J PEDIAT HEMATOL ONC 2007;29 (8):540-550 [PubMed]
Maurice-Stam H, Grootenhuis MA, Caron HN, Last BF, Course of life of survivors of childhood cancer is related to quality of life in young adulthood. J PSYCHOSOC ONCOL 2007;25 (3):43-58 [PubMed]
Stam H. Surviving childhood cancer. Quality of life, course of life, and coping. s.l.: s.n.; 2007. 321p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Last BF, Caron HN; copromotor(s): Grootenhuis MA)
van Dalen EC. Anthracycline-induced cardiotoxicity during and after treatment for childhood cancer. Long-term risk, risk factors and prevention. s.l.: s.n.; 2007. 262p. ISBN 9789090214047 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Kremer LCM)
van Dalen EC, Caron HN, Kremer LCM, Prevention of anthracycline-induced cardiotoxicity in children: the evidence. EUR J CANCER 2007;43 (7):1134-1140 [PubMed]
van den Berg H, Caron HN, Paratesticular neuroblastoma: a case against metastatic disease?. J PEDIAT HEMATOL ONC 2007;29 (3):187-189 [PubMed]
van de Wetering MD, Weggelaar N, Offringa M, Caron HN, Kuijpers TW, Granulocyte transfusions in neutropaenic children: a systematic review of the literature. EUR J CANCER 2007;43 (14):2082-2092 [PubMed]
Bierau J, van Gennip AH, Leen R, Meinsma R, Caron HN, van Kuilenburg ABP, Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma. CANCER CHEMOTH PHARM 2006;57 (1):105-113 [PubMed]
Blokker RS, Smit LME, van den Bos C, Overberg PC, Caron HN, Kaspers GJL, Een jongen met acute cerebellaire ataxie zonder opsoclonus, door een neuroblastoom. NED TIJDSCHR GENEESKD 2006;150 (14):799-803 [PubMed]
de Ruijter AJM, Leen R, Hoebink J, Caron HN, van Kuilenburg ABP, Antagonistic effects of sequential administration of BL1521, a histone deacetylase inhibitor, and gemcitabine to neuroblastoma cells. CANCER LETT 2006;233 (2):240-246 [PubMed]
Frakking FNJ, van de Wetering MD, Brouwer N, Dolman KM, Geissler J, Lemkes B, Caron HN, Kuijpers TW, The role of mannose-binding lectin (MBL) in paediatric oncology patients with febrile neutropenia. EUR J CANCER 2006;42 (7):909-916 [PubMed]
Opocher E, Kremer LCM, Da Dalt L, van de Wetering MD, Viscardi E, Caron HN, Perilongo G, Prognostic factors for progression of childhood optic pathway glioma: a systematic review. EUR J CANCER 2006;42 (12):1807-1816 [PubMed]
Stam H, Grootenhuis MA, Brons PPT, Caron HN, Last BF, Health-related quality of life in children and emotional reactions of parents following completion of cancer treatment. PEDIATR BLOOD CANCER 2006;47 (3):312-319 [PubMed]
Stam H, Grootenhuis MA, Caron HN, Last BF, Quality of life and current coping in young adult survivors of childhood cancer: positive expectations about the further course of the disease were correlated with better quality of life. PSYCHO-ONCOLOGY 2006;15 (1):31-43 [PubMed]
van Dalen EC, Michiels EMC, Caron HN, Kremer LCM, Different anthracycline derivates for reducing cardiotoxicity in cancer patients. COCHRANE DB SYST REV 2006;2006 (4):CD005006 [PubMed]
van Dalen EC, van den Brug M, Caron HN, Kremer LCM, Anthracycline-induced cardiotoxicity: comparison of recommendations for monitoring cardiac function during therapy in paediatric oncology trials. EUR J CANCER 2006;42 (18):3199-3205 [PubMed]
van Dalen EC, van der Pal HJH, Caron HN, Kremer LCM, Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy. COCHRANE DB SYST REV 2006;2006 (4):CD005008 [PubMed]
van Dalen EC, van der Pal HJH, Kok WEM, Caron HN, Kremer LCM, Clinical heart failure in a cohort of children treated with anthracyclines: a long-term follow-up study. EUR J CANCER 2006;42 (18):3191-3198 [PubMed]
van Dalen EC, van der Pal HJH, van den Bos C, Kok WEM, Caron HN, Kremer LCM, Clinical heart failure during pregnancy and delivery in a cohort of female childhood cancer survivors treated with anthracyclines. EUR J CANCER 2006;42 (15):2549-2553 [PubMed]
Buwalda J, Freling NJ, Blank LECM, Balm AJM, Bras J, Voûte PA, Caron HN, Schouwenburg PF, Merks JHM, Amore protocol in pediatric head and neck rhabdomyosarcoma: Descriptive analysis of failure patterns. HEAD NECK-J SCI SPEC 2005;27 (5):390-396 [PubMed]
de Ruijter AJM. Characterization of the effects of a novel histone deacetylase inhibitor, BL1521, on neuroblastoma cells. S.l.: s.n.; 2005. 136p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): van Kuilenburg ABP)
de Ruijter AJM, Meinsma RJ, Bosma P, Kemp S, Caron HN, van Kuilenburg ABP, Gene expression profiling in response to the histone deacetylase inhibitor BL1521 in neuroblastoma. EXP CELL RES 2005;309 (2):451-467 [PubMed]
Houtzager BA, Grootenhuis MA, Caron HN, Last BF, Sibling self-report, parental proxies, and quality of life: the importance of multiple informants for siblings of a critically ill child. PEDIATR HEMAT ONCOL 2005;22 (1):25-40 [PubMed]
Merks JHM, Caron HN, Hennekam RCM, High incidence of malformation syndromes in a series of 1,073 children with cancer. AM J MED GENET A 2005;134A (2):132-143 [PubMed]
Merks JHM, Smets AM, van Rijn RR, Kobes J, Caron HN, Maas M, Hennekam RCM, Prevalence of RIB anomalies in normal Caucasian children and childhood cancer patients. EUR J MED GENET 2005;48 (2):113-129 [PubMed]
Ouwehand K, de Ruijter AJM, van Bree C, Caron HN, van Kuilenburg ABP, Histone deacetylase inhibitor BL1521 induces a G1-phase arrest in neuroblastoma cells through altered expression of cell cycle proteins. FEBS LETT 2005;579 (6):1523-1528 [PubMed]
van Dalen EC, Caron HN, Dickinson HO, Kremer LCM, Cardioprotective interventions for cancer patients receiving anthracyclines. COCHRANE DB SYST REV 2005;2005 (1):CD003917.pub2 [PubMed]
van Dalen EC, van der Pal HJH, Reitsma JB, de Winter RJ, Helbing WA, Ottenkamp J, Caron HN, Kremer LCM, Management of asymptomatic anthracycline-induced cardiac damage after treatment for childhood cancer - A postal survey among dutch adult and pediatric cardiologists. J PEDIAT HEMATOL ONC 2005;27 (6):319-322 [PubMed]
van de Wetering MD, de Witte MA, Kremer LCM, Offringa M, Scholten RJPM, Caron HN, Efficacy of oral prophylactic antibiotics in neutropenic afebrile oncology patients: A systematic review of randomised controlled trials. EUR J CANCER 2005;41 (10):1372-1382 [PubMed]
van de Wetering MD, van Woensel JBM, Kremer LCM, Caron HN, Prophylactic antibiotics for preventing early Gram-positive central venous catheter infections in oncology patients, a Cochrane systematic review. CANCER TREAT REV 2005;31 (3):186-196 [PubMed]
Voûte PA, Barrett A, Stevens M, Caron H, editors, Cancer in children-clinical management. 5th edition. Oxford: Oxford University Press; 2005. -p.
Voûte PA, Barrett A, Stevens MCG, Caron HN, editors, Cancer in children: clinical management (fifth edition). Oxford: Oxford University Press; 2005. -p. ISBN 0-19-852932-5
Bierau J, Leen R, van Gennip AH, Caron HN, van Kuilenburg ABP, Determination of the deoxycytidine kinase activity in cell homogenates with a non-radiochemical assay using reversed-phase high performance liquid chromatography; Identification of a novel metabolite of 2-chlorodeoxyadenosine. J CHROMATOGR B 2004;805 (2):339-346 [PubMed]
Bierau J, van Gennip AH, Leen R, Zoetekouw L, Caron HN, van Kuilenburg ABP, Cyclopentenyl cytosine sensitises SK-N-BE(2)c neuroblastoma cells to cladribine. NED TIJDSCHR KLIN CHEM LABORATORIUMGENEESKD 2004;29:271-272
Buwalda J. AMORE (Ablative surgery, MOulage technique brachytherapy and REconstruction) for childhood head and neck rhabdomyosarcoma. S.l.: s.n.; 2004. 181p. ISBN 90-9018431-9 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, Schouwenburg PF; copromotor(s): )
Buwalda J, Blank LECM, Schouwenburg PF, Copper MP, Strackee SD, Voûte PA, Merks JHM, Caron HN, The AMORE protocol as salvage treatment for non-orbital head and neck rhabdomyosarcoma in children. EJSO-EUR J SURG ONC 2004;30 (8):884-892 [PubMed]
Cardous-Ubbink MC, Heinen RC, Langeveld NE, Bakker PJM, Voûte PA, Caron HN, van Leeuwen FE, Long-term cause-specific mortality among five-year survivors of childhood cancer. PEDIATR BLOOD CANCER 2004;42 (7):563-573 [PubMed]
de Ruijter AJM, Kemp S, Kramer G, Meinsma RJ, Kaufmann JO, Caron HN, van Kuilenburg ABP, The novel histone deacetylase inhibitor BL1521 inhibits proliferation and induces apoptosis in neuroblastoma cells. BIOCHEM PHARMACOL 2004;68 (7):1279-1288 [PubMed]
Houtzager BA. Slibings of pediatric cancer patients. Coping, risk factors and psychological health. S.l.: s.n.; 2004. 231p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Last BF, Grootenhuis MA)
Houtzager BA, Grootenhuis MA, Caron HN, Last BF, Quality of life and psychological adaptation in siblings of paediatric cancer patients, 2 years after diagnosis. PSYCHO-ONCOLOGY 2004;13 (8):499-511 [PubMed]
Houtzager BA , Oort FJ, Hoekstra-Weebers JEHM, Caron HN, Grootenhuis MA, Last BF, Coping and family functioning predict longitudinal psychological adaptation of siblings of childhood cancer patients. J PEDIATR PSYCHOL 2004;29 (8):591-605 [PubMed]
Kremer LCM, Caron HN, Anthracycline cardiotoxicity in children. NEW ENGL J MED 2004;351 (2):120-121 [PubMed]
Merks JH, Ceelie N, Caron HN, Hennekam RC, Neuroblastoma, maternal valproic acid use, in-vitro fertilization and family history of mosaic chromosome 22: coincidence or causal relationship?. CLIN DYSMORPHOL 2004;13 (3):197-198 [PubMed]
Merks JHM. Phenotypic abnormalities in childhood cancer patients; clues for molecular defects?. S.l.: s.n.; 2004. 208p. ISBN 90-9018757-X [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN, Hennekam RCM; copromotor(s): )
van Dalen EC, van der Pal HJH, Bakker PJM, Caron HN, Kremer LCM, Cumulative incidence and risk factors of mitoxantrone-induced cardiotoxicity in children: a systematic review. EUR J CANCER 2004;40 (5):643-652 [PubMed]
van de Wetering MD. Prediction and prevention of infectious complications in children with cancer. S.l.: s.n.; 2004. 201p. ISBN 90-9017972-0 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Kuijpers TW)
van de Wetering MD, Caron HN, Biezeveld M, Taminiau JAJM, ten Kate FJ, Spanjaard L, Kuijpers TW, Severity of enterocolitis is predicted by IL-8 in paediatric oncology patients. EUR J CANCER 2004;40 (4):571-578 [PubMed]
van Limpt V, Schramm A, van Lakeman A, Sluis P, Chan A, van Noesel M, Baas F, Caron H, Eggert A, Versteeg R, The Phox2B homeobox gene is mutated in sporadic neuroblastomas. ONCOGENE 2004;23 (57):9280-9288 [PubMed]
Ambros IM, Benard J, Boavida M, Bown N, Caron H, Combaret V, Couturier J, Darnfors C, Delattre O, Freeman-Edward J, Gambini C, Gross N, Hattinger CM, Luegmayr A, Lunec J, Martinsson T, Mazzocco K, Navarro S, Noguera R, O'Neill S, Potschger U, Rumpler S, Speleman F, Tonini GP, Valent A, van Roy N, Amann G, de Bernardi B, Kogner P, Ladenstein R, Michon J, Pearson ADJ, Ambros PF, Quality assessment of genetic markers used for therapy stratification. J CLIN ONCOL 2003;21 (11):2077-2084 [PubMed]
Bierau J. The pivotal role of CTP synthetase in the metabolism of (deoxy)nucleosides in neuroblastoma. S.l.: s.n.; 2003. 136p. ISBN 90 6464 619 8 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): van Kuilenburg ABP, van Gennip AH)
Bierau J, van Gennip AH, Leen R, Helleman J, Caron HN, van Kuilenburg ABP, Cyclopentenyl cytosine primes SK-N-BE(2)c neuroblastoma cells for cytarabine toxicity. INT J CANCER 2003;103 (3):387-392 [PubMed]
Buwalda J, Schouwenburg PF, Blank LECM, Merks JHM, Copper MP, Strackee SD, Voûte PA, Caron HN, A novel local treatment strategy for advanced stage head and neck rhabdomyosarcomas in children: results of the AMORE protocol. EUR J CANCER 2003;39 (11):1594-1602 [PubMed]
Carlin S, Mairs RJ, McCluskey AG, Tweddle DA, Sprigg A, Estlin C, Board J, George RE, Ellershaw C, Pearson ADJ, Lunec J, Montaldo PG, Ponzoni M, van Eck-Smit BL, Hoefnagel CA, van den Brug MD, Tytgat GAM, Caron HN, Development of a real-time polymerase chain reaction assay for prediction of the uptake of meta-[(131)I]iodobenzylguanidine by neuroblastoma tumors. CLIN CANCER RES 2003;9 (9):3338-3344 [PubMed]
de Ruijter AJM, van Gennip AH, Caron HN, Kemp S, van Kuilenburg ABP, Histone deacetylases (HDACs): characterization of the classical HDAC family. BIOCHEM J 2003;370 (Part 3):737-749 [PubMed]
Godfried MB. Role of nm23 in neuroblastoma. From genetic aberrations to pathways abnormalities. S.l.: s.n.; 2003. 114p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Caron HN; copromotor(s): Versteeg R)
Houtzager BA, Grootenhuis MA, Hoekstra-Weebers JEHM, Caron HN, Last BF, Psychosocial functioning in siblings of paediatric cancer patients one to six months after diagnosis. EUR J CANCER 2003;39 (10):1423-1432 [PubMed]
Merks JHM, van Karnebeek CDM, Caron HN, Hennekam RCM, Phenotypic abnormalities: Terminology and classification. AM J MED GENET A 2003;123A (3):211-230 [PubMed]
Molenaar JJ, van Sluis P, Boon K, Versteeg R, Caron HN, Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma. GENE CHROMOSOME CANC 2003;36 (3):242-249 [PubMed]
van Dalen EC, van der Pal HJH, van den Bos C, Caron HN, Kremer LCM, Treatment for asymptomatic anthracycline-induced cardiac dysfunction in childhood cancer survivors: The need for evidence. J CLIN ONCOL 2003;21 (17):3377-3377; author reply 3378 [PubMed]
van de Wetering MD, Kuijpers TW, Taminiau JAJM, ten Kate FJW, Caron HN, Pseudomembranous and neutropenic enterocolitis in pediatric oncology patients. SUPPORT CARE CANCER 2003;11 (9):581-586 [PubMed]
van Kampen AHC, Ruijter JM, van Schaik BDC, Caron HN, Versteeg R. Gene expression informatics and analysis in: Barnes MR, Gray IC, editors. Bioinformatics for geneticists. Chichester: John Wiley & Sons; 2003., p. 319-344
van Limpt VAE, Chan AJ, van Sluis PG, Caron HN, van Noesel CJM, Versteeg R, High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type. INT J CANCER 2003;105 (1):61-69 [PubMed]
Versteeg R, van Schaik BDC, van Batenburg MF, Roos M, Monajemi R, Caron H, Bussemaker HJ, van Kampen AHC, The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes. GENOME RES 2003;13 (9):1998-2004 [PubMed]
Bierau J, van Gennip AH, Leen R, Caron HN, van Kuilenburg ABP, Retinoic acid reduces the cytotoxicity of cyclopentenyl cytosine in neuroblastoma cells. FEBS LETT 2002;527 (1-3):229-233 [PubMed]
Godfried MB, Veenstra M, Valent A, Sluis Pv, Voûte PA, Versteeg R, Caron HN, Lack of interstitial chromosome 1p deletions in clinically-detected neuroblastoma. EUR J CANCER 2002;38 (11):1513-1519 [PubMed]
Godfried MB, Veenstra M, van Sluis P, Boon K, van Asperen R, Hermus MC, van Schaik BDC, Voûte TPA, Schwab M, Versteeg R, Caron HN, The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2. ONCOGENE 2002;21 (13):2097-2101 [PubMed]
Boon K, Caron HN, van Asperen R, Valentijn L, Hermus MC, van Sluis P, Roobeek I, Weis I, Voûte PA, Schwab M, Versteeg R, N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J 2001;20 (6):1383-1393 [PubMed]
Caron H, Spieker N, Godfried M, Veenstra M, van Sluis P, de Kraker J, Voûte P, Versteeg R, Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted. GENE CHROMOSOME CANC 2001;30 (2):168-174 [PubMed]
Caron H, van Schaik B, van der Mee M, Baas F, Riggins G, van Sluis P, Hermus MC, van Asperen R, Boon K, Voûte PA, Heisterkamp S, van Kampen A, Versteeg R, The human transcriptome map: clustering of highly expressed genes in chromosomal domains. SCIENCE 2001;291 (5507):1289-1292 [PubMed]
Plantaz D, Vandesompele J, van Roy N, Lastowska M, Bown N, Combaret V, Favrot MC, Delattre O, Michon J, Bénard J, Hartmann O, Nicholson JC, Ross FM, Brinkschmidt C, Laureys G, Caron H, Matthay KK, Feuerstein BG, Speleman F, Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lacking MYCN amplification. INT J CANCER 2001;91 (5):680-686 [PubMed]
Spieker N, Beitsma M, van Sluis P, Chan A, Caron H, Versteeg R, Three chromosomal rearrangements in neuroblastoma cluster within a 300-kb region on 1p36.1. GENE CHROMOSOME CANC 2001;31 (2):172-181 [PubMed]
Spieker N, van Sluis P, Beitsma M, Boon K, van Schaik BD, van Kampen AH, Caron H, Versteeg R, The MEIS1 oncogene is highly expressed in neuroblastoma and amplified in cell line IMR32. GENOMICS 2001;71 (2):214-221 [PubMed]
van de Wetering MD, Poole J, Friedland I, Caron HN, Bacteraemia in a paediatric oncology unit in South Africa. MED PEDIATR ONCOL 2001;37 (6):525-531 [PubMed]
Spieker N, Beitsma M, van Sluis P, Roobeek I, den Dunnen JT, Speleman F, Caron H, Versteeg R, An integrated 5-Mb physical, genetic, and radiation hybrid map of a 1p36.1 region implicated in neuroblastoma pathogenesis. GENE CHROMOSOME CANC 2000;27 (2):143-152 [PubMed]
van Kampen AH, van Schaik BD, Pauws E, Michiels EM, Ruijter JM, Caron HN, Versteeg R, Heisterkamp SH, Leunissen JA, Baas F, van der Mee M, USAGE: a web-based approach towards the analysis of SAGE data. Serial Analysis of Gene Expression. BIOINFORMATICS 2000;16 (10):899-905 [PubMed]
van Limpt V, Chan A, Caron H, Sluis PV, Boon K, Hermus MC, Versteeg R, SAGE analysis of neuroblastoma reveals a high expression of the human homologue of the Drosophila Delta gene. MED PEDIATR ONCOL 2000;35 (6):554-558 [PubMed]
Hartwig NG, Caron HN, den Hollander JC, Robben SG, Egeler RM, Neuroblastoma 4S with an unfavorable biological marker: what to do?. MED PEDIATR ONCOL 1999;32 (4):294-300; discussion 301 [PubMed]
van den Berg H, Caron HN, Theunissen PH, Theunissen PM, van der Schoot CE, Kroes W, Beverloo HB, Slater R, Bidirectional differentiation involving a cell with rearrangement of the MLL gene. LEUKEMIA 1998;12 (1):102-103 [PubMed]
Caron HN, Voute PA, Versteeg R, Allelic loss of chromosome 1p in neuroblastoma - Reply. NEW ENGL J MED 1996;334 (24):1609
Caron H, van Sluis P, Buschman R, Pereira do Tanque R, Maes P, Beks L, de Kraker J, Voûte PA, Vergnaud G, Westerveld A, Slater R, Versteeg R, Allelic loss of the short arm of chromosome 4 in neuroblastoma suggests a novel tumour suppressor gene locus. HUM GENET 1996;97 (6):834-837 [PubMed]
Caron H, van Sluis P, de Kraker J, Bökkerink J, Egeler M, Laureys G, Slater R, Westerveld A, Voûte PA, Versteeg R, Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma. NEW ENGL J MED 1996;334 (4):225-230 [PubMed]
Hofstra RM, Cheng NC, Hansen C, Stulp RP, Stelwagen T, Clausen N, Tommerup N, Caron H, Westerveld A, Versteeg R, Buys CH, No mutations found by RET mutation scanning in sporadic and hereditary neuroblastoma. HUM GENET 1996;97 (3):362-364 [PubMed]
Caron H, Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma. MED PEDIATR ONCOL 1995;24 (4):215-221 [PubMed]
Caron H, Peter M, van Sluis P, Speleman F, de Kraker J, Laureys G, Michon J, Brugières L, Voûte PA, Westerveld A, Slater R, Delattre O, Versteeg R, EVIDENCE FOR 2 TUMOR-SUPPRESSOR LOCI ON CHROMOSOMAL BANDS-1P35-36 INVOLVED IN NEUROBLASTOMA - ONE PROBABLY IMPRINTED, ANOTHER ASSOCIATED WITH N-MYC AMPLIFICATION. HUM MOL GENET 1995;4 (4):535-539 [PubMed]
de Kraker J, Hoefnagel CA, Caron H, Valdés Olmos RA, Zsiros J , Heij HA, Voûte PA, First line targeted radiotherapy, a new concept in the treatment of advanced stage neuroblastoma. EUR J CANCER 1995;31A (4):600-602 [PubMed]
Versteeg R, Caron H, Cheng NC, van der Drift P, Slater R, Westerveld A, Voûte PA, Delattre O, Laureys G, van Roy N, 1p36: every subband a suppressor?. EUR J CANCER 1995;31A (4):538-541 [PubMed]
Caron H, van Sluis P, van Roy N, de Kraker J, Speleman F, Voûte PA, Westerveld A, Slater R, Versteeg R, Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity. AM J HUM GENET 1994;55 (2):341-347 [PubMed]
Caron H, van Sluis P, van Hoeve M, de Kraker J, Bras J, Slater R, Mannens M, Voûte PA, Westerveld A, Versteeg R, Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification [Correction]. NAT GENET 1993;4 (4):431-431
Caron H, van Sluis P, van Hoeve M, de Kraker J, Bras J, Slater R, Mannens M, Voûte PA, Westerveld A, Versteeg R, Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification. NAT GENET 1993;4 (2):187-190 [PubMed]
Caron HN, Abeling N, van Gennip A, de Kraker J, Voûte PA, Hyperaminoaciduria identifies patients at risk of developing renal tubular toxicity associated with ifosfamide and platinate containing regimens. MED PEDIATR ONCOL 1992;20 (1):42-47 [PubMed]
Key publications

Molenaar JJ, Domingo-Fernández R, Ebus ME, Lindner S, Koster J, Drabek K, Mestdagh P, van Sluis P, Valentijn LJ, van Nes J, Broekmans M, Haneveld F, Volckmann R, Bray I, Heukamp L, Sprüssel A, Thor T, Kieckbusch K, Klein-Hitpass L, Fischer M, Vandesompele J, Schramm A, van Noesel MM, Varesio L, Speleman F, Eggert A, Stallings RL, Caron HN, Versteeg R, Schulte JH, LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression. NAT GENET 2012;44 (11):1199-1206 [PubMed]
Stutterheim J, Ichou FA, den Ouden E, Versteeg R, Caron HN, Tytgat GAM, van der Schoot CE, Methylated RASSF1a Is the First Specific DNA Marker for Minimal Residual Disease Testing in Neuroblastoma. CLIN CANCER RES 2012;18 (3):808-814 [PubMed]
van der Pal HJ, van Dalen EC, van Delden E, van Dijk IW, Kok WE, Geskus RB, Sieswerda E, Oldenburger F, Koning CC, van Leeuwen FE, Caron HN, Kremer LC, High Risk of Symptomatic Cardiac Events in Childhood Cancer Survivors. J CLIN ONCOL 2012;30 (13):1429-1437 [PubMed]
Molenaar JJ, Ebus ME, Geerts D, Koster J, Lamers F, Valentijn LJ, Westerhout EM, Versteeg R, Caron HN, Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells. P NATL ACAD SCI USA 2009;106 (31):12968-12973 [PubMed]
Stutterheim J, Gerritsen A, Zappeij-Kannegieter L, Kleijn I, dee R, Hooft L, van Noesel MM, Bierings M, Berthold F, Versteeg R, Caron HN, van der Schoot CE, Tytgat GAM, PHOX2B Is a Novel and Specific Marker for Minimal Residual Disease Testing in Neuroblastoma. J CLIN ONCOL 2008;26 (33):5443-5449 [PubMed]


All Publications

Research programmes

Paediatric Oncology; biology and clinical

  1. Translational tumour biology (a.o. targetted drugs, MRD, tumor predisposition) (collaboration lab.Human Genetics, AMC)
  2. Clinical trials, incl. phase 1/2
  3. Evidence-base for Paediatric Oncology (a.o. Cochrane Childhood Cancer Systematic Review Group and guideline development)
  4. Long-term effects in survivors of paediatric cancer
  5. Psychosocial consequences of childhood cancer (PI = Dr.M.Grootenhuis, EKZ AMC)

Faculty
Prof. dr. H.N. Caron MD PhD
Dr. H. van den Berg MD PhD
Dr. C. van den Bos MD PhD
Dr. W.B. Breunis MD PhD
Prof. dr. M.A. Grootenhuis MSc PhD
Dr. L.M. Haveman MD PhD
Dr. T. Israëls MD PhD
Dr. L.C.M. Kremer MD PhD
Dr. J.H.M. Merks MD PhD
Dr. A.Y.N. Schouten-van Meeteren MD PhD
Dr. G.A.M. Tytgat MD PhD
Dr. M.D. van de Wetering MD PhD
Dr. J. Zsiros MD PhD
Prof. C.M. Zwaan MD PhD

Postdocs
Dr. E.C. van Dalen MD PhD
Dr. J.J. Molenaar MD PhD

PhD Students
Drs. O.G. Besançon
Drs. N.K.A. van Eijkelenburg MD
A. Hakkert
Drs. S.M.P.D. Keizer MD
Drs. R.R.G. Knops
Drs. J.L. Kok
A.M.J.B. Smets MD
Drs. N. Streefkerk MSc
Drs. J.C. Teepen MD (LUMC Leiden)
B. Vaarwerk
Drs. J. van Wijk
Drs. M.M. Geenen
Drs. J.H.C. Kok

Others
Dr. A.C. Verschuur MD PhD
Prof. dr. R. Versteeg

Other research related activities
  • Membership of medical or scientific committee, KWF Kankerbestrijding, Wetenschappelijke Raad
  • Membership of medical or scientific committee, KWF Kankerbestrijding, Beoordelingscommissie TTO
  • Membership of medical or scientific committee, University of Amsterdam, AMC Research Council
  • Membership of editorial board / Editorship, EUROPEAN JOURNAL OF CANCER
  • Membership of editorial board / Editorship, PEDIATRIC BLOOD & CANCER
  • Board of directors / Trustees / Supervisory board, Other
  • Membership of medical or scientific committee, DCOG (Dutch Childhood Oncology Group), LATER research group,
  • Membership of medical or scientific committee, DCOG (Dutch Childhood Oncology Group), New Agents Group
  • Contribution to guidelines and protocols, DCOG guidelines for longterm follow-up
  • Contribution to training of professionals, ASPO (Amsterdam School of Paediatric Oncology)
Current research funding
  • AMC
  • Erasmus MC
  • Genzyme Europe BV
  • Institute Gustave Roussy
  • Sanquin Blood Supply Foundation
  • Stichting KIKA
  • Stichting Kinderoncologie Nederland