• Principal Investigator
  • Female

Dr. A.C. Heijboer PhD

Position:
Main activities: Patient care, Research
Specialisation:
foto A.C. Heijboer is one of the AMC Principal Investigators
Focus of research:
AMC themes: Metabolic disorders and gastrointestinal diseases, Other Research
Departments: Clinical Chemistry: Laboratory for Endocrinology
Hillebrand JJ, Heijboer AC, Endert E, Effects of repeated freeze-thaw cycles on endocrine parameters in plasma and serum. ANN CLIN BIOCHEM 2017;54 (2):289-292 [PubMed]
Lerchbaum E, Pilz S, Trummer C, Schwetz V, Pachernegg O, Heijboer AC, Obermayer-Pietsch B, Vitamin D and Testosterone in Healthy Men: A Randomized Controlled Trial. J CLIN ENDOCR METAB 2017;102 (11):4292-4302 [PubMed]
van Andel M, Drent ML, van Herwaarden AE, Ackermans MT, Heijboer AC, A method comparison of total and HMW adiponectin: HMW/total adiponectin ratio varies versus total adiponectin, independent of clinical condition. CLIN CHIM ACTA 2017;465:30-33 [PubMed]
van den Reek JMPA, Menting SP, Janssen WWL, Dhaliwal R, Heijboer AC, van Herwaarden AE, Sweep FCGJ, de Jong LM, Tjwa ET, Otero ME, Spuls PI, de Jong EMGJ, Procollagen-3 N-terminal peptide measurements for the detection of liver fibrosis in methotrexate-treated patients with psoriasis: daily practice use and clinical implications. BRIT J DERMATOL 2017;ahead of print [PubMed]
van der Sluis TM. New insights in steroid hormone metabolism in prostate cancer. S.l.: s.n.; 2017. -p. Proefschrift Vrije Universiteit, Faculteit Geneeskunde. (Promotor(s): Meuleman EJ, van Moorselaar RJ; copromotor(s): Vis AN, Heijboer AC)
van der Voorn B, de Waard M, Dijkstra LR, Heijboer AC, Rotteveel J, van Goudoever JB, Finken MJJ, Stability of Cortisol and Cortisone in Human Breast Milk During Holder Pasteurization. J PEDIATR GASTR NUTR 2017;ahead of print [PubMed]
Vlot MC, Klink DT, den Heijer M, Blankenstein MA, Rotteveel J, Heijboer AC, Effect of pubertal suppression and cross-sex hormone therapy on bone turnover markers and bone mineral apparent density (BMAD) in transgender adolescents. BONE 2017;95:11-19 [PubMed]
Wirix AJG, Finken MJJ, Von Rosenstiel-Jadoul IA, Heijboer AC, Nauta J, Groothoff JW, Chinapaw MJM, Kist-van Holthe JE, Is there an association between cortisol and hypertension in overweight or obese children?. J CLIN RES PEDIATR E 2017;-:- [PubMed]
Adema AY, van Ittersum FJ, Hoenderop JG, de Borst MH, Nanayakkara PW, ter Wee PM, Heijboer AC, Vervloet MG [Contributors: Bindels R, Hoenderop JG, de Borst MH, Hillebrands JL, Navis GJ, ter Wee PM, Vervloet MG]] , Reduction of Oxidative Stress in Chronic Kidney Disease Does Not Increase Circulating α-Klotho Concentrations. PLOS ONE 2016;11 (1):e0144121 [PubMed]
Bekkach Y, Heijboer AC, Endert E, Ackermans MT, Determination of urinary aldosterone using a plasma aldosterone 2D ID LC-MS/MS method. BIOANALYSIS 2016;8 (17):1765-1775 [PubMed]
Büttler RM. Measurement of Adrenal Steroid Hormones. Method Development, Validation and Application. S.l.: s.n.; 2016. 208p. ISBN 94-028-0116-2 Proefschrift Vrije Universiteit, Faculteit Geneeskunde. (Promotor(s): Blankenstein MA; copromotor(s): Heijboer AC)
Büttler RM, Martens F, Ackermans MT, Davison AS, van Herwaarden AE, Kortz L, Krabbe JG, Lentjes EGW, Syme C, Webster R, Blankenstein MA, Heijboer AC, Comparison of eight routine unpublished LC-MS/MS methods for the simultaneous measurement of testosterone and androstenedione in serum. CLIN CHIM ACTA 2016;454:112-118 [PubMed]
Büttler RM, Peper JS, Crone EA, Lentjes EGW, Blankenstein MA, Heijboer AC, Reference values for salivary testosterone in adolescent boys and girls determined using Isotope-Dilution Liquid-Chromatography Tandem Mass Spectrometry (ID-LC-MS/MS). CLIN CHIM ACTA 2016;456:15-18 [PubMed]
Dirks NF, Martens F, Vanderschueren D, Billen J, Pauwels S, Ackermans MT, Endert E, Heijer Md, Blankenstein MA, Heijboer AC, Determination of human reference values for serum total 1,25-dihydroxyvitamin D using an extensively validated 2D ID-UPLC-MS/MS method. J STEROID BIOCHEM 2016;164:127-133 [PubMed]
Dirks NF, Vesper HW, van Herwaarden AE, van den Ouweland JMW, Kema IP, Krabbe JG, Heijboer AC, Various calibration procedures result in optimal standardization of routinely used 25(OH)D ID-LC-MS/MS methods. CLIN CHIM ACTA 2016;462:49-54 [PubMed]
Finken MJJ, van der Voorn B, Heijboer AC, de Waard M, van Goudoever JB, Rotteveel J, Glucocorticoid Programming in Very Preterm Birth. HORM RES PAEDIAT 2016;85 (4):221-231 [PubMed]
Heijboer AC, Savelkoul E, Kruit A, Endert E, Blankenstein MA, Inaccurate First-Generation Testosterone Assays Are Influenced by Sex Hormone-Binding Globulin Concentrations. J APPL LAB MED 2016;1 (2):194-201
Limonard EJ, Schoenmaker T, de Vries TJ, Tanck MW, Heijboer AC, Endert E, Fliers E, Everts V, Bisschop PH, Clonidine increases bone resorption in humans. OSTEOPOROSIS INT 2016;27 (3):1063-1071 [PubMed]
Luttikhold J, van Norren K, Rijna H, Buijs N, Ankersmit M, Heijboer AC, Gootjes J, Hartmann B, Holst JJ, van Loon LJ, van Leeuwen PA, Jejunal feeding is followed by a greater rise in plasma cholecystokinin, peptide YY, glucagon-like peptide 1, and glucagon-like peptide 2 concentrations compared with gastric feeding in vivo in humans: a randomized trial. AM J CLIN NUTR 2016;103 (2):435-443 [PubMed]
Man PW, Lin W, van der Meer IM, Heijboer AC, Wolterbeek R, Numans ME, Middelkoop BJC, Lips P, Vitamin D status in the Chinese population in the Netherlands: The DRAGON study. J STEROID BIOCHEM 2016;164:194-198 [PubMed]
ter Horst KW, Versteeg RI, Gilijamse PW, Ackermans MT, Heijboer AC, Romijn JA, La Fleur SE, Trinko R, DiLeone RJ, Serlie MJ, The vitamin D metabolites 25(OH)D and 1,25(OH)2D are not related to either glucose metabolism or insulin action in obese women. DIABETES METAB 2016;42 (6):416-423 [PubMed]
Tromp IIM, Franco OH, van den Hooven EH, Heijboer AC, Jaddoe VWV, Duijts L, de Jongste JC, Moll HA, Kiefte-de Jong JC, 25-Hydroxyvitamin D concentrations, asthma and eczema in childhood: The generation R study. CLIN NUTR 2016;ahead of print [PubMed]
van der Meijden K, Bakker AD, van Essen HW, Heijboer AC, Schulten EAJM, Lips P, Bravenboer N, Mechanical loading and the synthesis of 1,25(OH)2D in primary human osteoblasts. J STEROID BIOCHEM 2016;156:32-39 [PubMed]
van der Meijden K, Bravenboer N, Dirks NF, Heijboer AC, den Heijer M, de Wit GMJ, Offringa C, Lips P, Jaspers RT, Effects of 1,25(OH)2 D3 and 25(OH)D3 on C2C12 Myoblast Proliferation, Differentiation, and Myotube Hypertrophy. J CELL PHYSIOL 2016;231 (11):2517-2528 [PubMed]
van der Voorn B, de Waard M, van Goudoever JB, Rotteveel J, Heijboer AC, Finken MJ, Breast-Milk Cortisol and Cortisone Concentrations Follow the Diurnal Rhythm of Maternal Hypothalamus-Pituitary-Adrenal Axis Activity. J NUTR 2016;146 (11):2174-2179 [PubMed]
Adema AY, Vervloet MG, Blankenstein MA, Heijboer AC, α-Klotho is unstable in human urine. KIDNEY INT 2015;88 (6):1442-1444 [PubMed]
Bui HN, Sluss PM, Hayes FJ, Blincko S, Knol DL, Blankenstein MA, Heijboer AC, Testosterone, free testosterone, and free androgen index in women: Reference intervals, biological variation, and diagnostic value in polycystic ovary syndrome. CLIN CHIM ACTA 2015;450:227-232 [PubMed]
Büttler RM, Martens F, Fanelli F, Pham HT, Kushnir MM, Janssen MJW, Owen L, Taylor AE, Soeborg T, Blankenstein MA, Heijboer AC, Comparison of 7 Published LC-MS/MS Methods for the Simultaneous Measurement of Testosterone, Androstenedione, and Dehydroepiandrosterone in Serum. CLIN CHEM 2015;61 (12):1475-1483 [PubMed]
Büttler RM, Martens F, Kushnir MM, Ackermans MT, Blankenstein MA, Heijboer AC, Simultaneous measurement of testosterone, androstenedione and dehydroepiandrosterone (DHEA) in serum and plasma using Isotope-Dilution 2-Dimension Ultra High Performance Liquid-Chromatography Tandem Mass Spectrometry (ID-LC-MS/MS). CLIN CHIM ACTA 2015;438:157-159 [PubMed]
de Koning EJ, van Schoor NM, Penninx BWJH, Elders PJM, Heijboer AC, Smit JH, Bet PM, van Tulder MW, den Heijer M, van Marwijk HWJ, Lips P, Vitamin D supplementation to prevent depression and poor physical function in older adults: Study protocol of the D-Vitaal study, a randomized placebo-controlled clinical trial. BMC GERIATR 2015;15:151 [PubMed]
Emmen JMA, Heijboer AC, de Jong SM, Endert E, Glucagon stability anno 2014. CLIN CHIM ACTA 2015;440:1-2 [PubMed]
Heijboer AC, Oosterwerff M, Schroten NF, Eekhoff EMW, Chel VGM, de Boer RA, Blankenstein MA, Lips P, Vitamin D supplementation and testosterone concentrations in male human subjects. CLIN ENDOCRINOL 2015;83 (1):105-110 [PubMed]
Klink D, Caris M, Heijboer A, van Trotsenburg M, Rotteveel J, Bone Mass in Young Adulthood Following Gonadotropin-Releasing Hormone Analog Treatment and Cross-Sex Hormone Treatment in Adolescents With Gender Dysphoria. J CLIN ENDOCR METAB 2015;100 (2):E270-E275
Limonard EJ, Veldhuis-Vlug AG, van Dussen L, Runge JH, Tanck MW, Endert E, Heijboer AC, Fliers E, Hollak CE, Akkerman EM, Bisschop PH, Short-Term Effect of Estrogen on Human Bone Marrow Fat. J BONE MINER RES 2015;30 (11):2058-2066 [PubMed]
Luttikhold J, van Norren K, Buijs N, Ankersmit M, Heijboer AC, Gootjes J, Rijna H, van Leeuwen PAM, van Loon LJC, Jejunal Casein Feeding Is Followed by More Rapid Protein Digestion and Amino Acid Absorption When Compared with Gastric Feeding in Healthy Young Men. J NUTR 2015;145 (9):2033-2038 [PubMed]
Teunissen CE, van der Flier WM, Scheltens P, Duits A, Wijnstok N, Nijpels G, Dekker JM, Blankenstein RMA, Heijboer AC, Serum leptin is not altered nor related to cognitive decline in Alzheimer's disease. J ALZHEIMERS DIS 2015;44 (3):809-813 [PubMed]
van der Voorn B, Martens F, Peppelman NS, Rotteveel J, Blankenstein MA, Finken MJJ, Heijboer AC, Determination of cortisol and cortisone in human mother's milk. CLIN CHIM ACTA 2015;444:154-155 [PubMed]
Veldhuis-Vlug AG, Tanck MW, Limonard EJ, Endert E, Heijboer AC, Lips P, Fliers E, Bisschop PH, The effects of beta-2 adrenergic agonist and antagonist on human bone metabolism: a randomized controlled trial. BONE 2015;71:196-200 [PubMed]
Voortman T, van den Hooven EH, Heijboer AC, Hofman A, Jaddoe VW, Franco OH, Vitamin D deficiency in school-age children is associated with sociodemographic and lifestyle factors. J NUTR 2015;145 (4):791-798 [PubMed]
Heijboer AC, Zimmerman Y, de Boer T, Coelingh Bennink H, Blankenstein MA, Peculiar observations in measuring testosterone in women treated with oral contraceptives supplemented with dehydroepiandrosterone (DHEA). CLIN CHIM ACTA 2014;430:92-95 [PubMed]
Lerchbaum E, Pilz S, Trummer C, Rabe T, Schenk M, Heijboer AC, Obermayer-Pietsch B, Serum vitamin D levels and hypogonadism in men. ANDROLOGY-US 2014;2 (5):748-754 [PubMed]
Milaneschi Y, Hoogendijk W, Lips P, Heijboer AC, Schoevers R, van Hemert AM, Beekman ATF, Smit JH, Penninx BWJH, The association between low vitamin D and depressive disorders. MOL PSYCHIATR 2014;19 (4):444-451 [PubMed]
van der Meijden K, Lips P, van Driel M, Heijboer AC, Schulten EAJM, den Heijer M, Bravenboer N, Primary human osteoblasts in response to 25-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3. PLOS ONE 2014;9 (10):e110283 [PubMed]
van Golen LW, Veltman DJ, IJzerman RG, Deijen JB, Heijboer AC, Barkhof F, Drent ML, Diamant M, Effects of insulin detemir and NPH insulin on body weight and appetite-regulating brain regions in human type 1 diabetes: a randomized controlled trial. PLOS ONE 2014;9 (4):e94483 [PubMed]
van Grootheest G, Milaneschi Y, Lips PTAM, Heijboer AC, Smit JH, Penninx BWJH, Determinants of plasma 25-hydroxyvitamin D levels in healthy adults in the Netherlands. NETH J MED 2014;72 (10):533-540 [PubMed]
van Schoor NM, Knol DL, Deeg DJH, Peters FPAMN, Heijboer AC, Lips P, Longitudinal changes and seasonal variations in serum 25-hydroxyvitamin D levels in different age groups: results of the Longitudinal Aging Study Amsterdam. OSTEOPOROSIS INT 2014;25 (5):1483-1491 [PubMed]
Brouwer IA, Geleijnse JM, Klaasen VM, Smit LA, Giltay EJ, de Goede J, Heijboer AC, Kromhout D, Katan MB, Effect of alpha linolenic acid supplementation on serum prostate specific antigen (PSA): results from the alpha omega trial. PLOS ONE 2013;8 (12):e81519 [PubMed]
Bui HN. Measuring Testosterone; the Power of a ‘Method on Steroids'. S.l.: s.n.; 2013. 130p. ISBN 978-94-6191-958-8 Proefschrift Vrije Universiteit, Faculteit Geneeskunde. (Promotor(s): Blankenstein MA; copromotor(s): Heijboer AC, Struys EA)
Bui HN, Blankenstein MA, Heijboer AC, Isotopically labelled testosterone derivatives as internal standards in liquid chromatography-tandem mass spectrometry. ANN CLIN BIOCHEM 2013;50 (3):275-276 [PubMed]
Bui HN, Schagen SEE, Klink DT, Delemarre-van de Waal HA, Blankenstein MA, Heijboer AC, Salivary testosterone in female-to-male transgender adolescents during treatment with intra-muscular injectable testosterone esters. STEROIDS 2013;78 (1):91-95 [PubMed]
Bui HN, Sluss PM, Blincko S, Knol DL, Blankenstein MA, Heijboer AC, Dynamics of serum testosterone during the menstrual cycle evaluated by daily measurements with an ID-LC-MS/MS method and a 2nd generation automated immunoassay. STEROIDS 2013;78 (1):96-101 [PubMed]
Buizert PJ, van Schoor NM, Simsek S, Lips P, Heijboer AC, den Heijer M, Deeg DJH, Eekhoff EMW, PTH: a new target in arteriosclerosis?. J CLIN ENDOCR METAB 2013;98 (10):E1583-E1590 [PubMed]
Büttler RM, Kruit A, Blankenstein MA, Heijboer AC, Measurement of dehydroepiandrosterone sulphate (DHEAS): a comparison of Isotope-Dilution Liquid Chromatography Tandem Mass Spectrometry (ID-LC-MS/MS) and seven currently available immunoassays. CLIN CHIM ACTA 2013;424:22-26 [PubMed]
Deckers MML, de Jongh RT, Lips PTAM, Penninx BWJH, Milaneschi Y, Smit JH, van Schoor NM, Blankenstein MA, Heijboer AC, Prevalence of vitamin D deficiency and consequences for PTH reference values. CLIN CHIM ACTA 2013;426:41-45 [PubMed]
de Jongh RT, Vervloet MG, Bravenboer N, Heijboer AC, den Heijer M, Lips P, Chronische botpijn door verhoogde FGF23-productie? Het belang van een fosfaatbepaling. NED TIJDSCHR GENEESKD 2013;157 (28):A5908 [PubMed]
de Jong M, Rotteveel J, Heijboer AC, Cranendonk A, Twisk JWR, van Weissenbruch MM, Urine gonadotropin and estradiol levels in female very-low-birth-weight infants. EARLY HUM DEV 2013;89 (3):131-135 [PubMed]
Depreter B, Heijboer AC, Langlois MR, Accuracy of three automated 25-hydroxyvitamin D assays in hemodialysis patients. CLIN CHIM ACTA 2013;415:255-260 [PubMed]
Deurloo KL, Linskens IH, Heymans MW, Heijboer AC, Blankenstein MA, van Vugt JMG, ADAM12s and PP13 as first trimester screening markers for adverse pregnancy outcome. CLIN CHEM LAB MED 2013;51 (6):1279-1284 [PubMed]
Heijboer AC, Blankenstein MA, Hoenderop J, de Borst MH, Vervloet MG, Laboratory aspects of circulating alpha-Klotho. NEPHROL DIAL TRANSPL 2013;28 (9):2283-2287 [PubMed]
Oonincx DGAB, van de Wal MD, Bosch G, Stumpel JBG, Heijboer AC, van Leeuwen JPTM, Hendriks WH, Kik M, Blood vitamin D(3) metabolite concentrations of adult female bearded dragons (Pogona vitticeps) remain stable after ceasing UVb exposure. COMP BIOCHEM PHYS B 2013;165 (3):196-200 [PubMed]
Peper JS, Mandl RCW, Braams BR, de Water E, Heijboer AC, Koolschijn PCMP, Crone EA, Delay discounting and frontostriatal fiber tracts: a combined DTI and MTR study on impulsive choices in healthy young adults. CEREB CORTEX 2013;23 (7):1695-1702 [PubMed]
Sohl E, de Jongh RT, Heijboer AC, Swart KMA, Brouwer-Brolsma EM, Enneman AW, de Groot CPGM, van der Velde N, Dhonukshe-Rutten RAM, Lips P, van Schoor NM, Vitamin D status is associated with physical performance: the results of three independent cohorts. OSTEOPOROSIS INT 2013;24 (1):187-196 [PubMed]
Terwijn M, van Schie A, Blankenstein MA, Heijboer AC, Pregnancy detection by quantitative urine hCG analysis: the need for a lower cut-off. CLIN CHIM ACTA 2013;424:174 [PubMed]
van de Lagemaat M, Rotteveel J, Heijboer AC, Lafeber HN, van Weissenbruch MM, Growth in preterm infants until six months postterm: the role of insulin and IGF-I. HORM RES PAEDIAT 2013;80 (2):92-99 [PubMed]
van der Sluis TM, van Moorselaar RJA, Meuleman EJH, ter Haar RW, Bui HN, Heijboer AC, Vis AN, Relationship between body mass index and serum testosterone concentration in patients receiving luteinizing hormone-releasing hormone agonist therapy for prostate cancer. UROLOGY 2013;81 (5):1005-1009 [PubMed]
Büttler RM, Struys EA, Addie R, Blankenstein MA, Heijboer AC, Measurement of dehydroepiandrosterone sulfate (DHEAS) in serum and cerebrospinal fluid by isotope-dilution liquid chromatography tandem mass spectrometry. CLIN CHIM ACTA 2012;414:246-247 [PubMed]
de Jong M, Rotteveel J, Heijboer AC, Cranendonk A, Twisk JWR, van Weissenbruch MM, Urine gonadotropin and testosterone levels in male very-low-birthweight infants. HORM RES PAEDIAT 2012;78 (3):173-179 [PubMed]
Giltay EJ, Geleijnse JM, Heijboer AC, de Goede J, Oude Griep LM, Blankenstein MA, Kromhout D, No effects of n-3 fatty acid supplementation on serum total testosterone levels in older men: the Alpha Omega Trial. INT J ANDROL 2012;35 (5):680-687 [PubMed]
Groenestege WMT, Bui HN, ten Kate J, Menheere PPCA, Oosterhuis WP, Vader HL, Heijboer AC, Janssen MJW, Accuracy of first and second generation testosterone assays and improvement through sample extraction. CLIN CHEM 2012;58 (7):1154-1156 [PubMed]
Heijboer AC, Blankenstein MA, Kema IP, Buijs MM, Accuracy of 6 routine 25-hydroxyvitamin D assays: influence of vitamin D binding protein concentration. CLIN CHEM 2012;58 (3):543-548 [PubMed]
Janssen MJW, Wielders JPM, Bekker CC, Boesten LSM, Buijs MM, Heijboer AC, van der Horst FAL, Loupatty FJ, van den Ouweland JMW, Multicenter comparison study of current methods to measure 25-hydroxyvitamin D in serum. STEROIDS 2012;77 (13):1366-1372 [PubMed]
Morota K, Komori M, Fujinami R, Yamada K, Kuribayashi K, Watanabe N, Sokoll LJ, Elliott D, Chan DW, Martens F, Heijboer AC, Blankenstein MA, Hershberger SJ, Pfeiffer ZA, Vaidya SV, Dowell BL, Improvement and multicenter evaluation of the analytical performance of an automated chemiluminescent immunoassay for alpha fetoprotein. INT J BIOL MARKER 2012;27 (1):39-46 [PubMed]
van der Sluis TM, Bui HN, Meuleman EJH, Heijboer AC, Hartman JF, van Adrichem N, Boevé E, de Ronde W, van Moorselaar RJA, Vis AN, Lower testosterone levels with luteinizing hormone-releasing hormone agonist therapy than with surgical castration: new insights attained by mass spectrometry. J UROLOGY 2012;187 (5):1601-1606 [PubMed]
van der Sluis TM, Meuleman EJH, van Moorselaar RJA, Bui HN, Blankenstein MA, Heijboer AC, Vis AN, Intraprostatic testosterone and dihydrotestosterone. Part II: concentrations after androgen hormonal manipulation in men with benign prostatic hyperplasia and prostate cancer. BJU INT 2012;109 (2):183-188 [PubMed]
van der Sluis TM, Vis AN, van Moorselaar RJA, Bui HN, Blankenstein MA, Meuleman EJH, Heijboer AC, Intraprostatic testosterone and dihydrotestosterone. Part I: concentrations and methods of determination in men with benign prostatic hyperplasia and prostate cancer. BJU INT 2012;109 (2):176-182 [PubMed]
Veldhuis-Vlug AG, El Mahdiui M, Endert E, Heijboer AC, Fliers E, Bisschop PH, Bone Resorption Is Increased in Pheochromocytoma Patients and Normalizes following Adrenalectomy. J CLIN ENDOCR METAB 2012;97 (11):E2093-E2097 [PubMed]
Vervloet MG, van Zuilen AD, Heijboer AC, ter Wee PM, Bots ML, Blankestijn PJ, Wetzels JFM [Contributors: Blankestijn P, van Zuilen A, Wierdsma J, Wetzels J, Vervoort G, Mooren S, ten Dam M, Boom M, Kaasjager K, Lensen L, Wieleman A, van Buren M, Vleming L, Bergsma H, Schoenmakers K, Sypkens Y, Berkhout N, van de Ven P, Gundlach P, Sluiter H, Wolters E]] , Fibroblast growth factor 23 is associated with proteinuria and smoking in chronic kidney disease: an analysis of the MASTERPLAN cohort. BMC NEPHROL 2012;13:20 [PubMed]
de Ronde W, Vogel S, Bui HN, Heijboer AC, Reduction in 24-Hour Plasma Testosterone Levels in Subjects Who Showered 15 or 30 Minutes After Application of Testosterone Gel. PHARMACOTHERAPY 2011;31 (3):248-252 [PubMed]
Eekman DA, Bultink IEM, Heijboer AC, Dijkmans BAC, Lems WF, Bone turnover is adequately suppressed in osteoporotic patients treated with bisphosphonates in daily practice. BMC MUSCULOSKEL DIS 2011;12:167 [PubMed]
Engels MAJ, Heijboer AC, Blankenstein MA, van Vugt JMG, Performance of first-trimester combined test for Down syndrome in different maternal age groups: reason for adjustments in screening policy?. PRENATAL DIAG 2011;31 (13):1241-1245 [PubMed]
Heijboer AC, Frans A, Lomecky M, Blankenstein MA, Analysis of glucagon-like peptide 1; what to measure?. CLIN CHIM ACTA 2011;412 (13-14):1191-1194 [PubMed]
Heijboer AC, Martens F, Mulder SD, Schats R, Blankenstein MA, Interference in human chorionic gonadotropin (hCG) analysis by macro-hCG. CLIN CHIM ACTA 2011;412 (23-24):2349-2350 [PubMed]
Molenaar N, Johan Groeneveld AB, Dijstelbloem HM, de Jong MFC, Girbes ARJ, Heijboer AC, Beishuizen A, Assessing adrenal insufficiency of corticosteroid secretion using free versus total cortisol levels in critical illness. INTENS CARE MED 2011;37 (12):1986-1993 [PubMed]
Vandenberghe G, Mensink I, Twisk JWR, Blankenstein MA, Heijboer AC, van Vugt JMG, First trimester screening for intra-uterine growth restriction and early-onset pre-eclampsia. PRENATAL DIAG 2011;31 (10):955-961 [PubMed]
Vermeulen MAR, Richir MC, Garretsen MK, van Schie A, Ghatei MA, Holst JJ, Heijboer AC, Uitdehaag BMJ, Diamant M, Eekhoff EMW, van Leeuwen PAM, Ligthart-Melis GC, Gastric emptying, glucose metabolism and gut hormones: evaluation of a common preoperative carbohydrate beverage. NUTRITION 2011;27 (9):897-903 [PubMed]
Vervloet MG, van Ittersum FJ, Büttler RM, Heijboer AC, Blankenstein MA, ter Wee PM, Effects of dietary phosphate and calcium intake on fibroblast growth factor-23. CLIN J AM SOC NEPHRO 2011;6 (2):383-389 [PubMed]
Heijboer AC, Bouman AA, Blankenstein MA, Roelandse-Koop EA, Intralipid causes falsely increased glucose concentrations with the Hemocue glucose analyzer. CLIN CHEM LAB MED 2010;48 (5):737-738 [PubMed]
Linskens IH, Engels M, Oepkes D, Heijboer AC, Blankenstein MA, van Vugt JMG, A trend toward increased first trimester free beta-hCG and PAPP-A in monochorionic twins complicated by Twin-to-Twin Transfusion syndrome. PRENATAL DIAG 2010;30 (9):909-910 [PubMed]
Struys EA, Heijboer AC, van Moorselaar J, Jakobs C, Blankenstein MA, Serum sarcosine is not a marker for prostate cancer. ANN CLIN BIOCHEM 2010;47 (Part 3):282 [PubMed]
van der Meij BS, Langius JAE, Smit EF, Spreeuwenberg MD, von Blomberg BME, Heijboer AC, Paul MA, van Leeuwen PAM, Oral Nutritional Supplements Containing (n-3) Polyunsaturated Fatty Acids Affect the Nutritional Status of Patients with Stage III Non-Small Cell Lung Cancer during Multimodality Treatment. J NUTR 2010;140 (10):1774-1780 [PubMed]
Heijboer AC, Ijzerman RG, Bouman AA, Blankenstein MA, Two cases of antiruthenium antibody interference in Modular free thyroxine assay. ANN CLIN BIOCHEM 2009;46 (Part 3):263-264 [PubMed]
Heijboer AC, Levitus M, Vervloet MG, Lips P, ter Wee PM, Dijstelbloem HM, Blankenstein MA, Determination of fibroblast growth factor 23. ANN CLIN BIOCHEM 2009;46 (Part 4):338-340 [PubMed]
Heijboer AC, Martens F, Blankenstein MA, Measuring salivary cortisol with the Architect i2000 random access analyser. ANN CLIN BIOCHEM 2009;46 (Part 3):261-262 [PubMed]
Heijboer AC, Netelenbos JC, Blankenstein MA, Meningioma in untreated congenital adrenal hyperplasia: a relationship?. J NEURO-ONCOL 2009;92 (2):223-225 [PubMed]
Linskens IH, Beertsen CMT, van Vugt JMG, Blankenstein MA, Heijboer AC, Processing effects and storage conditions on A Disintegrin And Metalloprotease (ADAM12s), a maternal serum marker for adverse pregnancy outcome. CLIN CHEM LAB MED 2009;47 (12):1579-1581 [PubMed]
Heijboer AC, Otten JH, Jelles WJ, Blankenstein MA, Vroonhof K, Importance of sample size in hospital point-of-care glucose measurements. CLIN CHEM LAB MED 2008;46 (6):874-875 [PubMed]
Parlevliet ET, Heijboer AC, Schröder-van der Elst JP, Havekes LM, Romijn JA, Pijl H, Corssmit EPM, Oxyntomodulin ameliorates glucose intolerance in mice fed a high-fat diet. AM J PHYSIOL-ENDOC M 2008;294 (1):E142-E147 [PubMed]
van den Hoek AM, Heijboer AC, Voshol PJ, Havekes LM, Romijn JA, Corssmit EPM, Pijl H, Chronic PYY3-36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice. AM J PHYSIOL-ENDOC M 2007;292 (1):E238-E245 [PubMed]
Heemstra KA, Smit JWA, Eustatia-Rutten CFA, Heijboer AC, Frölich M, Romijn JA, Corssmit EPM, Glucose tolerance and lipid profile in longterm exogenous subclinical hyperthyroidism and the effects of restoration of euthyroidism, a randomised controlled trial. CLIN ENDOCRINOL 2006;65 (6):737-744 [PubMed]
Heijboer AC, Pijl H, van den Hoek AM, Havekes LM, Romijn JA, Corssmit EPM, Gut-brain axis: regulation of glucose metabolism. J NEUROENDOCRINOL 2006;18 (12):883-894 [PubMed]
Heijboer AC, van den Hoek AM, Parlevliet ET, Havekes LM, Romijn JA, Pijl H, Corssmit EPM, Ghrelin differentially affects hepatic and peripheral insulin sensitivity in mice. DIABETOLOGIA 2006;49 (4):732-738 [PubMed]
Heijboer AC, Donga E, Voshol PJ, Dang ZC, Havekes LM, Romijn JA, Corssmit EPM, Sixteen hours of fasting differentially affects hepatic and muscle insulin sensitivity in mice. J LIPID RES 2005;46 (3):582-588 [PubMed]
Heijboer AC, van den Hoek AM, Pijl H, Voshol PJ, Havekes LM, Romijn JA, Corssmit EPM, Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice. DIABETOLOGIA 2005;48 (8):1621-1626 [PubMed]
Heijboer AC, Voshol PJ, Donga E, van Eden CG, Havekes LM, Romijn JA, Pijl H, Corssmit EPM, High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. PEPTIDES 2005;26 (12):2554-2558 [PubMed]
van den Hoek AM, Heijboer AC, Corssmit EPM, Voshol PJ, Romijn JA, Havekes LM, Pijl H, PYY3-36 reinforces insulin action on glucose disposal in mice fed a high-fat diet. DIABETES 2004;53 (8):1949-1952 [PubMed]
de Groot PCE, Hjeltnes N, Heijboer AC, Stal W, Birkeland K, Effect of training intensity on physical capacity, lipid profile and insulin sensitivity in early rehabilitation of spinal cord injured individuals. SPINAL CORD 2003;41 (12):673-679 [PubMed]
Key publications

Büttler RM, Martens F, Fanelli F, Pham HT, Kushnir MM, Janssen MJW, Owen L, Taylor AE, Soeborg T, Blankenstein MA, Heijboer AC, Comparison of 7 Published LC-MS/MS Methods for the Simultaneous Measurement of Testosterone, Androstenedione, and Dehydroepiandrosterone in Serum. CLIN CHEM 2015;61 (12):1475-1483 [PubMed]
Dirks NF, Martens F, Vanderschueren D, Billen J, Pauwels S, Ackermans MT, Endert E, Heijer Md, Blankenstein MA, Heijboer AC, Determination of human reference values for serum total 1,25-dihydroxyvitamin D using an extensively validated 2D ID-UPLC-MS/MS method. J STEROID BIOCHEM 2016;164:127-133 [PubMed]
Heijboer AC, Blankenstein MA, Kema IP, Buijs MM, Accuracy of 6 routine 25-hydroxyvitamin D assays: influence of vitamin D binding protein concentration. CLIN CHEM 2012;58 (3):543-548 [PubMed]
Bui HN, Sluss PM, Blincko S, Knol DL, Blankenstein MA, Heijboer AC, Dynamics of serum testosterone during the menstrual cycle evaluated by daily measurements with an ID-LC-MS/MS method and a 2nd generation automated immunoassay. STEROIDS 2013;78 (1):96-101 [PubMed]
Heijboer AC, Blankenstein MA, Hoenderop J, de Borst MH, Vervloet MG, Laboratory aspects of circulating alpha-Klotho. NEPHROL DIAL TRANSPL 2013;28 (9):2283-2287 [PubMed]


All Publications

Research programmes

[no data]

Faculty
Dr. A.C. Heijboer PhD (VUmc)

PhD Students
Drs. N.F. Dirks MSc (VUmc)
S.R. Ursem (VUMC)
Drs. M.C. Vlot MD MSc (VUmc)

Other research related activities
  • None reported
Current research funding
  • None reported