• Female

Drs. C.J. Aalbers

Position: PhD student
Main activities: Research
Specialisation: Clinical immunology and rheumatology
foto
Focus of research:

Local gene therapy for rheumatoid arthritis

AMC themes: Infection & Immunity
Departments: Internal Medicine: Clinical Immunology and Rheumatology
Aalbers CJ, Broekstra N, van Geldorp M, Kramer E, Ramiro S, Tak PP, Vervoordeldonk MJ, Finn JD, Empty Capsids and Macrophage Inhibition/Depletion Increase rAAV Transgene Expression in Joints of Both Healthy and Arthritic Mice. HUM GENE THER 2017;28 (2):168-178 [PubMed]
Aalbers C, Gerlag D, Vos K, Vervoordeldonk M, Landewé R, Tak PP, Intra-articular etanercept treatment in inflammatory arthritis: A randomized double-blind placebo-controlled proof of mechanism clinical trial validating TNF as a potential therapeutic target for local treatment. JOINT BONE SPINE 2015;82 (5):338-344 [PubMed]
Aalbers CJ. Gene therapy for arthritis: progress towards a clinical trial. S.l.: s.n.; 2015. 196p. ISBN 978-94-6182-605-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Tak PP; copromotor(s): Vervoordeldonk MJBM)
Aalbers CJ, Bevaart L, Loiler S, de Cortie K, Wright JF, Mingozzi F, Tak PP, Vervoordeldonk MJ, Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-β (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis. PLOS ONE 2015;10 (6):e0130612 [PubMed]
Aalbers CJ, Gerlag DM, Vervoordeldonk MJ, Tak PP, Landewé RB, Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index. J RHEUMATOL 2015;42 (9):1672-1676 [PubMed]
Bevaart L, Aalbers CJ, Vierboom MPM, Broekstra N, Kondova I, Breedveld E, Hauck B, Wright JF, Tak PP, Vervoordeldonk MJ, Safety, Biodistribution, and Efficacy of an AAV-5 Vector Encoding Human Interferon-Beta (ART-I02) Delivered via Intra-Articular Injection in Rhesus Monkeys with Collagen-Induced Arthritis. HUM GENE THER CL DEV 2015;26 (2):103-112 [PubMed]
Aalbers CJ, Tak PP, Vervoordeldonk MJ, Advancements in adeno-associated viral gene therapy approaches: exploring a new horizon. F1000 MED REP 2011;3:17 [PubMed]
Aalbers CJ, Groen JL, Sivapalaratnam S, More outreach for young scientists. NATURE 2010;467 (7314):401 [PubMed]
Vervoordeldonk MJ, Aalbers CJ, Tak PP, Interferon beta for rheumatoid arthritis: new clothes for an old kid on the block. ANN RHEUM DIS 2009;68 (2):157-158 [PubMed]
Vervoordeldonk MJBM, Aalbers CJ, Tak PP, Advances in local targeted gene therapy for arthritis: towards clinical reality.. FUTURE RHEUMATOL 2008;3 (4):307-309
Key publications

Vervoordeldonk MJBM, Aalbers CJ, Tak PP, Advances in local targeted gene therapy for arthritis: towards clinical reality.. FUTURE RHEUMATOL 2008;3 (4):307-309
Vervoordeldonk MJ, Aalbers CJ, Tak PP, Interferon beta for rheumatoid arthritis: new clothes for an old kid on the block. ANN RHEUM DIS 2009;68 (2):157-158 [PubMed]


All Publications

Research programmes
Other research related activities
  • None reported
Current research funding
  • None reported