• Female

Dr. ir. M.T. Ackermans

Position:
Main activities: Patient care, Research
Specialisation:
foto
Focus of research:

Development of chromatographic methods for the analysis of hormones for patient care

Development of stable isotope methods for metabolic studies

 

AMC themes: Other research
Departments: Clinical Chemistry: Laboratory for Endocrinology
Boelen A, van der Spek AH, Bloise F, de Vries EM, Surovtseva OV, van Beeren M, Ackermans MT, Kwakkel J, Fliers E, Tissue thyroid hormone metabolism is differentially regulated during illness in mice. J ENDOCRINOL 2017;233 (1):25-36 [PubMed]
Diepenbroek C, Eggels L, Ackermans MT, Fliers E, Kalsbeek A, Serlie MJ, la Fleur SE, Differential effects of hypercaloric choice diets on insulin sensitivity in rats. J ENDOCRINOL 2017;232 (1):49-57 [PubMed]
Diepenbroek C, Rijnsburger M, Eggels L, van Megen KM, Ackermans MT, Fliers E, Kalsbeek A, Serlie MJ, La Fleur SE, Infusion of fluoxetine, a serotonin reuptake inhibitor, in the shell region of the nucleus accumbens increases blood glucose concentrations in rats. NEUROSCI LETT 2017;637:85-90 [PubMed]
Kootte RS, Levin E , Salojärvi J, Smits LP, Hartstra AV, Udayappan SD, Hermes G, Bouter KE, Koopen AM, Holst JJ, Knop FK, Blaak EE, Zhao J, Smidt H, Harms AC, Hankemeijer T, Bergman JJGHM, Romijn HA, Schaap FG, Olde Damink SWM, Ackermans MT, Dallinga-Thie GM, Zoetendal E, de Vos WM, Serlie MJ, Stroes ESG, Groen AK, Nieuwdorp M, Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition. CELL METAB 2017;26 (4):611-+ [PubMed]
Rijnsburger M, Eggels L, Castel J, Cruciani-Guglielmacci C, Ackermans MT, Luquet S, La Fleur SE, A novel, double intra-carotid cannulation technique to study the effect of central nutrient sensing on glucose metabolism in the rat. J NEUROSCI METH 2017;290:79-84 [PubMed]
ter Horst KW, Gilijamse PW, Demirkiran A, van Wagensveld BA, Ackermans MT, Verheij J, Romijn JA, Nieuwdorp M, Maratos-Flier E, Herman MA, Serlie MJ, The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans. MOL METAB 2017;6 (11):1493-1502 [PubMed]
ter Horst KW, Gilijamse PW, Versteeg RI, Ackermans MT, Nederveen AJ, la Fleur SE, Romijn JA, Nieuwdorp M, Zhang D, Samuel VT, Vatner DF, Petersen KF, Shulman GI, Serlie MJ, Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans. CELL REP 2017;19 (10):1997-2004 [PubMed]
ter Horst KW, van Galen KA, Gilijamse PW, Hartstra AV, de Groot PF, van der Valk FM, Ackermans MT, Nieuwdorp M, Romijn JA, Serlie MJ, Methods for quantifying adipose tissue insulin resistance in overweight/obese humans. INT J OBESITY 2017;41 (8):1288-1294 [PubMed]
van Andel M, Drent ML, van Herwaarden AE, Ackermans MT, Heijboer AC, A method comparison of total and HMW adiponectin: HMW/total adiponectin ratio varies versus total adiponectin, independent of clinical condition. CLIN CHIM ACTA 2017;465:30-33 [PubMed]
van Stijn MFM, Soeters MR, van Leeuwen PAM, Schreurs WH, Schoorl MG, Twisk JWR, de Bandt JP, Bonnefont-Rousselot D, Cynober L, Ackermans MT, Serlie MJ, Houdijk APJ, Effects of a Carbohydrate-, Glutamine-, and Antioxidant-Enriched Oral Nutrition Supplement on Major Surgery-Induced Insulin Resistance: A Randomized Pilot Study. JPEN-PARENTER ENTER 2017;ahead of print [PubMed]
Versteeg RI, Ackermans MT, Nederveen AJ, Fliers E, Serlie MJ, La Fleur SE, Meal timing effects on insulin sensitivity and intrahepatic triglycerides during weight loss. INT J OBESITY 2017;ahead of print [PubMed]
Versteeg RI, Koopman KE, Booij J, Ackermans MT, Unmehopa UA, Fliers E, la Fleur SE, Serlie MJ, Serotonin Transporter Binding in the Diencephalon Is Reduced in Insulin-Resistant Obese Humans. NEUROENDOCRINOLOGY 2017;105 (2):141-149 [PubMed]
Bekkach Y, Heijboer AC, Endert E, Ackermans MT, Determination of urinary aldosterone using a plasma aldosterone 2D ID LC-MS/MS method. BIOANALYSIS 2016;8 (17):1765-1775 [PubMed]
Boelen A, Ruiter AFC, Claahsen-van der Grinten HL, Endert E, Ackermans MT, Determination of a steroid profile in heel prick blood using LC-MS/MS. BIOANALYSIS 2016;8 (5):375-384 [PubMed]
Büttler RM, Martens F, Ackermans MT, Davison AS, van Herwaarden AE, Kortz L, Krabbe JG, Lentjes EGW, Syme C, Webster R, Blankenstein MA, Heijboer AC, Comparison of eight routine unpublished LC-MS/MS methods for the simultaneous measurement of testosterone and androstenedione in serum. CLIN CHIM ACTA 2016;454:112-118 [PubMed]
Dirks NF, Martens F, Vanderschueren D, Billen J, Pauwels S, Ackermans MT, Endert E, Heijer Md, Blankenstein MA, Heijboer AC, Determination of human reference values for serum total 1,25-dihydroxyvitamin D using an extensively validated 2D ID-UPLC-MS/MS method. J STEROID BIOCHEM 2016;164:127-133 [PubMed]
Foppen E, Tan AAT, Ackermans MT, Fliers E, Kalsbeek A, Suprachiasmatic Nucleus Neuropeptides and Their Control of Endogenous Glucose Production. J NEUROENDOCRINOL 2016;ahead of print [PubMed]
Teeninga N, Guan Z, Stevens J, Kist-van Holthe JE, Ackermans MT, van der Heijden AJ, van Schaik RHN, van Gelder T, Nauta J, Population Pharmacokinetics of Prednisolone in Relation to Clinical Outcome in Children With Nephrotic Syndrome. THER DRUG MONIT 2016;38 (4):534-545 [PubMed]
ter Horst KW, Gilijamse PW, Ackermans MT, Soeters MR, Nieuwdorp M, Romijn JA, Serlie MJ, Impaired insulin action in the liver, but not in adipose tissue or muscle, is a distinct metabolic feature of impaired fasting glucose in obese humans. METABOLISM 2016;65 (5):757-763 [PubMed]
ter Horst KW, Versteeg RI, Gilijamse PW, Ackermans MT, Heijboer AC, Romijn JA, La Fleur SE, Trinko R, DiLeone RJ, Serlie MJ, The vitamin D metabolites 25(OH)D and 1,25(OH)2D are not related to either glucose metabolism or insulin action in obese women. DIABETES METAB 2016;42 (6):416-423 [PubMed]
van der Zwaal EM, de Weijer BA, van de Giessen EM, Janssen I, Berends FJ, van de Laar A, Ackermans MT, Fliers E, la Fleur SE, Booij J, Serlie MJ, Striatal dopamine D-2/3 receptor availability increases after long-term bariatric surgery-induced weight loss. EUR NEUROPSYCHOPHARM 2016;26 (7):1190-1200 [PubMed]
Bosscher MRF, Wentholt IM, Ackermans MT, Nieveen van Dijkum EJM, An adrenal mass and increased catecholamines: monoamine oxidase or pheochromocytoma effect?. J CLIN MED RES 2015;7 (3):199-201 [PubMed]
Bruinstroop E, Eliveld J, Foppen E, Busker S, Ackermans MT, Fliers E, Kalsbeek A, Hepatic denervation and dyslipidemia in obese Zucker (fa/fa) rats. INT J OBESITY 2015;39 (11):1655-1658 [PubMed]
Büttler RM, Martens F, Kushnir MM, Ackermans MT, Blankenstein MA, Heijboer AC, Simultaneous measurement of testosterone, androstenedione and dehydroepiandrosterone (DHEA) in serum and plasma using Isotope-Dilution 2-Dimension Ultra High Performance Liquid-Chromatography Tandem Mass Spectrometry (ID-LC-MS/MS). CLIN CHIM ACTA 2015;438:157-159 [PubMed]
de Vries EM, van Beeren HC, Ackermans MT, Kalsbeek A, Fliers E, Boelen A, Differential effects of fasting vs food restriction on liver thyroid hormone metabolism in male rats. J ENDOCRINOL 2015;224 (1):25-35 [PubMed]
Schopman JE, Hoekstra JBL, Frier BM, Ackermans MT, de Sonnaville JJJ, Stades AM, Zwertbroek R, Hartmann B, Holst JJ, Knop FK, Holleman F, Effects of sitagliptin on counter-regulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double-blind placebo-controlled crossover study. DIABETES OBES METAB 2015;17 (6):546-553 [PubMed]
ter Horst KW, Gilijamse PW, de Weijer BA, Kilicarslan M, Ackermans MT, Nederveen AJ, Nieuwdorp M, Romijn JA, Serlie MJ, Sexual Dimorphism in Hepatic, Adipose Tissue, and Peripheral Tissue Insulin Sensitivity in Obese Humans. FRONT ENDOCRINOL 2015;6:182 [PubMed]
ter Horst KW, Gilijamse PW, Koopman KE, de Weijer BA, Brands M, Kootte RS, Romijn JA, Ackermans MT, Nieuwdorp M, Soeters MR, Serlie MJ, Insulin resistance in obesity can be reliably identified from fasting plasma insulin. INT J OBESITY 2015;39 (12):1703-1709 [PubMed]
Vrisekoop N, Drylewicz J, van Gent R, Mugwagwa T, van Lelyveld SFL, Veel E, Otto SA, Ackermans MT, Vermeulen JN, Huidekoper HH, Prins JM, Miedema F, de Boer RJ, Tesselaar K, Borghans JAM, Quantification of naive and memory T-cell turnover during HIV-1 infection. AIDS 2015;29 (16):2071-2080 [PubMed]
Ackermans MT, Endert E, LC-MS/MS in endocrinology: what is the profit of the last 5 years?. BIOANALYSIS 2014;6 (1):43-57 [PubMed]
de Vries EM, Eggels L, van Beeren HC, Ackermans MT, Kalsbeek A, Fliers E, Boelen A, Fasting-induced changes in hepatic thyroid hormone metabolism in male rats are independent of autonomic nervous input to the liver. ENDOCRINOLOGY 2014;155 (12):5033-5041 [PubMed]
de Weijer BA, van de Giessen E, Janssen I, Berends FJ, van de Laar A, Ackermans MT, Fliers E, la Fleur SE, Booij J, Serlie MJ, Striatal dopamine receptor binding in morbidly obese women before and after gastric bypass surgery and its relationship with insulin sensitivity. DIABETOLOGIA 2014;57 (5):1078-1080 [PubMed]
Girault EM, Guigas B, Alkemade A, Foppen E, Ackermans MT, la Fleur SE, Fliers E, Kalsbeek A, Chronic treatment with olanzapine increases adiposity by changing fuel substrate and causes desensitization of the acute metabolic side effects. N-S ARCH PHARMACOL 2014;387 (2):185-195 [PubMed]
Huidekoper HH, Ackermans MT, Ruiter AFC, Sauerwein HP, Wijburg FA, Endogenous glucose production from infancy to adulthood: a non-linear regression model. ARCH DIS CHILD 2014;99 (12):1098-1102 [PubMed]
Koopman KE, Caan MWA, Nederveen AJ, Pels A, Ackermans MT, Fliers E, la Fleur SE, Serlie MJ, Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: a randomized controlled trial. HEPATOLOGY 2014;60 (2):545-553 [PubMed]
Lammers NM, Sondermeijer BM, Twickler TBM, de Bie RM, Ackermans MT, Fliers E, Schuurman PR, la Fleur SE, Serlie MJ, Subthalamic nucleus stimulation does not influence basal glucose metabolism or insulin sensitivity in patients with Parkinson's disease. FRONT NEUROSCI-SWITZ 2014;8:95 [PubMed]
Schopman JE, Admiraal WM, Soeters MR, Ackermans MT, Bisschop PLHT, Frier BM, Hoekstra JBL, Romijn JA, Verberne HJ, Holleman F, (18)F-fluorodeoxyglucose uptake in brown adipose tissue during insulin-induced hypoglycemia and mild cold exposure in non-diabetic adults. METABOLISM 2014;63 (10):1280-1286 [PubMed]
van der Valk F, Hassing C, Visser M, Thakkar P, Mohanan A, Pathak K, Dutt C, Chauthaiwale V, Ackermans M, Nederveen A, Serlie M, Nieuwdorp M, Stroes E, The effect of a diiodothyronine mimetic on insulin sensitivity in male cardiometabolic patients: a double-blind randomized controlled trial. PLOS ONE 2014;9 (2):e86890 [PubMed]
Vrieze A , Out C, Fuentes S, Jonker L, Reuling I, Kootte RS, van Nood E, Holleman F, Knaapen M, Romijn JA, Soeters MR, Blaak EE, Dallinga-Thie GM, Reijnders D, Ackermans MT, Serlie MJ, Knop FK, Holst JJ, van der Ley C, Kema IP, Zoetendal EG, de Vos WM, Hoekstra JBL, Stroes ES, Groen AK, Nieuwdorp M, Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity. J HEPATOL 2014;60 (4):824-831 [PubMed]
Brands M, Sauerwein HP, Ackermans MT, Kersten S, Serlie MJ, Omega-3 long-chain fatty acids strongly induce angiopoietin-like 4 in humans. J LIPID RES 2013;54 (3):615-621 [PubMed]
Brands M, Swat M, Lammers NM, Sauerwein HP, Endert E, Ackermans MT, Verhoeven AJ, Serlie MJ, Effects of a hypercaloric diet on β-cell responsivity in lean healthy men. CLIN ENDOCRINOL 2013;78 (2):217-225 [PubMed]
Bruinstroop E, la Fleur SE, Ackermans MT, Foppen E, Wortel J, Kooijman S, Berbée JFP, Rensen PCN, Fliers E, Kalsbeek A, The autonomic nervous system regulates postprandial hepatic lipid metabolism. AM J PHYSIOL-ENDOC M 2013;304 (10):E1089-E1096 [PubMed]
de Weijer BA, Aarts E, Janssen IMC, Berends FJ, van de Laar A, Kaasjager K, Ackermans MT, Fliers E, Serlie MJ, Hepatic and peripheral insulin sensitivity do not improve 2 weeks after bariatric surgery. OBESITY 2013;21 (6):1143-1147 [PubMed]
Girault EM, Foppen E, Ackermans MT, Fliers E, Kalsbeek A, Central administration of an orexin receptor 1 antagonist prevents the stimulatory effect of Olanzapine on endogenous glucose production. BRAIN RES 2013;1527:238-245 [PubMed]
Girault EM, Toonen PW, Eggels L, Foppen E, Ackermans MT, la Fleur SE, Fliers E, Kalsbeek A, Olanzapine-induced changes in glucose metabolism are independent of the melanin-concentrating hormone system. PSYCHONEUROENDOCRINO 2013;38 (11):2640-2646 [PubMed]
Hoekstra R, Nibourg GAA, van der Hoeven TV, Plomer G, Seppen J, Ackermans MT, Camus S, Kulik W, van Gulik TM, Elferink RPO, Chamuleau RAFM, Phase 1 and phase 2 drug metabolism and bile acid production of HepaRG cells in a bioartificial liver in absence of dimethyl sulfoxide. DRUG METAB DISPOS 2013;41 (3):562-567 [PubMed]
Huidekoper HH, Ackermans MT, Koopman R, van Loon LJC, Sauerwein HP, Wijburg FA, Normal rates of whole-body fat oxidation and gluconeogenesis after overnight fasting and moderate-intensity exercise in patients with medium-chain acyl-CoA dehydrogenase deficiency. J INHERIT METAB DIS 2013;36 (5):831-840 [PubMed]
Liu J, Bisschop PH, Eggels L, Foppen E, Ackermans MT, Zhou JN, Fliers E, Kalsbeek A, Intrahypothalamic estradiol regulates glucose metabolism via the sympathetic nervous system in female rats. DIABETES 2013;62 (2):435-443 [PubMed]
Nibourg GAA, Hoekstra R, van der Hoeven TV, Ackermans MT, Hakvoort TBM, van Gulik TM, Chamuleau RAFM, Effects of acute-liver-failure-plasma exposure on hepatic functionality of HepaRG-AMC-bioartificial liver. LIVER INT 2013;33 (4):516-524 [PubMed]
Nibourg GAA, Hoekstra R, van der Hoeven TV, Ackermans MT, Hakvoort TBM, van Gulik TM, Chamuleau RAFM, Increased hepatic functionality of the human hepatoma cell line HepaRG cultured in the AMC bioreactor. INT J BIOCHEM CELL B 2013;45 (8):1860-1868 [PubMed]
Sondermeijer BM, Battjes S, van Dijk TH, Ackermans MT, Serlie MJ, Nieuwdorp M, Groen AK, Dallinga-Thie GM, Stroes ESG, Lactate increases hepatic secretion of VLDL-triglycerides in humans. ATHEROSCLEROSIS 2013;228 (2):443-450 [PubMed]
Teeninga N, Guan Z, Freijer J, Ruiter AFC, Ackermans MT, Kist-van Holthe JE, van Gelder T, Nauta J, Monitoring Prednisolone and Prednisone in Saliva: A Population Pharmacokinetic Approach in Healthy Volunteers. THER DRUG MONIT 2013;35 (4):485-492 [PubMed]
Westera L, Drylewicz J, den Braber I, Mugwagwa T, van der Maas I, Kwast L, Volman T, van de Weg-Schrijver EHR, Bartha I, Spierenburg G, Gaiser K, Ackermans MT, Asquith B, de Boer RJ, Tesselaar K, Borghans JAM, Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans. BLOOD 2013;122 (13):2205-2212 [PubMed]
Zijlmans WCWR, van Kempen AAMW, Tanck MWT, Ackermans MT, Jitan J, Sauerwein HP, Fasting Predisposes to Hypoglycemia in Surinamese Children with Severe Pneumonia, and Young Children are More at Risk. J TROP PEDIATRICS 2013;59 (2):106-112 [PubMed]
Zijlmans W, Jitan J, Ackermans MT, Serlie MJ, van Kempen AAMW, Sauerwein HP, Type of infectious disease affects glucose metabolism and liver glycogen content in Surinamese children: malaria vs. pneumonia. J PEDIATR ENDOCR MET 2013;26 (3-4):293-299 [PubMed]
Ackermans MT, Kettelarij-Haas Y, Boelen A, Endert E, Determination of thyroid hormones and their metabolites in tissue using SPE UPLC-tandem MS. BIOMED CHROMATOGR 2012;26 (4):485-490 [PubMed]
Bruinstroop E, Pei L, Ackermans MT, Foppen E, Borgers AJ, Kwakkel J, Alkemade A, Fliers E, Kalsbeek A, Hypothalamic Neuropeptide Y (NPY) Controls Hepatic VLDL-Triglyceride Secretion in Rats via the Sympathetic Nervous System. DIABETES 2012;61 (5):1043-1050 [PubMed]
den Braber I, Mugwagwa T, Vrisekoop N, Westera L, Mögling R, de Boer AB, Willems N, Schrijver EHR, Spierenburg G, Gaiser K, Mul E, Otto SA, Ruiter AFC, Ackermans MT, Miedema F, Borghans JAM, de Boer RJ, Tesselaar K, Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans. IMMUNITY 2012;36 (2):288-297 [PubMed]
Geukers VG, Li Z, Ackermans MT, Bos AP, Jinfeng L, Sauerwein HP, High-carbohydrate/low-protein-induced hyperinsulinemia does not improve protein balance in children after cardiac surgery. NUTRITION 2012;28 (6):644-650 [PubMed]
Girault EM, Alkemade A, Foppen E, Ackermans MT, Fliers E, Kalsbeek A, Acute Peripheral but Not Central Administration of Olanzapine Induces Hyperglycemia Associated with Hepatic and Extra-Hepatic Insulin Resistance. PLOS ONE 2012;7 (8):e43244 [PubMed]
Hoekstra R, Nibourg GAA, van der Hoeven TV, Ackermans MT, Hakvoort TBM, van Gulik TM, Oude Elferink RP, Chamuleau RAFM, The effect of rat acute-liver-failure plasma on HepaRG cells. INT J ARTIF ORGANS 2012;35 (11):1006-1014 [PubMed]
Nibourg GAA, Boer JD, van der Hoeven TV, Ackermans MT, van Gulik TM, Chamuleau RAFM, Hoekstra R, Perfusion flow rate substantially contributes to the performance of the HepaRG-AMC-bioartificial liver. BIOTECHNOL BIOENG 2012;109 (12):3182-3188 [PubMed]
Ruiter AFC, Teeninga N, Nauta J, Endert E, Ackermans MT, Determination of unbound prednisolone, prednisone and cortisol in human serum and saliva by on-line solid-phase extraction liquid chromatography tandem mass spectrometry and potential implications for drug monitoring of prednisolone and prednisone in saliva. BIOMED CHROMATOGR 2012;26 (7):789-796 [PubMed]
Soeters MR, Serlie MJ, Sauerwein HP, Duran M, Ruiter JP, Kulik W, Ackermans MT, Minkler PE, Hoppel CL, Wanders RJA, Houten SM, Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-induced metabolite. METABOLISM 2012;61 (7):966-973 [PubMed]
van Beeren HC, Kwakkel J, Ackermans MT, Wiersinga WM, Fliers E, Boelen A, Action of Specific Thyroid Hormone Receptor alpha(1) and beta(1) Antagonists in the Central and Peripheral Regulation of Thyroid Hormone Metabolism in the Rat. THYROID 2012;22 (12):1275-1282 [PubMed]
Vrieze A , van Nood E, Holleman F, Salojärvi J, Kootte RS, Bartelsman JFWM, Dallinga-Thie GM, Ackermans MT, Serlie MJ, Oozeer R, Derrien M, Druesne A, van Hylckama Vlieg JET, Bloks VW, Groen AK, Heilig HGHJ, Zoetendal EG, Stroes ES, de Vos WM, Hoekstra JBL, Nieuwdorp M, Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome. GASTROENTEROLOGY 2012;143 (4):913-+ [PubMed]
Ackermans MT, Endert E. De endocriene pancreas: insuline en bloedsuiker in: Schellekens APM, editor. Endocrinologie voor analisten. Utrecht: Syntax Media; 2011. Hoofdstuk 13, p. 219-232
Brands M, Hoeks J, Sauerwein HP, Ackermans MT, Ouwens M, Lammers NM, van der Plas MN, Schrauwen P, Groen AK, Serlie MJ, Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men. METABOLISM 2011;60 (10):1398-1405 [PubMed]
Franssen FME, Sauerwein HP, Ackermans MT, Rutten EPA, Wouters EFM, Schols AMWJ, Increased postabsorptive and exercise-induced whole-body glucose production in patients with chronic obstructive pulmonary disease. METABOLISM 2011;60 (7):957-964 [PubMed]
Hoekstra R, Nibourg GAA, van der Hoeven TV, Ackermans MT, Hakvoort TBM, van Gulik TM, Lamers WH, Elferink RPO, Chamuleau RAFM, The HepaRG cell line is suitable for bioartificial liver application. INT J BIOCHEM CELL B 2011;43 (10):1483-1489 [PubMed]
Klieverik LP, Kalsbeek A, Ackermans MT, Sauerwein HP, Wiersinga WM, Fliers E, Energy Homeostasis and Body Weight before and after Cessation of Block and Replacement Therapy in Euthyroid Patients with Graves' Disease. INT J ENDOCRINOL 2011;2011:715370 [PubMed]
Koopmans SJ, Dekker R, Ackermans MT, Sauerwein HP, Serlie MJ, van Beusekom HMM, van den Heuvel M, van der Giessen WJ, Dietary saturated fat/cholesterol, but not unsaturated fat or starch, induces C-reactive protein associated early atherosclerosis and ectopic fat deposition in diabetic pigs. CARDIOVASC DIABETOL 2011;10:64 [PubMed]
van der Crabben SN, Stegenga ME, Blümer RME, Ackermans MT, Endert E, Tanck MWT, Serlie MJ, van der Poll T, Sauerwein HP, Erythrocyte glutathione concentration and production during hyperinsulinemia, hyperglycemia, and endotoxemia in healthy humans. METABOLISM 2011;60 (1):99-106 [PubMed]
van Raalte DH, Brands M, van der Zijl NJ, Muskiet MH, Pouwels PJW, Ackermans MT, Sauerwein HP, Serlie MJ, Diamant M, Low-dose glucocorticoid treatment affects multiple aspects of intermediary metabolism in healthy humans: a randomised controlled trial. DIABETOLOGIA 2011;54 (8):2103-2112 [PubMed]
Visser ME, Lammers NM, Nederveen AJ, van der Graaf M, Heerschap A, Ackermans MT, Sauerwein HP, Stroes ES, Serlie MJ, Hepatic steatosis does not cause insulin resistance in people with familial hypobetalipoproteinaemia. DIABETOLOGIA 2011;54 (8):2113-2121 [PubMed]
Ackermans MT, Klieverik LP, Ringeling P, Endert E, Kalsbeek A, Fliers E, An online Solid-Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry method to study the presence of thyronamines in plasma and tissue and their putative conversion from 13C6-thyroxine. J ENDOCRINOL 2010;206 (3):327-334 [PubMed]
Huidekoper HH, Visser G, Ackermans MT, Sauerwein HP, Wijburg FA, A potential role for muscle in glucose homeostasis: in vivo kinetic studies in glycogen storage disease type 1a and fructose-1,6-bisphosphatase deficiency. J INHERIT METAB DIS 2010;33 (1):25-31 [PubMed]
Soeters MR, Huidekoper HH, Duran M, Ackermans MT, Endert E, Fliers E, Wijburg FA, Wanders RJ, Sauerwein HP, Serlie MJ, Extended metabolic evaluation of suspected symptomatic hypoglycemia: the prolonged fast and beyond. METABOLISM 2010;59 (11):1543-1550 [PubMed]
van Vonderen MGA, Blümer RME, Hassink EAM, Sutinen J, Ackermans MT, van Agtmael MA, Yki-Jarvinen H, Danner SA, Serlie MJ, Sauerwein HP, Reiss P, Insulin Sensitivity in Multiple Pathways Is Differently Affected During Zidovudine/Lamivudine-Containing Compared With NRTI-Sparing Combination Antiretroviral Therapy. JAIDS-J ACQ IMM DEF 2010;53 (2):186-193 [PubMed]
Yi CX, Sun N, Ackermans MT, Alkemade A, Foppen E, Shi J, Serlie MJ, Buijs RM, Fliers E, Kalsbeek A, Pituitary Adenylate Cyclase-Activating Polypeptide Stimulates Glucose Production via the Hepatic Sympathetic Innervation in Rats. DIABETES 2010;59 (7):1591-1600 [PubMed]
Blümer RME, van der Valk M, Ackermans M, Endert E, Serlie MJ, Reiss P, Sauerwein HP, A rosiglitazone-induced increase in adiponectin does not improve glucose metabolism in HIV-infected patients with overt lipoatrophy. AM J PHYSIOL-ENDOC M 2009;297 (5):E1097-E1104 [PubMed]
Franssen R, Sankatsing RR, Hassink E, Hutten B, Ackermans MT, Brinkman K, Oesterholt R, Arenas-Pinto A, Storfer SP, Kastelein JJ, Sauerwein HP, Reiss P, Stroes ES, Nevirapine Increases High-Density Lipoprotein Cholesterol Concentration by Stimulation of Apolipoprotein A-I Production. ARTERIOSCL THROM VAS 2009;29 (9):1336-1341 [PubMed]
Klieverik LP. Thyroid hormone, metabolism and the brain. s.l.: s.n.; 2009. 139p. ISBN 9789090245416 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Fliers E, Sauerwein HP; copromotor(s): Kalsbeek A, Ackermans MT)
Klieverik LP, Foppen E, Ackermans MT, Serlie MJ, Sauerwein HP, Scanlan TS, Grandy DK, Fliers E, Kalsbeek A, Central effects of thyronamines on glucose metabolism in rats. J ENDOCRINOL 2009;201 (3):377-386 [PubMed]
Klieverik LP, Janssen SF, van Riel A, Foppen E, Bisschop PH, Serlie MJ, Boelen A, Ackermans MT, Sauerwein HP, Fliers E, Kalsbeek A, Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver. P NATL ACAD SCI USA 2009;106 (14):5966-5971 [PubMed]
Kwakkel J, van Beeren HC, Ackermans MT, Platvoet-ter Schiphorst MC, Fliers E, Wiersinga WM, Boelen A, Skeletal muscle deiodinase type 2 regulation during illness in mice. J ENDOCRINOL 2009;203 (2):263-270 [PubMed]
Soeters MR, Lammers NM, Dubbelhuis PF, Ackermans MT, Jonkers-Schuitema CF, Fliers E, Sauerwein HP, Aerts JM, Serlie MJ, Intermittent fasting does not affect whole-body glucose, lipid, or protein metabolism. AM J CLIN NUTR 2009;90 (5):1244-1251 [PubMed]
Soeters MR, Sauerwein HP, Duran M, Wanders RJ, Ackermans MT, Fliers E, Houten SM, Serlie MJ, Muscle acylcarnitines during short-term fasting in lean healthy men. CLIN SCI 2009;116 (7):585-592 [PubMed]
Soeters MR, Sauerwein HP, Faas L, Smeenge M, Duran M, Wanders RJ, Ruiter AF, Ackermans MT, Fliers E, Houten SM, Serlie MJ, Effects of insulin on ketogenesis following fasting in lean and obese men. OBESITY 2009;17 (7):1326-1331 [PubMed]
van der Crabben SN, Blümer RME, Stegenga ME, Ackermans MT, Endert E, Tanck MWT, Serlie MJ, van der Poll T, Sauerwein HP, Early endotoxemia increases peripheral and hepatic insulin sensitivity in healthy humans. J CLIN ENDOCR METAB 2009;94 (2):463-468 [PubMed]
Yi CX, Serlie MJ, Ackermans MT, Foppen E, Buijs RM, Sauerwein HP, Fliers E, Kalsbeek A, A Major Role for Perifornical Orexin Neurons in the Control of Glucose Metabolism in Rats. DIABETES 2009;58 (9):1998-2005 [PubMed]
Ackermans MT, Klieverik LP, Endert E, Sauerwein HP, Kalsbeek A, Fliers E, Plasma insulin concentrations during a hyperinsulinaemic clamp: what do we measure?. ANN CLIN BIOCHEM 2008;45 (Part 4):429-430 [PubMed]
Blümer RME. Adiponectin in glucose metabolism. s.l.: s.n.; 2008. 197p. ISBN 9789090233758 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sauerwein HP; copromotor(s): Reiss P, Ackermans MT)
Blümer RME, van der Crabben SN, Stegenga ME, Tanck MW, Ackermans MT, Endert E, van der Poll T, Sauerwein HP, Hyperglycemia prevents the suppressive effect of hyperinsulinemia on plasma adiponectin levels in healthy humans. AM J PHYSIOL-ENDOC M 2008;295 (3):E613-E617 [PubMed]
Blümer RME, van Vonderen MGA, Sutinen J, Hassink E, Ackermans M, van Agtmael MA, Yki-Jarvinen H, Danner SA, Reiss P, Sauerwein HP, Zidovudine/lamivudine contributes to insulin resistance within 3 months of starting combination antiretroviral therapy. AIDS 2008;22 (2):227-236 [PubMed]
Huidekoper HH, Duran M, Turkenburg M, Ackermans MT, Sauerwein HP, Wijburg FA, Fasting adaptation in idiopathic ketotic hypoglycemia: a mismatch between glucose production and demand. EUR J PEDIATR 2008;167 (8):859-865 [PubMed]
Klieverik LP, Sauerwein HP, Ackermans MT, Boelen A, Kalsbeek A, Fliers E, Effects of thyrotoxicosis and selective hepatic autonomic denervation on hepatic glucose metabolism in rats. AM J PHYSIOL-ENDOC M 2008;294 (3):E513-E520 [PubMed]
Langeveld M, Ghauharali KJM, Sauerwein HP, Ackermans MT, Groener JEM, Hollak CEM, Aerts JM, Serlie MJ, Type I Gaucher disease, a glycosphingolipid storage disorder, is associated with insulin resistance. J CLIN ENDOCR METAB 2008;93 (3):845-851 [PubMed]
Soeters MR. The metabolic response to fasting in humans. Physiological studies. s.l.: s.n.; 2008. 172p. ISBN 9789081329811 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sauerwein HP; copromotor(s): Serlie MJ, Ackermans MT)
Soeters MR, Sauerwein HP, Dubbelhuis PF, Groener JE, Ackermans MT, Fliers E, Aerts JM, Serlie MJ, Muscle adaptation to short-term fasting in healthy lean humans. J CLIN ENDOCR METAB 2008;93 (7):2900-2903 [PubMed]
van der Crabben SN. Glucose deregulation in health and disease: on inflammation and glutathione. s.l.: s.n.; 2008. 128p. ISBN 9789090233574 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sauerwein HP, van der Poll T; copromotor(s): Serlie MJ, Ackermans MT)
van der Crabben SN, Allick G, Ackermans MT, Endert E, Romijn JA, Sauerwein HP, Prolonged fasting induces peripheral insulin resistance, which is not ameliorated by high-dose salicylate. J CLIN ENDOCR METAB 2008;93 (2):638-641 [PubMed]
van der Crabben SN, Wijburg FA, Ackermans MT, Sauerwein HP, Effect of cysteine dosage on erythrocyte glutathione synthesis rate in a patient with cystathionine beta synthase deficiency. J INHERIT METAB DIS 2008;31 (Supplement 3):469-475 [PubMed]
van Gent R, Kater AP, Otto SA, Jaspers A, Borghans JAM, Vrisekoop N, Ackermans MAT, Ruiter AFC, Wittebol S, Eldering E, van Oers MHJ, Tesselaar K, Kersten MJ, Miedema F, In vivo Dynamics of Stable Chronic Lymphocytic Leukemia Inversely Correlate with Somatic Hypermutation Levels and Suggest No Major Leukemic Turnover in Bone Marrow. CANCER RES 2008;68 (24):10137-10144 [PubMed]
van Nimwegen LJM, Storosum JG, Blumer RME, Allick G, Venema HW, de Haan L, Becker H, van Amelsvoort T, Ackermans MT, Fliers E, Serlie MJM, Sauerwein HP, Hepatic insulin resistance in antipsychotic naive schizophrenic patients: stable isotope studies of glucose metabolism. J CLIN ENDOCR METAB 2008;93 (2):572-577 [PubMed]
Vrisekoop N, den Braber I, de Boer AB, Ruiter AFC, Ackermans MT, van der Crabben SN, Schrijver EHR, Spierenburg G, Sauerwein HP, Hazenberg MD, de Boer RJ, Miedema F, Borghans JAM, Tesselaar K, Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool. P NATL ACAD SCI USA 2008;105 (16):6115-6120 [PubMed]
Zijlmans WCWR, van Kempen AAMW, Ackermans MT, de Metz J, Kager PA, Sauerwein HP, Very young children with uncomplicated falciparum malaria have higher risk of hypoglycaemia: a study from Suriname. TROP MED INT HEALTH 2008;13 (5):626-634 [PubMed]
Zijlmans W, van Kempen A, Ackermans M, de Metz J, Kager P, Sauerwein H, Glucose kinetics during fasting in young children with severe and non-severe malaria in Suriname. AM J TROP MED HYG 2008;79 (4):605-612 [PubMed]
Allick G. Free fatty acids and the regulation of glucose metabolis. Studies on physiological variations of free fatty acids. s.l.: s.n.; 2007. 119p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sauerwein H, Romijn JA; copromotor(s): Ackermans MT, Bisschop PHLT)
Birjmohun RS, Bisoendial RJ, van Leuven SI, Ackermans M, Zwinderman A, Kastelein JJP, Stroes ESG, Sauerwein HP, A single bolus infusion of C-reactive protein increases gluconeogenesis and plasma glucose concentration in humans. METABOLISM 2007;56 (11):1576-1582 [PubMed]
Bisschop PH, Klein S, Ackermans MT, Patterson BW, Endert E, van Lanschot JJB, Romijn JA, Sauerwein HP, Pre-operative nutritional status does not alter the metabolic response to major gastrointestinal surgery in patients with oesophageal cancer. BRIT J NUTR 2007;98 (1):181-186 [PubMed]
Serlie MJ, Allick G, Groener JE, Ackermans MT, Heijligenberg R, Voermans BC, Aerts JM, Meijer AJ, Sauerwein HP, Chronic treatment with pioglitazone does not protect obese patients with diabetes mellitus type II from free fatty acid-induced insulin resistance. J CLIN ENDOCR METAB 2007;92 (1):166-171 [PubMed]
Soeters MR, Sauerwein HP, Groener JE, Aerts JM, Ackermans MT, Glatz JFC, Fliers E, Serlie MJ, Gender-related differences in the metabolic response to fasting. J CLIN ENDOCR METAB 2007;92 (9):3646-3652 [PubMed]
Allick G, van der Crabben SN, Ackermans MT, Endert E, Sauerwein HP, Measurement of gluconeogenesis by deuterated water: the effect of equilibration time and fasting period. AM J PHYSIOL-ENDOC M 2006;290 (6):E1212-E1217 [PubMed]
Koopmans SJ, Mroz Z, Dekker R, Corbijn H, Ackermans M, Sauerwein H, Association of insulin resistance with hyperglycemia in streptozotocin-diabetic pigs: effects of metformin at isoenergetic feeding in a type 2-like diabetic pig model. METABOLISM 2006;55 (7):960-971 [PubMed]
van Kempen AAMW, van der Crabben SN, Ackermans MT, Endert E, Kok JH, Sauerwein HP, Stimulation of gluconeogenesis by intravenous lipids in preterm infants: response depends on fatty acid profile. AM J PHYSIOL-ENDOC M 2006;290 (4):E723-E730 [PubMed]
Geukers VGM, Oudshoorn JH, Taminiau JAJM, van der Ent CK, Schilte P, Ruiter AFC, Ackermans MT, Endert E, Jonkers-Schuitema CF, Heymans HSS, Sauerwein HP, Short-term protein intake and stimulation of protein synthesis in stunted children with cystic fibrosis. AM J CLIN NUTR 2005;81 (3):605-610 [PubMed]
Huidekoper HH, Bosch AM, van der Crabben SN, Sauerwein HP, Ackermans MT, Wijburg FA, Short-term exogenous galactose supplementation does not influence rate of appearance of galactose in patients with classical galactosemia. MOL GENET METAB 2005;84 (3):265-272 [PubMed]
Serlie MJM, de Haan JH, Tack CJ, Verberne HJ, Ackermans MT, Heerschap A, Sauerwein HP, Glycogen synthesis in human gastrocnemius muscle is not representative of whole-body muscle glycogen synthesis. DIABETES 2005;54 (5):1277-1282 [PubMed]
van Kempen AAMW, Ackermans MT, Endert E, Kok JH, Sauerwein HP, Glucose production in response to glucagon is comparable in preterm AGA and SGA infants. CLIN NUTR 2005;24 (5):727-736 [PubMed]
Allick G, Bisschop PH, Ackermans MT, Endert E, Meijer AJ, Kuipers F, Sauerwein HP, Romijn JA, A low-carbohydrate/high-fat diet improves glucoregulation in type 2 diabetes mellitus by reducing postabsorptive glycogenolysis. J CLIN ENDOCR METAB 2004;89 (12):6193-6197 [PubMed]
Allick G, Sprangers F, Weverling GJ, Ackermans MT, Meijer AJ, Romijn JA, Endert E, Bisschop PH, Sauerwein HP, Free fatty acids increase hepatic glycogen content in obese males. METABOLISM 2004;53 (7):886-893 [PubMed]
Buijs MM, Romijn JA, Burggraaf J, de Kam ML, Frölich M, Ackermans MT, Sauerwein HP, Cohen AF, Meinders AE, Pijl H, Glucose homeostasis in abdominal obesity: hepatic hyperresponsiveness to growth hormone action. AM J PHYSIOL-ENDOC M 2004;287 (1):E63-E68 [PubMed]
de Metz J, Romijn JA, Endert E, Ackermans MT, Weverling GJ, Busch OR, de Wit LT, Gouma DJ, ten Berge IJM, Sauerwein HP, Interferon-gamma increases monocyte HLA-DR expression without effects on glucose and fat metabolism in postoperative patients. J APPL PHYSIOL 2004;96 (2):597-603 [PubMed]
Sprangers F, Thien HV, Ackermans MT, Endert E, Sauerwein HP, Glycogenolysis during short-term fasting in malaria and healthy subjects - the potential regulatory role of glycogen content on glycogen breakdown: a hypothesis. CLIN NUTR 2004;23 (5):1051-1059 [PubMed]
van der Valk M, Allick G, Weverling GJ, Romijn JA, Ackermans MT, Lange JMA, van Eck-Smit BLF, van Kuijk C, Endert E, Sauerwein HP, Reiss P, Markedly diminished lipolysis and partial restoration of glucose metabolism, without changes in fat distribution after extended discontinuation of protease inhibitors in severe lipodystrophic human Immunodeficient virus-1-infected patients. J CLIN ENDOCR METAB 2004;89 (7):3554-3560 [PubMed]
van Kempen AAMW. Glyconeogenesis and glycogenolysis in newborn infants. S.l.: s.n.; 2004. 173p. ISBN 90-9018131-8 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sauerwein HP, Kok JH; copromotor(s): Ackermans MT)
van Thien H, Ackermans MT, Weverling GJ, Dang Vinh T, Endert E, Kager PA, Sauerwein HP, Gluconeogenesis and fasting in cerebral malaria. NETH J MED 2004;62 (4):129-133 [PubMed]
van Thien H, Ackermans MT, Weverling GJ, Thanh Chien VO, Endert E, Kager PA, Sauerwein HP, Influence of prolonged starvation on glucose kinetics in pregnant patients infected with Plasmodium falciparum. CLIN NUTR 2004;23 (1):59-67 [PubMed]
van Thien H, Weverling GJ, Ackermans MT, Hung NC, Endert E, Kager PA, Sauerwein HP, FFAs are not involved in regulation of gluconeogenesis and glycogenolysis in adults with uncomplicated P. falciparum malaria. AM J PHYSIOL-ENDOC M 2004;287 (4):E609-E615 [PubMed]
Beckers JL, Ackermans MT, Bocek P, Capillary zone electrophoresis in methanol: migration behavior and background electrolytes. ELECTROPHORESIS 2003;24 (10):1544-1552 [PubMed]
Prinsen BHCMT, Romijn JA, Bisschop PH, de Barse MMJ, Barrett PHR, Ackermans M, Berger R, Rabelink TJ, de Sain-van der Velden MGM, Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans. J LIPID RES 2003;44 (7):1341-1348 [PubMed]
van Kempen AAMW, Romijn JA, Ruiter AFC, Ackermans MT, Endert E, Hoekstra JH, Kok JH, Sauerwein HP, Adaptation of glucose production and gluconeogenesis to diminishing glucose infusion in preterm infants at varying gestational ages. PEDIATR RES 2003;53 (4):628-634 [PubMed]
Bisschop PH, Ackermans MT, Endert E, Ruiter AFC, Meijer AJ, Kuipers F, Sauerwein HP, Romijn JA, The effect of carbohydrate and fat variation in euenergetic diets on postabsorptive free fatty acid release. BRIT J NUTR 2002;87 (6):555-559 [PubMed]
Buijs MM, Burggraaf J, Langendonk JG, Schoemaker RC, Frölich M, Arndt JW, Cohen AF, Romijn JA, Ackermans MT, Sauerwein HP, Meinders AE, Pijl H, Hyposomatotropism blunts lipolysis in abdominally obese women. J CLIN ENDOCR METAB 2002;87 (8):3851-3858 [PubMed]
Sprangers F, Jellema WT, Lopuhaä CE, Endert E, Ackermans MT, van Lieshout JJ, van der Zee JS, Romijn JA, Sauerwein HP, Partial inhibition of nitric oxide synthesis in vivo does not inhibit glucose production in man. METABOLISM 2002;51 (1):57-64 [PubMed]
van der Valk M, Reiss P, van Leth FC, Ackermans MT, Endert E, Romijn JA, Heijligenberg R, Sauerwein H, Highly active antiretroviral therapy-induced lipodystrophy has minor effects on human immunodeficiency virus-induced changes in lipolysis, but normalizes resting energy expenditure. J CLIN ENDOCR METAB 2002;87 (11):5066-5071 [PubMed]
Ackermans MT, Pereira Arias AM, Bisschop PH, Endert E, Sauerwein HP, Romijn JA, The quantification of gluconeogenesis in healthy men by (2)H2O and [2-(13)C]glycerol yields different results: rates of gluconeogenesis in healthy men measured with (2)H2O are higher than those measured with [2-(13)C]glycerol. J CLIN ENDOCR METAB 2001;86 (5):2220-2226 [PubMed]
Arias AM, Bisschop PH, Ackermans MT, Nijpels G, Endert E, Romijn JA, Sauerwein HP, Aminophylline stimulates insulin secretion in patients with type 2 diabetes mellitus. METABOLISM 2001;50 (9):1030-1035 [PubMed]
Bisschop PH, de Metz J , Ackermans MT, Endert E, Pijl H, Kuipers F, Meijer AJ, Sauerwein HP, Romijn JA, Dietary fat content alters insulin-mediated glucose metabolism in healthy men. AM J CLIN NUTR 2001;73 (3):554-559 [PubMed]
Moeniralam HS, Sprangers F, Endert E, Ackermans MT, van Lanschot JJ, Sauerwein HP, Romijn JA, Role of nitric oxide in the regulation of glucose kinetics in response to endotoxin in dogs. J APPL PHYSIOL 2001;91 (1):130-136 [PubMed]
Pereira Arias AM, Bisschop PH, Ackermans MT, Endert E, Romijn JA, Sauerwein HP, Indomethacin does not affect endogenous glucose production in type 2 diabetes mellitus. HORM METAB RES 2001;33 (11):659-663 [PubMed]
Ruiter AF, Ackermans MT, Endert E, Simultaneous gas chromatographic determination of concentration and isotopic enrichment of fatty acids in human plasma using flame ionization and mass spectrometric detection. J CHROMATOGR B BIOMED SCI APPL 2001;759 (1):169-174 [PubMed]
Sprangers F, Romijn JA, Endert E, Ackermans MT, Sauerwein HP, The role of free fatty acids (FFA) in the regulation of intrahepatic fluxes of glucose and glycogen metabolism during short-term starvation in healthy volunteers. CLIN NUTR 2001;20 (2):177-179 [PubMed]
Sprangers F, Wijburg FA, Romijn JA, Ackermans MT, Hoekstra JH, Heymans HS, Sauerwein HP, Subnormal response of plasma glucose concentration to glucagon despite adequate glycogenolysis: the importance of kinetic measurements. EUR J PEDIATR 2001;160 (3):185-188 [PubMed]
van der Valk M, Bisschop PH, Romijn JA, Ackermans MT, Lange JM, Endert E, Reiss P, Sauerwein HP, Lipodystrophy in HIV-1-positive patients is associated with insulin resistance in multiple metabolic pathways. AIDS 2001;15 (16):2093-2100 [PubMed]
van Thien H, Ackermans MT, Dekker E, Thanh Chien VO, Le T, Endert E, Kager PA, Romijn JA, Sauerwein HP, Glucose production and gluconeogenesis in adults with cerebral malaria. QJM-INT J MED 2001;94 (12):709-715 [PubMed]
Bisschop PH, Pereira Arias AM, Ackermans MT, Endert E, Pijl H, Kuipers F, Meijer AJ, Sauerwein HP, Romijn JA, The effects of carbohydrate variation in isocaloric diets on glycogenolysis and gluconeogenesis in healthy men. J CLIN ENDOCR METAB 2000;85 (5):1963-1967 [PubMed]
Pereira Arias AM, Romijn JA, Corssmit EP, Ackermans MT, Nijpels G, Endert E, Sauerwein HP, Indomethacin decreases insulin secretion in patients with type 2 diabetes mellitus. METABOLISM 2000;49 (7):839-844 [PubMed]
de Metz J , Sprangers F, Endert E, Ackermans MT, ten Berge IJ, Sauerwein HP, Romijn JA, Interferon-gamma has immunomodulatory effects with minor endocrine and metabolic effects in humans. J APPL PHYSIOL 1999;86 (2):517-522 [PubMed]
Ackermans MT, Ruiter AF, Endert E, Determination of glycerol concentrations and glycerol isotopic enrichments in human plasma by gas chromatography/mass spectrometry. ANAL BIOCHEM 1998;258 (1):80-86 [PubMed]
Dekker E, Romijn JA, van Thien H, Ackermans MT, Endert E, Kager PA, Thuy LT, Sauerwein HP, Indomethacin stimulates glucose production in adults with uncomplicated falciparum malaria. METABOLISM 1998;47 (2):217-222 [PubMed]
Heijligenberg R, Romijn JA, Ackermans M, Endert E, Timmer JG, Sauerwein HP, The maximal tolerable intravenous dosage of pentoxifylline in AIDS patients does not inhibit lipopolysaccharide-stimulated tumor necrosis factor alpha production. AIDS RES HUM RETROV 1998;14 (4):299-303 [PubMed]
Moeniralam HS, Endert E, Ackermans MT, van Lanschot JJ, Sauerwein HP, Romijn JA, The opiate sufentanil alters the inflammatory, endocrine, and metabolic responses to endotoxin in dogs. AM J PHYSIOL 1998;275 (3 Part 1):E440-E447 [PubMed]
Dekker E, Romijn JA, Ekberg K, Wahren J, van Thien H, Ackermans MT, Thuy LT, Chandramouli V, Kager PA, Landau BR, Sauerwein HP, Glucose production and gluconeogenesis in adults with uncomplicated falciparum malaria. AM J PHYSIOL 1997;272 (6 Part 1):E1059-E1064 [PubMed]
Dekker E, Romijn JA, Moeniralam HS, Waruiru C, Ackermans MT, Timmer JG, Endert E, Peshu N, Marsh K, Sauerwein HP, The influence of alanine infusion on glucose production in 'malnourished' African children with falciparum malaria. QJM-INT J MED 1997;90 (7):455-460 [PubMed]
Moeniralam HS, Bemelman WA, Romijn JA, Endert E, Ackermans MT, van Lanschot JJ, Hermsen RC, Sauerwein HP, Origin of endotoxemia influences the metabolic response to endotoxin in dogs. J SURG RES 1997;73 (1):47-53 [PubMed]
Corssmit EP, Heijligenberg R, Endert E, Ackermans MT, Sauerwein HP, Romijn JA, Endocrine and metabolic effects of interferon-alpha in humans. J CLIN ENDOCR METAB 1996;81 (9):3265-3269 [PubMed]
Dekker E, Romijn JA, Waruiru C, Ackermans MT, Weverling GJ, Sauerwein RW, Endert E, Peshu N, Marsh K, Sauerwein HP, The relationship between glucose production and plasma glucose concentration in children with falciparum malaria. T ROY SOC TROP MED H 1996;90 (6):654-657 [PubMed]
Heikens J, Fliers E, Endert E, Ackermans M, van Montfrans G, Liquorice-induced hypertension--a new understanding of an old disease: case report and brief review. NETH J MED 1995;47 (5):230-234 [PubMed]
Takkenberg B, Endert E, van Ingen HE, Ackermans M, Improved method for the determination of serotonin in plasma by high-performance liquid chromatography using on-line sample pre-treatment. J CHROMATOGR A 1991;565 (1-2):430-435 [PubMed]
Key publications

Ackermans MT, Klieverik LP, Ringeling P, Endert E, Kalsbeek A, Fliers E, An online Solid-Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry method to study the presence of thyronamines in plasma and tissue and their putative conversion from 13C6-thyroxine. J ENDOCRINOL 2010;206 (3):327-334 [PubMed]
Ackermans MT, Endert E, LC-MS/MS in endocrinology: what is the profit of the last 5 years?. BIOANALYSIS 2014;6 (1):43-57 [PubMed]
den Braber I, Mugwagwa T, Vrisekoop N, Westera L, Mögling R, de Boer AB, Willems N, Schrijver EHR, Spierenburg G, Gaiser K, Mul E, Otto SA, Ruiter AFC, Ackermans MT, Miedema F, Borghans JAM, de Boer RJ, Tesselaar K, Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans. IMMUNITY 2012;36 (2):288-297 [PubMed]
Vrieze A , van Nood E, Holleman F, Salojärvi J, Kootte RS, Bartelsman JFWM, Dallinga-Thie GM, Ackermans MT, Serlie MJ, Oozeer R, Derrien M, Druesne A, van Hylckama Vlieg JET, Bloks VW, Groen AK, Heilig HGHJ, Zoetendal EG, Stroes ES, de Vos WM, Hoekstra JBL, Nieuwdorp M, Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome. GASTROENTEROLOGY 2012;143 (4):913-+ [PubMed]
Yi CX, Sun N, Ackermans MT, Alkemade A, Foppen E, Shi J, Serlie MJ, Buijs RM, Fliers E, Kalsbeek A, Pituitary Adenylate Cyclase-Activating Polypeptide Stimulates Glucose Production via the Hepatic Sympathetic Innervation in Rats. DIABETES 2010;59 (7):1591-1600 [PubMed]


All Publications

Curriculum Vitae


2004-present: Senior Scientist, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Experience:
o Responsible for the analytical techniques used in various research projects of the Department of Endocrinology and Metabolism.
o Development of a number of new analytical methods (GC/MS, GC/C/IRMS, UPLC/MS, Gelfiltration, Solid Phase Extraction).
o Development and supervision of the chromatographic analyses used in patient care.

1992-2004: Post-doc, Laboratory of Endocrinology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Experience:
o Implementation of analytical techniques using stable isotopes in metabolic studies using GC-MS and GC/C/IRMS

1987-1992: PhD Department of Instrumental Analyses, Eindhoven University of Technology, Chemical Technology, Eindhoven, The Netherlands

Thesis:
Electrophoresis in open capillaries: some fundamental aspects

1982-1987: Education Chemical Technology, Eindhoven University of Technology, Chemical Engineering, Eindhoven, The Netherlands

1977-1982: Gymnasium, Scholengemeenschap Augustinianum, Eindhoven, The Netherlands
 

Research programmes
Other research related activities
  • None reported
Current research funding
  • Universiteit Maastricht