• Principal Investigator
  • Male

Prof. dr. E.T. van Bavel

Position:
Main activities: Research, Teaching
Specialisation:
foto E.T. van Bavel is one of the AMC Principal Investigators
Focus of research:

The research of my group is devoted to the control of tone and remodeling of blood vessels, with a special interest in the role of physical factors (blood pressure and blood flow) in these processes and the biomechanics of the vascular wall. Our scientific objectives range from unraveling of basic mechanisms to understanding pathogenesis and consequences of notably vascular cognitive impairment, hypertension, atherosclerosis, coronary artery disease and intracranial aneurysms. We use a wide variety of approaches. These include clinical imaging modalities (in collaboration with Radiology), in vivo approaches such as rodent intracranial window, hypertension and flow restriction models, perfused arteries and arterioles of human and animal origin in organoid culture, cell-based experimental models, molecular techniques, and mathematical modeling and simulation. My group aims to combine biophysical and functional experiments with analysis of molecular parameters. Our philosophy is to perform integrative science and utilize a systems approach in order to correlate molecular mechanisms with structure and function of blood vessels and vascular networks in health and disease.

AMC themes: Cardiovascular Diseases
Departments: Biomedical Engineering and Physics
Bedussi B, Naessens DMP, de Vos J, Olde Engberink R, Wilhelmus MMM, Richard E, ten Hove M, VanBavel E, Bakker ENTP, Enhanced interstitial fluid drainage in the hippocampus of spontaneously hypertensive rats. SCI REP-UK 2017;7 (1):744 [PubMed]
Bedussi B, van der Wel NN, de Vos J, van Veen H, Siebes M, VanBavel E, Bakker EN, Paravascular channels, cisterns, and the subarachnoid space in the rat brain: A single compartment with preferential pathways. J CEREBR BLOOD F MET 2017;37 (4):1374-1385 [PubMed]
Di Russo J, Luik AL, Yousif L, Budny S, Oberleithner H, Hofschröer V, Klingauf J, van Bavel E, Bakker EN, Hellstrand P, Bhattachariya A, Albinsson S, Pincet F, Hallmann R, Sorokin LM, Endothelial basement membrane laminin 511 is essential for shear stress response. EMBO J 2017;36 (2):183-201 [PubMed]
Elattar MA, van Kesteren F, Wiegerinck EM, VanBavel E, Baan J, Cocchieri R , de Mol B, Planken NR, Marquering HA, Automated CTA based measurements for planning support of minimally invasive aortic valve replacement surgery. MED ENG PHYS 2017;39:123-128 [PubMed]
Rippe C, Zhu B, Krawczyk KK, van Bavel E, Albinsson S, Sjölund J, Bakker ENTP, Swärd K, Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway. SCI REP-UK 2017;7 (1):1334 [PubMed]
Schwarz JCV, van Lier MGJTB, Bakker ENTP, de Vos J, Spaan JAE, VanBavel E, Siebes M, Optimization of Vascular Casting for Three-Dimensional Fluorescence Cryo-Imaging of Collateral Vessels in the Ischemic Rat Hindlimb. MICROSC MICROANAL 2017;23 (1):77-87 [PubMed]
Borst J. CT imaging in acute stroke ischemic stroke. S.l.: s.n.; 2016. 201p. ISBN 978-94-6299-413-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Majoie CBLM, van Bavel ET; copromotor(s): Marquering HA , Roos YBWEM)
Cibis M, Potters WV, Gijsen FJ, Marquering H, van Ooij P, VanBavel E, Wentzel JJ, Nederveen AJ, The Effect of Spatial and Temporal Resolution of Cine Phase Contrast MRI on Wall Shear Stress and Oscillatory Shear Index Assessment. PLOS ONE 2016;11 (9):e0163316 [PubMed]
Elattar MA. Quantitative image analysis for planning of aortic valve replacement. S.l.: s.n.; 2016. 147p. ISBN 978-94-028-0356-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET; copromotor(s): Marquering HA , Baan J, Planken RN)
Elattar M, Wiegerinck E, van Kesteren F, Dubois L, Planken N, VanBavel E, Baan J, Marquering H, Automatic aortic root landmark detection in CTA images for preprocedural planning of transcatheter aortic valve implantation. INT J CARDIOVAS IMAG 2016;32 (3):501-511 [PubMed]
Heijtel DFR, Petersen ET, Mutsaerts HJMM, Bakker E, Schober P, Stevens MF, van Berckel BNM, Majoie CBLM, Booij J, van Osch MJP, van Bavel ET, Boellaard R, Lammertsma AA, Nederveen AJ, Quantitative agreement between [(15)O]H2O PET and model free QUASAR MRI-derived cerebral blood flow and arterial blood volume. NMR BIOMED 2016;29 (4):519-526 [PubMed]
Palao T, Rippe C, van Veen HA, VanBavel E, Sward K, Bakker EN, Thrombospondin-4 knockout in hypertension protects small-artery endothelial function but induces aortic aneurysms. AM J PHYSIOL-HEART C 2016;310 (11):H1486-H1493 [PubMed]
Reekers JA, Koelemay MJW, Marquering HA, van Bavel ET, Functional Imaging of the Foot with Perfusion Angiography in Critical Limb Ischemia. CARDIOVASC INTER RAD 2016;39 (2):183-189 [PubMed]
Taherzadeh Z, Karamat FA, Ankum WM, Clark JF, van Montfrans GA, van Bavel E, Brewster LM, The Effect of Creatine Kinase Inhibition on Contractile Properties of Human Resistance Arteries. AM J HYPERTENS 2016;29 (2):170-177 [PubMed]
van Horssen P, van Lier MGJTB, van den Wijngaard JPHM, VanBavel E, Hoefer IE, Spaan JAE, Siebes M, Influence of segmented vessel size due to limited imaging resolution on coronary hyperemic flow prediction from arterial crown volume. AM J PHYSIOL-HEART C 2016;310 (7):H839-H846 [PubMed]
van Lier MGJTB, Oost E, Spaan JAE, van Horssen P, van der Wal AC, VanBavel E, Siebes M, van den Wijngaard JPHM, Transmural distribution and connectivity of coronary collaterals within the human heart. CARDIOVASC PATHOL 2016;25 (5):405-412 [PubMed]
Bedussi B, van Lier MGJTB, Bartstra JW, de Vos J, Siebes M, VanBavel E, Bakker ENTP, Clearance from the mouse brain by convection of interstitial fluid towards the ventricular system. FLUIDS BARRIERS CNS 2015;12 (1):23 [PubMed]
Borst J, Berkhemer OA, Roos YBWEM, van Bavel E, van Zwam WH, van Oostenbrugge RJ, van Walderveen MAA, Lingsma HF, van der Lugt A, Dippel DWJ, Yoo AJ, Marquering HA, Majoie CBLM [Contributors: Fransen PSS, Beumer D, van den Berg LA, Schonewille WJ, Vos JA, Nederkoorn PJ, Wermer MJH, Staals J, Hofmeijer J, van Oostayen JA, Lycklama à Nijeholt GJ, Boiten J, Brouwer PA, Emmer BJ, de Bruijn SF, van Dijk LC, Kappelle LJ, Lo RH, van Dijk EJ, de Vries J, de Kort PLM, van den Berg JSP, van Hasselt BAAM, Aerden LAM, Dallinga RJ, Visser MC, Bot JCJ, Vroomen PC, Eshghi O, Schreuder THCML, Heijboer RJJ, Keizer K, Tielbeek AV, den Hertog HM, Gerrits DG, van den Berg-Vos RM, Karas GB, Steyerberg EW, Flach HZ, Sprengers MES, Jenniskens SFM, Beenen LFM , van den Berg R, Koudstaal PJ, Brown MM, Liebig T, Stijnen T, Andersson T, Mattle H, Wahlgren N, van der Heijden E, Ghannouti N, Fleitour N, Hooijenga I, Puppels C, Pellikaan W, Geerling A, Lindl-Velema A, van Vemde G, de Ridder A, Greebe P, de Bont-Stikkelbroeck J, de Meris J, Janssen K, Struijk W, Simons T, Messchendorp G, van der Minne F, Bongenaar H, Licher S, Boodt N, Ros A, Venema E, Slokkers I, Ganpat RJ, Mulder M, Saiedie N, Heshmatollah A, Schipperen S, Vinken S, van Boxtel T, Koets J, Boers M, Santos E, Jansen I, Kappelhof M, Lucas M, Geuskens R, Barros RS, Dobbe R, Csizmadia M]] , Value of Computed Tomographic Perfusion-Based Patient Selection for Intra-Arterial Acute Ischemic Stroke Treatment. STROKE 2015;46 (12):3375-3382 [PubMed]
Cornelissen BMW, Schneiders JJ, Potters WV, van den Berg R, Velthuis BK, Rinkel GJE, Slump CH, VanBavel E, Majoie CBLM, Marquering HA, Hemodynamic Differences in Intracranial Aneurysms before and after Rupture. AM J NEURORADIOL 2015;36 (10):1927-1933 [PubMed]
Elattar M, van Kesteren F, Wiegerinck E, van Bavel E, Baan J, Cocchieri R , Planken N, Marquering H, Automatic Planning of Minimally Invasive Aortic Valve Replacement Surgery. LECT NOTES COMPUT SC 2015;9164:536-540
Fahmi F. CT perfusion for acute ischemic stroke: Vendor-specific summary maps, motion correction and application of time invariant CTA. S.l.: s.n.; 2015. 140p. ISBN 978-94-6259-721-1 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET, Majoie CBLM; copromotor(s): Streekstra GJ, Marquering HA)
Feliciani G, Potters WV, van Ooij P, Schneiders JJ, Nederveen AJ, van Bavel E, Majoie CB, Marquering HA, Multiscale 3-D + t Intracranial Aneurysmal Flow Vortex Detection. IEEE T BIO-MED ENG 2015;62 (5):1355-1362 [PubMed]
Guvenc Tuna B, Lachkar N, de Vos J, Bakker ENTP, VanBavel E, Cerebral Artery Remodeling in Rodent Models of Subarachnoid Hemorrhage. J VASC RES 2015;52 (2):103-115 [PubMed]
Pabittei DR, Heger M, Simonet M, van Tuijl S, van der Wal AC, van Bavel ET, Laser-assisted vascular welding: optimization of acute and post-hydration welding strength. J CLIN TRANSL RES 2015;1:31-47
Palao T, Swärd K, Jongejan A, Moerland PD, de Vos J, van Weert A, Arribas SM, Groma G, VanBavel E, Bakker ENTP, Gene Expression and MicroRNA Expression Analysis in Small Arteries of Spontaneously Hypertensive Rats. Evidence for ER Stress. PLOS ONE 2015;10 (9):e0137027 [PubMed]
Potters WV. Wall shear stress calculations using phase contrast MRI. S.l.: s.n.; 2015. 169p. ISBN 978-94-6259-907-9 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET; copromotor(s): Nederveen AJ, Marquering HA , Wentzel JJ)
Potters WV, van Ooij P, Marquering H, VanBavel E, Nederveen AJ, Volumetric Arterial Wall Shear Stress Calculation Based on Cine Phase Contrast MRI. J MAGN RESON IMAGING 2015;41 (2):505-516 [PubMed]
Schneiders JJ, Marquering HA , van Ooij P, van den Berg R, Nederveen AJ, Verbaan D, Vandertop WP, Pourquie M, Rinkel GJE, VanBavel E, Majoie CBLM, Additional Value of Intra-Aneurysmal Hemodynamics in Discriminating Ruptured versus Unruptured Intracranial Aneurysms. AM J NEURORADIOL 2015;36 (10):1920-1926 [PubMed]
Schwarz JCV, Duivenvoorden R, Nederveen AJ, Stroes ESG, VanBavel E, Endothelial shear stress estimation in the human carotid artery based on Womersley versus Poiseuille flow. INT J CARDIOVAS IMAG 2015;31 (3):585-593 [PubMed]
Bakker ENTP, Groma G, Spijkers LJA, de Vos J, van Weert A, van Veen H, Everts V, Arribas SM, VanBavel E, Heterogeneity in arterial remodeling among sublines of spontaneously hypertensive rats. PLOS ONE 2014;9 (9):e107998 [PubMed]
Cibis M, Potters WV, Gijsen FJH, Marquering H, VanBavel E, van der Steen AFW, Nederveen AJ, Wentzel JJ, Wall shear stress calculations based on 3D cine phase contrast MRI and computational fluid dynamics: a comparison study in healthy carotid arteries. NMR BIOMED 2014;27 (7):826-834 [PubMed]
Coutinho JM, van den Berg R, Zuurbier SM, VanBavel E, Troost D, Majoie CB, Stam J, Small juxtacortical hemorrhages in cerebral venous thrombosis. ANN NEUROL 2014;75 (6):908-916 [PubMed]
Elattar MA, Wiegerinck EM, Planken RN, VanBavel E, van Assen HC, Baan J Jr, Marquering HA, Automatic segmentation of the aortic root in CT angiography of candidate patients for transcatheter aortic valve implantation. MED BIOL ENG COMPUT 2014;52 (7):611-618 [PubMed]
Elattar M, Wiegerinck E, Planken N, VanBavel E, van Assen H, Baan JJ, Marquering H, Automated Normalized Cut Segmentation of Aortic Root in CT Angiography. IFMBE PROC 2014;41:1821-1824
Fahmi F, Marquering HA, Borst J, Streekstra GJ, Beenen LFM , Niesten JM, Velthuis BK, Majoie CBL, VanBavel E, 3D movement correction of CT brain perfusion image data of patients with acute ischemic stroke. NEURORADIOLOGY 2014;56 (6):445-452 [PubMed]
Fahmi F, Marquering HA, Streekstra GJ, Beenen LFM , Janssen NNY, Majoie CBL, van Bavel E, Automatic Detection of CT Perfusion Datasets Unsuitable for Analysis due to Head Movement of Acute Ischemic Stroke Patients. J HEALTHC ENG 2014;5 (1):67-78 [PubMed]
Fahmi F, Riordan A, Beenen LFM, Streekstra GJ, Janssen NY, de Jong HW, Majoie CBL, van Bavel E, Marquering HA, The effect of head movement on CT perfusion summary maps: simulations with CT hybrid phantom data. MED BIOL ENG COMPUT 2014;52 (2):141-147 [PubMed]
Heijtel DFR. Validation and application of arterial spin labeling MRI for cerebral perfusion. S.l.: s.n.; 2014. 139p. ISBN 9789461824905 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET, Majoie CBLM; copromotor(s): Nederveen AJ, van Osch MJP)
Heijtel DFR, Mutsaerts HJMM, Bakker E, Schober P, Stevens MF, Petersen ET, van Berckel BNM, Majoie CBLM, Booij J, van Osch MJP, VanBavel E, Boellaard R, Lammertsma AA, Nederveen AJ, Accuracy and precision of pseudo-continuous arterial spin labeling perfusion during baseline and hypercapnia: a head-to-head comparison with ¹⁵O H₂O positron emission tomography. NEUROIMAGE 2014;92:182-192 [PubMed]
Jansen IGH, Schneiders JJ, Potters WV, van Ooij P, van den Berg R, van Bavel E, Marquering HA , Majoie CBLM, Generalized versus patient-specific inflow boundary conditions in computational fluid dynamics simulations of cerebral aneurysmal hemodynamics. AM J NEURORADIOL 2014;35 (8):1543-1548 [PubMed]
Potters WV, Marquering HA, VanBavel E, Nederveen AJ, Measuring wall shear stress using velocity-encoded MRI. CURR CARDIOVASC IMAGING REP 2014;7:9257
Schneiders JJ. Hemodynamics in intracranial aneurysms. s.l.: s.n.; 2014. 165p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET, Majoie CBLM; copromotor(s): Marquering HA , van den Berg R)
Schneiders JJ, Marquering HA , van den Berg R, VanBavel E, Velthuis B, Rinkel GJE, Majoie CB, Rupture-associated changes of cerebral aneurysm geometry: high-resolution 3D imaging before and after rupture. AM J NEURORADIOL 2014;35 (7):1358-1362 [PubMed]
Tuna BG. Smooth muscle cell function and organization of the resistance artery wall. s.l.: s.n.; 2014. 204p. ISBN 9789088918094 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET; copromotor(s): Bakker ENTP)
VanBavel E, Tuna BG, Integrative modeling of small artery structure and function uncovers critical parameters for diameter regulation. PLOS ONE 2014;9 (1):e86901 [PubMed]
van der Meer JN, Heijtel DFR, van Hest G, Plattèl GJ, van Osch MJP, van Someren EJW, Vanbavel ET, Nederveen AJ, Acoustic noise reduction in pseudo-continuous arterial spin labeling (pCASL). MAGN RESON MATER PHY 2014;27 (3):269-276 [PubMed]
del Campo L, Guvenc Tuna B, Ferrer M, van Bavel E, Bakker ENTP, Testosterone and β-oestradiol prevent inward remodelling of rat small mesenteric arteries: role of NO and transglutaminase. CLIN SCI 2013;124 (12):719-728 [PubMed]
Fahmi F, Beenen LFM, Streekstra GJ, Janssen NY, de Jong HW, Riordan A, Roos YB, Majoie CB, VanBavel E, Marquering HA, Head movement during CT brain perfusion acquisition of patients with suspected acute ischemic stroke. EUR J RADIOL 2013;82 (12):2334-2341 [PubMed]
Heijtel DFR, van Osch MJP, Caan MWA, Majoie CB, VanBavel E, Nederveen AJ, Feasibility of arterial spin labeling on a 1T open MRI scanner. J MAGN RESON IMAGING 2013;37 (4):958-964 [PubMed]
Huelsz-Prince G, Belkin AM, VanBavel E, Bakker ENTP, Activation of extracellular transglutaminase 2 by mechanical force in the arterial wall. J VASC RES 2013;50 (5):383-395 [PubMed]
Karpus ON, Veninga H, Hoek RM, Flierman D, van Buul JD, Vandenakker CC, VanBavel E, Medof ME, van Lier RAW, Reedquist KA, Hamann J, Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55. J IMMUNOL 2013;190 (7):3740-3748 [PubMed]
Schneiders JJ, Marquering HA , Antiga L, van den Berg R, VanBavel E, Majoie CB, Intracranial aneurysm neck size overestimation with 3D rotational angiography: the impact on intra-aneurysmal hemodynamics simulated with computational fluid dynamics. AM J NEURORADIOL 2013;34 (1):121-128 [PubMed]
Schneiders JJ, VanBavel E, Majoie CB, Ferns SP, van den Berg R, A flow-diverting stent is not a pressure-diverting stent. AM J NEURORADIOL 2013;34 (1):E1-E4 [PubMed]
Tokarczyk A, Rivens I, van Bavel E, Symonds-Tayler R, ter Haar G, An experimental system for the study of ultrasound exposure of isolated blood vessels. PHYS MED BIOL 2013;58 (7):2281-2304 [PubMed]
Tuna BG, Bakker ENTP, VanBavel E, Relation between active and passive biomechanics of small mesenteric arteries during remodeling. J BIOMECH 2013;46 (8):1420-1426 [PubMed]
Tuna BG, Schoorl MJC, Bakker ENTP, de Vos J, VanBavel E, Smooth muscle contractile plasticity in rat mesenteric small arteries: sensitivity to specific vasoconstrictors, distension and inflammatory cytokines. J VASC RES 2013;50 (3):249-262 [PubMed]
van den Berg R, Schneiders JJ, Ferns SP, Majoie CB, VanBavel E, Reply: Actual Metal Coverage at the Neck Is Critical for Flow-Diverting Stents in Treating Intracranial Aneurysms. AM J NEURORADIOL 2013;34 (3):E33 [PubMed]
van Ooij P, Guédon A, Marquering HA, Schneiders JJ, Majoie CB, van Bavel E, Nederveen AJ, k-t BLAST and SENSE accelerated time-resolved three-dimensional phase contrast MRI in an intracranial aneurysm. MAGN RESON MATER PHY 2013;26 (3):261-270 [PubMed]
van Ooij P, Potters WV, Guédon A, Schneiders JJ, Marquering HA, Majoie CB, VanBavel E, Nederveen AJ, Wall shear stress estimated with phase contrast MRI in an in vitro and in vivo intracranial aneurysm. J MAGN RESON IMAGING 2013;38 (4):876-884 [PubMed]
van Ooij P, Schneiders JJ, Marquering HA , Majoie CB, van Bavel E, Nederveen AJ, 3D cine phase-contrast MRI at 3T in intracranial aneurysms compared with patient-specific computational fluid dynamics. AM J NEURORADIOL 2013;34 (9):1785-1791 [PubMed]
van Ooij P, Zwanenburg JJM, Visser F, Majoie CB, VanBavel E, Hendrikse J, Nederveen AJ, Quantification and visualization of flow in the Circle of Willis: time-resolved three-dimensional phase contrast MRI at 7 T compared with 3 T. MAGN RESON MED 2013;69 (3):868-876 [PubMed]
Fahmi F, Marquering HA , Streekstra GJ, Beenen LFM, Velthuis BK, VanBavel E, Majoie CB, Differences in CT Perfusion Summary Maps for Patients with Acute Ischemic Stroke Generated by 2 Software Packages. AM J NEURORADIOL 2012;33 (11):2074-2080 [PubMed]
Guvenc Tuna B, Bakker ENTP, VanBavel E, Smooth Muscle Biomechanics and Plasticity: Relevance for Vascular Calibre and Remodelling. BASIC CLIN PHARMACOL 2012;110 (1):35-41 [PubMed]
Matlung HL, Neele AE, Groen HC, van Gaalen K, Guvenc Tuna B, van Weert A, de Vos J, Wentzel JJ, Hoogenboezem M, van Buul JD, VanBavel E, Bakker ENTP, Transglutaminase activity regulates atherosclerotic plaque composition at locations exposed to oscillatory shear stress. ATHEROSCLEROSIS 2012;224 (2):355-362 [PubMed]
Potters WV, van Ooij P, VanBavel E, Nederveen A, Vectorial wall shear stress calculations in vessel structures using 4D PC-MRI. J CARDIOVASC MAGN R 2012;14 (Suppl. 1):W5
Schneiders JJ, Ferns SP, van Ooij P, Siebes M, Nederveen AJ, van den Berg R, van Lieshout J, Jansen G, VanBavel E, Majoie CB, Comparison of Phase-Contrast MR Imaging and Endovascular Sonography for Intracranial Blood Flow Velocity Measurements. AM J NEURORADIOL 2012;33 (9):1786-1790 [PubMed]
van den Akker J, Guvenc Tuna B, Pistea A, Sleutel AJJ, Bakker ENTP, van Bavel E, Vascular smooth muscle cells remodel collagen matrices by long-distance action and anisotropic interaction. MED BIOL ENG COMPUT 2012;50 (7):701-715 [PubMed]
van den Akker J, van Weert A, Afink G, Bakker ENTP, van der Pol E, Böing AN, Nieuwland R, VanBavel E, Transglutaminase 2 is secreted from smooth muscle cells by transamidation-dependent microparticle formation. AMINO ACIDS 2012;42 (2-3):961-973 [PubMed]
van Ooij P. Phase contrast MRI in intracranial aneurysms. S.l.: s.n.; 2012. 214p. ISBN 978-90-8891-461-4 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET, Majoie CBLM; copromotor(s): Nederveen AJ)
van Ooij P, Guédon A, Poelma C, Schneiders J, Rutten MCM, Marquering HA , Majoie CB, VanBavel E, Nederveen AJ, Complex flow patterns in a real-size intracranial aneurysm phantom: phase contrast MRI compared with particle image velocimetry and computational fluid dynamics. NMR BIOMED 2012;25 (1):14-26 [PubMed]
van Ooij P, Potters WV, Majoie CB, VanBavel E, Nederveen A, Wall shear stress vectors derived from 3D PC-MRI at increasing resolutions in an intracranial aneurysm phantom. J CARDIOVASC MAGN R 2012;14 (Suppl. 1):W43
van Ooij P, Schneiders J, Marquering H, Majoie CB, VanBavel E, Nederveen A, 4D phase contrast MRI in intracranial aneurysms: a comparison with patient-specific computational fluid dynamics with temporal and spatial velocity boundary conditions as measured with 3D phase contrast MRI. J CARDIOVASC MAGN R 2012;14 (Suppl. 1):W3
van Ooij P, Zwanenburg JJ, Visser F, Majoie CB, VanBavel E, Hendrikse J, Nederveen A, Quantification and visualization of flow in small vessels of the Circle of Willis: time-resolved three-dimensional phase contrast MRI at 7T compared with 3T. J CARDIOVASC MAGN R 2012;14 (Suppl. 1):W42
Geers AJ, Larrabide I, Radaelli AG, Bogunovic H, Kim M, Gratama van Andel HAF, Majoie CB, VanBavel E, Frangi AF, Patient-Specific Computational Hemodynamics of Intracranial Aneurysms from 3D Rotational Angiography and CT Angiography: An In Vivo Reproducibility Study. AM J NEURORADIOL 2011;32 (3):581-586 [PubMed]
Marquering HA, van Ooij P, Streekstra GJ, Schneiders JJ, Majoie CB, VanBavel E, Nederveen AJ, Multiscale flow patterns within an intracranial aneurysm phantom. IEEE T BIO-MED ENG 2011;58 (12):3447-3450 [PubMed]
Matlung HL. Inflammation and transglutaminases in vascular remodeling and artherosclerosis. s.l.: s.n.; 2011. 170p. ISBN 9789053354070 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET, de Vries CJM; copromotor(s): Bakker ENTP)
Taherzadeh Z. Hypertension and resistance vessel function and structure. Role of ethnicity and inflammation. S.l.: s.n.; 2011. 143p. ISBN 9789064644467 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET; copromotor(s): Bakker ENTP, Brewster LM)
van den Akker HHOJ. Role of transglutaminase 2 in vascular remodeling. s.l.: s.n.; 2011. 185p. ISBN 9789053353899 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET; copromotor(s): Bakker ENTP)
van den Akker J, VanBavel E, van Geel R, Matlung HL, Guvenc Tuna B, Janssen GMC, van Veelen PA, Boelens WC, de Mey JGR, Bakker ENTP, The redox state of transglutaminase 2 controls arterial remodeling. PLOS ONE 2011;6 (8):e23067 [PubMed]
Brewster LM, Taherzadeh Z, Volger S, Clark JF, Rolf T, Wolf H, van Bavel E, van Montfrans GA, Ethnic differences in resistance artery contractility of normotensive pregnant women. AM J PHYSIOL-HEART C 2010;299 (2):H431-H436 [PubMed]
Duivenvoorden R, VanBavel E, de Groot E, Stroes ESG, Disselhorst JA, Hutten BA, Laméris JS, Kastelein JJP, Nederveen AJ, Endothelial shear stress: a critical determinant of arterial remodeling and arterial stiffness in humans--a carotid 3.0-T MRI study. CIRC-CARDIOVASC IMAG 2010;3 (5):578-585 [PubMed]
Ferns SP, Schneiders JJ, Siebes M, van den Berg R, van Bavel ET, Majoie CB, Intracranial Blood-Flow Velocity and Pressure Measurements Using an Intra-Arterial Dual-Sensor Guidewire. AM J NEURORADIOL 2010;31 (2):324-326 [PubMed]
Matlung HL, VanBavel E, van den Akker J, de Vries CJM, Bakker ENTP, Role of transglutaminases in cuff-induced atherosclerotic lesion formation in femoral arteries of ApoE3 Leiden mice. ATHEROSCLEROSIS 2010;213 (1):77-84 [PubMed]
Taherzadeh Z, Brewster LM, van Montfrans GA, VanBavel E, Function and Structure of Resistance Vessels in Black and White People. J CLIN HYPERTENS 2010;12 (6):431-438 [PubMed]
Taherzadeh Z, VanBavel E, de Vos J, Matlung HL, van Montfrans G, Brewster LM, Seghers L, Quax PHA, Bakker ENTP, Strain-dependent susceptibility for hypertension in mice resides in the natural killer gene complex. AM J PHYSIOL-HEART C 2010;298 (4):H1273-H1282 [PubMed]
van den Akker J, Schoorl MJC, Bakker ENTP, VanBavel E, Small Artery Remodeling: Current Concepts and Questions. J VASC RES 2010;47 (3):183-202 [PubMed]
Duivenvoorden R, de Groot E, Afzali H, Vanbavel ET, de Boer OJ, Laméris JS, Fayad ZA, Stroes ESG, Kastelein JJP, Nederveen AJ, Comparison of In Vivo Carotid 3.0-T Magnetic Resonance to B-Mode Ultrasound Imaging and Histology in a Porcine Model. JACC-CARDIOVASC IMAG 2009;2 (6):744-750 [PubMed]
Matlung HL, Bakker EN, VanBavel E, Shear Stress, Reactive Oxygen Species, and Arterial Structure and Function. ANTIOXID REDOX SIGN 2009;11 (7):1699-1709 [PubMed]
Matlung HL, Groen HC, de Vos J, van Walsum T, van der Lugt A, Niessen WJ, Wentzel JJ, VanBavel E, Bakker ENTP, Calcification Locates to Transglutaminases in Advanced Human Atherosclerotic Lesions. AM J PATHOL 2009;175 (4):1374-1379 [PubMed]
Bakker ENTP, Matlung HL, Bonta P, de Vries CJ, van Rooijen N, VanBavel E, Blood flow-dependent arterial remodelling is facilitated by inflammation but directed by vascular tone. CARDIOVASC RES 2008;78 (2):341-348 [PubMed]
Bakker ENTP, Pistea A, VanBavel E, Transglutaminases in vascular biology: relevance for vascular remodeling and atherosclerosis. J VASC RES 2008;45 (4):271-278 [PubMed]
Pistea A. Inward remodeling of small arteries - role of transglutaminases. s.l.: s.n.; 2008. 155p. ISBN 9789090227009 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Bavel ET; copromotor(s): Bakker NTP)
Pistea A, Bakker ENTP, Spaan JAE, Hardeman MR, van Rooijen N, VanBavel E, Small artery remodeling and erythrocyte deformability in L-NAME-induced hypertension: Role of transglutaminases. J VASC RES 2008;45 (1):10-18 [PubMed]
Sorop O, Merkus D, de Beer VJ, Houweling B, Pistea A, McFalls EO, Boomsma F, van Beusekom HM, van der Giessen WJ, VanBavel E, Duncker DJ, Functional and structural adaptations of coronary microvessels distal to a chronic coronary artery stenosis. CIRC RES 2008;102 (7):795-803 [PubMed]
VanBavel E, Bakker ENTP, A vascular bone collector: arterial calcification requires tissue-type transglutaminase. CIRC RES 2008;102 (5):507-509 [PubMed]
VanBavel E, van der Meulen ET, Spaan JAE, Vasomotion dynamics following calcium spiking depend on both cell signalling and limited constriction velocity in rat mesenteric small arteries. J CELL MOL MED 2008;12 (3):899-913 [PubMed]
van den Akker J, Pistea A, Bakker ENTP, VanBavel E, Decomposition cross-correlation for analysis of collagen matrix deformation by single smooth muscle cells. MED BIOL ENG COMPUT 2008;46 (5):443-450 [PubMed]
van den Akker J, Pistea A, Bakker ENTP, VanBavel E, Decomposition cross-correlation for analysis of collagen matrix deformation by single smooth muscle cells (vol 46, pg 443, 2008). MED BIOL ENG COMPUT 2008;46 (5):517
van den Wijngaard JPHM, van Gemert MJC, Lopriore E, Vandenbussche FPHA, Nikkels PGJ, VanBavel E, Case report: twin-to-twin transfusion syndrome resulting from placental collateral artery development. PLACENTA 2008;29 (2):220-223 [PubMed]
Dankelman J, Cornelissen AJM, Lagro J, VanBavel E, Spaan JAE, Relation between branching patterns and perfusion in stochastic generated coronary arterial trees. MED BIOL ENG COMPUT 2007;45 (1):25-34 [PubMed]
Lok CAR, Nieuwland R, Sturk A, Hau CM, Boer K, VanBavel E, Vanderpost JAM, Microparticle-associated P-selectin reflects platelet activation in preeclampsia. PLATELETS 2007;18 (1):68-72 [PubMed]
VanBavel E, Effects of shear stress on endothelial cells: possible relevance for ultrasound applications. PROG BIOPHYS MOL BIO 2007;93 (1-3):374-383 [PubMed]
Bakker ENTP, Pistea A, Spaan JAE, Rolf T, de Vries CJ, van Rooijen N, Candi E, VanBavel E, Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: possible compensation by macrophage-derived factor XIII. CIRC RES 2006;99 (1):86-92 [PubMed]
de Waard V, Arkenbout EK, Vos M, Mocking AIM, Niessen HWM, Stooker W, de Mol BAJM, Quax PHA, Bakker ENTP, VanBavel E, Pannekoek H, de Vries CJM, TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells. AM J PATHOL 2006;168 (6):2027-2035 [PubMed]
Lok CAR, Böing AN, Reitsma PH, van der Post JAM, van Bavel E, Boer K, Sturk A, Nieuwland R, Expression of inflammation-related genes in endothelial cells is not directly affected by microparticles from preeclamptic patients. J LAB CLIN MED 2006;147 (6):310-320 [PubMed]
Sorop O, Bakker ENTP, Pistea A, Spaan JAE, VanBavel E, Calcium channel blockade prevents pressure-dependent inward remodeling in isolated subendocardial resistance vessels. AM J PHYSIOL-HEART C 2006;291 (3):H1236-H1245 [PubMed]
VanBavel E, Bakker ENTP, Pistea A, Sorop O, Spaan JAE, Mechanics of microvascular remodeling. CLIN HEMORHEOL MICRO 2006;34 (1-2):35-41 [PubMed]
VanBavel E, Mulvany MJ, Integrins in hypertensive remodeling. HYPERTENSION 2006;47 (2):147-148 [PubMed]
Bakker ENTP, Buus CL, Spaan JAE, Perree J, Ganga A, Rolf TM, Sorop O, Bramsen LH, Mulvany MJ, VanBavel E, Small artery remodeling depends on tissue-type transglutaminase. CIRC RES 2005;96 (1):119-126 [PubMed]
Koop EA, Gebbink MFBG, Sweeney TE, Mathy MJ, Heijnen HFG, Spaan JAE, Voest EE, VanBavel E, Peters SLM, Impaired flow-induced dilation in mesenteric resistance arteries from receptor protein tyrosine phosphatase-mu-deficient mice. AM J PHYSIOL-HEART C 2005;288 (3):H1218-H1223 [PubMed]
Pistea A, Bakker ENTP, Spaan JAE, VanBavel E, Flow inhibits inward remodeling in cannulated porcine small coronary arteries. AM J PHYSIOL-HEART C 2005;289 (6):H2632-H2640 [PubMed]
Spaan JAE, ter Wee R, van Teeffelen JWGE, Streekstra G, Siebes M, Kolyva C, Vink H, Fokkema DS, VanBavel E, Visualisation of intramural coronary vasculature by an imaging cryomicrotome suggests compartmentalisation of myocardial perfusion areas. MED BIOL ENG COMPUT 2005;43 (4):431-435 [PubMed]
van Gemert MJC, Umur A, van den Wijngaard JPHM, VanBavel E, Vandenbussche FPHA, Nikkels PGJ, Increasing cardiac output and decreasing oxygenation sequence in pump twins of acardiac twin pregnancies. PHYS MED BIOL 2005;50 (3):N33-N42 [PubMed]
van Haaren PMA, VanBavel E, Vink H, Spaan JAE, Charge modification of the endothelial surface layer modulates the permeability barrier of isolated rat mesenteric small arteries. AM J PHYSIOL-HEART C 2005;289 (6):H2503-H2507 [PubMed]
Bakker ENTP, Buus CL, VanBavel E, Mulvany MJ, Activation of resistance arteries with endothelin-1: From vasoconstriction to functional adaptation and remodeling. J VASC RES 2004;41 (2):174-182 [PubMed]
Bakker ENTP, Sorop O, Spaan JAE, VanBavel E, Remodeling of resistance arteries in organoid culture is modulated by pressure and pressure pulsation and depends on vasomotion. AM J PHYSIOL-HEART C 2004;286 (6):H2052-H2056 [PubMed]
Fahner PJ, Idu MM, Legemate DA, VanBavel E, Borstlap J, Pfaffendorf M, van Marle J, van Gulik TM, Morphological and functional alterations in glycerol preserved rat aortic allografts. INT J ARTIF ORGANS 2004;27 (11):979-989 [PubMed]
Sorop OE. Mechanosensitivity of isolated coronary arterioles. S.l.: s.n.; 2004. 135p. ISBN 90 9017879-1 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Spaan JAE; copromotor(s): van Bavel ET)
Bakker ENTP, Versluis JP, Sipkema P, VanTeeffelen JWGE, Rolf TM, Spaan JAE, VanBavel E, Differential structural adaptation to haemodynamics along single rat cremaster arterioles. J PHYSIOL-LONDON 2003;548 (2):549-555 [PubMed]
Dekker LRC, van Bavel ET, Opthof T, Coronel R, Janse MJ, Monophasic action potentials and Ca2+ transients in ischaemically preconditioned rabbit ventricular muscle: effects of atp-sensitive K+ channel blockade. NETH HEART J 2003;11 (2):62-69
Perrée J, van Leeuwen TG, Kerindongo R, Spaan JAE, VanBavel E, Function and structure of pressurized and perfused porcine carotid arteries - Effects of in vitro balloon angioplasty. AM J PATHOL 2003;163 (5):1743-1750 [PubMed]
Sorop O, Spaan JAE, Sweeney TE, VanBavel E, Effect of steady versus oscillating flow on porcine coronary arterioles - Involvement of NO and superoxide anion. CIRC RES 2003;92 (12):1344-1351 [PubMed]
van Bavel E, Shear stress and intermediate-conductance calcium-activated potassium channels. CARDIOVASC RES 2003;60 (3):457-459 [PubMed]
VanBavel E, Siersma P, Spaan JAE, Elasticity of passive blood vessels: a new concept. AM J PHYSIOL-HEART C 2003;285 (5):H1986-H2000 [PubMed]
van Haaren PMA, VanBavel E, Vink H, Spaan JAE, Localization of the permeability barrier to solutes in isolated arteries by confocal microscopy. AM J PHYSIOL-HEART C 2003;285 (6):H2848-H2856 [PubMed]
van Wijk MJ. Vascular dysfunction in preeclampsia. S.l.: s.n.; 2003. 197p. ISBN 90-9016559-2 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Bleker OP, Spaan JAE; copromotor(s): Boer K, van Bavel ET)
van Wijk MJ, van Bavel E, Kublickiene KR, Isolated microparticles, but not whole plasma, from women with preeclampsia impair endothelium-dependent relaxation in isolated myometrial arteries from healthy pregnant women - Reply. AM J OBSTET GYNECOL 2003;189 (4):1209-1210
VanWijk MJ, VanBavel E, Sturk A, Nieuwland R, Microparticles in cardiovascular diseases. CARDIOVASC RES 2003;59 (2):277-287 [PubMed]
Bakker ENTP, van der Meulen ET, van den Berg BM, Everts V, Spaan JAE, VanBavel E, Inward remodeling follows chronic vasoconstriction in isolated resistance arteries. J VASC RES 2002;39 (1):12-20 [PubMed]
Cornelissen AJM, Dankelman J, VanBavel E, Spaan JAE, Balance between myogenic, flow-dependent, and metabolic flow control in coronary arterial tree: a model study. AM J PHYSIOL-HEART C 2002;282 (6):H2224-H2237 [PubMed]
Dekker RJ, van Soest S, Fontijn RD, Salamanca S, de Groot PG, VanBavel E, Pannekoek H, Horrevoets AJG, Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2). BLOOD 2002;100 (5):1689-1698 [PubMed]
Hollert N, Dürr M, Olsman H, Halldin K, van Bavel E, Brack W, Tysklind M, Engwall M, Braunbeck T, Biological and chemical determination of dioxin-like compounds in sediments by means of a sediment triad approach in the catchment area of the river Neckar. ECOTOXICOLOGY 2002;11 (5):323-336 [PubMed]
Sorop O, Spaan JAE, VanBavel E, Pulsation-induced dilation of subendocardial and subepicardial arterioles: effect on vasodilator sensitivity. AM J PHYSIOL-HEART C 2002;282 (1):H311-H319 [PubMed]
VanBavel E, Sorop O, Andreasen D, Pfaffendorf M, Jensen BL, Role of T-type calcium channels in myogenic tone of skeletal muscle resistance arteries. AM J PHYSIOL-HEART C 2002;283 (6):H2239-H2243 [PubMed]
VanWijk MJ, Boer K, Berckmans RJ, Meijers JCM, van der Post JAM, Sturk A, VanBavel E, Nieuwland R, Enhanced coagulation activation in preeclampsia: the role of APC resistance, microparticles and other plasma constituents. THROMB HAEMOSTASIS 2002;88 (3):415-420 [PubMed]
VanWijk MJ, Boer K, van der Meulen ET, Bleker OP, Spaan JAE, VanBavel E, Resistance artery smooth muscle function in pregnancy and preeclampsia. AM J OBSTET GYNECOL 2002;186 (1):148-154 [PubMed]
VanWijk MJ, Nieuwland R, Boer K, van der Post JAM, VanBavel E, Sturk A, Microparticle subpopulations are increased in preeclampsia: Possible involvement in vascular dysfunction?. AM J OBSTET GYNECOL 2002;187 (2):450-456 [PubMed]
VanWijk MJ, Svedas E, Boer K, Nieuwland R, VanBavel E, Kublickiene KR, Isolated microparticles, but not whole plasma, from women with preeclampsia impair endothelium-dependent relaxation in isolated myometrial arteries from healthy pregnant women. AM J OBSTET GYNECOL 2002;187 (6):1686-1693 [PubMed]
Bakker EN, Balt JC, Pfaffendorf M, Spaan JA, VanBavel E, Vasomotor effects of arg-gly-asp (RGD) peptides are limited and not related to endothelium-derived hyperpolarizing factor-mediated relaxation in rat mesenteric arteries. CLIN EXP PHARMACOL P 2001;28 (11):873-876 [PubMed]
Langerak SE, Groenink M, van der Wall EE, Wassenaar C, VanBavel E, van Baal MC, Spaan JA, Impact of current cryopreservation procedures on mechanical and functional properties of human aortic homografts. TRANSPL INT 2001;14 (4):248-255 [PubMed]
VanBavel E, van der Meulen ET, Spaan JA, Role of Rho-associated protein kinase in tone and calcium sensitivity of cannulated rat mesenteric small arteries. EXP PHYSIOL 2001;86 (5):585-592 [PubMed]
van Wijk MJ, Boer K, Nisell H, Smarason AK, van Bavel E, Kublickiene KR, Endothelial function in myometrial resistance arteries of normal pregnant women perfused with syncytiotrophoblast microvillous membranes. BJOG-INT J OBSTET GY 2001;108 (9):967-972 [PubMed]
Verkruysse W, Beek JF, VanBavel E, van Gemert MJ, Spaan JA, Laser pulse impact on rat mesenteric blood vessels in relation to laser treatment of port wine stain. LASER SURG MED 2001;28 (5):461-468 [PubMed]
Wesselman JP, Spaan JA, van der Meulen ET, VanBavel E, Role of protein kinase C in myogenic calcium-contraction coupling of rat cannulated mesenteric small arteries. CLIN EXP PHARMACOL P 2001;28 (10):848-855 [PubMed]
Bakker EN, van der Meulen ET, Spaan JA, VanBavel E, Organoid culture of cannulated rat resistance arteries: effect of serum factors on vasoactivity and remodeling. AM J PHYSIOL-HEART C 2000;278 (4):H1233-H1240 [PubMed]
Cornelissen AJ, Dankelman J, VanBavel E, Stassen HG, Spaan JA, Myogenic reactivity and resistance distribution in the coronary arterial tree: a model study. AM J PHYSIOL-HEART C 2000;278 (5):H1490-H1499 [PubMed]
VanWijk MJ, Kublickiene K, Boer K, VanBavel E, Vascular function in preeclampsia. CARDIOVASC RES 2000;47 (1):38-48 [PubMed]
Dekker LR, Coronel R, VanBavel E, Spaan JA, Opthof T, Intracellular Ca2+ and delay of ischemia-induced electrical uncoupling in preconditioned rabbit ventricular myocardium. CARDIOVASC RES 1999;44 (1):101-112 [PubMed]
Groenink M, Langerak SE, VanBavel E, van der Wall EE, Mulder BJ, van der Wal AC, Spaan JA, The influence of aging and aortic stiffness on permanent dilation and breaking stress of the thoracic descending aorta. CARDIOVASC RES 1999;43 (2):471-480 [PubMed]
VanBavel E, Wesselman JP, Spaan JA, Myogenic activation and calcium sensitivity of cannulated rat mesenteric small arteries. CIRC RES 1998;82 (2):210-220 [PubMed]
Wesselman JP, Schubert R, VanBavel ED, Nilsson H, Mulvany MJ, KCa-channel blockade prevents sustained pressure-induced depolarization in rat mesenteric small arteries. AM J PHYSIOL 1997;272 (5 Part 2):H2241-H2249 [PubMed]
Dekker LR, Fiolet JW, VanBavel E, Coronel R, Opthof T, Spaan JA, Janse MJ, Intracellular Ca2+, intercellular electrical coupling, and mechanical activity in ischemic rabbit papillary muscle. Effects of preconditioning and metabolic blockade. CIRC RES 1996;79 (2):237-246 [PubMed]
Goto M, VanBavel E, Giezeman MJ, Spaan JA, Vasodilatory effect of pulsatile pressure on coronary resistance vessels. CIRC RES 1996;79 (5):1039-1045 [PubMed]
Hacking WJ, VanBavel E, Spaan JA, Shear stress is not sufficient to control growth of vascular networks: a model study. AM J PHYSIOL 1996;270 (1 Part 2):H364-H375 [PubMed]
Wesselman JP, VanBavel E, Pfaffendorf M, Spaan JA, Voltage-operated calcium channels are essential for the myogenic responsiveness of cannulated rat mesenteric small arteries. J VASC RES 1996;33 (1):32-41 [PubMed]
Buus NH, VanBavel E, Mulvany MJ, Differences in sensitivity of rat mesenteric small arteries to agonists when studied as ring preparations or as cannulated preparations. BRIT J PHARMACOL 1994;112 (2):579-587 [PubMed]
Giezeman MJ, VanBavel E, Grimbergen CA, Spaan JA, Compliance of isolated porcine coronary small arteries and coronary pressure-flow relations. AM J PHYSIOL 1994;267 (3 Part 2):H1190-H1198 [PubMed]
VanBavel E, Mulvany MJ, Role of wall tension in the vasoconstrictor response of cannulated rat mesenteric small arteries. J PHYSIOL-LONDON 1994;477 ( Pt 1):103-115 [PubMed]
VanBavel E, Spaan JA, Branching patterns in the porcine coronary arterial tree. Estimation of flow heterogeneity. CIRC RES 1992;71 (5):1200-1212 [PubMed]
VanBavel E, Giezeman MJ, Mooij T, Spaan JA, Influence of pressure alterations on tone and vasomotion of isolated mesenteric small arteries of the rat. J PHYSIOL-LONDON 1991;436:371-383 [PubMed]
VanBavel E, Mooij T, Giezeman MJ, Spaan JA, Cannulation and continuous cross-sectional area measurement of small blood vessels. J PHARMACOL METHODS 1990;24 (3):219-227 [PubMed]
Ince C, van Duijn B, Ypey DL, van Bavel E, Weidema F, Leijh PC, Ionic channels and membrane hyperpolarization in human macrophages. J MEMBRANE BIOL 1987;97 (3):251-258 [PubMed]
Ince C, van Bavel E, van Duijn B, Donkersloot K, Coremans A, Ypey DL, Verveen AA, Intracellular microelectrode measurements in small cells evaluated with the patch clamp technique. BIOPHYS J 1986;50 (6):1203-1209 [PubMed]
Ince C, Leijh PC, Meijer J, van Bavel E, Ypey DL, Oscillatory hyperpolarizations and resting membrane potentials of mouse fibroblast and macrophage cell lines. J PHYSIOL-LONDON 1984;352:625-635 [PubMed]
Key publications

Coutinho JM, van den Berg R, Zuurbier SM, VanBavel E, Troost D, Majoie CB, Stam J, Small juxtacortical hemorrhages in cerebral venous thrombosis. ANN NEUROL 2014;75 (6):908-916 [PubMed]
Di Russo J, Luik AL, Yousif L, Budny S, Oberleithner H, Hofschröer V, Klingauf J, van Bavel E, Bakker EN, Hellstrand P, Bhattachariya A, Albinsson S, Pincet F, Hallmann R, Sorokin LM, Endothelial basement membrane laminin 511 is essential for shear stress response. EMBO J 2017;36 (2):183-201 [PubMed]
Heijtel DFR, Mutsaerts HJMM, Bakker E, Schober P, Stevens MF, Petersen ET, van Berckel BNM, Majoie CBLM, Booij J, van Osch MJP, VanBavel E, Boellaard R, Lammertsma AA, Nederveen AJ, Accuracy and precision of pseudo-continuous arterial spin labeling perfusion during baseline and hypercapnia: a head-to-head comparison with ¹⁵O H₂O positron emission tomography. NEUROIMAGE 2014;92:182-192 [PubMed]
Bakker ENTP, Groma G, Spijkers LJA, de Vos J, van Weert A, van Veen H, Everts V, Arribas SM, VanBavel E, Heterogeneity in arterial remodeling among sublines of spontaneously hypertensive rats. PLOS ONE 2014;9 (9):e107998 [PubMed]
VanBavel E, Tuna BG, Integrative modeling of small artery structure and function uncovers critical parameters for diameter regulation. PLOS ONE 2014;9 (1):e86901 [PubMed]


All Publications

Curriculum Vitae

A curriculum vitae is available upon request

Research programmes

Vascular Biophysics

I am coordinator of the FP7 European Union Research Training Network Small Artery Remodeling (‘SmArteR’, 2013-2017, www.smallartery.eu). Small arteries and arterioles form the major site of resistance for perfusion, and their function and structure are critical for tissue perfusion and regulation of blood pressure. The scientific objectives of SmArteR are 1) to better understand regulation of structure and function, with a focus on matrix and cell biology, mechanobiology and biomechanics; 2) to develop novel technology to study these blood vessels. This program should help early stage diagnosis and provide novel therapeutic options for adverse remodeling in among others hypertension.


We perform experimental work on vascular cognitive decline from two perspectives. In a first project, effects of micro-emboli on vascular and neuronal damage and repair are investigated. A second project addresses interstitial drainage and perivascular transport in relation to amyloid beta deposition. Experimental approaches include high resolution 3D imaging of vascular networks and transport processes, and rodent cranial window models.


We study structural changes of the vascular wall following sub-arachnoid hemorrhage, with purpose of understanding delayed cerebral ischemia. Experimental approaches include in vivo hemorrhage models and in vitro technology such as the cannulated vessel setup and so-called wire myograph.


Small arteries and arterioles form complex vascular networks. Regulation of arterial network structure and function is studied based on computer modeling, for the purpose of deciphering the critical vascular properties for control of perfusion. Input for such simulations is based on the large array of tests on individual vessels that we performed over the years, as well as on extensive datasets on vascular branching and (microsphere) flow that are being collected by the imaging cryomicrotome of Maria Siebes in our department.


In collaboration with the department of Radiology and funded from several sources, we established a research program on hemodynamic profiles in carotid and intracranial arteries, using novel phase contrast MRI approaches and computational techniques. The work aims to improve our understanding of the role of hemodynamics in vascular changes, and to provide tools for early diagnosis. Part of this work concerns risk of rupture models for intracranial aneurysms on the basis of local velocity and wall shear stress patterns. We also address wall shear stress in atherosclerosis. Furthermore we develop and validate new technology for cerebral perfusion based on ASL MRI. Also in collaboration with Radiology, we work on optimizing clinical image processing in among others stroke and Transcatheter Aortic Valve Implantation.


We employ a range of techniques for vascular biophysics and physiology. These include chronic in vivo flow diversion models, in vivo microscopy and cranial window models, isometric and isobaric functional tests on small arteries. Our methods for keeping isolated perfused blood vessels in culture and study in vitro remodeling have formed the base of much of our success. Likewise, we developed methods for the time-lapsed multiposition imaging of cells interaction with their surrounding matrix, and combine a range of optical techniques (side stream dark field imaging, FRAP, optical tweezers, OCT velocimetry) with in vivo microvascular imaging.


 

 

Faculty
Prof. dr. E.T. van Bavel
Dr. E.N.T.P. Bakker

PhD Students
B. Bedussi MSc
L. Casadonte MSc
Drs. F.A. Karamat
N. Lachkar MSc
A.E. de Leeuw
M.G.J.T.B. van Lier MSc
D.M.P. Naessens
Drs. R.H.G. Olde Engberink
T. Palao Garcia MSc (-)
H. Prasetya MEng
J.C.V. Schwarz MSc
L. Václavů MSc

Others
Ing. J. de Vos BSc
A. van Weert BSc

Other research related activities
  • editorships, conference scient boards, scient soc councils, ...., many
Current research funding
  • AMC
  • AMC (Vrijgesteld)
  • Europese Unie
  • Universiteit Twente