• Principal Investigator
  • Male

Prof. dr. P.J. Sterk

Position: Professor
Main activities: Research
Specialisation: Clinical Physiology: Pathogenesis and Pathophysiology of Airway Diseases
foto P.J. Sterk is one of the AMC Principal Investigators
Focus of research:
  • Pathophysiology and phenotyping of asthma and chronic obstructive pulmonary disease (COPD)
  • Structure-function relationships in the airways of patients with asthma and COPD
  • Gene expression profiling and in vivo function of airway smooth muscle in asthma
  • Use of biomarkers of airway inflammation and lung function in the prediction and monitoring of clinical outcome of respiratory diseases
  • Human in vivo models of asthma exacerbations by experimental rhinovirus infection, allergen, and/or particulate matter exposure
  • Breatheomics in exhaled air by AMC developed, big data cloud-based electronic nose technology as non-invasive and unbiased diagnostic assessment of respiratory diseases
AMC themes: Infection & Immunity
Departments: Pulmonology
Agustí A, Bafadhel M, Beasley R, Bel EH, Faner R, Gibson PG, Louis R, McDonald VM, Sterk PJ, Thomas M, Vogelmeier C, Pavord ID, Precision medicine in airway diseases: moving to clinical practice. EUR RESPIR J 2017;50 (4):1701655 [PubMed]
Berger M, de Boer JD, Lutter R, Makkee M, Sterk PJ, Kemper EM, van der Zee JS, Pulmonary challenge with carbon nanoparticles induces a dose-dependent increase in circulating leukocytes in healthy males. BMC PULM MED 2017;17 (1):121 [PubMed]
Bigler J, Boedigheimer M, Schofield JPR, Skipp PJ, Corfield J, Rowe A, Sousa AR, Timour M, Twehues L, Hu X, Roberts G, Welcher AA, Yu W, Lefaudeux D, Meulder BD, Auffray C, Chung KF, Adcock IM, Sterk PJ, Djukanović R, A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U-BIOPRED Cohorts. AM J RESP CRIT CARE 2017;195 (10):1311-1320 [PubMed]
Bousquet J, Bewick M, Cano A, Eklund P, Fico G, Goswami N, Guldemond NA, Henderson D, Hinkema MJ, Liotta G, Mair A, Molloy W, Monaco A, Monsonis-Paya I, Nizinska A, Papadopoulos H, Pavlickova A, Pecorelli S, Prados-Torres A, Roller-Wirnsberger RE, Somekh D, Vera-Muñoz C, Visser F, Farrell J, Malva J, Andersen Ranberg K, Camuzat T, Carriazo AM, Crooks G, Gutter Z, Iaccarino G, Manuel de Keenoy E, Moda G, Rodriguez-Mañas L, Vontetsianos T, Abreu C, Alonso J, Alonso-Bouzon C, Ankri J, Arredondo MT, Avolio F, Bedbrook A, Białoszewski AZ, Blain H, Bourret R, Cabrera-Umpierrez MF, Catala A, O'Caoimh R, Cesari M, Chavannes NH, Correia-da-Sousa J, Dedeu T, Ferrando M, Ferri M, Fokkens WJ, Garcia-Lizana F, Guérin O, Hellings PW, Haahtela T, Illario M, Inzerilli MC, Lodrup Carlsen KC, Kardas P, Keil T, Maggio M, Mendez-Zorrilla A, Menditto E, Mercier J, Michel JP, Murray R, Nogues M, O'Byrne-Maguire I, Pappa D, Parent AS, Pastorino M, Robalo-Cordeiro C, Samolinski B, Siciliano P, Teixeira AM, Tsartara SI, Valiulis A, Vandenplas O, Vasankari T, Vellas B, Vollenbroek-Hutten M, Wickman M, Yorgancioglu A, Zuberbier T, Barbagallo M, Canonica GW, Klimek L, Maggi S, Aberer W, Akdis C, Adcock IM, Agache I, Albera C, Alonso-Trujillo F, Angel Guarcia M, Annesi-Maesano I, Apostolo J, Arshad SH, Attalin V, Avignon A, Bachert C, Baroni I, Bel E, Benson M, Bescos C, Blasi F, Barbara C, Bergmann KC, Bernard PL, Bonini S, Bousquet PJ, Branchini B, Brightling CE, Bruguière V, Bunu C, Bush A, Caimmi DP, Calderon MA, Canovas G, Cardona V, Carlsen KH, Cesario A, Chkhartishvili E, Chiron R, Chivato T, Chung KF, d'Angelantonio M, de Carlo G, Cholley D, Chorin F, Combe B, Compas B, Costa DJ, Costa E, Coste O, Coupet AL, Crepaldi G, Custovic A, Dahl R, Dahlen SE, Demoly P, Devillier P, Didier A, Dinh-Xuan AT, Djukanovic R, Dokic D, du Toit G, Dubakiene R, Dupeyron A, Emuzyte R, Fiocchi A, Wagner A, Fletcher M, Fonseca J, Fougère B, Gamkrelidze A, Garces G, Garcia-Aymeric J, Garcia-Zapirain B, Gemicioğlu B, Gouder C, Hellquist-Dahl B, Hermosilla-Gimeno I, Héve D, Holland C, Humbert M, Hyland M, Johnston SL, Just J, Jutel M, Kaidashev IP, Khaitov M, Kalayci O, Kalyoncu AF, Keijser W, Kerstjens H, Knezović J, Kowalski M, Koppelman GH, Kotska T, Kovac M, Kull I, Kuna P, Kvedariene V, Lepore V, MacNee W, Magnan A, Majer I, Manning P, Marcucci M, Marti T, Masoli M, Melen E, Miculinic N, Mihaltan F, Milenkovic B, Millot-Keurinck J, Mlinarić H, Momas I, Montefort S, Morais-Almeida M, Moreno-Casbas T, Mösges R, Mullol J, Nadif R, Nalin M, Navarro-Pardo E, Nekam K, Ninot G, Paccard D, Pais S, Palummeri E, Panzner P, Papadopoulos NK, Papanikolaou C, Passalacqua G, Pastor E, Perrot M, Plavec D, Popov TA, Postma DS, Price D, Raffort N, Reuzeau JC, Robine JM, Rodenas F, Robusto F, Roche N, Romano A, Romano V, Rosado-Pinto J, Roubille F, Ruiz F, Ryan D, Salcedo T, Schmid-Grendelmeier P, Schulz H, Schunemann HJ, Serrano E, Sheikh A, Shields M, Siafakas N, Scichilone N, Skrindo I, Smit HA, Sourdet S, Sousa-Costa E, Spranger O, Sooronbaev T, Sruk V, Sterk PJ, Todo-Bom A, Touchon J, Tramontano D, Triggiani M, Valero AL, Valovirta E, van Ganse E, van Hage M, van den Berge M, Ventura MT, Vergara I, Vezzani G, Vidal D, Viegi G, Wagemann M, Whalley B, Wilson N, Yiallouros PK, Žagar M, Zaidi A, Zidarn M, Hoogerwerf EJ, Usero J, Zuffada R, Senn A, de Oliveira-Alves B, Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA. J NUTR HEALTH AGING 2017;21 (1):92-104 [PubMed]
Bousquet J, Farrell J, Crooks G, Hellings P, Bel EH, Bewick M, Chavannes NH, de Sousa JC, Cruz AA, Haahtela T, Joos G, Khaltaev N, Malva J, Muraro A, Nogues M, Palkonen S, Pedersen S, Robalo-Cordeiro C, Samolinski B, Strandberg T, Valiulis A, Yorgancioglu A, Zuberbier T, Bedbrook A, Aberer W, Adachi M, Agusti A, Akdis CA, Akdis M, Ankri J, Alonso A, Annesi-Maesano I, Ansotegui IJ, Anto JM, Arnavielhe S, Arshad H, Bai C, Baiardini I, Bachert C, Baigenzhin AK, Barbara C, Bateman ED, Beghé B, Ben Kheder A, Bennoor KS, Benson M, Bergmann KC, Bieber T, Bindslev-Jensen C, Bjermer L, Blain H, Blasi F, Boner AL, Bonini M, Bonini S, Bosnic-Anticevitch S, Boulet LP, Bourret R, Bousquet PJ, Braido F, Briggs AH, Brightling CE, Brozek J, Buhl R, Burney PG, Bush A, Caballero-Fonseca F, Caimmi D, Calderon MA, Calverley PM, Camargos PAM, Canonica GW, Camuzat T, Carlsen KH, Carr W, Carriazo A, Casale T, Cepeda Sarabia AM, Chatzi L, Chen YZ, Chiron R, Chkhartishvili E, Chuchalin AG, Chung KF, Ciprandi G, Cirule I, Cox L, Costa DJ, Custovic A, Dahl R, Dahlen SE, Darsow U, de Carlo G, de Blay F, Dedeu T, Deleanu D, de Manuel Keenoy E, Demoly P, Denburg JA, Devillier P, Didier A, Dinh-Xuan AT, Djukanovic R, Dokic D, Douagui H, Dray G, Dubakiene R, Durham SR, Dykewicz MS, El-Gamal Y, Emuzyte R, Fabbri LM, Fletcher M, Fiocchi A, Fink Wagner A, Fonseca J, Fokkens WJ, Forastiere F, Frith P, Gaga M, Gamkrelidze A, Garces J, Garcia-Aymerich J, Gemicioğlu B, Gereda JE, González Diaz S, Gotua M, Grisle I, Grouse L, Gutter Z, Guzmán MA, Heaney LG, Hellquist-Dahl B, Henderson D, Hendry A, Heinrich J, Heve D, Horak F, Hourihane JOB, Howarth P, Humbert M, Hyland ME, Illario M, Ivancevich JC, Jardim JR, Jares EJ, Jeandel C, Jenkins C, Johnston SL, Jonquet O, Julge K, Jung KS, Just J, Kaidashev I, Khaitov MR, Kalayci O, Kalyoncu AF, Keil T, Keith PK, Klimek L, Koffi N'goran B, Kolek V, Koppelman GH, Kowalski ML, Kull I, Kuna P, Kvedariene V, Lambrecht B, Lau S, Larenas-Linnemann D, Laune D, Le LTT, Lieberman P, Lipworth B, Li J, Lodrup Carlsen K, Louis R, MacNee W, Magard Y, Magnan A, Mahboub B, Mair A, Majer I, Makela MJ, Manning P, Mara S, Marshall GD, Masjedi MR, Matignon P, Maurer M, Mavale-Manuel S, Melén E, Melo-Gomes E, Meltzer EO, Menzies-Gow A, Merk H, Michel JP, Miculinic N, Mihaltan F, Milenkovic B, Mohammad GMY, Molimard M, Momas I, Montilla-Santana A, Morais-Almeida M, Morgan M, Mösges R, Mullol J, Nafti S, Namazova-Baranova L, Naclerio R, Neou A, Neffen H, Nekam K, Niggemann B, Ninot G, Nyembue TD, O'Hehir RE, Ohta K, Okamoto Y, Okubo K, Ouedraogo S, Paggiaro P, Pali-Schöll I, Panzner P, Papadopoulos N, Papi A, Park HS, Passalacqua G, Pavord I, Pawankar R, Pengelly R, Pfaar O, Picard R, Pigearias B, Pin I, Plavec D, Poethig D, Pohl W, Popov TA, Portejoie F, Potter P, Postma D, Price D, Rabe KF, Raciborski F, Radier Pontal F, Repka-Ramirez S, Reitamo S, Rennard S, Rodenas F, Roberts J, Roca J, Rodriguez Mañas L, Rolland C, Roman Rodriguez M, Romano A, Rosado-Pinto J, Rosario N, Rosenwasser L, Rottem M, Ryan D, Sanchez-Borges M, Scadding GK, Schunemann HJ, Serrano E, Schmid-Grendelmeier P, Schulz H, Sheikh A, Shields M, Siafakas N, Sibille Y, Similowski T, Simons FER, Sisul JC, Skrindo I, Smit HA, Solé D, Sooronbaev T, Spranger O, Stelmach R, Sterk PJ, Sunyer J, Thijs C, To T, Todo-Bom A, Triggiani M, Valenta R, Valero AL, Valia E, Valovirta E, van Ganse E, van Hage M, Vandenplas O, Vasankari T, Vellas B, Vestbo J, Vezzani G, Vichyanond P, Viegi G, Vogelmeier C, Vontetsianos T, Wagenmann M, Wallaert B, Walker S, Wang DY, Wahn U, Wickman M, Williams DM, Williams S, Wright J, Yawn BP, Yiallouros PK, Yusuf OM, Zaidi A, Zar HJ, Zernotti ME, Zhang L, Zhong N, Zidarn M, Mercier J, Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) (vol 6, 29, 2016). CLIN TRANSL ALLERGY 2017;7:5 [PubMed]
Brinkman P, van de Pol MA, Gerritsen MG, Bos LD, Dekker T, Smids BS, Sinha A, Majoor CJ, Sneeboer MM, Knobel HH, Vink TJ, de Jongh FH, Lutter R, Sterk PJ, Fens N, Exhaled breath profiles in the monitoring of loss of control and clinical recovery in asthma. CLIN EXP ALLERGY 2017;47 (9):1159-1169 [PubMed]
Coates AL, Wanger J, Cockcroft DW, Culver BH, Diamant Z, Gauvreau G, Hall GL, Hallstrand TS, Horvath I, de Jongh FHC, Joos G, Kaminsky DA, Laube BL, Leuppi JD, Sterk PJ, ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests. EUR RESPIR J 2017;49 (5):1601526 [PubMed]
d'Hooghe JNS, ten Hacken NH, Weersink EJM, Sterk PJ, Annema JT , Bonta PI, Emerging understanding of the mechanism of action of Bronchial Thermoplasty in asthma. PHARMACOL THERAPEUT 2017;ahead of print [PubMed]
Gerritsen MG, Brinkman P, Escobar N, Bos LD, de Heer K, Meijer M, Janssen HG, de Cock H, Wösten HAB, Visser CE, van Oers MHJ, Sterk PJ, Profiling of volatile organic compounds produced by clinical Aspergillus isolates using gas chromatography-mass spectrometry. MED MYCOL 2017;ahead of print [PubMed]
Hekking PP, Loza MJ, Pavlidis S, de Meulder B, Lefaudeux D, Baribaud F, Auffray C, Wagener AH , Brinkman P, Lutter R, Bansal AT, Sousa AR, Bates SA, Pandis I, Fleming LJ, Shaw DE, Fowler SJ, Guo Y, Meiser A, Sun K, Corfield J, Howarth P, Bel EH, Adcock IM, Chung KF, Djukanovic R, Sterk PJ, Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma. EUR RESPIR J 2017;50 (3):1602298 [PubMed]
Hekking PP, Loza MJ, Pavlidis S, de Meulder B, Lefaudeux D, Baribaud F, Auffray C, Wagener AH , Brinkman P, Lutter R, Bansal AT, Sousa AR, Bates S, Pandis Y, Fleming LJ, Shaw DE, Fowler SJ, Guo Y, Meiser A, Sun K, Corfield J, Howarth P, Bel EH, Adcock IM, Chung KF, Djukanovic R, Sterk PJ, Pathway discovery using transcriptomic profiles in adult-onset severe asthma. J ALLERGY CLIN IMMUN 2017;-:- [PubMed]
Hellings PW, Fokkens WJ, Bachert C, Akdis CA, Bieber T, Agache I, Bernal-Sprekelsen M, Canonica GW, Gevaert P, Joos G, Lund V, Muraro A, Onerci M, Zuberbier T, Pugin B, Seys SF, Bousquet J [Contributors: Aberer W, Agache I, Akdis CA, Akdis M, Alobid I, Ankri J, Annesi-Maesano I, Ansotegui IJ, Anto JM, Arnavielhe S, Arshad H, Asarnoj A, Avolio F, Bachert C, Baiardini I, Barbagallo M, Barbara C, Baroody F, Bateman ED, Bedbrook A, Beghé B, Bel EH, Bennoor KS, Benson M, Bergmann KC, Bewick M, Bialoszewski AZ, Bieber T, Bindslev-Jensen C, Bjermer L, Blain H, Blasi F, Boner AL, Bonini M, Bonini S, Bosnic-Anticevich S, Bosse I, Bouchard J, Boulet LP, Bourret R, Bousquet J, Bousquet PJ, Braido F, Briggs AH, Brightling CE, Brozek J, Bucca C, Buhl R, Bunu C, Burte E, Bush A, Caballero-Fonseca F, Caimmi DP, Calderon MA, Camargos PA, Camuzat T, Canonica GW, Cardona V, Carlsen KH, Carr W, Carreiro-Martins P, Carriazo AM, Casale T, Cepeda Sarabia AM, Cervin A, Cesari M, Chatzi L, Chavannes NH, Chiron R, Chivato T, Chkhartishvili E, Chuchalin AG, Chung KF, Ciprandi G, Cohen N, Conzález Diaz S, Cox L, Crooks G, Cruz AA, Custovic A, Dahl R, Dahlen SE, Darsow U, de Carlo G, de Manuel Keenoy E, de Sousa JC, de Vries G, Dedeu T, Deleanu D, Demoly P, Denburg JA, Devillier P, Didier A, Dinh-Xuan AT, Dokic D, Douagui H, Douglas R, Dray G, du Toit G, Dubakiene R, Durham SR, Dykewicz MS, Eklund P, El-Gamal Y, Ellers E, Emuzyte R, Farrell J, Fink Wagner A, Fiocchi A, Fletcher M, Fokkens WJ, Fonseca J, Forastiere F, Gaga M, Gamkrelidze A, Gemicioğlu B, Georgalas C, Gereda JE, Gevaert P, Goossens H, Grisle I, Guldemond NA, Gutter Z, Guzmán MA, Haahtela T, Harvey R, Heinrich J, Hellings PW, Hellquist-Dahl B, Hopkins C, Horak F, Hourihane JO, Humbert M, Hyland M, Iaccarino G, Illario M, Jares EJ, Jeandel C, Johnston SL, Jonquet O, Joos G, Jung KS, Just J, Jutel M, Kaidashev I, Kalayci O, Kalogjera L, Kalyoncu AF, Kardas P, Keil T, Keith PK, Kerkhof M, Kern B, Kerstjens HA, Khaitov M, Khaltaev N, Klimek L, Kogevinas M, Kolek V, Koppelman GH, Kowalski M, Kowalski ML, Kuitunen M, Kull I, Kuna P, Kvedariene V, Lambrecht B, Larenas-Linnemann D, Lau S, Laune D, Le LT, Li J, Lieberman P, Lipworth B, Lodrup Carlsen KC, Louis R, Lund VJ, Lupinek C, MacNee W, Magar Y, Magnan A, Mahboub B, Maier D, Majer I, Malva J, Manning P, Marshall GD, Masjedi MR, Mathieu-Dupas E, Maurer M, Mavale-Manuel S, Melén E, Melo-Gomes E, Meltzer EO, Mercier J, Merk H, Miculinic N, Mihaltan F, Milenkovic B, Millot-Keurinck J, Mohammad Y, Momas I, Morais-Almeida M, Mösges R, Mullol J, Muraro A, Murray R, Naclerio R, Nadif R, Namazova-Baranova L, Neffen H, Nekam K, Nieto A, Niggemann B, Nogueira-Silva L, Nogues M, Nyembue TD, O'Hehir RE, Ohta K, Okamoto Y, Okubo K, Olive-Elias M, Ouedraogo S, Paggiaro P, Pali-Schöll I, Palkonen S, Panzner P, Papadopoulos NG, Papi A, Park HS, Passalacqua G, Pawankar R, Pedersen S, Pereira AM, Pfaar O, Picard R, Pigearias B, Pin I, Plavec D, Pohl W, Popov TA, Portejoie F, Postma D, Potter P, Poulsen LK, Price D, Rabe KF, Raciborski F, Riechelmann H, Robalo-Cordeiro C, Roberts G, Rodenas F, Rodriguez-Mañas L, Rolland C, Roman Rodriguez M, Romano A, Rosado-Pinto J, Rosario N, Rottem M, Ryan D, Samolinski B, Sanchez-Borges M, Sastre-Dominguez J, Scadding GK, Schlosser R, Schmid-Grendelmeier P, Schunemann HJ, Scichilone N, Senior B, Serrano E, Sheikh A, Shields M, Simons F, Siroux V, Sisul JC, Skrindo I, Smit HA, Solé D, Sooronbaev T, Spranger O, Stellato C, Stelmach R, Sterk PJ, Strandberg T, Sunyer J, Thijs C, Thomas M, Todo-Bom A, Tomazic PV, Toskala E, Triggiani M, Valenta R, Valero A, Valiulis A, Valovirta E, van Eerd M, van Ganse E, van Hage M, van Wick RG, Vandenplas O, Varona LL, Vazankari T, Vellas B, Ventura MT, Vezzani G, Viegi G, Voegels R, Vontetsianos T, Wagenmann M, Wahn U, Walker S, Wang DY, Wang Y, Werfel T, Whalley B, Wickman M, Williams DM, Williams S, Wilson N, Wormald PJ, Wright J, Yawn BP, Yiallouros PK, Yorgancioglu A, Young I, Yusuf OM, Zaidi A, Zar HJ, Zernotti ME, Zhang L, Zhong N, Zidarn M, Zuberbier T]] , Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis - A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement. ALLERGY 2017;72 (9):1297-1305 [PubMed]
Honkoop PJ, Pinnock H, Kievits-Smeets RMM, Sterk PJ, Dekhuijzen PNR, in 't Veen JCCM, Adaptation of a difficult-to-manage asthma programme for implementation in the Dutch context: a modified e-Delphi. NPJ PRIM CARE RESP M 2017;27:16086 [PubMed]
Horváth I, Barnes PJ, Loukides S, Sterk PJ, Högman M, Olin AC, Amann A, Antus B, Baraldi E, Bikov A, Boots AW, Bos LD , Brinkman P, Bucca C, Carpagnano GE, Corradi M, Cristescu S, de Jongste JC, Dinh-Xuan AT, Dompeling E, Fens N, Fowler S, Hohlfeld JM, Holz O, Jöbsis Q, van de Kant K, Knobel HH, Kostikas K, Lehtimäki L, Lundberg J, Montuschi P, van Muylem A, Pennazza G, Reinhold P, Ricciardolo FLM, Rosias P, Santonico M, van der Schee MP, van Schooten FJ, Spanevello A, Tonia T, Vink TJ, A European Respiratory Society technical standard: exhaled biomarkers in lung disease. EUR RESPIR J 2017;49 (4):1600965 [PubMed]
Kunz LIZ, ten Hacken NH, Lapperre TS, Timens W, Kerstjens HAM, van Schadewijk A, Vonk JM, Sont JK, Snoeck-Stroband JB, Postma DS, Sterk PJ, Hiemstra PS, Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids. EUR RESPIR J 2017;49 (6):1700848 [PubMed]
Kunz LIZ, ten Hacken NHT, Lapperre TS, Timens W, Kerstjens HAM, van Schadewijk A, Vonk JM, Sont JK, Snoeck-Stroband JB, Postma DS, Sterk PJ, Hiemstra PS, Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids. EUR RESPIR J 2017;ahead of print [PubMed]
Kuo CHS, Pavlidis S, Loza M, Baribaud F, Rowe A, Pandis I, Hoda U, Rossios C, Sousa A, Wilson SJ, Howarth P, Dahlen B, Dahlen SE, Chanez P, Shaw D, Krug N, Sandstrӧm T, de Meulder B, Lefaudeux D, Fowler S, Fleming L, Corfield J, Auffray C, Sterk PJ, Djukanovic R, Guo Y, Adcock IM, Chung KF, A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED. AM J RESP CRIT CARE 2017;195 (4):443-455 [PubMed]
Kuo CHS, Pavlidis S, Loza M, Baribaud F, Rowe A, Pandis I, Sousa A, Corfield J, Djukanovic R, Lutter R, Sterk PJ, Auffray C, Guo Y, Adcock IM, Chung KF, T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED. EUR RESPIR J 2017;ahead of print [PubMed]
Lamote K, Brinkman P, Vandermeersch L, Vynck M, Sterk PJ, van Langenhove H, Thas O, van Cleemput J, Nackaerts K, van Meerbeeck JP, Breath analysis by gas chromatography-mass spectrometry and electronic nose to screen for pleural mesothelioma: a cross-sectional case-control study. ONCOTARGET 2017;8 (53):91593-91602
Lefaudeux D, de Meulder B, Loza MJ, Peffer N, Rowe A, Baribaud F, Bansal AT, Lutter R, Sousa AR, Corfield J, Pandis I, Bakke PS, Caruso M, Chanez P, Dahlén SE, Fleming LJ, Fowler SJ, Horvath I, Krug N, Montuschi P, Sanak M, Sandstrom T, Shaw DE, Singer F, Sterk PJ, Roberts G, Adcock IM, Djukanovic R, Auffray C, Chung KF [Contributors: Adriaens N, Ahmed H, Aliprantis A, Alving K, Badorek P, Balgoma D, Barber C, Bautmans A, Behndig AF, Bel E, Beleta J, Berglind A, Berton A, Bigler J, Bisgaard H, Bochenek G, Boedigheimer MJ, Bøonnelykke K, Brandsma J, Braun A, Brinkman P, Burg D, Campagna D, Carayannopoulos L, Carvalho da Purfição Rocha JP, Chaiboonchoe A, Chaleckis R, Coleman C, Compton C, D'Amico A, Dahlén B, de Alba J, de Boer P, de Lepeleire I, Dekker T, Delin I, Dennison P, Dijkhuis A, Draper A, Edwards J, Emma R, Ericsson M, Erpenbeck V, Erzen D, Faulenbach C, Fichtner K, Fitch N, Flood B, Frey U, Gahlemann M, Galffy G, Gallart H, Garret T, Geiser T, Gent J, Gerhardsson de Verdier M, Gibeon D, Gomez C, Gove K, Gozzard N, Guo YK, Hashimoto S, Haughney J, Hedlin G, Hekking PP, Henriksson E, Hewitt L, Higgenbottam T, Hoda U, Hohlfeld J, Holweg C, Howarth P, Hu R, Hu S, Hu X, Hudson V, James AJ, Kamphuis J, Kennington EJ, Kerry D, Klüglich M, Knobel H, Knowles R, Knox A, Kolmert J, Konradsen J, Kots M, Krueger L, Kuo S, Kupczyk M, Lambrecht B, Lantz AS, Larsson L, Lazarinis N, Lone-Satif S, Marouzet L, Martin J, Masefield S, Mathon C, Matthews JG, Mazein A, Meah S, Maiser A, Menzies-Gow A, Metcalf L, Middelveld R, Mikus M, Miralpeix M, Monk P, Mores N, Murray CS, Musial J, Myles D, Naz S, Nething K, Nicholas B, Nihlen U, Nilsson P, Nordlund B, Östling J, Pacino A, Pahus L, Palkonnen S, Pavlidis S, Pennazza G, Petrén A, Pink S, Postle A, Powel P, Rahman-Amin M, Rao N, Ravanetti L, Ray E, Reinke S, Reynolds L, Riemann K, Riley J, Robberechts M, Roberts A, Rossios C, Russell K, Rutgers M, Santini G, Sentoninco M, Schoelch C, Schofield JPR, Seibold W, Sigmund R, Sjödin M, Skipp PJ, Smids B, Smith C, Smith J, Smith KM, Söderman P, Sogbesan A, Staykova D, Strandberg K, Sun K, Supple D, Szentkereszty M, Tamasi L, Tariq K, Thörngren JO, Thornton B, Thorsen J, Valente S, van Aalderenm W, van de Pol M, van Drunen K, van Geest M, Versnel J, Vestbo J, Vink A, Vissing N, von Garnier C, Wagerner A, Wagers S, Wald F, Walker S, Ward J, Weiszhart Z, Wetzel K, Wheelock CE, Wiegman C, Williams S, Wilson SJ, Woosdcock A, Yang X, Yeyashingham E, Yu W, Zetterquist W, Zwinderman K]] , U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics. J ALLERGY CLIN IMMUN 2017;139 (6):1797-1807 [PubMed]
Leopold JH, Bos LDJ, Colombo C, Sterk PJ, Schultz MJ, Abu-Hanna A, Non-invasive breath monitoring with eNose does not improve glucose diagnostics in critically ill patients in comparison to continuous glucose monitoring in blood. J BREATH RES 2017;11 (2):026002 [PubMed]
Loymans RJ, Sterk PJ, Exacerbation-Prone Asthma: A Separate Bioclinical Phenotype?. AM J RESP CRIT CARE 2017;195 (3):275-277 [PubMed]
Neerincx AH, Vijverberg SJH, Bos LDJ, Brinkman P, van der Schee MP, de Vries R, Sterk PJ, Maitland-van der Zee AH, Breathomics from exhaled volatile organic compounds in pediatric asthma. PEDIATR PULM 2017;ahead of print [PubMed]
Nicholas B, Dudley S, Tariq K, Howarth P, Lunn K, Pink S, Sterk PJ, Adcock IM, Monk P, Djukanović R, Susceptibility to influenza virus infection of bronchial biopsies in asthma. J ALLERGY CLIN IMMUN 2017;140 (1):309-+ [PubMed]
Ravanetti L, Dijkhuis A, Sabogal Pineros YS, Bal SM, Dierdorp BS, Dekker T, Logiantara A, Adcock IM, Rao NL, Boon L, Villetti G, Sterk PJ, Facchinetti F, Lutter R, An early innate response underlies severe influenza-induced exacerbations of asthma in a novel steroid-insensitive and anti-IL-5-responsive mouse model. ALLERGY 2017;72 (5):737-753 [PubMed]
Rossios C, Pavlidis S, Hoda U, Kuo CH, Wiegman C, Russell K, Sun K, Loza MJ, Baribaud F, Durham AL, Ojo O, Lutter R, Rowe A, Bansal A, Auffray C, Sousa A, Corfield J, Djukanovic R, Guo Y, Sterk PJ, Chung KF, Adcock IM, Sputum transcriptomics reveal up-regulation of IL-1 receptor family members in severe asthma. J ALLERGY CLIN IMMUN 2017;ahead of print [PubMed]
Silkoff PE, Flavin S, Gordon R, Loza MJ, Sterk PJ, Lutter R, Diamant Z, Turner RB, Lipworth BJ, Proud D, Singh D, Eich A, Backer V, Gern JE, Herzmann C, Halperin SA, Mensinga TT, del Vecchio AM, Branigan P, San Mateo L, Baribaud F, Barnathan ES, Johnston SL, TLR3 Blockade in Rhinovirus-Induced Experimental Asthma Exacerbations: A Randomized Controlled Study. J ALLERGY CLIN IMMUN 2017;ahead of print [PubMed]
Sinha A, Sterk PJ, Proteomics in asthma: the clinicians were right after all, were not they?. CLIN TRANSL MED 2017;6 (1):39 [PubMed]
Sterk PJ, A good asthma catch by professional fishing. EUR RESPIR J 2017;49 (3):1602564 [PubMed]
Thamrin C, Frey U, Kaminsky DA, Reddel HK, Seely AJE, Suki B, Sterk PJ, Reply: Complexity Analysis of Respiratory Dynamics. AM J RESP CRIT CARE 2017;196 (2):248-249 [PubMed]
van Oort PMP, Nijsen T, Weda H, Knobel H, Dark P, Felton T, Rattray NJW, Lawal O, Ahmed W, Portsmouth C, Sterk PJ, Schultz MJ, Zakharkina T, Artigas A, Povoa P, Martin-Loeches I, Fowler SJ, Bos LDJ [Contributors: Ahmed W, Artigas A, Bos LDJ, Camprubi M, Coelho L, Dark P, Davie A, Diaz E, Goma G, Felton T, Fowler SJ, Goodacre R, Knobel H, Lawal O, Leopold JH, Martin-Loeches I, Nijsen T, van Oort PMP, Povoa P, Portsmouth C, Rattray NJW, Rijnders G, Schultz MJ, Steenwelle R, Sterk PJ, Valles J, Verhoeckx F, Vink A, Weda H, Winters T, Zakharkina T]] , BreathDx - molecular analysis of exhaled breath as a diagnostic test for ventilator-associated pneumonia: protocol for a European multicentre observational study. BMC PULM MED 2017;17 (1):1 [PubMed]
van Velzen P , ter Riet G, Bresser P, Baars JJ, van den Berg BTJ, van den Berg JWK, Brinkman P, Dagelet JWF, Daniels JMA, Groeneveld-Tjiong DRGL, Jonkers RE, van Kan C, Krouwels FH, Pool K, Rudolphus A, Sterk PJ, Prins JM, Doxycycline for outpatient-treated acute exacerbations of COPD: a randomised double-blind placebo-controlled trial. LANCET RESP MED 2017;5 (6):492-499 [PubMed]
Westerhof GA. Adult-onset asthma: Predictors of clinical course and severity. S.l.: s.n.; 2017. 191p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Bel EHD; copromotor(s): Weersink EJM, Sterk PJ)
Yii ACA, Tan JHY, Lapperre TS, Chan AKW, Low SY, Ong TH, Tan KL, Chotirmall SH, Sterk PJ, Koh MS, Long-term future risk of severe exacerbations: Distinct 5-year trajectories of problematic asthma. ALLERGY 2017;72 (9):1398-1405 [PubMed]
Zakharkina T, Martin-Loeches I, Matamoros S, Povoa P, Torres A, Kastelijn JB, Hofstra JJ, de Wever B, de Jong M, Schultz MJ, Sterk PJ, Artigas A, Bos LDJ, The dynamics of the pulmonary microbiome during mechanical ventilation in the intensive care unit and the association with occurrence of pneumonia. THORAX 2017;72 (9):803-810 [PubMed]
Berger M, Kooyman PJ, Makkee M, van der Zee JS, Sterk PJ, van Dijk J, Kemper EM, How to achieve safe, high-quality clinical studies with non-Medicinal Investigational Products? A practical guideline by using intra-bronchial carbon nanoparticles as case study. RESP RES 2016;17 (1):102 [PubMed]
Bos LD , Sterk PJ, Fowler SJ, Breathomics in the setting of asthma and chronic obstructive pulmonary disease. J ALLERGY CLIN IMMUN 2016;138 (4):970-976 [PubMed]
Bousquet J, Barbara C, Bateman E, Bel E, Bewick M, Chavannes NH, Cruz AA, Haahtela T, Hellings PW, Khaltaev N, Lodrup Carlsen K, Muraro A, Cordeiro CR, Rosado-Pinto J, Samolinski B, Strandberg T, Valiulis A, Yorgancioglu A, Zuberbier T [Contributors: Adcock I, Addis A, Agache I, Agusti A, Alonso A, Annesi Maesano I, Anto JM, Baena-Cagnani C, Bai C, Baigenzhin A, Barnes PJ, Beck L, Bedbrook A, Benezet O, Bennoor KS, Benson M, Bindslev Jensen C, Blain H, Blasi F, Bonini M, Bonini S, Boulet LP, Bourdin A, Bourret R, Brightling CE, Briggs A, Brozek J, Buhl R, Bush A, Caimmi D, Calderon M, Calverley P, Camargos P, Canonica GW, Carlsen KH, Casale TB, Cazzola M, Cepeda Sarabia AM, Cesario A, Chen YZ, Chiron R, Chuchalin A, Chung KF, Cox L, Crooks G, Crooks MG, Custovic A, Dahl R, Dahlen SE, Dedeu T, Deleanu D, Demoly P, Devillier P, Didier A, Dinh Xuan AT, Djukanovic R, Dokic D, Douagui H, Eglin S, Elliot F, Emuzyte R, Fabbri L, Fink-Wagner A, Fletcher M, Fokkens WJ, Fonseca J, Franco A, Furber A, Gaga M, Gamkrelidze A, Garcia Aymerich J, González-Díaz S, Gouzi F, Garcés J, Guzmán MA, Hayot M, Heaney L, Heinrich J, Hooper J, Humbert M, Hyland M, Iaccarino G, Jakovenko D, Jardim J, Jenkins C, Johnston SL, Jonquet O, Joos G, Jung KS, Kalayci O, Karunanithi S, Keil T, Kolek V, Kowalski M, Kuna P, Kvedariene V, Le LT, Louis R, MacNee W, Mair A, Manning P, Manuel Keenoy ME, Majer I, Melén E, Melo Gomes E, Menzies-Gow A, Mercier G, Mercier J, Michel JP, Miculinic N, Mihaltan F, Milenkovic B, Momas I, Montilla-Santana A, Morais Almeida M, Morgan M, N'Diaye M, Nafti S, O'Hehir R, Ohta K, Paggiaro P, Palkonen S, Palmer S, Papadopoulos NG, Papi A, Passalacqua G, Pavord I, Pigearias B, Plavec D, Postma DS, Price D, Rabe KF, Radier Pontal F, Redon J, Rennard S, Roberts J, Roca J, Roche N, Rodenas F, Roggeri A, Rolland C, Ryan D, Sanchez-Borges M, Schünemann HJ, Sheikh A, Siafakas N, Sibille Y, Similowski T, Small I, Sola-Morales O, Sooronbaev T, Stelmach R, Sterk PJ, Stiris T, Sud P, To T, Todo Bom A, Triggiani M, Valenta R, Valero AL, Valovirta E, Vandenplas O, van Ganse E, Vestbo J, Vezzani G, Viegi G, Visier L, Vogelmeier C, Vontetsianos T, Wagstaff R, Wallaert B, Wahn U, Whalley B, Williams D, Wilson N, Yawn BP, Yiallouros P, Yusuf O, Zar HJ, Zhong N, Zidarn M]] , AIRWAYS-ICPs (European Innovation Partnership on Active and Healthy Ageing) from concept to implementation. EUR RESPIR J 2016;47 (4):1028-1033 [PubMed]
Bousquet J, Farrell J, Crooks G, Hellings P, Bel EH, Bewick M, Chavannes NH, de Sousa JC, Cruz AA, Haahtela T, Joos G, Khaltaev N, Malva J, Muraro A, Nogues M, Palkonen S, Pedersen S, Robalo-Cordeiro C, Samolinski B, Strandberg T, Valiulis A, Yorgancioglu A, Zuberbier T, Bedbrook A, Aberer W, Adachi M, Agusti A, Akdis CA, Akdis M, Ankri J, Alonso A, Annesi-Maesano I, Ansotegui IJ, Anto JM, Arnavielhe S, Arshad H, Bai C, Baiardini I, Bachert C, Baigenzhin AK, Barbara C, Bateman ED, Beghé B, Kheder AB, Bennoor KS, Benson M, Bergmann KC, Bieber T, Bindslev-Jensen C, Bjermer L, Blain H, Blasi F, Boner AL, Bonini M, Bonini S, Bosnic-Anticevitch S, Boulet LP, Bourret R, Bousquet PJ, Braido F, Briggs AH, Brightling CE, Brozek J, Buhl R, Burney PG, Bush A, Caballero-Fonseca F, Caimmi D, Calderon MA, Calverley PM, Camargos PAM, Canonica GW, Camuzat T, Carlsen KH, Carr W, Carriazo A, Casale T, Cepeda Sarabia AM, Chatzi L, Chen YZ, Chiron R, Chkhartishvili E, Chuchalin AG, Chung KF, Ciprandi G, Cirule I, Cox L, Costa DJ, Custovic A, Dahl R, Dahlen SE, Darsow U, de Carlo G, de Blay F, Dedeu T, Deleanu D, de Manuel Keenoy E, Demoly P, Denburg JA, Devillier P, Didier A, Dinh-Xuan AT, Djukanovic R, Dokic D, Douagui H, Dray G, Dubakiene R, Durham SR, Dykewicz MS, El-Gamal Y, Emuzyte R, Fabbri LM, Fletcher M, Fiocchi A, Fink Wagner A, Fonseca J, Fokkens WJ, Forastiere F, Frith P, Gaga M, Gamkrelidze A, Garces J, Garcia-Aymerich J, Gemicioğlu B, Gereda JE, González Diaz S, Gotua M, Grisle I, Grouse L, Gutter Z, Guzmán MA, Heaney LG, Hellquist-Dahl B, Henderson D, Hendry A, Heinrich J, Heve D, Horak F, Hourihane JOB, Howarth P, Humbert M, Hyland ME, Illario M, Ivancevich JC, Jardim JR, Jares EJ, Jeandel C, Jenkins C, Johnston SL, Jonquet O, Julge K, Jung KS, Just J, Kaidashev I, Kaitov MR, Kalayci O, Kalyoncu AF, Keil T, Keith PK, Klimek L, Koffi N'goran B, Kolek V, Koppelman GH, Kowalski ML, Kull I, Kuna P, Kvedariene V, Lambrecht B, Lau S, Larenas-Linnemann D, Laune D, Le LTT, Lieberman P, Lipworth B, Li J, Lodrup Carlsen K, Louis R, MacNee W, Magard Y, Magnan A, Mahboub B, Mair A, Majer I, Makela MJ, Manning P, Mara S, Marshall GD, Masjedi MR, Matignon P, Maurer M, Mavale-Manuel S, Melén E, Melo-Gomes E, Meltzer EO, Menzies-Gow A, Merk H, Michel JP, Miculinic N, Mihaltan F, Milenkovic B, Mohammad GMY, Molimard M, Momas I, Montilla-Santana A, Morais-Almeida M, Morgan M, Mösges R, Mullol J, Nafti S, Namazova-Baranova L, Naclerio R, Neou A, Neffen H, Nekam K, Niggemann B, Ninot G, Nyembue TD, O'Hehir RE, Ohta K, Okamoto Y, Okubo K, Ouedraogo S, Paggiaro P, Pali-Schöll I, Panzner P, Papadopoulos N, Papi A, Park HS, Passalacqua G, Pavord I, Pawankar R, Pengelly R, Pfaar O, Picard R, Pigearias B, Pin I, Plavec D, Poethig D, Pohl W, Popov TA, Portejoie F, Potter P, Postma D, Price D, Rabe KF, Raciborski F, Radier Pontal F, Repka-Ramirez S, Reitamo S, Rennard S, Rodenas F, Roberts J, Roca J, Rodriguez Mañas L, Rolland C, Roman Rodriguez M, Romano A, Rosado-Pinto J, Rosario N, Rosenwasser L, Rottem M, Ryan D, Sanchez-Borges M, Scadding GK, Schunemann HJ, Serrano E, Schmid-Grendelmeier P, Schulz H, Sheikh A, Shields M, Siafakas N, Sibille Y, Similowski T, Simons FER, Sisul JC, Skrindo I, Smit HA, Solé D, Sooronbaev T, Spranger O, Stelmach R, Sterk PJ, Sunyer J, Thijs C, To T, Todo-Bom A, Triggiani M, Valenta R, Valero AL, Valia E, Valovirta E, van Ganse E, van Hage M, Vandenplas O, Vasankari T, Vellas B, Vestbo J, Vezzani G, Vichyanond P, Viegi G, Vogelmeier C, Vontetsianos T, Wagenmann M, Wallaert B, Walker S, Wang DY, Wahn U, Wickman M, Williams DM, Williams S, Wright J, Yawn BP, Yiallouros PK, Yusuf OM, Zaidi A, Zar HJ, Zernotti ME, Zhang L, Zhong N, Zidarn M, Mercier J, Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5). CLIN TRANSL ALLERGY 2016;6:29 [PubMed]
Bousquet J, Hellings PW, Agache I, Bedbrook A, Bachert C, Bergmann KC, Bewick M, Bindslev-Jensen C, Bosnic-Anticevitch S, Bucca C, Caimmi DP, Camargos PAM, Canonica GW, Casale T, Chavannes NH, Cruz AA, de Carlo G, Dahl R, Demoly P, Devillier P, Fonseca J, Fokkens WJ, Guldemond NA, Haahtela T, Illario M, Just J, Keil T, Klimek L, Kuna P, Larenas-Linnemann D, Morais-Almeida M, Mullol J, Murray R, Naclerio R, O'Hehir RE, Papadopoulos NG, Pawankar R, Potter P, Ryan D, Samolinski B, Schunemann HJ, Sheikh A, Simons FER, Stellato C, Todo-Bom A, Tomazic PV, Valiulis A, Valovirta E, Ventura MT, Wickman M, Young I, Yorgancioglu A, Zuberbier T, Aberer W, Akdis CA, Akdis M, Annesi-Maesano I, Ankri J, Ansotegui IJ, Anto JM, Arnavielhe S, Asarnoj A, Arshad H, Avolio F, Baiardini I, Barbara C, Barbagallo M, Bateman ED, Beghé B, Bel EH, Bennoor KS, Benson M, Białoszewski AZ, Bieber T, Bjermer L, Blain H, Blasi F, Boner AL, Bonini M, Bonini S, Bosse I, Bouchard J, Boulet LP, Bourret R, Bousquet PJ, Braido F, Briggs AH, Brightling CE, Brozek J, Buhl R, Bunu C, Burte E, Bush A, Caballero-Fonseca F, Calderon MA, Camuzat T, Cardona V, Carreiro-Martins P, Carriazo AM, Carlsen KH, Carr W, Cepeda Sarabia AM, Cesari M, Chatzi L, Chiron R, Chivato T, Chkhartishvili E, Chuchalin AG, Chung KF, Ciprandi G, de Sousa JC, Cox L, Crooks G, Custovic A, Dahlen SE, Darsow U, Dedeu T, Deleanu D, Denburg JA, de Vries G, Didier A, Dinh-Xuan AT, Dokic D, Douagui H, Dray G, Dubakiene R, Durham SR, du Toit G, Dykewicz MS, Eklund P, El-Gamal Y, Ellers E, Emuzyte R, Farrell J, Fink Wagner A, Fiocchi A, Fletcher M, Forastiere F, Gaga M, Gamkrelidze A, Gemicioğlu B, Gereda JE, van Wick RG, González Diaz S, Grisle I, Grouse L, Gutter Z, Guzmán MA, Hellquist-Dahl B, Heinrich J, Horak F, Hourihane JOB, Humbert M, Hyland M, Iaccarino G, Jares EJ, Jeandel C, Johnston SL, Joos G, Jonquet O, Jung KS, Jutel M, Kaidashev I, Khaitov M, Kalayci O, Kalyoncu AF, Kardas P, Keith PK, Kerkhof M, Kerstjens HAM, Khaltaev N, Kogevinas M, Kolek V, Koppelman GH, Kowalski ML, Kuitunen M, Kull I, Kvedariene V, Lambrecht B, Lau S, Laune D, Le LTT, Lieberman P, Lipworth B, Li J, Lodrup Carlsen KC, Louis R, Lupinek C, MacNee W, Magar Y, Magnan A, Mahboub B, Maier D, Majer I, Malva J, Manning P, de Manuel Keenoy E, Marshall GD, Masjedi MR, Mathieu-Dupas E, Maurer M, Mavale-Manuel S, Melén E, Melo-Gomes E, Meltzer EO, Mercier J, Merk H, Miculinic N, Mihaltan F, Milenkovic B, Millot-Keurinck J, Mohammad Y, Momas I, Mösges R, Muraro A, Namazova-Baranova L, Nadif R, Neffen H, Nekam K, Nieto A, Niggemann B, Nogueira-Silva L, Nogues M, Nyembue TD, Ohta K, Okamoto Y, Okubo K, Olive-Elias M, Ouedraogo S, Paggiaro P, Pali-Schöll I, Palkonen S, Panzner P, Papi A, Park HS, Passalacqua G, Pedersen S, Pereira AM, Pfaar O, Picard R, Pigearias B, Pin I, Plavec D, Pohl W, Popov TA, Portejoie F, Postma D, Poulsen LK, Price D, Rabe KF, Raciborski F, Roberts G, Robalo-Cordeiro C, Rodenas F, Rodriguez-Mañas L, Rolland C, Roman Rodriguez M, Romano A, Rosado-Pinto J, Rosario N, Rottem M, Sanchez-Borges M, Sastre-Dominguez J, Scadding GK, Scichilone N, Schmid-Grendelmeier P, Serrano E, Shields M, Siroux V, Sisul JC, Skrindo I, Smit HA, Solé D, Sooronbaev T, Spranger O, Stelmach R, Sterk PJ, Strandberg T, Sunyer J, Thijs C, Triggiani M, Valenta R, Valero A, van Eerd M, van Ganse E, van Hague M, Vandenplas O, Varona LL, Vellas B, Vezzani G, Vazankari T, Viegi G, Vontetsianos T, Wagenmann M, Walker S, Wang DY, Wahn U, Werfel T, Whalley B, Williams DM, Williams S, Wilson N, Wright J, Yawn BP, Yiallouros PK, Yusuf OM, Zaidi A, Zar HJ, Zernotti ME, Zhang L, Zhong N, Zidarn M, ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle. CLIN TRANSL ALLERGY 2016;6:47 [PubMed]
Brekelmans MP, Fens N, Brinkman P, Bos LD , Sterk PJ, Tak PP, Gerlag DM, Smelling the Diagnosis: The Electronic Nose as Diagnostic Tool in Inflammatory Arthritis. A Case-Reference Study. PLOS ONE 2016;11 (3):e0151715 [PubMed]
de Heer K, Kok MGM, Fens N, Weersink EJM, Zwinderman AH, van der Schee MPC, Visser CE, van Oers MHJ, Sterk PJ, Correction for de Heer et al., Detection of Airway Colonization by Aspergillus fumigatus by Use of Electronic Nose Technology in Patients with Cystic Fibrosis. J CLIN MICROBIOL 2016;54 (7):1926 [PubMed]
de Heer K, Kok MGM, Fens N, Weersink EJM, Zwinderman AH, van der Schee MPC, Visser CE, van Oers MHJ, Sterk PJ, Detection of Airway Colonization by Aspergillus fumigatus by Use of Electronic Nose Technology in Patients with Cystic Fibrosis. J CLIN MICROBIOL 2016;54 (3):569-575 [PubMed]
de Heer K, Vonk SI, Kok M, Kolader M, Zwinderman AH, van Oers MHJ, Sterk PJ, Visser CE, eNose technology can detect and classify human pathogenic molds in vitro: a proof-of-concept study of Aspergillus fumigatus and Rhizopus oryzae. J BREATH RES 2016;10 (3):036008 [PubMed]
den Otter I, Willems LNA, van Schadewijk A, van Wijngaarden S, Janssen K, de Jeu RC, Sont JK, Sterk PJ, Hiemstra PS, Lung function decline in asthma patients with elevated bronchial CD8, CD4 and CD3 cells. EUR RESPIR J 2016;48 (2):393-402 [PubMed]
James AJ, Reinius LE, Verhoek M, Gomes A, Kupczyk M, Hammar U, Ono J, Ohta S, Izuhara K, Bel E, Kere J, Söderhäll C, Dahlén B, Boot RG, Dahlén SE [Contributors: Gaga M, Siafakas NM, Papi A, Fabbri LM, Joos G, Brusselle G, Rabe KF, Kanniess F, Hiemstra P, Johnston SL, Chanez P, Vachier I, Gjomarkaj M, Sterk PJ, Howarth PH, Nizankowska-Mogilnicka E, Middelveld R, Holgate ST, Wilson S]] , Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease. AM J RESP CRIT CARE 2016;193 (2):131-142 [PubMed]
Kunz LIZ. Effects of inhaled corticosteroids on clinical and pathological outcomes in COPD: Insights from the GLUCOLD study. S.l.: s.n.; 2016. 204p. ISBN 9789462334366 Proefschrift Leiden University, Faculteit Geneeskunde. (Promotor(s): Hiemstra PS, Sterk PJ, Postma DS; copromotor(s): )
Leopold JH, Abu-Hanna A, Colombo C, Sterk PJ, Schultz MJ, Bos LDJ, Factors Influencing Continuous Breath Signal in Intubated and Mechanically-Ventilated Intensive Care Unit Patients Measured by an Electronic Nose. SENSORS-BASEL 2016;16 (8):1337 [PubMed]
Leusink M, Vijverberg SJH, Koenderman L, Raaijmakers JAM, de Jongste JC, Sterk PJ, Duiverman EJ, Onland-Moret NC, Postma DS, de Boer A, de Bakker PIW, Koppelman GH, Maitland-van der Zee AH, Genetic variation in uncontrolled childhood asthma despite ICS treatment. PHARMACOGENOMICS J 2016;16 (2):158-163 [PubMed]
Loymans RJB, Honkoop PJ, Termeer EH, Snoeck-Stroband JB, Assendelft WJJ, Schermer TRJ, Chung KF, Sousa AR, Sterk PJ, Reddel HK, Sont JK, ter Riet G, Identifying patients at risk for severe exacerbations of asthma: development and external validation of a multivariable prediction model. THORAX 2016;71 (9):838-846 [PubMed]
Loza MJ, Djukanovic R, Chung KF, Horowitz D, Ma K, Branigan P, Barnathan ES, Susulic VS, Silkoff PE, Sterk PJ, Baribaud F [Contributors: Adcock I, Adriaens N, Ahmed H, Aliprantis A, Alving K, Auffray C, Badorrek P, Bakke P, Balgoma D, Bansal AT, Barber C, Baribaud F, Bautmans A, Behndig AF, Bel E, Beleta J, Berglind A, Berton A, Bigler J, Bisgaard H, Bochenek G, Boedigheimer MJ, Bøonnelykke K, Brandsma J, Braun A, Brinkman P, Burg D, Campagna D, Carayannopoulos L, Caruso M, da Purificação RJPC, Chaiboonchoe A, Chaleckis R, Chanez P, Chung KF, Coleman C, Compton C, Corfield J, D'Amico A, Dahlen B, Dahlén SE, de Alba J, de Boer P, de Lepeleire I, de Meulder B, Dekker T, Delin I, Dennison P, Dijkhuis A, Djukanovic R, Draper A, Edwards J, Emma R, Ericsson M, Erpenbeck V, Erzen D, Fichtner K, Fitch N, Fleming LJ, Flood B, Fowler SJ, Frey U, Gahlemann M, Galffy G, Gallart H, Garrett T, Geiser T, Gent J, Gerhardsson dVM, Gibeon D, Gomez C, Gove K, Gozzard N, Guo YK, Hashimoto S, Haughney J, Hedlin G, Hekking PP, Henriksson E, Hewitt L, Higgenbottam T, Hoda U, Hohlfeld J, Holweg C, Horvath I, Howarth P, Hu R, Hu S, Hu X, Hudson V, James AJ, Kamphuis J, Kennington EJ, Kerry D, Klüglich M, Knobel H, Knowles R, Knox A, Kolmert J, Konradsen J, Kots M, Krueger L, Krug N, Kuo S, Kupczyk M, Lambrecht B, Lantz AS, Larsson L, Lazarinis N, Lefaudeux D, Lone-Latif S, Loza MJ, Lutter R, Marouzet L, Martin J, Masefield S, Mathon C, Matthews JG, Mazein A, Meah S, Meiser A, Menzies-Gow A, Metcalf L, Middelveld R, Mikus M, Miralpeix M, Monk P, Montuschi P, Mores N, Murray CS, Musial J, Myles D, Naz S, Nething K, Nicholas B, Nihlen U, Nilsson P, Nordlund B, Östling J, Pacino A, Pahus L, Palkonen S, Pandis I, Pavlidis S, Pennazza G, Petrén A, Pink S, Postle A, Powel P, Rahman-Amin M, Rao N, Ravanetti L, Ray E, Reinke S, Reynolds L, Riemann K, Riley J, Robberechts M, Roberts A, Roberts G, Rossios C, Rowe A, Russell K, Rutgers M, Sandström T, Santini G, Santoninco M, Schoelch C, Schofield JPR, Seibold W, Shaw DE, Sigmund R, Singer F, Sjödin M, Skipp PJ, Smids B, Smith C, Smith J, Smith KM, Söderman P, Sogbesan A, Sousa AR, Staykova D, Sterk PJ, Strandberg K, Sun K, Supple D, Szentkereszty M, Tamasi L, Tariq K, Thörngren JO, Thornton B, Thorsen J, Valente S, van Aalderen WMC, van de Pol M, van DK, van GM, Versnel J, Vestbo J, Vink A, Vissing N, von GC, Wagener A, Wagers S, Wald F, Walker S, Ward J, Weiszhart Z, Wetzel K, Wheelock CE, Wiegman C, Williams S, Wilson SJ, Woodcock A, Yang X, Yeyasingham E, Yu W, Zetterquist W, Zwinderman K]] , Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study. RESP RES 2016;17 (1):165 [PubMed]
Nassif M, Heuschen CBBC, Lu H, Bouma BJ, van Steenwijk RP, Sterk PJ, Mulder BJM, de Winter RJ, Relationship between atrial septal defects and asthma-like dyspnoea: the impact of transcatheter closure. NETH HEART J 2016;24 (11):640-646 [PubMed]
Postma DS, Wijkstra PJ, Hiemstra PS, Melgert BN, Braunstahl GJ, Hylkema MN, Sterk PJ, The Dutch National Program for Respiratory Research. LANCET RESP MED 2016;4 (5):356-357 [PubMed]
Ricciardolo FLM, Petecchia L, Sorbello V, Di Stefano A, Usai C, Massaglia GM, Gnemmi I, Mognetti B, Hiemstra PS, Sterk PJ, Sabatini F, Bradykinin B2 receptor expression in the bronchial mucosa of allergic asthmatics: the role of NF-kB. CLIN EXP ALLERGY 2016;46 (3):428-438 [PubMed]
Rootmensen G, van Keimpema A, Zwinderman A, Sterk P, Clinical phenotypes of obstructive airway diseases in an outpatient population. J ASTHMA 2016;53 (10):1026-1032 [PubMed]
Sneeboer MMS, Fens N, van de Pol MA, Majoor CJ, Meijers JCM, Kamphuisen PW, Lutter R, Sterk PJ, Bel EHD, Loss of asthma control and activation of coagulation and fibrinolysis. CLIN EXP ALLERGY 2016;46 (3):422-427 [PubMed]
Sterk PJ, Chronic diseases like asthma and COPD: do they truly exist?. EUR RESPIR J 2016;47 (2):359-361 [PubMed]
Surie S. Identification of high-risk patients and outcome in chronic thromboembolic pulmonary hypertension. S.l.: s.n.; 2016. 163p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sterk PJ; copromotor(s): Bresser P)
Thamrin C, Frey U, Kaminsky DA, Reddel HK, Seely AJE, Suki B, Sterk PJ, Systems Biology and Clinical Practice in Respiratory Medicine. The Twain Shall Meet. AM J RESP CRIT CARE 2016;194 (9):1053-1061 [PubMed]
van Ooij PJAM, Sterk PJ, van Hulst RA, Oxygen, the lung and the diver: friends and foes?. EUR RESPIR REV 2016;25 (142):496-505 [PubMed]
Wagener AH. Biomarker discovery for asthma phenotyping: From gene expression to the clinic. S.l.: s.n.; 2016. 267p. ISBN 978-94-6169-778-3 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sterk PJ, Zwinderman AH; copromotor(s): van Drunen CM)
Wildenbeest JG, van der Schee MP, Hashimoto S , Benschop KSM, Minnaar RP, Sprikkelman AB, Haarman EG, van Aalderen WMC, Sterk PJ, Pajkrt D, Wolthers KC, Prevalence of rhinoviruses in young children of an unselected birth cohort from the Netherlands. CLIN MICROBIOL INFEC 2016;22 (8):736.e9-736.e15 [PubMed]
Wilson SJ, Ward JA, Sousa AR, Corfield J, Bansal AT, de Meulder B, Lefaudeux D, Auffray C, Loza MJ, Baribaud F, Fitch N, Sterk PJ, Chung KF, Gibeon D, Sun K, Guo YK, Adcock I, Djukanovic R, Dahlen B, Chanez P, Shaw D, Krug N, Hohlfeld J, Sandström T, Howarth PH, Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study. EUR RESPIR J 2016;48 (5):1307-1319 [PubMed]
Agustí A, Antó JM, Auffray C, Barbé F, Barreiro E, Dorca J, Escarrabill J, Faner R, Furlong LI, Garcia-Aymerich J, Gea J, Lindmark B, Monsó E, Plaza V, Puhan MA, Roca J, Ruiz-Manzano J, Sampietro-Colom L, Sanz F, Serrano L, Sharpe J, Sibila O, Silverman EK, Sterk PJ, Sznajder JI, Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014. AM J RESP CRIT CARE 2015;191 (4):391-401 [PubMed]
Berger M, de Boer JD, Bresser P, van der Poll T, Lutter R, Sterk PJ, van der Zee JS, Lipopolysaccharide amplifies eosinophilic inflammation after segmental challenge with house dust mite in asthmatics. ALLERGY 2015;70 (3):257-264 [PubMed]
Bonta PI, d'Hooghe J, Sterk PJ, Bel EH, Annema JT, Reduction of Airway Smooth Muscle Mass after Bronchial Thermoplasty: Are We There Yet?. AM J RESP CRIT CARE 2015;191 (10):1207-1208 [PubMed]
Boots AW, Bos LD , van der Schee MP, van Schooten FJ, Sterk PJ, Exhaled Molecular Fingerprinting in Diagnosis and Monitoring: Validating Volatile Promises. TRENDS MOL MED 2015;21 (10):633-644 [PubMed]
Boshuizen M, Leopold JH, Zakharkina T, Knobel HH, Weda H, Nijsen TME, Vink TJ, Sterk PJ, Schultz MJ, Bos LDJ [Contributors: Cremer OL, Klein Klouwenberg PMC, Ong DSY, Frencken JF, Bonten MJM, Horn J, Juffermans N, van Hooijdonk RTM, Huson MA, Schouten LRA, Straat M, van Vught LA, Wiewel MA, Witteveen E, Glas GJ, de Beer FM, Wieske L, van der Poll T]] , Levels of cytokines in broncho-alveolar lavage fluid, but not in plasma, are associated with levels of markers of lipid peroxidation in breath of ventilated ICU patients. J BREATH RES 2015;9 (3):036010 [PubMed]
Bruning AHL, Thomas XV, van der Linden L, Wildenbeest JG, Minnaar RP, Jansen RR, de Jong MD, Sterk PJ, van der Schee MP, Wolthers KC, Pajkrt D, Clinical, virological and epidemiological characteristics of rhinovirus infections in early childhood: A comparison between non-hospitalised and hospitalised children. J CLIN VIROL 2015;73:120-126 [PubMed]
de Vries R, Brinkman P, van der Schee MP, Fens N, Dijkers E, Bootsma SK, de Jongh FHC, Sterk PJ, Integration of electronic nose technology with spirometry: validation of a new approach for exhaled breath analysis. J BREATH RES 2015;9 (4):046001 [PubMed]
Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, Benn M, Nielsen SF, Dahl M, Verschuren WM, Picavet HSJ, Smit HA, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat Me, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJM, Timens W, Boezen HM, Postma DS, Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study (vol 9, e91621, 2014). PLOS ONE 2015;10 (5):e0129524 [PubMed]
Fens N, van der Sluijs KF, van de Pol MA, Dijkhuis A, Smids BS, van der Zee JS, Lutter R, Zwinderman AH, Sterk PJ [Contributors: Berger M, Yick D, Wagener A, Amelink M, Reesink H, Bresser P, Kunst P, Venekamp L, Majoor C, van Steenwijk R, Jonkers R]] , Electronic Nose Identifies Bronchoalveolar Lavage Fluid Eosinophils in Asthma. AM J RESP CRIT CARE 2015;191 (9):1086-1088 [PubMed]
Fleming L, Murray C, Bansal AT, Hashimoto S, Bisgaard H, Bush A, Frey U, Hedlin G, Singer F, van Aalderen WM, Vissing NH, Zolkipli Z, Selby A, Fowler S, Shaw D, Chung KF, Sousa AR, Wagers S, Corfield J, Pandis I, Rowe A, Formaggio E, Sterk PJ, Roberts G [Contributors: Tariq K, Dennison P, Behndig AF, van Aalderen W, Lutter R, Wagener A, van Drunen K, Hekking PP, Brinkman P, Zwinderman K, Mores N, Santini G, Valente S, Rossios C, Gibeon D, Hoda U, Rocha JPCdP, Sogbesan A, Gent J, Menzies-Gow A, Campagna D, Bigler J, Boedigheimer MJ, Yu W, Hu X, Fichtner K, Nething K, Erzen D, Sigmund R, Riemann K, Berton A, Klüglich M, Gahlemann M, Hohlfeld J, Badorrek P, Faulenbach C, James A, Henriksson E, Middelveld R, Lantz AS, Strandberg K, Galffy G, Szentkereszty M, Tamasi L, Smith KM, de Meulder B, Lefaudeux D, Berglind A, Konradsen JR, Bønnelykke K, Vissing NH, Stokholm J, Kerry G, Lowe L, Johnson K, Stephan S, Sunthar M, Guillmant-Farry E, Nsubuga S]] , The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts. EUR RESPIR J 2015;46 (5):1322-1333 [PubMed]
Hofstra JJ, Matamoros S, van de Pol MA, de Wever B, Tanck MW, Wendt-Knol H, Deijs M, van der Hoek L, Wolthers KC, Molenkamp R, Visser CE, Sterk PJ, Lutter R, de Jong MD, Changes in microbiota during experimental human Rhinovirus infection. BMC INFECT DIS 2015;15:336 [PubMed]
Honkoop PJ, Loijmans RJB, Termeer EH, Snoeck-Stroband JB, van den Hout WB, Bakker MJ, Assendelft WJJ, ter Riet G, Sterk PJ, Schermer TRJ, Sont JK, Symptom- and fraction of exhaled nitric oxide-driven strategies for asthma control: A cluster-randomized trial in primary care. J ALLERGY CLIN IMMUN 2015;135 (3):682-8.e11 [PubMed]
Hubers AJ, Heideman DAM, Burgers SA, Herder GJM, Sterk PJ, Rhodius RJ , Smit HJ, Krouwels F, Welling A, Witte BI, Duin S, Koning R, Comans EFI, Steenbergen RDM, Postmus PE, Meijer GA, Snijders PJF, Smit EF, Thunnissen E, DNA hypermethylation analysis in sputum for the diagnosis of lung cancer: training validation set approach. BRIT J CANCER 2015;112 (6):1105-1113 [PubMed]
Korevaar DA, Westerhof GA, Wang J, Cohen JF, Spijker R, Sterk PJ, Bel EH, Bossuyt PMM, Diagnostic accuracy of minimally invasive markers for detection of airway eosinophilia in asthma: a systematic review and meta-analysis. LANCET RESP MED 2015;3 (4):290-300 [PubMed]
Kunz LIZ, Postma DS, Klooster K, Lapperre TS, Vonk JM, Sont JK, Kerstjens HAM, Snoeck-Stroband JB, Hiemstra PS, Sterk PJ [Contributors: Kauffman HF, de Reus D, Boezen HM, Jansen DF, Vonk JM, Barentsen MDW, Timens W, Zeinstra-Smit M, Luteijn AJ, van der Molen T, ter Veen G, Gosman MME, ten Hacken NHT, Kerstjens HAM, van Maaren MS, Postma DS, Veltman CA, Verbokkem A, Verhage I, Klooster K, Thiadens HA, Snoeck-Stroband JB, Sont JK, Gast-Strookman J, Hiemstra PS, Janssen K, Rabe KF, van Schadewijk A, Schrumpf JA, Smit-Bakker J, Stolk J, Tire ACJA, van der Veen H, Wijffels MME, Willems LNA, Sterk PJ, Lapperre TS, Mauad T]] , Relapse in FEV1 Decline After Steroid Withdrawal in COPD. CHEST 2015;148 (2):389-396 [PubMed]
Kunz LIZ, van't Wout EFA, van Schadewijk A, Postma DS, Kerstjens HAM, Sterk PJ, Hiemstra PS, Regulation of YKL-40 expression by corticosteroids: effect on pro-inflammatory macrophages in vitro and its modulation in COPD in vivo. RESP RES 2015;16:154 [PubMed]
Leopold JH, Bos LDJ, Sterk PJ, Schultz MJ, Fens N, Horvath I, Bikov A, Montuschi P, Di Natale C, Yates DH, Abu-Hanna A, Comparison of classification methods in breath analysis by electronic nose. J BREATH RES 2015;9 (4):046002 [PubMed]
Shaw DE, Sousa AR, Fowler SJ, Fleming LJ, Roberts G, Corfield J, Pandis I, Bansal AT, Bel EH, Auffray C, Compton CH, Bisgaard H, Bucchioni E, Caruso M, Chanez P, Dahlén B, Dahlen SE, Dyson K, Frey U, Geiser T, Gerhardsson de Verdier M, Gibeon D, Guo YK, Hashimoto S, Hedlin G, Jeyasingham E, Hekking PPW, Higenbottam T, Horváth I, Knox AJ, Krug N, Erpenbeck VJ, Larsson LX, Lazarinis N, Matthews JG, Middelveld R, Montuschi P, Musial J, Myles D, Pahus L, Sandström T, Seibold W, Singer F, Strandberg K, Vestbo J, Vissing N, von Garnier C, Adcock IM, Wagers S, Rowe A, Howarth P, Wagener AH , Djukanovic R, Sterk PJ, Chung KF [Contributors: Tariq K, Dennison P, Behndig AF, van Aalderen W, Lutter R, Wagener A, van Drunen K, Hekking PP, Brinkman P, Zwinderman K, Mores N, Santini G, Valente S, Rossios C, Gibeon D, Hoda U, Rocha JPCdP, Sogbesan A, Gent J, Menzies-Gow A, Campagna D, Bigler J, Boedigheimer MJ, Yu W, Hu X, Fichtner K, Nething K, Erzen D, Sigmund R, Gahlemann M, Riemann K, Berton A, Klüglich M, Hohlfeld J, Badorrek P, Faulenbach C, James A, Lantz AS, Henriksson E, Middelveld R, Strandberg K, Galffy G, Szentkereszty M, Smith KM, Tamasi L, de Meulder B, Lefaudeux D, Adcock IM, Ahmed H, Allen D, Auffray C, Badorrek P, Ballereau S, Bansal AT, Behndig AF, Bel EH, Berglind A, Berton A, Bigler J, Bisgaard H, Boedigheimer MJ, Brinkman P, Bucchioni E, Bush A, Bønnelykke K, Chaiboonchoe A, Campagna D, Caruso M, Casaulta C, Chanez P, Chung KF, Compton CH, Corfield J, Dahlen SE, Dahlén B, de Meulder B, Delin I, Dennison P, Djukanovic R, Dyson K, El Hadjam L, Erpenbeck VJ, Erzen D, Faulenbach C, Fichtner K, Fitch N, Fleming LJ, Formaggio E, Fowler SJ, Frey U, Gahlemann M, Galffy G, Garissi D, Garret T, Geiser T, Gerhardsson de Verdier M, von Garnier C, Gibeon D, Guillmnt-Farry E, Guo Y, Hashimoto S , Hedlin G, Hekking PW, Henriksson E, Higenbottam T, Hoda U, Horváth I, Howarth P, Hu X, James A, Jeyasingham E, Johnston K, Jullian N, Kerry G, Klüglich M, Knox AJ, Konradsen JR, Krueger L, Krug N, Larsson LX, Latzin P, Lazarinis N, Lefaudeux D, Lemonnier N, Lutter R, Mazein A, McEvoy L, Menzies-Gow A, Middelveld RJM, Montuschi P, Mores N, Murray CS, Musial J, Myles D, Nething K, Nihlén U, Niven R, Nordlund B, Nsubuga S, Pahus L, Pandis I, Pellet J, Pison C, Praticò G, Puig Valls M, Riemann K, Roberts G, Rocha JP, Rossios C, Rowe A, Sandström T, Santini G, Saqi M, Scott S, Sehgal N, Seibold W, Shaw DE, Sigmund R, Singer F, Sogbesan A, Sousa AR, Söderman P, Spycher F, Stephan S, Sterk PJ, Stokholm J, Strandberg K, Sunthar S, Tamasi L, Tariq K, Valente S, van Aalderen WM, van Drunen CM, Vestbo J, Vissing NH, Vyas A, Wagener AH, Wagers SS, Wilson SJ, Yu W, Zetterquist W, Zolkipli Z, Zwinderman AH, Prins JB, Visintin L, Evans H, Puhl M, Buzermaniene L, Hudson V, Bond L, de Boer P, Widdershoven G, Roberts A, Supple D, Hamerlijnck D, Negus J, Kamphuis J, Sergison L, Onstein S, MacNee W, Bernardini R, Bont L, Wecksell PA]] , Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort. EUR RESPIR J 2015;46 (5):1308-1321 [PubMed]
Snoeck-Stroband JB, Lapperre TS, Sterk PJ, Hiemstra PS, Thiadens HA, Boezen HM, ten Hacken NHT, Kerstjens HAM, Postma DS, Timens W, Sont JK, Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial. PLOS ONE 2015;10 (12):e0143793 [PubMed]
van der Schee MPC. The volatile metabolome and microbiome in pulmonary and gastro-intestinal disease. S.l.: s.n.; 2015. 261p. ISBN 9789462950825 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sterk PJ, van Aalderen WMC; copromotor(s): Haarman EG, Sprikkelman AB)
van der Schee MP, Hashimoto S, Schuurman AC, van Driel JSR, Adriaens N, van Amelsfoort RM, Snoeren T, Regenboog M, Sprikkelman AB, Haarman EG, van Aalderen WMC, Sterk PJ, Altered exhaled biomarker profiles in children during and after rhinovirus-induced wheeze. EUR RESPIR J 2015;45 (2):440-448 [PubMed]
van der Schee MP, Paff T, Brinkman P, van Aalderen WMC, Haarman EG, Sterk PJ, Breathomics in lung disease. CHEST 2015;147 (1):224-231 [PubMed]
Wagener AH, de Nijs SB, Lutter R, Sousa AR, Weersink EJM, Bel EH, Sterk PJ, External validation of blood eosinophils, FE(NO) and serum periostin as surrogates for sputum eosinophils in asthma. THORAX 2015;70 (2):115-120 [PubMed]
Amelink M, Hashimoto S, Spinhoven P, Pasma HR, Sterk PJ, Bel EH, ten Brinke A, Anxiety, depression and personality traits in severe, prednisone-dependent asthma. RESP MED 2014;108 (3):438-444 [PubMed]
Bos LDJ. Diagnosis of pulmonary injury and infection by exhaled breath analysis. S.l.: s.n.; 2014. 276p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Schultz MJ, Sterk PJ; copromotor(s): )
Bos LDJ, de Jong MD, Sterk PJ, Schultz MJ, How integration of global omics-data could help preparing for pandemics - a scent of influenza. FRONT GENET 2014;5:UNSP 80 [PubMed]
Bos LDJ, Martin-Loeches I, Kastelijn JB, Gili G, Espasa M, Povoa P, Kolk AHJ, Janssen HG, Sterk PJ, Artigas A, Schultz MJ, The volatile metabolic fingerprint of ventilator-associated pneumonia. INTENS CARE MED 2014;40 (5):761-762 [PubMed]
Bos LDJ, Schultz MJ, Sterk PJ, Exhaled breath profiling for diagnosing acute respiratory distress syndrome. BMC PULM MED 2014;14 (1):72 [PubMed]
Bos LDJ, Wang Y, Weda H, Nijsen TME, Janssen APGE, Knobel HH, Vink TJ, Schultz MJ, Sterk PJ, A simple breath sampling method in intubated and mechanically ventilated critically ill patients. RESP PHYSIOL NEUROBI 2014;191:67-74 [PubMed]
Bos LDJ, Weda H, Wang Y, Knobel HH, Nijsen TME, Vink TJ, Zwinderman AH, Sterk PJ, Schultz MJ, Exhaled breath metabolomics as a noninvasive diagnostic tool for acute respiratory distress syndrome. EUR RESPIR J 2014;44 (1):188-197 [PubMed]
Bousquet J, Addis A, Adcock I, Agache I, Agusti A, Alonso A, Annesi-Maesano I, Anto JM, Bachert C, Baena-Cagnani CE, Bai C, Baigenzhin A, Barbara C, Barnes PJ, Bateman ED, Beck L, Bedbrook A, Bel EH, Benezet O, Bennoor KS, Benson M, Bernabeu-Wittel M, Bewick M, Bindslev-Jensen C, Blain H, Blasi F, Bonini M, Bonini S, Boulet LP, Bourdin A, Bourret R, Bousquet PJ, Brightling CE, Briggs A, Brozek J, Buhl R, Bush A, Caimmi D, Calderon M, Calverley P, Camargos PA, Camuzat T, Canonica GW, Carlsen KH, Casale TB, Cazzola M, Cepeda Sarabia AM, Cesario A, Chen YZ, Chkhartishvili E, Chavannes NH, Chiron R, Chuchalin A, Chung KF, Cox L, Crooks G, Crooks MG, Cruz AA, Custovic A, Dahl R, Dahlen SE, de Blay F, Dedeu T, Deleanu D, Demoly P, Devillier P, Didier A, Dinh-Xuan AT, Djukanovic R, Dokic D, Douagui H, Dubakiene R, Eglin S, Elliot F, Emuzyte R, Fabbri L, Fink Wagner A, Fletcher M, Fokkens WJ, Fonseca J, Franco A, Frith P, Furber A, Gaga M, Garcés J, Garcia-Aymerich J, Gamkrelidze A, Gonzales-Diaz S, Gouzi F, Guzmán MA, Haahtela T, Harrison D, Hayot M, Heaney LG, Heinrich J, Hellings PW, Hooper J, Humbert M, Hyland M, Iaccarino G, Jakovenko D, Jardim JR, Jeandel C, Jenkins C, Johnston SL, Jonquet O, Joos G, Jung KS, Kalayci O, Karunanithi S, Keil T, Khaltaev N, Kolek V, Kowalski ML, Kull I, Kuna P, Kvedariene V, Le LT, Lodrup Carlsen KC, Louis R, MacNee W, Mair A, Majer I, Manning P, de Manuel Keenoy E, Masjedi MR, Melen E, Melo-Gomes E, Menzies-Gow A, Mercier G, Mercier J, Michel JP, Miculinic N, Mihaltan F, Milenkovic B, Molimard M, Momas I, Montilla-Santana A, Morais-Almeida M, Morgan M, N'Diaye M, Nafti S, Nekam K, Neou A, Nicod L, O'Hehir R, Ohta K, Paggiaro P, Palkonen S, Palmer S, Papadopoulos NG, Papi A, Passalacqua G, Pavord I, Pigearias B, Plavec D, Postma DS, Price D, Rabe KF, Radier Pontal F, Redon J, Rennard S, Roberts J, Robine JM, Roca J, Roche N, Rodenas F, Roggeri A, Rolland C, Rosado-Pinto J, Ryan D, Samolinski B, Sanchez-Borges M, Schünemann HJ, Sheikh A, Shields M, Siafakas N, Sibille Y, Similowski T, Small I, Sola-Morales O, Sooronbaev T, Stelmach R, Sterk PJ, Stiris T, Sud P, Tellier V, To T, Todo-Bom A, Triggiani M, Valenta R, Valero AL, Valiulis A, Valovirta E, van Ganse E, Vandenplas O, Vasankari T, Vestbo J, Vezzani G, Viegi G, Visier L, Vogelmeier C, Vontetsianos T, Wagstaff R, Wahn U, Wallaert B, Whalley B, Wickman M, Williams DM, Wilson N, Yawn BP, Yiallouros PK, Yorgancioglu A, Yusuf OM, Zar HJ, Zhong N, Zidarn M, Zuberbier T, Integrated care pathways for airway diseases (AIRWAYS-ICPs). EUR RESPIR J 2014;44 (2):304-323 [PubMed]
Bousquet J, Jorgensen C, Dauzat M, Cesario A, Camuzat T, Bourret R, Best N, Anto JM, Abecassis F, Aubas P, Avignon A, Badin M, Bedbrook A, Blain H, Bourdin A, Bringer J, Camu W, Cayla G, Costa DJ, Courtet P, Cristol JP, Demoly P, de la Coussaye JE, Fesler P, Gouzi F, Gris JC, Guillot B, Hayot M, Jeandel C, Jonquet O, Journot L, Lehmann S, Mathieu G, Morel J, Ninot G, Pelissier J, Picot MC, Radier-Pontal F, Robine JM, Rodier M, Roubille F, Sultan A, Wojtusciszyn A, Auffray C, Balling R, Barbara C, Cambon-Thomsen A, Chavannes NH, Chuchalin A, Crooks G, Dedeu A, Fabbri LM, Garcia-Aymerich J, Hajjam J, Melo Gomes E, Palkonen S, Piette F, Pison C, Price D, Samolinski B, Schunemann HJ, Sterk PJ, Yiallouros P, Roca J, van de Perre P, Mercier J, Systems medicine approaches for the definition of complex phenotypes in chronic diseases and ageing. From concept to implementation and policies. CURR PHARM DESIGN 2014;20 (38):5928-5944 [PubMed]
Cesario A, Auffray C, Agusti A, Apolone G, Balling R, Barbanti P, Bellia A, Boccia S, Bousquet J, Cardaci V, Cazzola M, Dall'Armi V, Daraselia N, Ros LD, Bufalo AD, Ducci G, Ferri L, Fini M, Fossati C, Gensini G, Granone PM, Kinross J, Lauro D, Cascio GL, Lococo F, Lococo A, Maier D, Marcus F, Margaritora S, Marra C, Minati G, Neri M, Pasqua F, Pison C, Pristipino C, Roca J, Rosano G, Rossini PM, Russo P, Salinaro G, Shenhar S, Soreq H, Sterk PJ, Stocchi F, Torti M, Volterrani M, Wouters EFM, Frustaci A, Bonassi S, A systems medicine clinical platform for understanding and managing non- communicable diseases. CURR PHARM DESIGN 2014;20 (38):5945-5956 [PubMed]
Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, Adcock IM, Bateman ED, Bel EH, Bleecker ER, Boulet LP, Brightling C, Chanez P, Dahlen SE, Djukanovic R, Frey U, Gaga M, Gibson P, Hamid Q, Jajour NN, Mauad T, Sorkness RL, Teague WG, International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. EUR RESPIR J 2014;43 (2):343-373 [PubMed]
Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, Benn M, Nielsen SF, Dahl M, Verschuren WM, Picavet HSJ, Smit HA, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat MA, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJM, Timens W, Boezen HM, Postma DS [Contributors: Alizadeh BZ, de Boer RA, Boezen HM, Bruinenberg M, Franke L, van der Harst P, Hillege HL, van der Klauw MM, Navis G, Ormel J, Postma DS, Rosmalen JGM, Slaets JP, Snieder H, Stolk RP, Wolffenbuttel BHR, Wijmenga C]] , Susceptibility to chronic mucus hypersecretion, a genome wide association study. PLOS ONE 2014;9 (4):e91621 [PubMed]
Gustafsson M, Nestor CE, Zhang H, Barabási AL, Baranzini S, Brunak S, Chung KF, Federoff HJ, Gavin AC, Meehan RR, Picotti P, Pujana MÀ, Rajewsky N, Smith KG, Sterk PJ, Villoslada P, Benson M, Modules, networks and systems medicine for understanding disease and aiding diagnosis. GENOME MED 2014;6 (10):82 [PubMed]
Hoonhorst SJM, ten Hacken NHT, Vonk JM, Timens W, Hiemstra PS, Lapperre TS, Sterk PJ, Postma DS, Steroid resistance in COPD? Overlap and differential anti-inflammatory effects in smokers and ex-smokers. PLOS ONE 2014;9 (2):e87443 [PubMed]
Hubers AJ, Brinkman P, Boksem RJ, Rhodius RJ, Witte BI, Zwinderman AH, Heideman DAM, Duin S, Koning R, Steenbergen RDM, Snijders PJF, Smit EF, Sterk PJ, Thunnissen E, Combined sputum hypermethylation and eNose analysis for lung cancer diagnosis. J CLIN PATHOL 2014;67 (8):707-711 [PubMed]
Kupczyk M, Dahlén B, Sterk PJ, Nizankowska-Mogilnicka E, Papi A, Bel EH, Chanez P, Howarth PH, Holgate ST, Brusselle G, Siafakas NM, Gjomarkaj M, Dahlén SE [Contributors: Weersink E, Gaga M, Papadopoulos N, Oikonomidou E, Zervas E, Contoli M, Pauwels RA, Joos GF, de Rudder I, Schelfhout V, Richter K, Gerding D, Magnussen H, Samara K, Plataki M, Papadopouli E, Szczeklik A, Ziolkowska- Graca B, Kania A, Gawlewicz-Mroczka A, Duplaga M, Figiel E, Rabe KF, Gauw S, van Veen I, Kips JC, Johnston SL, Mallia P, Campbell DA, Robinson DS, Kanniess F, Fabbri LM, Romagnoli M, Vachier I, Devautour C, Meziane L, Vignola AM, Pace E, Profita M, Wilson SJ, Hewitt L, Holoway J, JM Middelveld R, Damm K, Delin I, Eduards M, Ek A, Ekström T, Gaber F, Gülich A, James A, Johansson LE, Karlsson Ö, Kumlin M, Martling I, Olsson M, Skedinger M, Haque S, Hiemstra PS]] , Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma. ALLERGY 2014;69 (9):1198-1204 [PubMed]
Kupczyk M, ten Brinke A, Sterk PJ, Bel EH, Papi A, Chanez P, Nizankowska-Mogilnicka E, Gjomarkaj M, Gaga M, Brusselle G, Dahlén B, Dahlén SE [Contributors: Weersink E, Papadopoulos N, Oikonomidou E, Zervas E, Contoli M, Pauwels RA, Joos GF, de Rudder I, Schelfhout V, Richter K, Gerding D, Magnussen H, Siafakas NM, Tzortzaki E, Samara K, Plataki M, Papadopouli E, Szczeklik A, Ziolkowska-Graca B, Kania A, Gawlewicz-Mroczka A, Duplaga M, Figiel E, Rabe KF, Hiemstra PS, Gauw S, van Veen I, Kips JC, Johnston SL, Mallia P, Campbell DA, Robinson DS, Kanniess F, Fabbri LM, Romagnoli M, Vachier I, Devautour C, Meziane L, Vignola AM, Pace E, Profita M, Holgate ST, Howarth PH, Wilson SJ, Hewitt L, Holoway J, Middelveld RJM, Damm K, Delin I, Eduards M, Ek A, Ekström T, Gaber F, Gülich A, James A, Johansson LE, Karlsson O, Kumlin M, Martling I, Olsson M, Skedinger M, Haque S]] , Frequent exacerbators--a distinct phenotype of severe asthma. CLIN EXP ALLERGY 2014;44 (2):212-221 [PubMed]
Leopold JH, van Hooijdonk RTM, Sterk PJ, Abu-Hanna A, Schultz MJ, Bos LDJ, Glucose prediction by analysis of exhaled metabolites - a systematic review. BMC ANESTHESIOL 2014;14:46 [PubMed]
Loymans RJB, Gemperli A, Cohen J, Rubinstein SM, Sterk PJ, Reddel HK, Jüni P, ter Riet G, Comparative effectiveness of long term drug treatment strategies to prevent asthma exacerbations: network meta-analysis. BMJ-BRIT MED J 2014;348:g3009 [PubMed]
Majoor CJ , van de Pol MA, Kamphuisen PW, Meijers JCM, Molenkamp R, Wolthers KC, van der Poll T, Nieuwland R, Johnston SL, Sterk PJ, Bel EHD, Lutter R, van der Sluijs KF, Evaluation of coagulation activation after rhinovirus infection in patients with asthma and healthy control subjects: an observational study. RESP RES 2014;15 (1):14 [PubMed]
Sterk PJ, Lutter R, Asthma phenotyping: TH2-high, TH2-low, and beyond. J ALLERGY CLIN IMMUN 2014;133 (2):395-396 [PubMed]
van den Berge M, Steiling K, Timens W, Hiemstra PS, Sterk PJ, Heijink IH, Liu G, Alekseyev YO, Lenburg ME, Spira A, Postma DS, Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity. THORAX 2014;69 (1):14-23 [PubMed]
van Ooij PJAM, van Hulst RA, Houtkooper A, Sterk PJ, Nitric oxide and carbon monoxide diffusing capacity after a 1-h oxygen dive to 9 m of sea water. CLIN PHYSIOL FUNCT I 2014;34 (3):199-208 [PubMed]
van Ooij PJAM, van Hulst RA, Kulik W, Brinkman P, Houtkooper A, Sterk PJ, Hyperbaric oxygen diving affects exhaled molecular profiles in men. RESP PHYSIOL NEUROBI 2014;198:20-24 [PubMed]
Wagener AH , Zwinderman AH, Luiten S, Fokkens WJ, Bel EH, Sterk PJ, van Drunen CM, dsRNA-induced changes in gene expression profiles of primary nasal and bronchial epithelial cells from patients with asthma, rhinitis and controls. RESP RES 2014;15 (1):9 [PubMed]
Wlodzimirow KA, Abu-Hanna A, Schultz MJ, Maas MAW, Bos LDJ, Sterk PJ, Knobel HH, Soers RJT, Chamuleau RAFM, Exhaled breath analysis with electronic nose technology for detection of acute liver failure in rats. BIOSENS BIOELECTRON 2014;53:129-134 [PubMed]
Yick CY, Zwinderman AH, Kunst PW, Grünberg K, Mauad T, Chowdhury S, Bel EH, Baas F, Lutter R, Sterk PJ, Gene expression profiling of laser microdissected airway smooth muscle tissue in asthma and atopy. ALLERGY 2014;69 (9):1233-1240 [PubMed]
Amelink M, de Groot JC, de Nijs SB, Lutter R, Zwinderman AH, Sterk PJ, ten Brinke A, Bel EH, Severe adult-onset asthma: A distinct phenotype. J ALLERGY CLIN IMMUN 2013;132 (2):336-341 [PubMed]
Amelink M, de Nijs SB, de Groot JC, van Tilburg PMB, van Spiegel PI, Krouwels FH, Lutter R, Zwinderman AH, Weersink EJM, ten Brinke A, Sterk PJ, Bel EH, Three phenotypes of adult-onset asthma. ALLERGY 2013;68 (5):674-680 [PubMed]
Bos LDJ, Sterk PJ, Schultz MJ, Volatile metabolites of pathogens: a systematic review. PLOS PATHOG 2013;9 (5):e1003311 [PubMed]
Bos LDJ, van Walree IC, Kolk AHJ, Janssen HG, Sterk PJ, Schultz MJ, Alterations in exhaled breath metabolite-mixtures in two rat models of lipopolysaccharide-induced lung injury. J APPL PHYSIOL 2013;115 (10):1487-1495 [PubMed]
Burrowes KS, de Backer J, Smallwood R, Sterk PJ, Gut I, Wirix-Speetjens R, Siddiqui S, Owers-Bradley J, Wild J, Maier D, Brightling C, Multi-scale computational models of the airways to unravel the pathophysiological mechanisms in asthma and chronic obstructive pulmonary disease (AirPROM). INTERFACE FOCUS 2013;3 (2):20120057 [PubMed]
Carraro S, Giordano G, Reniero F, Carpi D, Stocchero M, Sterk PJ, Baraldi E, Asthma severity in childhood and metabolomic profiling of breath condensate. ALLERGY 2013;68 (1):110-117 [PubMed]
de Heer K, van der Schee MP, Zwinderman K, van den Berk IAH, Visser CE, van Oers R, Sterk PJ, Electronic nose technology for detection of invasive pulmonary aspergillosis in prolonged chemotherapy-induced neutropenia: a proof-of-principle study. J CLIN MICROBIOL 2013;51 (5):1490-1495 [PubMed]
Diamant Z, Gauvreau GM, Cockcroft DW, Boulet LP, Sterk PJ, de Jongh FHC, Dahlén B, O'Byrne PM, Inhaled allergen bronchoprovocation tests. J ALLERGY CLIN IMMUN 2013;132 (5):1045-1055.e6 [PubMed]
Dragonieri S, Brinkman P, Mouw E, Zwinderman AH, Carratú P, Resta O, Sterk PJ, Jonkers RE, An electronic nose discriminates exhaled breath of patients with untreated pulmonary sarcoidosis from controls. RESP MED 2013;107 (7):1073-1078 [PubMed]
Fens N, van der Schee MP, Brinkman P, Sterk PJ, Exhaled breath analysis by electronic nose in airways disease. Established issues and key questions. CLIN EXP ALLERGY 2013;43 (7):705-715 [PubMed]
Fens N, van Rossum AGJ, Zanen P, van Ginneken B, van Klaveren RJ, Zwinderman AH, Sterk PJ, Subphenotypes of mild-to-moderate COPD by factor and cluster analysis of pulmonary function, CT imaging and breathomics in a population-based survey. COPD 2013;10 (3):277-285 [PubMed]
Gauw SA, Fens N, Knobel HH, de Bokx PK, Pronk P, Gaastra MTW, Mooij MC, van Vlijmen-van Keulen CJ, Sterk PJ, Analysing exhaled breath during endovenous laser ablation of varicose veins using an electronic nose and gas chromatography-mass spectrometry. PHLEBOLOGY 2013;28 (2):114-116 [PubMed]
Kunz LIZ, Strebus J, Budulac SE, Lapperre TS, Sterk PJ, Postma DS, Mauad T, Timens W, Hiemstra PS [Contributors: Kauffman HF, de Reus D, Boezen HM, Jansen DF, Vonk JM, Barentsen MDW, Timens W, Zeinstra-Smit M, Luteijn AJ, van der Molen T, ter Veen G, Gosman MME, ten Hacken NHT, Kerstjens HAM, van Maaren MS, Postma DS, Veltman CA, Verbokkem A, Verhage I, Vink-Klooster HK, Thiadens HA, Snoeck-Stroband JB, Sont JK, Gast-Strookman J, Hiemstra PS, Janssen K, Lapperre TS, Rabe KF, van Schadewijk A, Schrumpf JA, Smit-Bakker J, Sterk PJ, Stolk J, Tiré ACJA, van der Veen H, Wijffels MME, Willems LNA, Mauad T]] , Inhaled steroids modulate extracellular matrix composition in bronchial biopsies of COPD patients: a randomized, controlled trial. PLOS ONE 2013;8 (5):e63430 [PubMed]
Kupczyk M, Haque S, Sterk PJ, Niżankowska-Mogilnicka E, Papi A, Bel EH, Chanez P, Dahlén B, Gaga M, Gjomarkaj M, Howarth PH, Johnston SL, Joos GF, Kanniess F, Tzortzaki E, James A, Middelveld RJM, Dahlén SE [Contributors: Weersink E, Papadopoulos N, Oikonomidou E, Zervas E, Contoli M, Pauwels RA, Brusselle G, de Rudder I, Schelfhout V, Richter K, Gerding D, Magnussen H, Siafakas NM, Samara K, Plataki M, Papadopouli E, Szczeklik A, Ziolkowska-Graca B, Kania A, Gawlewicz-Mroczka A, Duplaga M, Figiel E, Rabe KF, Hiemstra PS, Gauw S, van Veen I, Kips JC, Mallia P, Campbell DA, Robinson DS, Fabbri LM, Romagnoli M, Vachier I, Devautour C, Meziane L, Maurizio Vignola A, Pace E, Profita M, Holgate ST, Wilson SJ, Hewitt L, Holoway J, Damm K, Delin I, Eduards M, Ek A, Ekström T, Gülich A, Johansson LE, Karlsson O, Kumlin M, Martling I, Skedinger M]] , Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study. THORAX 2013;68 (7):611-618 [PubMed]
Majoor CJ , Kamphuisen PW, Zwinderman AH, ten Brinke A, Amelink M, Rijssenbeek-Nouwens L, Sterk PJ, Büller HR, Bel EH, Risk of deep vein thrombosis and pulmonary embolism in asthma. EUR RESPIR J 2013;42 (3):655-661 [PubMed]
Nuijsink M, Hop WCJ, Jongste JCd, Sterk PJ, Duiverman AEJ [Contributors: Nuijsink M, Kouwenberg JM, Hop WCJ, Sterk PJ, Rikkers-Mutsaerts ERVM, Duiverman EJ, de Jongste JC, van der Baan-Slootweg OH, van Essen-Zandvliet EEM, van den Berg NJ, Boogaard JM, Brand PLP, Kamps AWA, Brinkhorst G, Dankert-Roelse JE, Nagelkerke AF, van Gent R, Heijnens JWCM, Hendriks JJE, Jöbsis Q, van der Laag J, Brackel HJL, Van Nierop JC , Vaessen-Verberne AAPH]] , Perception of bronchoconstriction: a complementary disease marker in children with asthma. J ASTHMA 2013;50 (6):560-564 [PubMed]
Nuijsink M, Hop WCJ, Sterk PJ, Duiverman EJ, de Jongste JC, Urinary eosinophil protein X in childhood asthma: relation with changes in disease control and eosinophilic airway inflammation. MEDIAT INFLAMM 2013;2013:532619 [PubMed]
Nuijsink M, Vaessen-Verberne AAPH, Hop WCJ, Sterk PJ, Duiverman EJ, de Jongste JC, Long-term follow-up after two years of asthma treatment guided by airway responsiveness in children. RESP MED 2013;107 (7):981-986 [PubMed]
Paff T, van der Schee MP, Daniels JMA, Pals G, Postmus PE, Sterk PJ, Haarman EG, Exhaled molecular profiles in the assessment of cystic fibrosis and primary ciliary dyskinesia. J CYST FIBROS 2013;12 (5):454-460 [PubMed]
Ravensberg AJ, Slats AM, van Wetering S, Janssen K, van Wijngaarden S, de Jeu R, Rabe KF, Sterk PJ, Hiemstra PS, CD8(+) T cells characterize early smoking-related airway pathology in patients with asthma. RESP MED 2013;107 (7):959-966 [PubMed]
Sabatini F, Luppi F, Petecchia L, Stefano AD, Longo AM, Eva A, Vanni C, Hiemstra PS, Sterk PJ, Sorbello V, Fabbri LM, Rossi GA, Ricciardolo FLM, Bradykinin-induced asthmatic fibroblast/myofibroblast activities via bradykinin B2 receptor and different MAPK pathways. EUR J PHARMACOL 2013;710 (1-3):100-109 [PubMed]
Steiling K, van den Berge M, Hijazi K, Florido R, Campbell J, Liu G, Xiao J, Zhang X, Duclos G, Drizik E, Si H, Perdomo C, Dumont C, Coxson HO, Alekseyev YO, Sin D, Pare P, Hogg JC, McWilliams A, Hiemstra PS, Sterk PJ, Timens W, Chang JT, Sebastiani P, O'Connor GT, Bild AH, Postma DS, Lam S, Spira A, Lenburg ME, A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. AM J RESP CRIT CARE 2013;187 (9):933-942 [PubMed]
Sterk PJ, Fens N, Carpagnano GE, Wake-up call by breathomics in sleep apnoea. EUR RESPIR J 2013;42 (1):1-4 [PubMed]
Sterk PJ, Ricciardolo FLM, Clinical-biological phenotyping beyond inflammation in asthma delivers. AM J RESP CRIT CARE 2013;187 (2):117-118 [PubMed]
Sterk PJ, Sont JK, Strategies for Tailoring Asthma Treatment in Adults. JAMA-J AM MED ASSOC 2013;309 (2):135-136 [PubMed]
van der Schee MP, Fens N, Brinkman P, Bos LDJ, Angelo MD, Nijsen TME, Raabe R, Knobel HH, Vink TJ, Sterk PJ, Effect of transportation and storage using sorbent tubes of exhaled breath samples on diagnostic accuracy of electronic nose analysis. J BREATH RES 2013;7 (1):016002 [PubMed]
van der Sluijs KF, van de Pol MA, Kulik W, Dijkhuis A, Smids BS, van Eijk HW, Karlas JA, Molenkamp R, Wolthers KC, Johnston SL, van der Zee JS, Sterk PJ, Lutter R [Contributors: Berger M, Fens N, Yick D, Wagener AH , Amelink M, Reesink HJ, Bresser P, Kunst PWA , Venekamp LN, Majoor CJ , van Steenwijk RP, Jonkers RE]] , Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design. THORAX 2013;68 (12):1122-1130 [PubMed]
van Gaalen JL, Beerthuizen T, van der Meer V, van Reisen P, Redelijkheid GW, Snoeck-Stroband JB, Sont JK [Contributors: Assendelft WJJ, Bakker MJ, Bel EH, Detmar SB, de Jongste JC, Kaptein AA, van der Meer V, Rabe KF, Rikkers-Mutsaerts ERVM, Sont JK, van Stel HF, Sterk PJ, Thiadens HA, Toussaint PJ]] , Long-term outcomes of internet-based self-management support in adults with asthma: randomized controlled trial. J MED INTERNET RES 2013;15 (9):e188 [PubMed]
van Ooij PJAM. Pulmonary oxygen toxicity in professional diving: scire est mensurare?. s.l.: s.n.; 2013. 208p. ISBN 9789053357101 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sterk PJ; copromotor(s): van Hulst RA)
van Ooij PJAM, Hollmann MW, van Hulst RA, Sterk PJ, Assessment of pulmonary oxygen toxicity: relevance to professional diving; a review. RESP PHYSIOL NEUROBI 2013;189 (1):117-128 [PubMed]
Vijverberg SJH, Koenderman L, van Erp FC, van der Ent CK, Postma DS, Brinkman P, Sterk PJ, Raaijmakers JAM, Maitland-van der Zee AH, Inflammatory phenotypes underlying uncontrolled childhood asthma despite inhaled corticosteroid treatment: rationale and design of the PACMAN2 study. BMC PEDIATR 2013;13 (1):94 [PubMed]
Wagener AH , Yick CY, Brinkman P, van der Schee MP, Fens N, Sterk PJ, Toward composite molecular signatures in the phenotyping of asthma. ANN AM THORAC SOC 2013;10 (Suppl):S197-S205 [PubMed]
Wagener AH , Zwinderman AH, Luiten S, Fokkens WJ, Bel EH, Sterk PJ, van Drunen CM, The impact of allergic rhinitis and asthma on human nasal and bronchial epithelial gene expression. PLOS ONE 2013;8 (11):e80257 [PubMed]
Wheelock CE, Goss VM, Balgoma D, Nicholas B, Brandsma J, Skipp PJ, Snowden S, Burg D, D'Amico A, Horvath I, Chaiboonchoe A, Ahmed H, Ballereau S, Rossios C, Chung KF, Montuschi P, Fowler SJ, Adcock IM, Postle AD, Dahlén SE, Rowe A, Sterk PJ, Auffray C, Djukanovic R, Application of 'omics technologies to biomarker discovery in inflammatory lung diseases. EUR RESPIR J 2013;42 (3):802-825 [PubMed]
Yick CY. The airway smooth muscle in asthma: more than meets the eye. s.l.: s.n.; 2013. 211p. ISBN 9789461918161 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sterk PJ, Baas F; copromotor(s): Lutter R, Grünberg K)
Yick CY, Zwinderman AH, Kunst PW, Grünberg K, Mauad T, Dijkhuis A, Bel EH, Baas F, Lutter R, Sterk PJ, Transcriptome sequencing (RNA-Seq) of human endobronchial biopsies: asthma versus controls. EUR RESPIR J 2013;42 (3):662-670 [PubMed]
Yick CY, Zwinderman AH, Kunst PW, Grünberg K, Mauad T, Fluiter K, Bel EH, Lutter R, Baas F, Sterk PJ, Glucocorticoid-induced changes in gene expression of airway smooth muscle in patients with asthma. AM J RESP CRIT CARE 2013;187 (10):1076-1084 [PubMed]
Amelink M, de Nijs SB, Berger M, Weersink EJ , ten Brinke A, Sterk PJ, Bel EH, Non-atopic males with adult onset asthma are at risk of persistent airflow limitation. CLIN EXP ALLERGY 2012;42 (5):769-774 [PubMed]
Annoni R, Lanças T, Yukimatsu Tanigawa R, de Medeiros Matsushita M, de Morais Fernezlian S, Bruno A, Fernando Ferraz da Silva L, Roughley PJ, Battaglia S, Dolhnikoff M, Hiemstra PS, Sterk PJ, Rabe KF, Mauad T, Extracellular matrix composition in COPD. EUR RESPIR J 2012;40 (6):1362-1373 [PubMed]
Antó JM, Pinart M, Akdis M, Auffray C, Bachert C, Basagaña X, Carlsen KH, Guerra S, von Hertzen L, Illi S, Kauffmann F, Keil T, Kiley JP, Koppelman GH, Lupinek C, Martinez FD, Nawijn MC, Postma DS, Siroux V, Smit HA, Sterk PJ, Sunyer J, Valenta R, Valverde S, Akdis CA, Annesi-Maesano I, Ballester F, Benet M, Cambon-Thomsen A, Chatzi L, Coquet J, Demoly P, Gan W, Garcia-Aymerich J, Gimeno-Santos E, Guihenneuc-Jouyaux C, Haahtela T, Heinrich J, Herr M, Hohmann C, Jacquemin B, Just J, Kerkhof M, Kogevinas M, Kowalski ML, Lambrecht BN, Lau S, Lødrup Carlsen KC, Maier D, Momas I, Noel P, Oddie S, Palkonen S, Pin I, Porta D, Punturieri A, Rancière F, Smith RA, Stanic B, Stein RT, van de Veen W, van Oosterhout AJM, Varraso R, Wickman M, Wijmenga C, Wright J, Yaman G, Zuberbier T, Bousquet J, Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: A Mechanisms of the Development of Allergy (MeDALL) Seminar. J ALLERGY CLIN IMMUN 2012;129 (4):943-U421 [PubMed]
Bos LDJ, Sterk PJ, Schultz MJ, Measuring Metabolomics in Acute Lung Injury: Choosing the Correct Compartment?. AM J RESP CRIT CARE 2012;185 (7):789 [PubMed]
Bos LDJ, Sterk PJ, Schultz MJ, Metabolomics in critically ill patients: focus on breath. ANNUAL UPDATE IN INTENSIVE CARE AND EMERGENCY MEDICINE 2012;2012:53-62
Bousquet J, Anto JM, Demoly P, Schünemann HJ, Togias A, Akdis M, Auffray C, Bachert C, Bieber T, Bousquet PJ, Carlsen KH, Casale TB, Cruz AA, Keil T, Lodrup Carlsen KC, Maurer M, Ohta K, Papadopoulos NG, Roman Rodriguez M, Samolinski B, Agache I, Andrianarisoa A, Ang CS, Annesi-Maesano I, Ballester F, Baena-Cagnani CE, Basagaña X, Bateman ED, Bel EH, Bedbrook A, Beghé B, Beji M, Ben Kheder A, Benet M, Bennoor KS, Bergmann KC, Berrissoul F, Bindslev Jensen C, Bleecker ER, Bonini S, Boner AL, Boulet LP, Brightling CE, Brozek JL, Bush A, Busse WW, Camargos PAM, Canonica GW, Carr W, Cesario A, Chen YZ, Chiriac AM, Costa DJ, Cox L, Custovic A, Dahl R, Darsow U, Didi T, Dolen WK, Douagui H, Dubakiene R, El-Meziane A, Fonseca JA, Fokkens WJ, Fthenou E, Gamkrelidze A, Garcia-Aymerich J, Gerth van Wijk R, Gimeno-Santos E, Guerra S, Haahtela T, Haddad H, Hellings PW, Hellquist-Dahl B, Hohmann C, Howarth P, Hourihane JO, Humbert M, Jacquemin B, Just J, Kalayci O, Kaliner MA, Kauffmann F, Kerkhof M, Khayat G, Koffi N'goran B, Kogevinas M, Koppelman GH, Kowalski ML, Kull I, Kuna P, Larenas D, Lavi I, Le LT, Lieberman P, Lipworth B, Mahboub B, Makela MJ, Martin F, Martinez FD, Marshall GD, Mazon A, Melen E, Meltzer EO, Mihaltan F, Mohammad Y, Mohammadi A, Momas I, Morais-Almeida M, Mullol J, Muraro A, Naclerio R, Nafti S, Namazova-Baranova L, Nawijn MC, Nyembue TD, Oddie S, O'Hehir RE, Okamoto Y, Orru MP, Ozdemir C, Ouedraogo GS, Palkonen S, Panzner P, Passalacqua G, Pawankar R, Pigearias B, Pin I, Pinart M, Pison C, Popov TA, Porta D, Postma DS, Price D, Rabe KF, Ratomaharo J, Reitamo S, Rezagui D, Ring J, Roberts R, Roca J, Rogala B, Romano A, Rosado-Pinto J, Ryan D, Sanchez-Borges M, Scadding GK, Sheikh A, Simons FER, Siroux V, Schmid-Grendelmeier PD, Smit HA, Sooronbaev T, Stein RT, Sterk PJ, Sunyer J, Terreehorst I, Toskala E, Tremblay Y, Valenta R, Valeyre D, Vandenplas O, van Weel C, Vassilaki M, Varraso R, Viegi G, Wang DY, Wickman M, Williams D, Wöhrl S, Wright J, Yorgancioglu A, Yusuf OM, Zar HJ, Zernotti ME, Zidarn M, Zhong N, Zuberbier T [Contributors: Bousquet J, Anto JM, Demoly P, Schünemann HJ, Togias A, Akdis M, Auffray C, Bachert C, Bieber T, Bousquet PJ, Carlsen KH, Casale TB, Cruz AA, Keil T, Lodrup Carlsen KC, Maurer M, Ohta K, Papadopoulos NG, Roman Rodriguez M, Samolinski B, Agache I, Andrianarisoa A, Ang CS, Annesi-Maesano I, Ballester F, Baena-Cagnani CE, Basagaña X, Bateman ED, Bel EH, Bedbrook A, Beghé B, Beji M, Ben Kheder A, Benet M, Bennoor KS, Bergmann KC, Berrissoul F, Bindslev Jensen C, Bleecker ER, Bonini S, Boner AL, Boulet LP, Brightling CE, Brozek JL, Bush A, Busse WW, Camargos PAM, Canonica GW, Carr W, Cesario A, Chen YZ, Chiriac AM, Costa DJ, Cox L, Custovic A, Dahl R, Darsow U, Didi T, Dolen WK, Douagui H, Dubakiene R, El-Meziane A, Fonseca JA, Fokkens WJ, Fthenou E, Gamkrelidze A, Garcia-Aymerich J, Gerth van Wijk R, Gimeno-Santos E, Guerra S, Haahtela T, Haddad H, Hellings PW, Hellquist-Dahl B, Hohmann C, Howarth P, Hourihane JO, Humbert M, Jacquemin B, Just J, Kalayci O, Kaliner MA, Kauffmann F, Kerkhof M, Khayat G, Koffi N'goran B, Kogevinas M, Koppelman GH, Kowalski ML, Kull I, Kuna P, Larenas D, Lavi I, Le LT, Lieberman P, Lipworth B, Mahboub B, Makela MJ, Martin F, Martinez FD, Marshall GD, Mazon A, Melen E, Meltzer EO, Mihaltan F, Mohammad Y, Mohammadi A, Momas I, Morais-Almeida M, Mullol J, Muraro A, Naclerio R, Nafti S, Namazova-Baranova L, Nawijn MC, Nyembue TD, Oddie S, O'Hehir RE, Okamoto Y, Orru MP, Ozdemir C, Ouedraogo GS, Palkonen S, Panzner P, Passalacqua G, Pawankar R, Pigearias B, Pin I, Pinart M, Pison C, Popov TA, Porta D, Postma DS, Price D, Rabe KF, Ratomaharo J, Reitamo S, Rezagui D, Ring J, Roberts R, Roca J, Rogala B, Romano A, Rosado-Pinto J, Ryan D, Sanchez-Borges M, Scadding GK, Sheikh A, Simons FER, Siroux V, Schmid-Grendelmeier PD, Smit HA, Sooronbaev T, Stein RT, Sterk PJ, Sunyer J, Terreehorst I, Toskala E, Tremblay Y, Valenta R, Valeyre D, Vandenplas O, van Weel C, Vassilaki M, Varraso R, Viegi G, Wang DY, Wickman M, Williams D, Wöhrl S, Wright J, Yorgancioglu A, Yusuf OM, Zar HJ, Zernotti ME, Zidarn M, Zhong N, Zuberbier T]] , Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper. INT ARCH ALLERGY IMM 2012;158 (3):216-231 [PubMed]
Budulac SE, Boezen HM, Hiemstra PS, Lapperre TS, Vonk JM, Timens W, Postma DS [Contributors: Kauffman HF, de Reus D, Boezen HM, Jansen DF, Vonk JM, Barentsen MDW, Timens W, Zeinstra-Smit M, Luteijn AJ, van der Molen T, ter Veen G, Gosman MME, ten Hacken NHT, Kerstjens HAM, van Maaren MS, Postma DS, Veltman CA, Verbokkem A, Verhage I, Vink-Klooster HK, Snoeck-Stroband JB, Thiadens H, Sont JK, Bajema I, Gast-Strookman J, Hiemstra PS, Janssen K, Lapperre TS, Rabe KF, van Schadewijk A, Smit-Bakker J, Stolk J, Tire' ACJA, van der Veen H, Wijffels MME, Willems LNA, Sterk PJ, Mauad T]] , Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease. PLOS ONE 2012;7 (8):e43124 [PubMed]
Budulac SE, Postma DS, Hiemstra PS, Lapperre TS, Kunz LIZ, Vonk JM, Marike Boezen H, Timens W [Contributors: Kauffman HF, de Reus D, Boezen HM, Jansen DF, Vonk JM, Barentsen MDW, Timens W, Zeinstra-Smit M, Luteijn AJ, van der Molen T, ter Veen G, Gosman MME, ten Hacken NHT, Kerstjens HAM, van Maaren MS, Postma DS, Veltman CA, Verbokkem A, Verhage I, Klooster HK, Snoeck-Stroband JB, Thiadens H, Sont JK, Bajema I, Gast-Strookman J, Hiemstra PS, Janssen K, Lapperre TS, Rabe KF, van Schadewijk A, Smit-Bakker J, Stolk J, Tiré ACJA, van der Veen H, Wijffelsand MME, Willems LNA, Sterk PJ, Mauad T]] , Multidrug resistance-associated protein 1 and lung function decline with or without long-term corticosteroids treatment in COPD. EUR J PHARMACOL 2012;696 (1-3):136-142 [PubMed]
D'Amico A, Di Natale C, Falconi C, Martinelli E, Paolesse R, Pennazza G, Santonico M, Sterk PJ, Detection and identification of cancers by the electronic nose. EXPERT OPIN MED DIAGN 2012;6 (3):175-185 [PubMed]
Dragonieri S. An electronic nose in respiratory disease. Amsterdam: s.n.; 2012. 145p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sterk PJ; copromotor(s): )
Dragonieri S, van der Schee MP, Massaro T, Schiavulli N, Brinkman P, Pinca A, Carratú P, Spanevello A, Resta O, Musti M, Sterk PJ, An electronic nose distinguishes exhaled breath of patients with Malignant Pleural Mesothelioma from controls. LUNG CANCER 2012;75 (3):326-331 [PubMed]
Ferreira DS, Annoni R, Silva LFF, Buttignol M, Santos ABG, Medeiros MCR, Andrade LNS, Yick CY, Sterk PJ, Sampaio JLM, Dolhnikoff M, Wenzel SE, Mauad T, Toll-like receptors 2, 3 and 4 and thymic stromal lymphopoietin expression in fatal asthma. CLIN EXP ALLERGY 2012;42 (10):1459-1471 [PubMed]
Hashimoto S, Sterk PJ, Bel EH, Pragmatic trials: how to adjust for the 'Hawthorne effect'? response. THORAX 2012;67 (6):562
Hubers AJ, Heideman DAM, Herder GJM, Burgers SA, Sterk PJ, Kunst PW, Smit HJ, Postmus PE, Witte BI, Duin S, Snijders PJF, Smit EF, Thunnissen E, Prolonged sampling of spontaneous sputum improves sensitivity of hypermethylation analysis for lung cancer. J CLIN PATHOL 2012;65 (6):541-545 [PubMed]
Postma DS, Sterk PJ, Chronic obstructive pulmonary disease phenotypes: current rather than future perspectives. AM J RESP CRIT CARE 2012;185 (5):589-90; author reply 590 [PubMed]
Ricciardolo FLM, Di Stefano A, Silvestri M, van Schadewijk AM, Malerba M, Hiemstra PS, Sterk PJ, EXHALED NITRIC OXIDE IS RELATED TO BRONCHIAL EOSINOPHILIA AND AIRWAY HYPERRESPONSIVENESS TO BRADYKININ IN ALLERGEN-INDUCED ASTHMA EXACERBATION. INT J IMMUNOPATH PH 2012;25 (1):175-182 [PubMed]
Rikkers-Mutsaerts ERVM, Winters AE, Bakker MJ, van Stel HF, van der Meer V, de Jongste JC, Sont JK [Contributors: Bakker MJ, van den Hout WB, Kievit J, van der Meer V, Sont JK, Kaptein AA, Rikkers-Mutsaerts ERVM, Rabe KF, Bel EH, Sterk PJ, Detmar SB, Otten W, van Stel HF, Roldaan AC, de Jongste JC, Toussaint PJ, van der Berg NJ, Gosen JJ, Hekkelaan MW, de Graaf Gasthuis R, Kouwenberg JM, Children J, Langendonck L, Mérelle M, van Zoest JGCM]] , Internet-based self-management compared with usual care in adolescents with asthma: a randomized controlled trial. PEDIATR PULM 2012;47 (12):1170-1179 [PubMed]
Santonico M, Pennazza G, Capuano R, Falconi C, Vink TJ, Knobel HH, van der Schee MP, Sterk PJ, Montuschi P, D'Amico A, Electronic noses calibration procedure in the context of a multicentre medical study. SENSOR ACTUAT B-CHEM 2012;173:555-561
Snoeck-Stroband JB. Effects of inhaled corticosteroids in the GLUCOLD study. Leiden: s.n.; 2012. 216p. Proefschrift Universiteit Leiden, Afdeling Medische Besliskunde, Longziekten en Public Health en Eerstelijnsgeneeskunde. (Promotor(s): Sterk PJ, Postma DS, Hiemstra PS; copromotor(s): )
ter Riet G, Korevaar DA, Leenaars M, Sterk PJ, van Noorden CJF, Bouter LM, Lutter R, Elferink RPO, Hooft L, Publication Bias in Laboratory Animal Research: A Survey on Magnitude, Drivers, Consequences and Potential Solutions. PLOS ONE 2012;7 (9):e43404 [PubMed]
van den Berge M, Vonk JM, Gosman M, Lapperre TS, Snoeck-Stroband JB, Sterk PJ, Kunz LIZ, Hiemstra PS, Timens W, ten Hacken NHT, Kerstjens HAM, Postma DS, Clinical and inflammatory determinants of bronchial hyperresponsiveness in COPD. EUR RESPIR J 2012;40 (5):1098-1105 [PubMed]
van Ooij PJAM, van Hulst RA, Houtkooper A, van der Weide TJS, Sterk PJ, Lung function before and after oxygen diving: a randomized crossover study. UNDERSEA HYPERBAR M 2012;39 (3):699-707 [PubMed]
Yick CY, Ferreira DS, Annoni R, von der Thüsen JH, Kunst PW, Bel EH, Lutter R, Mauad T, Sterk PJ, Extracellular matrix in airway smooth muscle is associated with dynamics of airway function in asthma. ALLERGY 2012;67 (4):552-559 [PubMed]
Bel EH, Sousa A, Fleming L, Bush A, Chung KF, Versnel J, Wagener AH , Wagers SS, Sterk PJ, Compton CH [Contributors: Bel EH, Bergeron C, Bisgaard H, Bleecker E, Boulet LP, Bousquet J, Brightling CE, Bush A, Castro M, Chanez P, Chung KF, Compton CH, Cookson W, de Boer WI, Djukanovic R, Fleming L, Gaga M, Hedlin G, Howarth PH, Ivanoff N, Kiley J, Larsson LG, Menzies-Gow A, Meyers DA, Myles D, Nething K, O'Byrne PM, Palkonen S, Polosa R, Purkins L, Rohou S, Serdrevic D, Sousa A, Sterk PJ, Ventresca G, Versnel J, Wagener AK, Wagers SS, Wenzel SE]] , Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI). THORAX 2011;66 (10):910-917 [PubMed]
Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C, Systems medicine and integrated care to combat chronic noncommunicable diseases. GENOME MED 2011;3 (7):43 [PubMed]
de Nijs SB, Fens N, Lutter R, Dijkers E, Krouwels FH, Smids-Dierdorp BS, van Steenwijk RP, Sterk PJ, Airway inflammation and mannitol challenge test in COPD. RESP RES 2011;12 (1):11 [PubMed]
Fens N. Breathomics in pulmonary disease. s.l.: s.n.; 2011. 175p. ISBN 9789090263397 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sterk PJ; copromotor(s): )
Fens N, de Nijs SB, Peters S, Dekker T, Knobel HH, Vink TJ, Willard NP, Zwinderman AH, Krouwels FH, Janssen HG, Lutter R, Sterk PJ, Exhaled air molecular profiling in relation to inflammatory subtype and activity in COPD. EUR RESPIR J 2011;38 (6):1301-1309 [PubMed]
Fens N, Roldaan AC, van der Schee MP, Boksem RJ, Zwinderman AH, Bel EH, Sterk PJ, External validation of exhaled breath profiling using an electronic nose in the discrimination of asthma with fixed airways obstruction and chronic obstructive pulmonary disease. CLIN EXP ALLERGY 2011;41 (10):1371-1378 [PubMed]
Hashimoto S, ten Brinke A, Roldaan AC, van Veen IH, Möller GM, Sont JK, Weersink EJM , van der Zee JS, Braunstahl GJ, Zwinderman AH, Sterk PJ, Bel EH, Internet-based tapering of oral corticosteroids in severe asthma: a pragmatic randomised controlled trial. THORAX 2011;66 (6):514-520 [PubMed]
Honkoop PJ, Loymans RJB, Termeer EH, Snoeck-Stroband JB, Bakker MJ, Assendelft WJJ, Sterk PJ, ter Riet G, Schermer TRJ, Sont JK, Asthma control cost-utility randomized trial evaluation (ACCURATE): the goals of asthma treatment. BMC PULM MED 2011;11 (1):53 [PubMed]
Kaminsky DA, Irvin CG, Sterk PJ, Complex systems in pulmonary medicine: a systems biology approach to lung disease. J APPL PHYSIOL 2011;110 (6):1716-1722 [PubMed]
Kunz LIZ, Lapperre TS, Snoeck-Stroband JB, Budulac SE, Timens W, van Wijngaarden S, Schrumpf JA, Rabe KF, Postma DS, Sterk PJ, Hiemstra PS [Contributors: Kauffman HF, de Reus D, Boezen HM, Jansen DF, Vonk JM, Barentsen MDW, Timens W, Zeinstra-Smit M, Luteijn AJ, van der Molen T, ter Veen G, Gosman MME, ten Hacken NHT, Kerstjens HAM, van Maaren MS, Postma DS, Veltman CA, Verbokkem A, Verhage I, Vink-Klooster HK, Thiadens HA, Snoeck-Stroband JB, Sont JK, Gast-Strookman J, Hiemstra PS, Janssen K, Lapperre TS, Rabe KF, van Schadewijk A, Schrumpf JA, Smit-Bakker J, Sterk PJ, Stolk J, Tiré ACJA, van der Veen H, Wijffels MME, Willems LNA, Mauad T]] , Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD. RESP RES 2011;12 (1):34 [PubMed]
Loymans RJB, ter Riet G, Sterk PJ, Definitions of asthma exacerbations. CURR OPIN ALLERGY CL 2011;11 (3):181-186 [PubMed]
Loymans R, ter Riet G, Sterk PJ, Assessing primary care physicians' beliefs and attitudes of asthma exacerbation treatment and follow-up. OPEN RESPIR MED J 2011;5:10 [PubMed]
O'Byrne PM, Nair P, Sterk PJ, In memoriam: Frederick E Hargreave (1938-2011). THORAX 2011;66 (12):1101-1102 [PubMed]
Slats AM. Towards restoring the physiological protection against airway narrowing in asthma; Take a deep breath!. S.l.: s.n.; 2011. 205p. ISBN 978-94-6169-159-0 Proefschrift Leids Universitair Medisch Centrum, Afdeling Longziekten. (Promotor(s): Sterk PJ, Rabe KF; copromotor(s): )
Steiling K, Berge Mvd, Sebastiani P, O'Connor G, Zhang X, Liu G, Xiao J, Alekseyev Y, Campbell J, Coxson HO, Hogg JC, McWilliams A, Timens W, Hiemstra PS, Sterk PJ, Sin D, Postma D, Lam S, Lenburg ME, Spira A, Airway Gene Expression as a Molecular Phenotype of COPD. PROC AM THORAC SOC 2011;8 (2):208 [PubMed]
Sterk PJ, "COPD-Lite": do you like the taste?. AM J RESP CRIT CARE 2011;184 (4):486; author reply 486-486; author reply 487 [PubMed]
Sterk PJ, Bel EH, Small airways, big challenge. EUR RESPIR REV 2011;20 (119):1-2 [PubMed]
Turchiarelli V, Schinkel J, Molenkamp R, Foschino Barbaro MP, Carpagnano GE, Spanevello A, Lutter R, Bel EH, Sterk PJ, Repeated virus identification in the airways of patients with mild and severe asthma during prospective follow-up. ALLERGY 2011;66 (8):1099-1106 [PubMed]
van Beek SC, Nhung NV, Sy DN, Sterk PJ, Tiemersma EW, Cobelens FGJ, Measurement of exhaled nitric oxide as a potential screening tool for pulmonary tuberculosis. INT J TUBERC LUNG D 2011;15 (2):185-191 [PubMed]
van der Meer V, van den Hout WB, Bakker MJ, Rabe KF, Sterk PJ, Assendelft WJJ, Kievit J, Sont JK [Contributors: Assendelft WJJ, Thiadens HA, Bakker MJ, van den Hout WB, Kievit J, van der Meer V, Sont JK, Kaptein AA, Rikkers-Mutsaerts ERVM, Rabe KF, Bel EH, Sterk PJ, Detmar SB, Otten W, van Stel HF, Roldaan AC, de Jongste JC, Toussaint PJ]] , Cost-effectiveness of Internet-based self-management compared with usual care in asthma. PLOS ONE 2011;6 (11):e27108 [PubMed]
van Ooij PJAM, van Hulst RA, Houtkooper A, Sterk PJ, Differences in spirometry and diffusing capacity after a 3-h wet or dry oxygen dive with a PO(2) of 150 kPa. CLIN PHYSIOL FUNCT I 2011;31 (5):405-410 [PubMed]
Yick CY, von der Thüsen JH, Bel EH, Sterk PJ, Kunst PW, In vivo imaging of the airway wall in asthma: fibered confocal fluorescence microscopy in relation to histology and lung function. RESP RES 2011;12 (1):85 [PubMed]
Auffray C, Adcock IM, Chung KF, Djukanovic R, Pison C, Sterk PJ, An Integrative Systems Biology Approach to Understanding Pulmonary Diseases. CHEST 2010;137 (6):1410-1416 [PubMed]
Budulac SE, Postma DS, Hiemstra PS, Kunz LIZ, Siedlinski M, Smit HA, Vonk JM, Rutgers B, Timens W, Boezen HM [Contributors: Kauffman HF, de Reus D, Boezen HM, Jansen DF, Vonk JM, Barentsen MDW, Timens W, Zeinstra-Smit M, Luteijn AJ, van der Molen T, ter Veen G, Gosman MME, ten Hacken NHT, Kerstjens HAM, van Maaren MS, Postma DS, Veltman CA, Verbokkem A, Verhage I, Vink-Kloosters HK, Snoeck-Stroband JB, Thiadens H, Sont JK, Bajema I, Gast-Strookman J, Hiemstra PS, Janssen K, Lapperre TS, Rabe KF, van Schadewijk A, Smit-Bakker J, Stolk J, Tire' ACJA, van der Veen H, Wijffels MME, Willems LNA, Sterk PJ, Mauad T]] , Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD. RESP RES 2010;11:60 [PubMed]
Deatrick K, Baker N, Deroo S, Elfline MA, Sood V, Stabler S, Blackburn SA, Luke CE, Wakefield TW, Henke PK, Pannucci CJ, Bailey S, Fisher C, Clavijo-Alvarez J, Hamill J, Hume K, Wakefield T, Rubin J, Wilkins E, Hoxworth R, Sfyroeras GS, Rubio V, Ravi RD, Pittaluga P, Chastanet S, Locret T, Rousset O, Kordowicz A, Ferguson G, Salaman R, Onwudike M, Gauw SA, Fens N, Knobel HH, de Bokx PK, Pronk P, van Vlijmen-van Keulen CJ, Gaastra MTW, Mooij MC, Sterk PJ, Sapelkin SV, Dan VN, Vetyugova LV, Broholm R, Jensen LP, Sillesen H, Kreiner S, Bækgaard N, Qureshi MI, McDonald A, Wing L, Lim CS, Gohel M, Ellis M, Franklin IJ, Davies AH, Pierce I, Kalodiki E, Lattimer C, Geroulakos G, Gatehouse PD, Firmin DN, Gemayel G, Christenson JT, van den Bos RR, Milleret R, Neumann M, Nijsten T, Wiszniewski A, Szopinski P, Bilski R, Proniewski J, Ratajczak J, Romera-Villegas A, Cairols MA, Martí-Mestre X, Riera-Batalla S, Martinez-Rico C, Ahmad A, Saha P, Rolph R, Patel AS, Modarai B, Sabharwal T, Waltham M, Lauwers K, Hertoghs M, van Schil P, de Maeseneer M, Rosales A, Sandbæk G, Jørgensen JJ, Uhl JF, Gillot C, Lawson JA, Vuylsteke M, Th DB, Dompe G, di Crisci D, Miquel Abbab C, Mordon S, Shepherd AC, Gohel MS, Brown LC, Ragg JC, Martel L, Wolschner J, Nagy J, Shadid N, Nelemans P, Sommer A, Lawaetz M, Rasmussen LH, Bjoern L, Blemings A, Eklöf B, Neffendorf JE, Soobrah R, Grewal P, Gibson K, Wright D, Rush J, Suplick G, Evans E, Nelzén O, Reeder SWI, de Roos KP, Neumann HAM, King T, Walshe TM, Browne AM, O'Riordan C, O'Sullivan GJ, Eleventh meeting of the European venous forum: antwerp, belgium, 24-26 june 2010. PHLEBOLOGY 2010;25 (6):296-311 [PubMed]
den Otter I, Silva LFF, Carvalho ALN, Pires-Neto RC, Annoni R, Ferreira DS, Bajema I, van Schadewijk A, Rabe KF, Dolhnikoff M, Sterk PJ, Hiemstra PS, Mauad T, High-affinity immunoglobulin E receptor expression is increased in large and small airways in fatal asthma. CLIN EXP ALLERGY 2010;40 (10):1473-1481 [PubMed]
Diamant Z, Boot JD, Mantzouranis E, Flohr R, Sterk PJ, Gerth van Wijk R, Biomarkers in asthma and allergic rhinitis. PULM PHARMACOL THER 2010;23 (6):468-481 [PubMed]
Engbers M, Vachier I, Sterk PJ, Bourdin A, Gras D, Godard P, Chanez P, Mild asthma in overweight women: A new phenotype?. RESP MED 2010;104 (8):1138-1144 [PubMed]
Fens N, Douma RA, Sterk PJ, Kamphuisen PW, Breathomics as a diagnostic tool for pulmonary embolism. J THROMB HAEMOST 2010;8 (12):2831-2833 [PubMed]
Lapperre TS. Airway pathology in COPD: smoking cessation and pharmacological treatment intervention. Results from the GLUCOLD study.. Leiden: s.n.; 2010. 167p. ISBN 978-90-9025063-2 Proefschrift Universiteit Leiden, Afdeling Longziekten. (Promotor(s): Hiemstra PS, Sterk PJ, Timens W; copromotor(s): )
Lazar Z, Fens N, Van der Maten J, van der Schee MP, Wagener AH , de Nijs SB, Dijkers E, Sterk PJ, Electronic nose breathprints are independent of acute changes in airway caliber in asthma. SENSORS-BASEL 2010;10 (10):9127-9138 [PubMed]
Muskulus M, Slats AM, Sterk PJ, Verduyn-Lunel S, Fluctuations and determinism of respiratory impedance in asthma and chronic obstructive pulmonary disease. J APPL PHYSIOL 2010;109 (6):1582-1591 [PubMed]
Snoeck-Stroband JB, Lapperre TS, Gosman MME, Boezen HM, ten Hacken NHT, Sont JK, Hiemstra PS, Timens W, Sterk PJ, Postma DS, Langdurige behandeling met inhalatiesteroïden heeft gunstig effect bij matig ernstige COPD*. NED TIJDSCHR GENEESKD 2010;154 (42):A2365 [PubMed]
van der Meer V, van Stel HF, Bakker MJ, Roldaan AC, Assendelft WJJ, Sterk PJ, Rabe KF, Sont JK [Contributors: Assendelft WJJ, Bakker MJ, Bel EH, Detmar SB, de Jongste JC, Kaptein AA, van der Meer V, Otten W, Rabe KF, Rikkers-Mutsaerts ERVM, Roldaan AC, Sont JK, van Stel HF, Sterk PJ, Thiadens HA, Toussaint PJ]] , Weekly self-monitoring and treatment adjustment benefit patients with partly controlled and uncontrolled asthma: an analysis of the SMASHING study. RESP RES 2010;11 (1):74 [PubMed]
Beasley R, Martinez FD, Hackshaw A, Rabe KF, Sterk PJ, Djukanovic R, Safety of long-acting beta-agonists: urgent need to clear the air remains. EUR RESPIR J 2009;33 (1):3-5 [PubMed]
Boot JD. Non-invasive sampling methods of inflammatory biomarkers in asthma and allergic rhinitis. Leiden: s.n.; 2009. 192p. Proefschrift Universiteit Leiden, Centre for Human Drug Research. (Promotor(s): Cohen AF, Sterk PJ; copromotor(s): Diamant Z)
Dragonieri S, Annema JT, Schot R, van der Schee MPC, Spanevello A, Carratú P, Resta O, Rabe KF, Sterk PJ, An electronic nose in the discrimination of patients with non-small cell lung cancer and COPD. LUNG CANCER 2009;64 (2):166-170 [PubMed]
Fens N, Zwinderman AH, van der Schee MP, de Nijs SB, Dijkers E, Roldaan AC, Cheung D, Bel EH, Sterk PJ, Exhaled Breath Profiling Enables Discrimination of Chronic Obstructive Pulmonary Disease and Asthma. AM J RESP CRIT CARE 2009;180 (11):1076-1082 [PubMed]
Koczulla R, Dragonieri S, Schot R, Bals R, Gauw SA, Vogelmeier C, Rabe KF, Sterk PJ, Hiemstra PS, Comparison of exhaled breath condensate pH using two commercially available devices in healthy controls, asthma and COPD patients. RESP RES 2009;10 (1):78 [PubMed]
Lapperre TS, Snoeck-Stroband JB, Gosman MME, Jansen DF, van Schadewijk A, Thiadens HA, Vonk JM, Boezen HM, ten Hacken NHT, Sont JK, Rabe KF, Kerstjens HAM, Hiemstra PS, Timens W, Postma DS, Sterk PJ [Contributors: Kauffman HF, de Reus D, Boezen HM, Jansen DF, Vonk JM, Barentsen MDW, Timens W, Zeinstra-Smit M, Luteijn AJ, van der Molen T, ter Veen G, Gosman MME, ten Hacken NHT, Kerstjens HAM, van Maaren MS, Postma DS, Veltman CA, Verbokkem A, Verhage I, Vink-Klooster HK, Thiadens HA, Snoeck-Stroband JB, Sont JK, Gast-Strookman J, Hiemstra PS, Janssen K, Lapperre TS, Rabe KF, van Schadewijk A, Schrumpf JA, Smit-Bakker J, Sterk PJ, Stolk J, Tiré ACJA, van der Veen H, Wijffels MME, Willems LNA, Mauad T]] , Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial. ANN INTERN MED 2009;151 (8):517-527 [PubMed]
Nuijsink M, Hop WCJ, Sterk PJ, Duiverman EJ, de Jongste JC, Behandeling van astma bij kinderen op geleide van bronchiale hyperreactiviteit. NED TIJDSCHR GENEESKD 2009;153 (22):1059-1066 [PubMed]
Reddel HK, Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HAM, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Sullivan SD, Szefler SJ, Thomas MD, Wenzel SE [Contributors: Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HAM, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Reddel HK, Sears MR, Sterk PJ, Stoloff SW, Szefler SJ, Sullivan SD, Taylor DR, Thomas MD, Wenzel SE, Sullivan EJ, Chowdhury BA, Lyons DJ]] , An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. AM J RESP CRIT CARE 2009;180 (1):59-99 [PubMed]
van der Meer V, Bakker MJ, van den Hout WB, Rabe KF, Sterk PJ, Kievit J, Assendelft WJJ, Sont JK [Contributors: Assendelft WJJ, Thiadens HA, Bakker MJ, van den Hout WB, Kievit J, van der Meer V, Sont JK, Kaptein AA, Rikkers-Mutsaerts ERVM, Rabe KF, Bel EHD, Sterk PJ, Detmar SB, Otten W, van Stel HF, Roldaan AC, de Jongste JC, Toussaint PJ]] , Internet-based self-management plus education compared with usual care in asthma: a randomized trial. ANN INTERN MED 2009;151 (2):110-120 [PubMed]
van Rensen ELJ, Evertse CE, van Schadewijk WAAM, van Wijngaarden S, Ayre G, Mauad T, Hiemstra PS, Sterk PJ, Rabe KF, Eosinophils in bronchial mucosa of asthmatics after allergen challenge: effect of anti-IgE treatment. ALLERGY 2009;64 (1):72-80 [PubMed]
van Veen IH, ten Brinke A, Gauw SA, Sterk PJ, Rabe KF, Bel EH, Consistency of sputum eosinophilia in difficult-to-treat asthma: A 5-year follow-up study. J ALLERGY CLIN IMMUN 2009;124 (3):615-617 [PubMed]
Rabe KF, Sterk PJ, Five good reasons to read (and cite) the ERJ. EUR RESPIR J 2008;31 (1):1-2
Rabe KF, Sterk PJ, Your 10,000 manuscripts. EUR RESPIR J 2008;32 (6):1425 [PubMed]
Singh A, Sterk PJ, Noninvasive ventilation and the potential risk of transmission of infection. EUR RESPIR J 2008;32 (3):816 [PubMed]
Slats AM, Janssen K, de Jeu RC, van der Plas DT, Schot R, van den Aardweg JG, Sterk PJ, Enhanced airway dilation by positive-pressure inflation of the lungs compared with active deep inspiration in patients with asthma. J APPL PHYSIOL 2008;105 (6):1725-1732 [PubMed]
Slats AM, Janssen K, van Schadewijk A, van der Plas DT, Schot R, van den Aardweg JG, de Jongste JC, Hiemstra PS, Mauad T, Rabe KF, Sterk PJ, Expression of smooth muscle and extracellular matrix proteins in relation to airway function in asthma. J ALLERGY CLIN IMMUN 2008;121 (5):1196-1202 [PubMed]
Snoeck-Stroband JB, Lapperre TS, Gosman MME, Boezen HM, Timens W, ten Hacken NHT, Sont JK, Sterk PJ, Hiemstra PS, Chronic bronchitis sub-phenotype within COPD: inflammation in sputum and biopsies. EUR RESPIR J 2008;31 (1):70-77 [PubMed]
Sterk PJ, Yick CY, Slats AM, The secret life of steroids in asthma. EUR RESPIR J 2008;32 (5):1135-1137 [PubMed]
Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HAM, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Szefler SJ, Sullivan SD, Thomas MD, Wenzel SE, Reddel HK, A new perspective on concepts of asthma severity and control. EUR RESPIR J 2008;32 (3):545-554 [PubMed]
van Veen IH, ten Brinke A, Sterk PJ, Rabe KF, Bel EH, Airway inflammation in obese and nonobese patients with difficult-to-treat asthma. ALLERGY 2008;63 (5):570-574 [PubMed]
van Veen IH, ten Brinke A, Sterk PJ, Sont JK, Gauw SA, Rabe KF, Bel EH, Exhaled nitric oxide predicts lung function decline in difficult-to-treat asthma. EUR RESPIR J 2008;32 (2):344-349 [PubMed]
An SS, Bai TR, Bates JHT, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Pare PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PSP, Smith PG, Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L, Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. EUR RESPIR J 2007;29 (5):834-860 [PubMed]
Battaglia S, Mauad T, van Schadewijk AM, Vignola AM, Rabe KF, Bellia V, Sterk PJ, Hiemstra PS, Differential distribution of inflammatory cells in large and small airways in smokers. J CLIN PATHOL 2007;60 (8):907-911 [PubMed]
Boot JD, de Haas S, Tarasevych S, Roy C, Wang L, Amin D, Cohen J, Sterk PJ, Miller B, Paccaly A, Burggraaf J, Cohen AF, Diamant Z, Effect of an NK1/NK2 receptor antagonist on airway responses and inflammation to allergen in asthma. AM J RESP CRIT CARE 2007;175 (5):450-457 [PubMed]
Boulet LP, Sterk PJ, Airway remodelling: the future. EUR RESPIR J 2007;30 (5):831-834 [PubMed]
Boulet LP, Sterk PJ, A new series on airway remodelling. EUR RESPIR J 2007;29 (2):231-232 [PubMed]
Chanez P, Wenzel SE, Anderson GP, Anto JM, Bel EH, Boulet LP, Brightling CE, Busse WW, Castro M, Dahlen B, Dahlen SE, Fabbri LM, Holgate ST, Humbert M, Gaga M, Joos GF, Levy B, Rabe KF, Sterk PJ, Wilson SJ, Vachier I, Severe asthma in adults: what are the important questions?. J ALLERGY CLIN IMMUN 2007;119 (6):1337-1348 [PubMed]
Decramer M, Berglund E, Costabel U, Sterk PJ, Rabe KF, In memoriam professor Paul Vermeire, 1936-2007: a tribute from the ERJ chief editors. EUR RESPIR J 2007;30 (5):819-820
Dragonieri S, Schot R, Mertens BJA, le Cessie S, Gauw SA, Spanevello A, Resta O, Willard NP, Vink TJ, Rabe KF, Bel EH, Sterk PJ, An electronic nose in the discrimination of patients with asthma and controls. J ALLERGY CLIN IMMUN 2007;120 (4):856-862 [PubMed]
Grootendorst DC, Gauw SA, Verhoosel RM, Sterk PJ, Hospers JJ, Bredenbröker D, Bethke TD, Hiemstra PS, Rabe KF, Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD. THORAX 2007;62 (12):1081-1087 [PubMed]
Hylkema MN, Sterk PJ, de Boer WI, Postma DS, Tobacco use in relation to COPD and asthma. EUR RESPIR J 2007;29 (3):438-445 [PubMed]
Lapperre TS, Sont JK, van Schadewijk A, Gosman MME, Postma DS, Bajema IM, Timens W, Mauad T, Hiemstra PS [Contributors: Sterk PJ, et al -]] , Smoking cessation and bronchial epithelial remodelling in COPD: a cross-sectional study. RESP RES 2007;8:85 [PubMed]
Lapperre TS, Willems LNA, Timens W, Rabe KF, Hiemstra PS, Postma DS, Sterk PJ, Small airways dysfunction and neutrophilic inflammation in bronchial biopsies and BAL in COPD. CHEST 2007;131 (1):53-59 [PubMed]
Mauad T, Bel EH, Sterk PJ, Asthma therapy and airway remodeling. J ALLERGY CLIN IMMUN 2007;120 (5):997-1009; quiz 1010-1 [PubMed]
Nuijsink M, Hop WCJ, Sterk PJ, Duiverman EJ, de Jorgste JC, Long-term asthma treatment guided by airway hyperresponsiveness in children: a randomised controlled trial. EUR RESPIR J 2007;30 (3):457-466 [PubMed]
Nuijsink M, Hop WCJ, Sterk PJ, Duiverman EJ, Hiemstra PS, de Jongste JC, Urinary eosinophil protein X in children with atopic asthma. MEDIAT INFLAMM 2007;2007 (1):49240 [PubMed]
Ravensberg AJ, van Rensen ELJ, Grootendorst DC, de Kluijver J, Diamant Z, Ricciardolo FLM, Sterk PJ, Validated safety predictions of airway responses to house dust mite in asthma. CLIN EXP ALLERGY 2007;37 (1):100-107 [PubMed]
Slats AM, Janssen K, van Schadewijk A, van der Plas DT, Schot R, van den Aardweg LG, de Jongste JC, Hiemstra PS, Mauad T, Rabe KF, Sterk PJ, Bronchial inflammation and airway responses to deep inspiration in asthma and chronic obstructive pulmonary disease. AM J RESP CRIT CARE 2007;176 (2):121-128 [PubMed]
Sterk PJ. Asthma and respiratory pathogens in: van Dissel JT, editor. (Na)scholing infectieziekten 2007. Leiden: s.n.; 2007., p. 127-133
Sterk PJ. Nieuwe ontwikkelingen in de therapie van asthma en COPD in: van der Meer LW, van der Poel BNM, de Vries AD, Weber RFA, editors. Ontwikkelingen in de Geneeskunde 2007. Rotterdam: s.n.; 2007., p. 11-13
Sterk PJ. Towards molecular diagnosois in exhaled air in: Assendelft WJJ, Dolmans AJ, van Exter FMM, Groeneveld Y, Hoornweg J, de Meijer PHEM, editors. Vorderingen en praktijk. Leiden: s.n.; 2007., p. 235-240
Sterk PJ, Rabe KF, What else can you expect at www.erj.ersjournals.com?. EUR RESPIR J 2007;29 (1):1-3 [PubMed]
van der Meer V, van Stel HF, Detmar SB, Otten W, Sterk PJ, Sont JK, Internet-based self-management offers an opportunity to achieve better asthma control in adolescents. CHEST 2007;132 (1):112-119 [PubMed]
Fregonese L, van Veen HPAA, Sterk PJ, Stolk J, Ventilation inhomogeneity in alpha1-antitrypsin-deficient emphysema. EUR RESPIR J 2006;28 (2):323-329 [PubMed]
Gosman MME. From pathology to treatment in chronic obstructive pulmonary disease. Focus on inflammatory cells and airway hyperresponsiveness. s.l.: s.n.; 2006. -p. Proefschrift Rijksuniversiteit Groningen, UMCG. (Promotor(s): Sterk PJ, Postma DS, Timens W; copromotor(s): )
Kranenburg AR, Willems-Widyastuti A, Moori WJ, Sterk PJ, Alagappan VKT, de Boer WI, Sharma HS, Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease. AM J CLIN PATHOL 2006;126 (5):725-735 [PubMed]
Kunz LIZ, van Rensen ELJ, Sterk PJ, Inhaled hyaluronic acid against exercise-induced bronchoconstriction in asthma. PULM PHARMACOL THER 2006;19 (4):286-291 [PubMed]
Lapperre TS, Postma DS, Gosman MME, Snoeck-Stroband JB, ten Hacken NHT, Hiemstra PS, Timens W, Sterk PJ, Mauad T, Relation between duration of smoking cessation and bronchial inflammation in COPD. THORAX 2006;61 (2):115-121 [PubMed]
Rabe KF, Sterk PJ, Editing the ERJ: an observational study. EUR RESPIR J 2006;27 (1):1-2 [PubMed]
Ravensberg AJ, Luijk B, Westers P, Hiemstra PS, Sterk PJ, Lammers JW, Rabe KF, The effect of a single inhaled dose of a VLA-4 antagonist on allergen-induced airway responses and airway inflammation in patients with asthma. ALLERGY 2006;61 (9):1097-1103 [PubMed]
Slats AM, Sont JK, van Klink RHCJ, Bel EHD, Sterk PJ, Improvement in bronchodilation following deep inspiration after a course of high-dose oral prednisone in asthma. CHEST 2006;130 (1):58-65 [PubMed]
Snoeck-Stroband JB, Postma DS, Lapperre TS, Gosman MME, Thiadens HA, Kauffman HF, Sont JK, Jansen DF, Sterk PJ, Airway inflammation contributes to health status in COPD: a cross-sectional study. RESP RES 2006;7:140 [PubMed]
van der Meer V, Rikkers-Mutsaerts ERVM, Sterk PJ, Thiadens HA, Assendelft WJJ, Sont JK, Compliance and reliability of electronic PEF monitoring in adolescents with asthma. THORAX 2006;61 (5):457-458 [PubMed]
van Rensen ELJ. Airway inflammation in asthma. From concept to the clinic. s.l.: s.n.; 2006. 149p. Proefschrift Universiteit Leiden, Faculteit Geneeskunde. (Promotor(s): Sterk PJ, Rabe KF; copromotor(s): )
van Veen IH, Sterk PJ, Schot R, Gauw SA, Rabe KF, Bel EH, Alveolar nitric oxide versus measures of peripheral airway dysfunction in severe asthma. EUR RESPIR J 2006;27 (5):951-956 [PubMed]
Battaglia S, den Hertog H, Timmers MC, Lazeroms SPG, Vignola AM, Rabe KF, Bellia V, Hiemstra PS, Sterk PJ, Small airways function and molecular markers in exhaled air in mild asthma. THORAX 2005;60 (8):639-644 [PubMed]
Boot JD, Tarasevych S, Sterk PJ, Schoemaker RC, Wang L, Amin D, Cohen AF, Diamant Z, Reversal of the late asthmatic response increases exhaled nitric oxide. RESP MED 2005;99 (12):1591-1594 [PubMed]
Cohen J, Burggraaf J, Schoemaker RC, Sterk PJ, Cohen AF, Diamant Z, Relationship between airway responsiveness to neurokinin A and methacholine in asthma. PULM PHARMACOL THER 2005;18 (3):171-176 [PubMed]
de Kluijver J, Schrumpf JA, Evertse CE, Sont JK, Roughley PJ, Rabe KF, Hiemstra PS, Mauad T, Sterk PJ, Bronchial matrix and inflammation respond to inhaled steroids despite ongoing allergen exposure in asthma. CLIN EXP ALLERGY 2005;35 (10):1361-1369 [PubMed]
Diamant Z, Kuperus J, Baan R, Nietzmann K, Millet S, Mendes P, Miller B, Amin D, Rohatagi S, Sterk PJ, Hoogsteden HC, Prins JB, Effect of a very late antigen-4 receptor antagonist on allergen-induced airway responses and inflammation in asthma. CLIN EXP ALLERGY 2005;35 (8):1080-1087 [PubMed]
Fregonese L, Swan FJ, van Schadewijk A, Dolhnikoff M, Santos MA, Daha MR, Stolk J, Tschernig T, Sterk PJ, Hiemstra PS, Rabe KF, Mauad T, Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma. J ALLERGY CLIN IMMUN 2005;115 (6):1148-1154 [PubMed]
Kranenburg AR. Role of grrowth factors and extracellular matrix regulators in airway remodelling in COPD. s.l.: s.n.; 2005. -p. Proefschrift EUR, Erasmus Medisch Centrum. (Promotor(s): Sterk PJ, Saxena PR; copromotor(s): Sharma HS)
Kranenburg AR, de Boer WI, Alagappan VKT, Sterk PJ, Sharma HS, Enhanced bronchial expression of vascular endothelial growth factor and receptors (Flk-1 and Flt-1) in patients with chronic obstructive pulmonary disease. THORAX 2005;60 (2):106-113 [PubMed]
Kranenburg AR, Willems-Widyastuti A, Mooi WJ, Saxena PR, Sterk PJ, de Boer WI, Sharma HS, Chronic obstructive pulmonary disease is associated with enhanced bronchial expression of FGF-1, FGF-2, and FGFR-1. J PATHOL 2005;206 (1):28-38 [PubMed]
Kroeze S, van der Does AJW, Spinhoven P, Schot R, Sterk PJ, van den Aardweg JG, Automatic negative evaluation of suffocation sensations in individuals with suffocation fear. J ABNORM PSYCHOL 2005;114 (3):466-470 [PubMed]
Ravensberg AJ, Ricciardolo FLM, van Schadewijk A, Rabe KF, Sterk PJ, Hiemstra PS, Mauad T, Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge. J ALLERGY CLIN IMMUN 2005;115 (4):779-785 [PubMed]
Sterk PJ, Rabe KF, Serving researchers, the impact factor and other conflicts of interest. EUR RESPIR J 2005;25 (1):3-5 [PubMed]
ten Brinke A, Sterk PJ, Masclee AAM, Spinhoven P, Schmidt JT, Zwinderman AH, Rabe KF, Bel EH, Risk factors of frequent exacerbations in difficult-to-treat asthma. EUR RESPIR J 2005;26 (5):812-818 [PubMed]
van Rensen ELJ, Sont JK, Evertse CE, Willems LNA, Mauad T, Hiemstra PS, Sterk PJ, Bronchial CD8 cell infiltrate and lung function decline in asthma. AM J RESP CRIT CARE 2005;172 (7):837-841 [PubMed]
Lapperre TS, Snoeck-Stroband JB, Gosman MME, Stolk J, Sont JK, Jansen DF, Kerstjens HAM, Postma DS, Sterk PJ, Dissociation of lung function and airway inflammation in chronic obstructive pulmonary disease. AM J RESP CRIT CARE 2004;170 (5):499-504 [PubMed]
Rabe KF, Sterk PJ, Rapid, reliable and responsive: for whom?. EUR RESPIR J 2004;23 (1):1-2 [PubMed]
Ricciardolo FLM, Sterk PJ, Gaston B, Folkerts G, Nitric oxide in health and disease of the respiratory system. PHYSIOL REV 2004;84 (3):731-765 [PubMed]
Sterk PJ, Heterogeneity of airway hyperresponsiveness: time for unconventional, but traditional, studies. J APPL PHYSIOL 2004;96 (6):2017-2018 [PubMed]
Sterk PJ, Let's not forget: the GOLD criteria for COPD are based on post-bronchodilator FEV1. EUR RESPIR J 2004;23 (4):497-498 [PubMed]
Sterk PJ, Hiemstra PS, Eosinophil progenitors in sputum: throwing out the baby with the bath water?. AM J RESP CRIT CARE 2004;169 (5):549-550 [PubMed]
ten Brinke A, Zwinderman AH, Sterk PJ, Rabe KF, Bel EH, "Refractory" eosinophilic airway inflammation in severe asthma. AM J RESP CRIT CARE 2004;170 (12):1385-1386
ten Brinke A, Zwinderman AH, Sterk PJ, Rabe KF, Bel EH, "Refractory" eosinophilic airway inflammation in severe asthma - Effect of parenteral corticosteroids. AM J RESP CRIT CARE 2004;170 (6):601-605 [PubMed]
de Kluijver J, Evertse CE, Sont JK, Schrumpf JA, van Zeijl-van der Ham CJG, Dick CR, Rabe KF, Hiemstra PS, Sterk PJ, Are rhinovirus-induced airway responses in asthma aggravated by chronic allergen exposure?. AM J RESP CRIT CARE 2003;168 (10):1174-1180 [PubMed]
de Kluijver J, Grünberg K, Pons D, de Klerk EPA, Dick CR, Sterk PJ, Hiemstra PS, Interleukin-1beta and interleukin-1ra levels in nasal lavages during experimental rhinovirus infection in asthmatic and non-asthmatic subjects. CLIN EXP ALLERGY 2003;33 (10):1415-1418 [PubMed]
Grootendorst DC, Gauw SA, Baan R, Kelly J, Murdoch RD, Sterk PJ, Rabe KF, Does a single dose of the phosphodiesterase 4 inhibitor, cilomilast (15 mg), induce bronchodilation in patients with chronic obstructive pulmonary disease?. PULM PHARMACOL THER 2003;16 (2):115-120 [PubMed]
Grootendorst DC, Gauw SA, Benschop N, Sterk PJ, Hiemstra PS, Rabe KF, Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD). PULM PHARMACOL THER 2003;16 (6):341-347 [PubMed]
Kips JC, Anderson GP, Fredberg JJ, Herz U, Inman MD, Jordana M, Kemeny DM, Lötvall J, Pauwels RA, Plopper CG, Schmidt D, Sterk PJ, van Oosterhout AJM, Vargaftig BB, Chung KF, Murine models of asthma. EUR RESPIR J 2003;22 (2):374-382 [PubMed]
Ricciardolo FLM, Di Stefano A, van Krieken JHJM, Sont JK, van Schadewijk A, Rabe KF, Donner CF, Hiemstra PS, Sterk PJ, Mauad T, Proliferation and inflammation in bronchial epithelium after allergen in atopic asthmatics. CLIN EXP ALLERGY 2003;33 (7):905-911 [PubMed]
Ricciardolo FLM, Timmers MC, Sont JK, Folkerts G, Sterk PJ, Effect of bradykinin on allergen induced increase in exhaled nitric oxide in asthma. THORAX 2003;58 (10):840-845 [PubMed]
Sont JK, de Boer WI, van Schadewijk WAAM, Grünberg K, van Krieken JHJM, Hiemstra PS, Sterk PJ, Fully automated assessment of inflammatory cell counts and cytokine expression in bronchial tissue. AM J RESP CRIT CARE 2003;167 (11):1496-1503 [PubMed]
Sterk PJ, Rabe KF, You've got mail: erj@lumc.nl. EUR RESPIR J 2003;21 (1):1-2 [PubMed]
de Kluijver J, Evertse CE, Schrumpf JA, van der Veen H, Zwinderman AH, Hiemstra PS, Rabe KF, Sterk PJ, Asymptomatic worsening of airway inflammation during low-dose allergen exposure in asthma: protection by inhaled steroids. AM J RESP CRIT CARE 2002;166 (3):294-300 [PubMed]
de Kluijver J, Grünberg K, Sont JK, Hoogeveen M, van Schadewijk WAAM, de Klerk EPA, Dick CR, van Krieken JHJM, Sterk PJ, Rhinovirus infection in nonasthmatic subjects: effects on intrapulmonary airways. EUR RESPIR J 2002;20 (2):274-279 [PubMed]
Djukanović R, Sterk PJ, Fahy JV, Hargreave FE, Standardised methodology of sputum induction and processing. EUR RESPIR J 2002;20 (37):1s-2s [PubMed]
Hansel TT, Sterk PJ, Holgate ST, Barnes PJ, The trials and tribulations of anti-IL-5 em leader. J ALLERGY CLIN IMMUN 2002;109 (3):575-576 [PubMed]
Kips JC, Inman MD, Jayaram L, Bel EH, Parameswaran K, Pizzichini MMM, Pavord ID, Djukanović R, Hargreave FE, Sterk PJ, The use of induced sputum in clinical trials. EUR RESPIR J 2002;20 (37):47s-50s [PubMed]
Kranenburg AR, de Boer WI, van Krieken JHJM, Mooi WJ, Walters JE, Saxena PR, Sterk PJ, Sharma HS, Enhanced expression of fibroblast growth factors and receptor FGFR-1 during vascular remodeling in chronic obstructive pulmonary disease. AM J RESP CELL MOL 2002;27 (5):517-525 [PubMed]
Paggiaro PL, Chanez P, Holz O, Ind PW, Djukanović R, Maestrelli P, Sterk PJ, Sputum induction. EUR RESPIR J 2002;20 (37):3s-8s [PubMed]
Pavord ID, Sterk PJ, Hargreave FE, Kips JC, Inman MD, Louis R, Pizzichini MMM, Bel EH, Pin I, Grootendorst DC, Parameswaran K, Djukanović R, Clinical applications of assessment of airway inflammation using induced sputum. EUR RESPIR J 2002;20 (37):40s-43s [PubMed]
Pizzichini E, Pizzichini MMM, Leigh R, Djukanović R, Sterk PJ, Safety of sputum induction. EUR RESPIR J 2002;20 (37):9s-18s [PubMed]
Sterk PJ, Airway hyperresponsiveness: using bronchial challenge tests in research and management of asthma. J AEROSOL MED 2002;15 (2):123-129 [PubMed]
Sterk PJ, Koenderman L, Transcriptional machinery in asthma: closing the gap with clinical phenotypes. AM J RESP CRIT CARE 2002;166 (3):260-261 [PubMed]
ten Brinke A, Grootendorst DC, Schmidt JT, de Bruïne FT, van Buchem MA, Sterk PJ, Rabe KF, Bel EH, Chronic sinusitis in severe asthma is related to sputum eosinophilia. J ALLERGY CLIN IMMUN 2002;109 (4):621-626 [PubMed]
van Rensen ELJ, Hiemstra PS, Rabe KF, Sterk PJ, Assessment of microvascular leakage via sputum induction: the role of substance P and neurokinin A in patients with asthma. AM J RESP CRIT CARE 2002;165 (9):1275-1279 [PubMed]
Vignola AM, Rennar SI, Hargreave FE, Fah JV, Bonsignore MR, Djukanović R, Sterk PJ, Standardised methodology of sputum induction and processing. Future directions. EUR RESPIR J 2002;20 (37):51s-55s [PubMed]
Beasley R, Sterk PJ, Kerstjens HA, Decramer M, Comparative studies of inhaled corticosteroids in asthma. EUR RESPIR J 2001;17 (4):579-580 [PubMed]
Burggraaf J, Westendorp RG, in't Veen JC, Schoemaker RC, Sterk PJ, Cohen AF, Blauw GJ, Cardiovascular side effects of inhaled salbutamol in hypoxic asthmatic patients. THORAX 2001;56 (7):567-569 [PubMed]
Carlsen KH, Sterk PJ, Infection: friend or foe to the development of asthma?. EUR RESPIR J 2001;18 (5):744-747 [PubMed]
de Boer WI, Hiemstra PS, Sont JK, de Heer E, Rabe KF, van Krieken JH, Sterk PJ, Image analysis and quantification in lung tissue. CLIN EXP ALLERGY 2001;31 (3):504-508 [PubMed]
de Gouw HW, Marshall-Partridge SJ, van der Veen H, van den Aardweg JG, Hiemstra PS, Sterk PJ, Role of nitric oxide in the airway response to exercise in healthy and asthmatic subjects. J APPL PHYSIOL 2001;90 (2):586-592 [PubMed]
Grootendorst DC, Dahlén SE, van den Bos JW, Duiverman EJ, Veselic-Charvat M, Vrijlandt EJ, O'Sullivan S, Kumlin M, Sterk PJ, Roldaan AC, Benefits of high altitude allergen avoidance in atopic adolescents with moderate to severe asthma, over and above treatment with high dose inhaled steroids. CLIN EXP ALLERGY 2001;31 (3):400-408 [PubMed]
Grootendorst DC, Sterk PJ, Heijerman HG, Effect of oral prednisolone on the bronchoprotective effect of formoterol in patients with persistent asthma. EUR RESPIR J 2001;17 (3):374-379 [PubMed]
Grünberg K, Sharon RF, Sont JK, in 't Veen JC, van Schadewijk WA, de Klerk EP, Dick CR, van Krieken JH, Sterk PJ, Rhinovirus-induced airway inflammation in asthma: effect of treatment with inhaled corticosteroids before and during experimental infection. AM J RESP CRIT CARE 2001;164 (10 Part 1):1816-1822 [PubMed]
Ricciardolo FL, Timmers MC, Geppetti P, van Schadewijk A, Brahim JJ, Sont JK, de Gouw HW, Hiemstra PS, van Krieken JH, Sterk PJ, Allergen-induced impairment of bronchoprotective nitric oxide synthesis in asthma. J ALLERGY CLIN IMMUN 2001;108 (2):198-204 [PubMed]
ten Brinke A, de Lange C, Zwinderman AH, Rabe KF, Sterk PJ, Bel EH, Sputum induction in severe asthma by a standardized protocol: predictors of excessive bronchoconstriction. AM J RESP CRIT CARE 2001;164 (5):749-753 [PubMed]
ten Brinke A, van Dissel JT, Sterk PJ, Zwinderman AH, Rabe KF, Bel EH, Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection. J ALLERGY CLIN IMMUN 2001;107 (3):449-454 [PubMed]
ten Brinke A, Zwinderman AH, Sterk PJ, Rabe KF, Bel EH, Factors associated with persistent airflow limitation in severe asthma. AM J RESP CRIT CARE 2001;164 (5):744-748 [PubMed]
van Rensen EL, Stirling RG, Scheerens J, Staples K, Sterk PJ, Barnes PJ, Chung KF, Evidence for systemic rather than pulmonary effects of interleukin-5 administration in asthma. THORAX 2001;56 (12):935-940 [PubMed]
Chung KF, Sterk PJ, The airway smooth muscle cell: a major contributor to asthma?. EUR RESPIR J 2000;15 (3):438-439 [PubMed]
Crapo RO, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, MacIntyre NR, McKay RT, Wanger JS, Anderson SD, Cockcroft DW, Fish JE, Sterk PJ, Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. AM J RESP CRIT CARE 2000;161 (1):309-329 [PubMed]
Grünberg K, Sharon RF, Hiltermann TJ, Brahim JJ, Dick EC, Sterk PJ, van Krieken JH, Experimental rhinovirus 16 infection increases intercellular adhesion molecule-1 expression in bronchial epithelium of asthmatics regardless of inhaled steroid treatment. CLIN EXP ALLERGY 2000;30 (7):1015-1023 [PubMed]
Hofstra WB, Neijens HJ, Duiverman EJ, Kouwenberg JM, Mulder PG, Kuethe MC, Sterk PJ, Dose-responses over time to inhaled fluticasone propionate treatment of exercise- and methacholine-induced bronchoconstriction in children with asthma. PEDIATR PULM 2000;29 (6):415-423 [PubMed]
in 't Veen JC, Beekman AJ, Bel EH, Sterk PJ, Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes. AM J RESP CRIT CARE 2000;161 (6):1902-1906 [PubMed]
in 't Veen JC, Sterk PJ, Bel EH, Alternative strategies in the treatment of bronchial asthma. CLIN EXP ALLERGY 2000;30 (1):16-33 [PubMed]
Leckie MJ, ten Brinke A, Khan J, Diamant Z, O'Connor BJ, Walls CM, Mathur AK, Cowley HC, Chung KF, Djukanovic R, Hansel TT, Holgate ST, Sterk PJ, Barnes PJ, Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. LANCET 2000;356 (9248):2144-2148 [PubMed]
Magnussen H, Holz O, Sterk PJ, Hargreave FE, Noninvasive methods to measure airway inflammation: future considerations. EUR RESPIR J 2000;16 (6):1175-1179 [PubMed]
Cheung D, Sont JK, Sterk PJ, Clinical features of bronchial hyperresponsiveness. PULM PHARMACOL THER 1999;12 (2):91-96 [PubMed]
Chung KF, Godard P, Adelroth E, Ayres J, Barnes N, Barnes P, Bel E, Burney P, Chanez P, Connett G, Corrigan C, de Blic J, Fabbri L, Holgate ST, Ind P, Joos G, Kerstjens H, Leuenberger P, Lofdahl CG, McKenzie S, Magnussen H, Postma D, Saetta M, Salmeron S, Sterk P, Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respiratory Society. EUR RESPIR J 1999;13 (5):1198-1208 [PubMed]
de Gouw HW, Verbruggen MB, Twiss IM, Sterk PJ, Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. THORAX 1999;54 (11):1033-1035 [PubMed]
Diamant Z, Grootendorst DC, Veselic-Charvat M, Timmers MC, de Smet M, Leff JA, Seidenberg BC, Zwinderman AH, Peszek I, Sterk PJ, The effect of montelukast (MK-0476), a cysteinyl leukotriene receptor antagonist, on allergen-induced airway responses and sputum cell counts in asthma. CLIN EXP ALLERGY 1999;29 (1):42-51 [PubMed]
Grootendorst DC, van den Bos JW, Romeijn JJ, Veselic-Charvat M, Duiverman EJ, Vrijlandt EJ, Sterk PJ, Roldaan AC, Induced sputum in adolescents with severe stable asthma. Safety and the relationship of cell counts and eosinophil cationic protein to clinical severity. EUR RESPIR J 1999;13 (3):647-653 [PubMed]
Grünberg K, Sterk PJ, Rhinovirus infections: induction and modulation of airways inflammation in asthma. CLIN EXP ALLERGY 1999;29 (Suppl. 2):65-73 [PubMed]
Grünberg K, Timmers MC, de Klerk EP, Dick EC, Sterk PJ, Experimental rhinovirus 16 infection causes variable airway obstruction in subjects with atopic asthma. AM J RESP CRIT CARE 1999;160 (4):1375-1380 [PubMed]
Hiltermann JT, Lapperre TS, van Bree L, Steerenberg PA, Brahim JJ, Sont JK, Sterk PJ, Hiemstra PS, Stolk J, Ozone-induced inflammation assessed in sputum and bronchial lavage fluid from asthmatics: a new noninvasive tool in epidemiologic studies on air pollution and asthma. FREE RADICAL BIO MED 1999;27 (11-12):1448-1454 [PubMed]
in't Veen JC, Smits HH, Hiemstra PS, Zwinderman AE, Sterk PJ, Bel EH, Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal. AM J RESP CRIT CARE 1999;160 (1):93-99 [PubMed]
Ricciardolo FL, Rado V, Fabbri LM, Sterk PJ, Di Maria GU, Geppetti P, Bronchoconstriction induced by citric acid inhalation in guinea pigs: role of tachykinins, bradykinin, and nitric oxide. AM J RESP CRIT CARE 1999;159 (2):557-562 [PubMed]
Scheerens J, Folkerts G, van der Linde H, Sterk PJ, Conroy DM, Williams TJ, Nijkamp FP, Eotaxin levels and eosinophils in guinea pig broncho-alveolar lavage fluid are increased at the onset of a viral respiratory infection. CLIN EXP ALLERGY 1999;29 (Suppl. 2):74-77 [PubMed]
Sont JK, Willems LN, Bel EH, van Krieken JH, Vandenbroucke JP, Sterk PJ, Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group. AM J RESP CRIT CARE 1999;159 (4 Part 1):1043-1051 [PubMed]
Spinhoven P, Sterk PJ, van der Kamp L, Onstein EJ, The complex association of pulmonary function with panic disorder: a rejoinder to Ley (1998). J BEHAV THER EXP PSY 1999;30 (4):341-346 [PubMed]
Sterk PJ, Buist SA, Woolcock AJ, Marks GB, Platts-Mills TA, von Mutius E, Bousquet J, Frew AJ, Pauwels RA, Aït-Khaled N, Hill SL, Partridge MR, The message from the World Asthma Meeting. The Working Groups of the World Asthma Meeting, held in Barcelona, Spain, December 9-13, 1998. EUR RESPIR J 1999;14 (6):1435-1453 [PubMed]
Sterk PJ, de Gouw HW, Ricciardolo FL, Rabe KF, Exhaled nitric oxide in COPD: glancing through a smoke screen. THORAX 1999;54 (7):565-567 [PubMed]
van Rensen EL, Straathof KC, Veselic-Charvat MA, Zwinderman AH, Bel EH, Sterk PJ, Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma. THORAX 1999;54 (5):403-408 [PubMed]
van Wetering S, Sterk PJ, Rabe KF, Hiemstra PS, Defensins: key players or bystanders in infection, injury, and repair in the lung?. J ALLERGY CLIN IMMUN 1999;104 (6):1131-1138 [PubMed]
Cheung D, Wever AM, de GOEIJ JA, de Graaff CS, Steen H, Sterk PJ, Effects of theophylline on tolerance to the bronchoprotective actions of salmeterol in asthmatics in vivo. AM J RESP CRIT CARE 1998;158 (3):792-796 [PubMed]
de Gouw HW, Grünberg K, Schot R, Kroes AC, Dick EC, Sterk PJ, Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects. EUR RESPIR J 1998;11 (1):126-132 [PubMed]
de Gouw HW, Hendriks J, Woltman AM, Twiss IM, Sterk PJ, Exhaled nitric oxide (NO) is reduced shortly after bronchoconstriction to direct and indirect stimuli in asthma. AM J RESP CRIT CARE 1998;158 (1):315-319 [PubMed]
Diamant Z, Sterk PJ, Nieuwe therapie van asthma bronchiale: toepassing van leukotrieenreceptorantagonisten en leukotrieensyntheseremmers. NED TIJDSCHR GENEESKD 1998;142 (5):72-78 [PubMed]
Hiltermann TJ, Stolk J, van der Zee SC, Brunekreef B, de Bruijne CR, Fischer PH, Ameling CB, Sterk PJ, Hiemstra PS, van Bree L, Asthma severity and susceptibility to air pollution. EUR RESPIR J 1998;11 (3):686-693 [PubMed]
in 't Veen JC, Grootendorst DC, Bel EH, Smits HH, van der Keur M, Sterk PJ, Hiemstra PS, CD11b and L-selectin expression on eosinophils and neutrophils in blood and induced sputum of patients with asthma compared with normal subjects. CLIN EXP ALLERGY 1998;28 (5):606-615 [PubMed]
Pellegrino R, Sterk PJ, Sont JK, Brusasco V, Assessing the effect of deep inhalation on airway calibre: a novel approach to lung function in bronchial asthma and COPD. EUR RESPIR J 1998;12 (5):1219-1227 [PubMed]
Smits HH, Grünberg K, DeRijk RH, Sterk PJ, Hiemstra PS, Cytokine release and its modulation by dexamethasone in whole blood following exercise. CLIN EXP IMMUNOL 1998;111 (2):463-468 [PubMed]
Sterk PJ, Bronchoprovocation testing. SEMIN RESP CRIT CARE 1998;19 (4):317-324
Sterk PJ, Repeated low dose allergen exposure: a new investigational model of asthma as a persistent disease?. EUR RESPIR J 1998;11 (4):798-800 [PubMed]
Sterk PJ, The way forward in asthma: integrative physiology. CAN RESPIR J 1998;5 (Suppl. A):9A-13A [PubMed]
van Winden CM, Visser A, Hop W, Sterk PJ, Beckers S, de Jongste JC, Effects of flutter and PEP mask physiotherapy on symptoms and lung function in children with cystic fibrosis. EUR RESPIR J 1998;12 (1):143-147 [PubMed]
Veen JC, Smits HH, Ravensberg AJ, Hiemstra PS, Sterk PJ, Bel EH, Impaired perception of dyspnea in patients with severe asthma. Relation to sputum eosinophils. AM J RESP CRIT CARE 1998;158 (4):1134-1141 [PubMed]
Westedt ML, Hazes JM, Breedveld FC, Sterk PJ, Dijkman JH, Cigarette smoking and pulmonary diffusion defects in rheumatoid arthritis. RHEUMATOL INT 1998;18 (1):1-4 [PubMed]
Booms P, Cheung D, Timmers MC, Zwinderman AH, Sterk PJ, Protective effect of inhaled budesonide against unlimited airway narrowing to methacholine in atopic patients with asthma. J ALLERGY CLIN IMMUN 1997;99 (3):330-337 [PubMed]
Brand PL, Duiverman EJ, Postma DS, Waalkens HJ, Kerrebijn KF, van Essen-Zandvliet EE [Contributors: Pouw EM, Schoonbrood DF, Roos CM, Jansen HM, Sterk PJ, et al -]] , Peak flow variation in childhood asthma: relationship to symptoms, atopy, airways obstruction and hyperresponsiveness. EUR RESPIR J 1997;10 (6):1242-1247 [PubMed]
Cheung D, Schot R, Zwinderman AH, Zagers H, Dijkman JH, Sterk PJ, Relationship between loss in parenchymal elastic recoil pressure and maximal airway narrowing in subjects with alpha1-antitrypsin deficiency. AM J RESP CRIT CARE 1997;155 (1):135-140 [PubMed]
Diamant Z, Hiltermann JT, van Rensen EL, Callenbach PM, Veselic-Charvat M, van der Veen H, Sont JK, Sterk PJ, The effect of inhaled leukotriene D4 and methacholine on sputum cell differentials in asthma. AM J RESP CRIT CARE 1997;155 (4):1247-1253 [PubMed]
Grashoff WF, Sont JK, Sterk PJ, Hiemstra PS, de Boer WI, Stolk J, Han J, van Krieken JM, Chronic obstructive pulmonary disease: role of bronchiolar mast cells and macrophages. AM J PATHOL 1997;151 (6):1785-1790 [PubMed]
Grootendorst DC, Sont JK, Willems LN, Kluin-Nelemans JC, van Krieken JH, Veselic-Charvat M, Sterk PJ, Comparison of inflammatory cell counts in asthma: induced sputum vs bronchoalveolar lavage and bronchial biopsies. CLIN EXP ALLERGY 1997;27 (7):769-779 [PubMed]
Grünberg K, Kuijpers EA, de Klerk EP, de Gouw HW, Kroes AC, Dick EC, Sterk PJ, Effects of experimental rhinovirus 16 infection on airway hyperresponsiveness to bradykinin in asthmatic subjects in vivo. AM J RESP CRIT CARE 1997;155 (3):833-838 [PubMed]
Grünberg K, Smits HH, Timmers MC, de Klerk EP, Dolhain RJ, Dick EC, Hiemstra PS, Sterk PJ, Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects. AM J RESP CRIT CARE 1997;156 (2 Part 1):609-616 [PubMed]
Grünberg K, Timmers MC, Smits HH, de Klerk EP, Dick EC, Spaan WJ, Hiemstra PS, Sterk PJ, Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in vivo. CLIN EXP ALLERGY 1997;27 (1):36-45 [PubMed]
Hofstra WB, Sont JK, Sterk PJ, Neijens HJ, Kuethe MC, Duiverman EJ, Sample size estimation in studies monitoring exercise-induced bronchoconstriction in asthmatic children. THORAX 1997;52 (8):739-741 [PubMed]
Sont JK, van Krieken JH, van Klink HC, Roldaan AC, Apap CR, Willems LN, Sterk PJ, Enhanced expression of neutral endopeptidase (NEP) in airway epithelium in biopsies from steroid- versus nonsteroid-treated patients with atopic asthma. AM J RESP CELL MOL 1997;16 (5):549-556 [PubMed]
Sont JK, Willems LN, Evertse CE, Hooijer R, Sterk PJ, van Krieken JH, Repeatability of measures of inflammatory cell number in bronchial biopsies in atopic asthma. EUR RESPIR J 1997;10 (11):2602-2608 [PubMed]
Spinhoven P, van Peski-Oosterbaan AS, van der Does AJ, Willems LN, Sterk PJ, Association of anxiety with perception of histamine induced bronchoconstriction in patients with asthma. THORAX 1997;52 (2):149-152 [PubMed]
Sterk PJ, Non-invasive monitoring of bronchial inflammation in asthma. SCHWEIZ MED WSCHR 1997;127 (41):1686-1692 [PubMed]
Sterk PJ, Larsson K, Naeije R, Costabel U, Publishing collaborative studies between academics and industry. EUR RESPIR J 1997;10 (11):2441-2442 [PubMed]
de Gouw HW, Diamant Z, Kuijpers EA, Sont JK, Sterk PJ, Role of neutral endopeptidase in exercise-induced bronchoconstriction in asthmatic subjects. J APPL PHYSIOL 1996;81 (2):673-678 [PubMed]
Diamant Z, Timmers MC, van der Veen H, Page CP, van der Meer FJ, Sterk PJ, Effect of inhaled heparin on allergen-induced early and late asthmatic responses in patients with atopic asthma. AM J RESP CRIT CARE 1996;153 (6 Part 1):1790-1795 [PubMed]
Diamant Z, van der Veen H, Kuijpers EA, Bakker PF, Sterk PJ, The effect of inhaled thiorphan on allergen-induced airway responses in asthmatic subjects. CLIN EXP ALLERGY 1996;26 (5):525-532 [PubMed]
Hofstra WB, Sterk PJ, Neijens HJ, Kouwenberg JM, Mulder PG, Duiverman EJ, Occurrence of a late response to exercise in asthmatic children: multiple regression approach using time-matched baseline and histamine control days. EUR RESPIR J 1996;9 (7):1348-1355 [PubMed]
in 't Veen JC, de Gouw HW, Smits HH, Sont JK, Hiemstra PS, Sterk PJ, Bel EH, Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma. EUR RESPIR J 1996;9 (12):2441-2447 [PubMed]
Overbeek SE, Kerstjens HA, Bogaard JM, Mulder PG, Postma DS [Contributors: Pouw EM, Schoonbrood DF, Roos CM, Jansen HM, Sterk PJ, et al -]] , Is delayed introduction of inhaled corticosteroids harmful in patients with obstructive airways disease (asthma and COPD)?. CHEST 1996;110 (1):35-41 [PubMed]
Schreur HJ, Diamant Z, Vanderschoot J, Zwinderman AH, Dijkman JH, Sterk PJ, Lung sounds during allergen-induced asthmatic responses in patients with asthma. AM J RESP CRIT CARE 1996;153 (5):1474-1480 [PubMed]
Sont JK, Han J, van Krieken JM, Evertse CE, Hooijer R, Willems LN, Sterk PJ, Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids. THORAX 1996;51 (5):496-502 [PubMed]
Sterk PJ, Bronchial hyperresponsiveness: definition and terminology. PEDIAT ALLERG IMM-UK 1996;7 (9 Suppl):7-9 [PubMed]
van Peski-Oosterbaan AS, Spinhoven P, van der Does AJ, Willems LN, Sterk PJ, Is there a specific relationship between asthma and panic disorder?. BEHAV RES THER 1996;34 (4):333-340 [PubMed]
Bogaard JM, Overbeek SE, Verbraak AF, Vons C, Folgering HT, van der Mark TW, Roos CM, Sterk PJ, Pressure-volume analysis of the lung with an exponential and linear-exponential model in asthma and COPD. Dutch CNSLD Study Group. EUR RESPIR J 1995;8 (9):1525-1531 [PubMed]
Cheung D, Dick EC, Timmers MC, de Klerk EP, Spaan WJ, Sterk PJ, Rhinovirus inhalation causes long-lasting excessive airway narrowing in response to methacholine in asthmatic subjects in vivo. AM J RESP CRIT CARE 1995;152 (5 Part 1):1490-1496 [PubMed]
Diamant Z, Timmers MC, van der Veen H, Friedman BS, de Smet M, Depré M, Hilliard D, Bel EH, Sterk PJ, The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo. J ALLERGY CLIN IMMUN 1995;95 (1 Part 1):42-51 [PubMed]
Hiltermann TJ, Stolk J, Hiemstra PS, Fokkens PH, Rombout PJ, Sont JK, Sterk PJ, Dijkman JH, Effect of ozone exposure on maximal airway narrowing in non-asthmatic and asthmatic subjects. CLIN SCI 1995;89 (6):619-624 [PubMed]
Hofstra WB, Sterk PJ, Neijens HJ, Kouwenberg JM, Duiverman EJ, Prolonged recovery from exercise-induced asthma with increasing age in childhood. PEDIATR PULM 1995;20 (3):177-183 [PubMed]
Kerstjens HA, Schouten JP, Brand PL, Schoonbrood DF, Sterk PJ, Postma DS, Importance of total serum IgE for improvement in airways hyperresponsiveness with inhaled corticosteroids in asthma and chronic obstructive pulmonary disease. The Dutch CNSLD Study Group. AM J RESP CRIT CARE 1995;151 (2 Part 1):360-368 [PubMed]
Schreur HJ, Vanderschoot J, Zwinderman AH, Dijkman JH, Sterk PJ, The effect of methacholine-induced acute airway narrowing on lung sounds in normal and asthmatic subjects. EUR RESPIR J 1995;8 (2):257-265 [PubMed]
Sont JK, Booms P, Bel EH, Vandenbroucke JP, Sterk PJ, The severity of breathlessness during challenges with inhaled methacholine and hypertonic saline in atopic asthmatic subjects. The relationship with deep breath-induced bronchodilation. AM J RESP CRIT CARE 1995;152 (1):38-44 [PubMed]
Spinhoven P, Onstein EJ, Sterk PJ, Pulmonary function in panic disorder: evidence against the dyspnea-fear theory. BEHAV RES THER 1995;33 (4):457-460 [PubMed]
Sterk PJ, The place of airway hyperresponsiveness in the asthma phenotype. CLIN EXP ALLERGY 1995;25 (Suppl. 2):8-11; discussion 17-8 [PubMed]
Cheung D, van der Veen H, den Hartigh J, Dijkman JH, Sterk PJ, Effects of inhaled substance P on airway responsiveness to methacholine in asthmatic subjects in vivo. J APPL PHYSIOL 1994;77 (3):1325-1332 [PubMed]
Diamant Z, Lammers JWJ, Sterk PJ, LEUKOTRIENE RECEPTOR ANTAGONISTS AND BIOSYNTHESIS INHIBITORS IN ASTHMA - AN UPDATE. CLIN IMMUNOTHER 1994;2 (3):220-232
Diamant Z, Timmers MC, van der Veen H, Booms P, Sont JK, Sterk PJ, Effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responsiveness to leukotriene D4 in normal and asthmatic subjects. EUR RESPIR J 1994;7 (3):459-466 [PubMed]
Kerstjens HA, Brand PL, de Jong PM, Koëter GH, Postma DS [Contributors: Pouw EM, Schoonbrood DF, Roos CM, Jansen HM, Sterk PJ, et al -]] , Influence of treatment on peak expiratory flow and its relation to airway hyperresponsiveness and symptoms. THORAX 1994;49 (11):1109-1115 [PubMed]
Quanjer PH, Tammeling GJ, Cotes JE, Fabbri LM, Matthys H, Pedersen OF, Peslin R, Roca J, Sterk PJ, Ulmer WT, Symboles, abréviations et unités. Groupe de travail sur la standardisation des épreuves fonctionnelles respiratoires. Communauté Européenne du Charbon et de l'Acier. Position officielle del'European Respiratory Society. REV MAL RESPIR 1994;11 (Suppl. 3):85-100 [PubMed]
Schreur HJ, Vanderschoot J, Zwinderman AH, Dijkman JH, Sterk PJ, Abnormal lung sounds in patients with asthma during episodes with normal lung function. CHEST 1994;106 (1):91-99 [PubMed]
Sterk PJ, Farewell to "CARA"?. NETH J MED 1994;45 (4):139-144 [PubMed]
Sterk PJ, Improving asthma treatment: the physiological message. EUR RESPIR J 1994;7 (2):220-222 [PubMed]
Sterk PJ, Fabbri LM, Quanjer PH, Cockcroft DW, O'Byrne PM, Anderson SD, Juniper EF, Malo JL, Réactivité des voies aériennes. Tests de provocation normalisés chez l'adulte: stimuli pharmacologiques, physiques et sensibilisants. Groupe de travail sur la standardisation des épreuves fonctionnelles respiratoires. Communauté Européenne du Charbon et de l'Acier. Position officielle de l'European Respiratory Society. REV MAL RESPIR 1994;11 (Suppl. 3):53-83 [PubMed]
Barnes NC, Marone G, Di Maria GU, Visser S, Utama I, Payne SL [Contributors: Sterk PJ, et al -]] , A comparison of fluticasone propionate, 1 mg daily, with beclomethasone dipropionate, 2 mg daily, in the treatment of severe asthma. International Study Group. EUR RESPIR J 1993;6 (6):877-885 [PubMed]
Brand PL, Kerstjens HA, Jansen HM, Kauffman HF, de Monchy JG [Contributors: Pouw EM, Schoonbrood DF, Roos CM, Jansen HM, Sterk PJ, et al -]] , Interpretation of skin tests to house dust mite and relationship to other allergy parameters in patients with asthma and chronic obstructive pulmonary disease. J ALLERGY CLIN IMMUN 1993;91 (2):560-570 [PubMed]
Cheung D, Timmers MC, Zwinderman AH, den Hartigh J, Dijkman JH, Sterk PJ, Neutral endopeptidase activity and airway hyperresponsiveness to neurokinin A in asthmatic subjects in vivo. AM REV RESPIR DIS 1993;148 (6 Part 1):1467-1473 [PubMed]
Friedman BS, Bel EH, Buntinx A, Tanaka W, Han YH, Shingo S, Spector R, Sterk P, Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses. AM REV RESPIR DIS 1993;147 (4):839-844 [PubMed]
Quanjer PH, Tammeling GJ, Cotes JE, Fabbri LM, Matthys H, Pedersen OF, Peslin R, Roca J, Sterk PJ, Ulmer WT, Symbols, abbreviations and units. Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. EUR RESPIR J 1993;6 (16):85-100 [PubMed]
Sont JK, Booms P, Bel EH, Vandenbroucke JP, Sterk PJ, The determinants of airway hyperresponsiveness to hypertonic saline in atopic asthma in vivo. Relationship with sub-populations of peripheral blood leucocytes. CLIN EXP ALLERGY 1993;23 (8):678-688 [PubMed]
Spinhoven P, Onstein EJ, Sterk PJ, Hyperventilatie: geen oorzaak van paniekaanvallen. NED TIJDSCHR GENEESKD 1993;137 (45):2315-2318 [PubMed]
Spinhoven P, Onstein EJ, Sterk PJ, Le Haen-Versteijnen D, Discordance between symptom and physiological criteria for the hyperventilation syndrome. J PSYCHOSOM RES 1993;37 (3):281-289 [PubMed]
Spinhoven P, Onstein EJ, Sterk PJ, Le Haen-Versteijnen D, Hyperventilation and panic attacks in general hospital patients. GEN HOSP PSYCHIAT 1993;15 (3):148-154 [PubMed]
Sterk PJ, Bronchial hyperresponsiveness today. RESP MED 1993;87 (Suppl. B):27-29 [PubMed]
Sterk PJ, Virus-induced airway hyperresponsiveness in man. EUR RESPIR J 1993;6 (6):894-902 [PubMed]
Sterk PJ, Fabbri LM, Quanjer PH, Cockcroft DW, O'Byrne PM, Anderson SD, Juniper EF, Malo JL, Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. EUR RESPIR J SUPPL 1993;16:53-83 [PubMed]
van Veen S, Peeters AJ, Sterk PJ, Breedveld FC, The "shrinking lung syndrome" in SLE, treatment with theophylline. CLIN RHEUMATOL 1993;12 (4):462-465 [PubMed]
Waalkens HJ, van Essen-Zandvliet EE, Hughes MD, Gerritsen J, Duiverman EJ, Knol K, Kerrebijn KF [Contributors: Pouw EM, Schoonbrood DF, Roos CM, Jansen HM, Sterk PJ, et al -]] , Cessation of long-term treatment with inhaled corticosteroid (budesonide) in children with asthma results in deterioration. AM REV RESPIR DIS 1993;148 (5):1252-1257 [PubMed]
Brand PL, Kerstjens HA, Postma DS, Sterk PJ, Quanjer PH, Sluiter HJ, Dijkman JH, van Herwaarden CL, Hilvering C, Jansen HM, Long-term multicentre trial in chronic nonspecific lung disease: methodology and baseline assessment in adult patients. Dutch CNSLD Study Group. EUR RESPIR J 1992;5 (1):21-31 [PubMed]
Cheung D, Bel EH, den Hartigh J, Dijkman JH, Sterk PJ, The effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responses to neurokinin A in normal humans in vivo. AM REV RESPIR DIS 1992;145 (6):1275-1280 [PubMed]
Cheung D, Timmers MC, Zwinderman AH, Bel EH, Dijkman JH, Sterk PJ, Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. NEW ENGL J MED 1992;327 (17):1198-1203 [PubMed]
Dekker FW, Schrier AC, Sterk PJ, Dijkman JH, Validity of peak expiratory flow measurement in assessing reversibility of airflow obstruction. THORAX 1992;47 (3):162-166 [PubMed]
Heijerman HG, Bakker W, Sterk PJ, Dijkman JH, Long-term effects of exercise training and hyperalimentation in adult cystic fibrosis patients with severe pulmonary dysfunction. INT J REHABIL RES 1992;15 (3):252-257 [PubMed]
Merkus PJ, van Essen-Zandvliet EE, Parlevliet E, Borsboom G, Sterk PJ, Kerrebijn KF, Quanjer PH, Changes of nebulizer output over the years. EUR RESPIR J 1992;5 (4):488-491 [PubMed]
Osanto S, Bukman A, van Hoek F, Sterk PJ, de Laat JA, Hermans J, Long-term effects of chemotherapy in patients with testicular cancer. J CLIN ONCOL 1992;10 (4):574-579 [PubMed]
Schreur HJ, Sterk PJ, Vanderschoot J, van Klink HC, van Vollenhoven E, Dijkman JH, Lung sound intensity in patients with emphysema and in normal subjects at standardised airflows. THORAX 1992;47 (9):674-679 [PubMed]
Sont JK, Bel EH, Dijkman JH, Sterk PJ, The long-term effect of nedocromil sodium on the maximal degree of airway narrowing to methacholine in atopic asthmatic subjects. CLIN EXP ALLERGY 1992;22 (5):554-560 [PubMed]
Speelberg B, Folgering HT, Sterk PJ, van Herwaarden CL, Longfunctie van volwassen patiënten met asthma bronchiale of chronische obstructieve longaandoening, vóór en na een verblijf van 3 maanden in het Nederlands Astmacentrum Davos. NED TIJDSCHR GENEESKD 1992;136 (10):469-473 [PubMed]
Spinhoven P, Onstein EJ, Sterk PJ, Le Haen-Versteijnen D, The hyperventilation provocation test in panic disorder. BEHAV RES THER 1992;30 (5):453-461 [PubMed]
Sterk PJ, The determinants of the severity of acute airway narrowing in asthma and COPD. RESP MED 1992;86 (5):391-396 [PubMed]
Sterk PJ, Bel EH, Vandenbroucke JP, Astma: theorie en praktijk, anno 1992. NED TIJDSCHR GENEESKD 1992;136 (10):451-455 [PubMed]
Bel EH, Timmers MC, Zwinderman AH, Dijkman JH, Sterk PJ, The effect of inhaled corticosteroids on the maximal degree of airway narrowing to methacholine in asthmatic subjects. AM REV RESPIR DIS 1991;143 (1):109-113 [PubMed]
Bel EH, Zwinderman AH, Timmers MC, Dijkman JH, Sterk PJ, The protective effect of a beta 2 agonist against excessive airway narrowing in response to bronchoconstrictor stimuli in asthma and chronic obstructive lung disease. THORAX 1991;46 (1):9-14 [PubMed]
de Pee S, Timmers MC, Hermans J, Duiverman EJ, Sterk PJ, Comparison of maximal airway narrowing to methacholine between children and adults. EUR RESPIR J 1991;4 (4):421-428 [PubMed]
Heijerman HG, Bakker W, Sterk PJ, Dijkman JH, Oxygen-assisted exercise training in adult cystic fibrosis patients with pulmonary limitation to exercise. INT J REHABIL RES 1991;14 (2):101-115 [PubMed]
Sterk PJ, Bel EH, The shape of the dose-response curve to inhaled bronchoconstrictor agents in asthma and in chronic obstructive pulmonary disease. AM REV RESPIR DIS 1991;143 (6):1433-1437 [PubMed]
Bel EH, Timmers MC, Dijkman JH, Stahl EG, Sterk PJ, The effect of an inhaled leukotriene antagonist, L-648,051, on early and late asthmatic reactions and subsequent increase in airway responsiveness in man. J ALLERGY CLIN IMMUN 1990;85 (6):1067-1075 [PubMed]
Bel EH, Timmers MC, Hermans J, Dijkman JH, Sterk PJ, The long-term effects of nedocromil sodium and beclomethasone dipropionate on bronchial responsiveness to methacholine in nonatopic asthmatic subjects. AM REV RESPIR DIS 1990;141 (1):21-28 [PubMed]
Willems LN, Kramps JA, Stijnen T, Sterk PJ, Weening JJ, Dijkman JH, Relation between small airways disease and parenchymal destruction in surgical lung specimens. THORAX 1990;45 (2):89-94 [PubMed]
Bel EH, van der Veen H, Dijkman JH, Sterk PJ, The effect of inhaled budesonide on the maximal degree of airway narrowing to leukotriene D4 and methacholine in normal subjects in vivo. AM REV RESPIR DIS 1989;139 (2):427-431 [PubMed]
Padberg GW, Wintzen AR, Giesberts MA, Sterk PJ, Molenaar AJ, Hermans J, Effects of a high-protein diet in acid maltase deficiency. J NEUROL SCI 1989;90 (1):111-117 [PubMed]
Sterk PJ, Bel EH, Bronchial hyperresponsiveness: the need for a distinction between hypersensitivity and excessive airway narrowing. EUR RESPIR J 1989;2 (3):267-274 [PubMed]
Willems LN, Kramps JA, Stijnen T, Sterk PJ, Weening JJ, Dijkman JH, Antileukoprotease-containing bronchiolar cells. Relationship with morphologic disease of small airways and parenchyma. AM REV RESPIR DIS 1989;139 (5):1244-1250 [PubMed]
de Jongste JC, Sterk PJ, Willems LN, Mons H, Timmers MC, Kerrebijn KF, Comparison of maximal bronchoconstriction in vivo and airway smooth muscle responses in vitro in nonasthmatic humans. AM REV RESPIR DIS 1988;138 (2):321-326 [PubMed]
Sterk PJ, Timmers MC, Bel EH, Dijkman JH, The combined effects of histamine and methacholine on the maximal degree of airway narrowing in normal humans in vivo. EUR RESPIR J 1988;1 (1):34-40 [PubMed]
Bel EH, van der Veen H, Kramps JA, Dijkman JH, Sterk PJ, Maximal airway narrowing to inhaled leukotriene D4 in normal subjects. Comparison and interaction with methacholine. AM REV RESPIR DIS 1987;136 (4):979-984 [PubMed]
Verhagen J, Bel EH, Kijne GM, Sterk PJ, Bruynzeel PL, Veldink GA, Vliegenthart JF, The excretion of leukotriene E4 into urine following inhalation of leukotriene D4 by human individuals. BIOCHEM BIOPH RES CO 1987;148 (2):864-868 [PubMed]
Sterk PJ, Timmers MC, Dijkman JH, Maximal airway narrowing in humans in vivo. Histamine compared with methacholine. AM REV RESPIR DIS 1986;134 (4):714-718 [PubMed]
Verboon JM, Bakker W, Sterk PJ, The value of the forced expiration technique with and without postural drainage in adults with cystic fibrosis. EUR J RESPIR DIS 1986;69 (3):169-174 [PubMed]
Hargreave FE, Ramsdale EH, Sterk PJ, Juniper EF, Advances in the use of inhalation provocation tests in clinical evaluation. CHEST 1985;87 (1 Suppl):32S-35S [PubMed]
Hargreave FE, Sterk PJ, Ramsdale EH, Dolovich J, Zamel N, INHALATION CHALLENGE TESTS AND AIRWAY RESPONSIVENESS IN MAN. CHEST 1985;97 (5):S202-S206
Sterk PJ, Daniel EE, Zamel N, Hargreave FE, Limited bronchoconstriction to methacholine using partial flow-volume curves in nonasthmatic subjects. AM REV RESPIR DIS 1985;132 (2):272-277 [PubMed]
Sterk PJ, Daniel EE, Zamel N, Hargreave FE, Limited maximal airway narrowing in nonasthmatic subjects. Role of neural control and prostaglandin release. AM REV RESPIR DIS 1985;132 (4):865-870 [PubMed]
Sterk PJ, Plomp A, van de Vate JF, Quanjer PH, Physical properties of aerosols produced by several jet- and ultrasonic nebulizers. BULL EUR PHYSIOPATHOL RESPIR 1984;20 (1):65-72 [PubMed]
Sterk PJ, Plomp A, Crobach MJ, van de Vate JF, Quanjer PH, The physical properties of a jet-nebulizer and their relevance for the histamine provocation test. BULL EUR PHYSIOPATHOL RESPIR 1983;19 (1):27-36 [PubMed]
Hermans J, van Zomeren B, Raatgever JW, Sterk PJ, Habbema JD, Use of posterior probabilities to evaluate methods of discriminant analysis. METHOD INFORM MED 1981;20 (4):207-212 [PubMed]
Sterk PJ, Quanjer PH, van Zomeren BC, Wise ME, van der Lende R, The single breath nitrogen test in epidemiological surveys; an appraisal. BULL EUR PHYSIOPATHOL RESPIR 1981;17 (3):381-397 [PubMed]
Sterk PJ, Quanjer PH, van Zomeren BC, Wise ME, van der Lende R, Towards identifying the susceptible smoker. BULL EUR PHYSIOPATHOL RESPIR 1981;17 (3):399-310 [PubMed]
Sterk PJ, Quanjer PH, van der Maas LL, Wise ME, van der Lende R, The validity of the single-breath nitrogen determination of residual volume. BULL EUR PHYSIOPATHOL RESPIR 1980;16 (2):195-213 [PubMed]
Key publications

Yick CY, Zwinderman AH, Kunst PW, Grünberg K, Mauad T, Fluiter K, Bel EH, Lutter R, Baas F, Sterk PJ, Glucocorticoid-induced changes in gene expression of airway smooth muscle in patients with asthma. AM J RESP CRIT CARE 2013;187 (10):1076-1084 [PubMed]
Fens N, van der Sluijs KF, van de Pol MA, Dijkhuis A, Smids BS, van der Zee JS, Lutter R, Zwinderman AH, Sterk PJ [Contributors: Berger M, Yick D, Wagener A, Amelink M, Reesink H, Bresser P, Kunst P, Venekamp L, Majoor C, van Steenwijk R, Jonkers R]] , Electronic Nose Identifies Bronchoalveolar Lavage Fluid Eosinophils in Asthma. AM J RESP CRIT CARE 2015;191 (9):1086-1088 [PubMed]
Boots AW, Bos LD , van der Schee MP, van Schooten FJ, Sterk PJ, Exhaled Molecular Fingerprinting in Diagnosis and Monitoring: Validating Volatile Promises. TRENDS MOL MED 2015;21 (10):633-644 [PubMed]
Thamrin C, Frey U, Kaminsky DA, Reddel HK, Seely AJE, Suki B, Sterk PJ, Systems Biology and Clinical Practice in Respiratory Medicine. The Twain Shall Meet. AM J RESP CRIT CARE 2016;194 (9):1053-1061 [PubMed]
Postma DS, Wijkstra PJ, Hiemstra PS, Melgert BN, Braunstahl GJ, Hylkema MN, Sterk PJ, The Dutch National Program for Respiratory Research. LANCET RESP MED 2016;4 (5):356-357 [PubMed]


All Publications

Curriculum Vitae

CURRICULUM VITA

 

February 21, 2014

 

Identity
-  Name:  Pieter Jan Sterk
- Date of birth March: 31st, 1951
- Nationality:  Dutch
- Address:  Lagewaard 21, NL-2396 AV Koudekerk aan den Rijn
Affiliation
- Institute:  Academic Medical Centre, University of Amsterdam
- Address:  Dept. of Respiratory Medicine, F5-259, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, NL-1105 AZ Amsterdam
- Telephone: +31 20 566 4356
- Fax: +31 20 566 9001
- eMail: p.j.sterk@amc.nl

 

Training
- MD: Leiden University, 1976
- PhD: Leiden University, 1981
- Clinical Physiologist Leiden University, 1981

 

Positions
- 1976-1981: Research Fellow Dept. of Physiology, Head Prof. Ph.H. Quanjer, Leiden University, The Netherlands
- 1983-1984: Clinical Fellow Dept. of Respirology, Prof. F.E. Hargreave, McMaster University, Hamilton, Ontario, Canada
- 1981-1985: University Lecturer Dept. of Pulmonology, Head Prof. J.H. Dijkman, Leiden University Medical Center
- 1986-1995: Associate Professor Dept. of Pulmonology, Leiden University Medical Center
- 1996- present: Full Professor Dept. of Pulmonology, Head Prof. C. Taube, Leiden University Medical Center
- 2007-present: Full Professor Dept. of Respiratory Medicine, Head Prof. E.H. Bel, Academic Medical Centre, University of Amsterdam

- 2016 onwards: Emeritus  

 

Current additional activities
1. Coordinator of EU Innovative Medicines Initiative (IMI) consortium U-BIOPRED (2009-2015)
2. Past Chief Editor of the European Respiratory Journal (impact 6.1)
3. Member of the Editorial Board of the American Journal of Respiratory and Critical Care Medicine (Impact 11.0)
4, Chair of the Koninklijke Maatschappij voor Natuurkunde ‘Diligentia’ The Hague

 

Awards and rankings

 

  1. Recipient of the 2010 Karolinska Institute Annual Clinical Science Lecture Award
  2. The 2005 ‘Sadoul Award’ by the European Respiratory Society for ‘Worldwide Recognition of Scientific Career’
  3. Elsevier citation ranking 2005: 3rd highest citing international medical publication from The Netherlands (2001-2004)                                                              

Funding
- Cumulative number of public, competitive grants: 52
- Cumulative number of industrial grants: 8

 

- Recipient, PI and Coordinator of EU IMI grant on Severe Asthma U-BIOPRED 2009-2015  (26.9 Million Euro’s)

 

- Recipient Dutch Public Charity grant Vriendenlotery (400 kEuro's)

 

Publications in peer review journals
- Number of peer review papers in PubMed since 1980: 396
- Average citations per paper: 33

 

- H-index for scientific productivity (Ball Ph. Nature 2005;436:900) : 69

 

Research programmes

Pathophysiology and phenotyping of asthma and COPD

The research program focuses on the pathogenesis, phenotyping and early tailored interventions of inflammatory airway diseases, which includes asthma and chronic obstructive pulmonary disease (COPD). The overarching aim is to introduce precision medicine to the clinic.

The research approach is an integrative one, linking the major clinical problems to individual pathophysiological determinants at the molecular, cellular and organ level. This requires connections between high-dimensional molecular profiling, modern pathology and biophysics in patients in vivo. This novel medical concept is called 'systems medicine'.

The main projects include:
- Phenotypic handprints in patients with severe, treatment-resistant asthma: a systems biology and systems medicine approach (EU IMI)
- Breatheomics: pattern recognition of exhaled molecular biomarkers in the diagnosis, monitoring and management of respiratory disease
- Prognostic value of electronic nose assessment in pulmonary infections, acute lung injury and lung cancer
- The role of airway smooth muscle and its environment in the dynamics of airway narrowing.
- Induced exacerbations of asthma and COPD by experimental rhinovirus infection or allergens
- Segmental challenge with particulate matter in humans in vivo
- Gene expression profiling in upper and lower airways in patients with asthma and/or rhinitis
- The early determinants of long-term asthma outcome: airway inflammation, airway remodelling, and persistent virus infections
- Confirmed wheezing and molecular fingerprinting during infancy in the prediction of childhood asthma
- Prediction and prospective assessment of asthma exacerbations in the primary care setting
- Prospective assessment and therapy of COPD exacerbations

Theme: Infection and Immunit

This research group participates in CINIMA and CIA

Faculty
Prof. dr. P.J. Sterk

Postdocs
N. Fens MD PhD

PhD Students
M. Berger MD
P. Brinkman MEng
H. Coumou MD
C. Folisi
M.G. Gerritsen MD
L.E.S. de Groot
L. Guo
S. Hashimoto MD
Drs. P.W. Hekking
R.J.B. Loijmans MD
A. Ravi MSc
Drs. G.N. Rootmensen
Y.S. Sabogal Pineros MSc
T. Smulders BSc
P. van Velzen MD (Infectious Diseases (with prof JM Prins))
R. de Vries
Drs. K. de Heer MD
Drs. I. den Otter (Leiden University Medical Centre)
Drs. A.J. Ravensberg (Leiden University Medical Centre)

Others
P. Mau Asam

Other research related activities
  • Membership of editorial board / Editorship, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
  • Membership of editorial board / Editorship, RESPIRATORY RESEARCH
  • Membership of medical or scientific committee, ZonMw (Netherlands Organisation for Health Research and Development), Patient Participation
  • Membership of medical or scientific committee, Other, Chair of the board
  • Contribution to guidelines and protocols, ERS Guidelines on Exhaled Breath Assessments
Current research funding
  • Chiesi Pharmaceuticals B.V.
  • ERS Headquarters
  • Europese Unie
  • Longfonds
  • Universiteit Twente
  • University Hospital Antwerp
  • University of Southampton