• Male

Dr. G. Hamer PhD

Position: Scientific staff member (UD)
Main activities: Research
Specialisation: Reproductive Biology
foto
Focus of research:

Mammalian germ cell development and infertility.

 

AMC themes: Other research
Departments: Center for Reproductive Medicine
Jan SZ, Vormer TL, Jongejan A, Röling MD, Silber SJ, de Rooij DG, Hamer G, Repping S, van Pelt AMM, Unraveling transcriptome dynamics in human spermatogenesis. DEVELOPMENT 2017;144 (20):3659-3673 [PubMed]
Zheng Y, Jongejan A, Mulder CL, Mastenbroek S, Repping S, Wang Y, Li J, Hamer G, Trivial role for NSMCE2 during in vitro proliferation and differentiation of male germline stem cells. REPRODUCTION 2017;154 (3):181-195 [PubMed]
Cissen M, Wely Mv, Scholten I, Mansell S, Bruin JPd, Mol BW, Braat D, Repping S, Hamer G, Measuring Sperm DNA Fragmentation and Clinical Outcomes of Medically Assisted Reproduction: A Systematic Review and Meta-Analysis. PLOS ONE 2016;11 (11):e0165125 [PubMed]
Mulder CL, Zheng Y, Jan SZ, Struijk RB, Repping S, Hamer G, van Pelt AMM, Spermatogonial stem cell autotransplantation and germline genomic editing: a future cure for spermatogenic failure and prevention of transmission of genomic diseases. HUM REPROD UPDATE 2016;22 (5):561-573 [PubMed]
Verver DE, Hwang GH, Jordan PW, Hamer G, Resolving complex chromosome structures during meiosis: versatile deployment of Smc5/6. CHROMOSOMA 2016;125 (1):15-27 [PubMed]
Verver DE, Zheng Y, Speijer D, Hoebe R, Dekker HL, Repping S, Stap J, Hamer G, Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress. INT J MOL SCI 2016;17 (11):1782 [PubMed]
Hendriks S, Dancet EAF, van Pelt AMM, Hamer G, Repping S, Artificial gametes: a systematic review of biological progress towards clinical application. HUM REPROD UPDATE 2015;21 (3):285-296 [PubMed]
Hendriks S, Dondorp W, de Wert G, Hamer G, Repping S, Dancet EAF, Potential consequences of clinical application of artificial gametes: a systematic review of stakeholder views. HUM REPROD UPDATE 2015;21 (3):297-309 [PubMed]
Joustra SD, Meijer OC, Heinen CA, Mol IM, Laghmani EH, Sengers RMA, Carreno G, van Trotsenburg ASP, Biermasz NR, Bernard DJ, Wit JM, Oostdijk W, van Pelt AMM, Hamer G, Wagenaar GTM, Spatial and temporal expression of immunoglobulin superfamily member 1 in the rat. J ENDOCRINOL 2015;226 (3):181-191 [PubMed]
Verver DE. SMC5/6: Shaping, protecting and preparing the genome for safe reproduction. S.l.: s.n.; 2015. 123p. ISBN 978-94-6233-048-1 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Repping S; copromotor(s): Hamer G)
Verver DE, Langedijk NSM, Jordan PW, Repping S, Hamer G, The SMC5/6 complex is involved in crucial processes during human spermatogenesis. BIOL REPROD 2014;91 (1):22 [PubMed]
Verver DE, van Pelt AMM, Repping S, Hamer G, Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis. CELL DEATH DIS 2013;4:e749 [PubMed]
Jan SZ, Hamer G, Repping S, de Rooij DG, van Pelt AMM, Vormer TL, Molecular control of rodent spermatogenesis. BBA-MOL BASIS DIS 2012;1822 (12):1838-1850 [PubMed]
Hamer G, Matilainen O, Holmberg CI, A photoconvertible reporter of the ubiquitin-proteasome system in vivo. NAT METHODS 2010;7 (6):473-478 [PubMed]
Hamer G, Novak I, Kouznetsova A, Höög C, Disruption of pairing and synapsis of chromosomes causes stage-specific apoptosis of male meiotic cells. THERIOGENOLOGY 2008;69 (3):333-339 [PubMed]
Hamer G, Wang H, Bolcun-Filas E, Cooke HJ, Benavente R, Höög C, Progression of meiotic recombination requires structural maturation of the central element of the synaptonemal complex. J CELL SCI 2008;121 (Part 15):2445-2451 [PubMed]
Hamer G, Gell K, Kouznetsova A, Novak I, Benavente R, Höög C, Characterization of a novel meiosis-specific protein within the central element of the synaptonemal complex. J CELL SCI 2006;119 (Part 19):4025-4032 [PubMed]
Hamer G, Kal HB, Westphal CH, Ashley T, de Rooij DG, Ataxia telangiectasia mutated expression and activation in the testis. BIOL REPROD 2004;70 (4):1206-1212 [PubMed]
Hamer G, Roepers-Gajadien HL, Gademan IS, Kal HB, de Rooij DG, Intercellular bridges and apoptosis in clones of male germ cells. INT J ANDROL 2003;26 (6):348-353 [PubMed]
Hamer G, Roepers-Gajadien HL, van Duyn-Goedhart A, Gademan IS, Kal HB, van Buul PPW, Ashley T, de Rooij DG, Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86. BIOL REPROD 2003;68 (3):717-721 [PubMed]
Hamer G, Roepers-Gajadien HL, van Duyn-Goedhart A, Gademan IS, Kal HB, van Buul PPW, de Rooij DG, DNA double-strand breaks and gamma-H2AX signaling in the testis. BIOL REPROD 2003;68 (2):628-634 [PubMed]
Hamer G, Gademan IS, Kal HB, de rooij DG, Role for c-Abl and p73 in the radiation response of male germ cells. ONCOGENE 2001;20 (32):4298-4304 [PubMed]
Key publications

Mulder CL, Zheng Y, Jan SZ, Struijk RB, Repping S, Hamer G, van Pelt AMM, Spermatogonial stem cell autotransplantation and germline genomic editing: a future cure for spermatogenic failure and prevention of transmission of genomic diseases. HUM REPROD UPDATE 2016;22 (5):561-573 [PubMed]
Verver DE, Hwang GH, Jordan PW, Hamer G, Resolving complex chromosome structures during meiosis: versatile deployment of Smc5/6. CHROMOSOMA 2016;125 (1):15-27 [PubMed]
Verver DE, Langedijk NSM, Jordan PW, Repping S, Hamer G, The SMC5/6 complex is involved in crucial processes during human spermatogenesis. BIOL REPROD 2014;91 (1):22 [PubMed]
Verver DE, van Pelt AMM, Repping S, Hamer G, Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis. CELL DEATH DIS 2013;4:e749 [PubMed]
Hamer G, Matilainen O, Holmberg CI, A photoconvertible reporter of the ubiquitin-proteasome system in vivo. NAT METHODS 2010;7 (6):473-478 [PubMed]


All Publications

Research programmes

Prof. dr. F. van der Veen (Reproduction and development])

Prof. dr. S. Repping (Reproduction & Development -- Human Reproduction)

Other research related activities
  • None reported
Current research funding
  • AMC