• Male

Drs. M.C. van Aalderen MD

Position: PhD student
Main activities: Research
Specialisation: Virus-targeted immunity
foto
Focus of research:

The characterisation of the T-cell-mediated response against polyomavirus BK

AMC themes:
Departments: Experimental Immunology
van Aalderen MC, van den Biggelaar M, Remmerswaal EBM, van Alphen FPJ, Meijer AB, ten Berge IJM, van Lier RAW, Label-free Analysis of CD8(+) T Cell Subset Proteomes Supports a Progressive Differentiation Model of Human-Virus-Specific T Cells. CELL REP 2017;19 (5):1068-1079 [PubMed]
van Aalderen MC. The individuality of (virus-specific) CD8⁺ T cells. S.l.: s.n.; 2016. 266p. ISBN 978-94-6182-724-1 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): ten Berge RJM, van Lier RAW; copromotor(s): )
van Aalderen MC, Remmerswaal EBM, Heutinck KM, ten Brinke A, Feltkamp MCW, van der Weerd NC, van der Pant KAMI, Bemelman FJ, van Lier RAW, ten Berge IJM, Clinically Relevant Reactivation of Polyomavirus BK (BKPyV) in HLA-A02-Positive Renal Transplant Recipients Is Associated with Impaired Effector-Memory Differentiation of BKPyV-Specific CD8+ T Cells. PLOS PATHOG 2016;12 (10):e1005903 [PubMed]
Yapici Ü, Kers J, Slavujevic-Letic I, Stokman G, Roelofs JJTH, van Aalderen MC, Groothoff JW, de Boer OJ, van der Pant KAMI, Claessen N, Hilbrands LB, Bemelman FJ, ten Berge IJM, Florquin S, Intragraft Blood Dendritic Cell Antigen-1-Positive Myeloid Dendritic Cells Increase during BK Polyomavirus-Associated Nephropathy. J AM SOC NEPHROL 2016;27 (8):2502-2510 [PubMed]
van Aalderen MC, Remmerswaal EBM, Verstegen NJM, Hombrink P, ten Brinke A, Pircher H, Kootstra NA, ten Berge IJM, van Lier RAW, Infection history determines the differentiation state of human CD8+ T cells. J VIROL 2015;89 (9):5110-5123 [PubMed]
van Aalderen MC, Remmerswaal EBM, ten Berge IJM, van Lier RAW, Blood and beyond: properties of circulating and tissue-resident human virus-specific αβ CD8(+) T cells. EUR J IMMUNOL 2014;44 (4):934-944 [PubMed]
van Aalderen MC, Remmerswaal EBM, Heutinck KM, ten Brinke A, Pircher H, van Lier RAW, ten Berge IJM, Phenotypic and functional characterization of circulating polyomavirus BK VP1-specific CD8+ T cells in healthy adults. J VIROL 2013;87 (18):10263-10272 [PubMed]
van Aalderen MC, Yapici Ü, van der Pol JA, de Reijke TM, van Donselaar-van der Pant KAMI, Florquin S, Bemelman FJ, ten Berge IJM, Polyomavirus BK in the pathogenesis of bladder cancer. NETH J MED 2013;71 (1):26-28 [PubMed]
van Aalderen MC, Heutinck KM, Huisman C, ten Berge IJM, BK virus infection in transplant recipients: Clinical manifestations, treatment options and the immune response. NETH J MED 2012;70 (4):172-183 [PubMed]
Trappenburg MC, van Schilfgaarde M, Bredewold EO, van Aalderen MC, Spronk HMH, ten Cate H, Leyte A, Terpstra WE, Elevated numbers and altered subsets of procoagulant microparticles in breast cancer patients using endocrine therapy. THROMB RES 2011;127 (4):363-369 [PubMed]
van Aalderen MC, Trappenburg MC, van Schilfgaarde M, Molenaar PJ, ten Cate H, Terpstra WE, Leyte A, Procoagulant myeloblast-derived microparticles in AML patients: changes in numbers and thrombin generation potential during chemotherapy. J THROMB HAEMOST 2011;9 (1):223-226 [PubMed]
van Aalderen MC, Brinkman K, van den Berk GEL, Terpstra WE, Vinblastine, rituximab and HAART, treatment of an HIV -positive patient with multicentric Castleman's disease. NETH J MED 2010;68 (2):87-90 [PubMed]
Key publications



All Publications

Research programmes

Dr. F.J. Bemelman MD PhD (Improving renal transplantation)

Other research related activities
  • None reported
Current research funding
  • None reported