• Female

Dr. C.M.S. Ribeiro PhD

Position: Postdoc
Main activities: Research, Teaching
Specialisation: Immunology, Virology, Biochemistry
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Focus of research:

My research focuses on the function of autophagy pathway on dendritic cell subsets in innate immunity and infection in humans.  We are interested in the identification of host factors and receptor-mediated molecular mechanisms that govern autophagy induction during HIV-1 infection. Furthermore, we are investigating the role of autophagy in the induction of adaptive immunity in melanoma-derived tumors.

AMC themes: Infection & Immunity
Departments: Experimental Immunology
Gringhuis SI, Hertoghs N, Kaptein TM, Zijlstra-Willems EM, Sarrami-Fooroshani R, Sprokholt JK, van Teijlingen NH, Kootstra NA, Booiman T, van Dort KA, Ribeiro CMS, Drewniak A, Geijtenbeek TBH, HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3. NAT IMMUNOL 2017;18 (2):225-235 [PubMed]
Gringhuis SI, Hertoghs N, Kaptein TM, Zijlstra-Willems EM, Sarrami-Fooroshani R, Sprokholt JK, van Teijlingen NH, Kootstra NA, Booiman T, van Dort KA, Ribeiro CMS, Drewniak A, Geijtenbeek TBH, HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 (vol 18, pg 225, 2017). NAT IMMUNOL 2017;18 (4):474 [PubMed]
Hertoghs N, Geijtenbeek TBH, Ribeiro CMS, Interplay between HIV-1 innate sensing and restriction in mucosal dendritic cells: balancing defense and viral transmission. CURR OPIN VIROL 2017;22:112-119 [PubMed]
Ribeiro CMS, Sarrami-Forooshani R, Setiawan LC, Zijlstra-Willems EM, van Hamme JL, Tigchelaar W, van der Wel NN, Kootstra NA, Gringhuis SI, Geijtenbeek TBH, Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets. NATURE 2016;540 (7633):448-452 [PubMed]
Fink IR, Ribeiro CMS, Forlenza M, Taverne-Thiele A, Rombout JHWM, Savelkoul HFJ, Wiegertjes GF, Immune-relevant thrombocytes of common carp undergo parasite-induced nitric oxide-mediated apoptosis. DEV COMP IMMUNOL 2015;50 (2):146-154 [PubMed]
Ribeiro CMS, Sarrami-Forooshani R, Geijtenbeek TBH, HIV-1 border patrols: Langerhans cells control antiviral responses and viral transmission. FUTURE VIROL 2015;10 (11):1231-1243
Sarrami-Forooshani R, Mesman AW, van Teijlingen NH, Sprokholt JK, van der Vlist M, Ribeiro CMS, Geijtenbeek TBH, Human immature Langerhans cells restrict CXCR4-using HIV-1 transmission. RETROVIROLOGY 2014;11 (1):52 [PubMed]
van den Berg LM, Ribeiro CMS, Zijlstra-Willems EM, de Witte L, Fluitsma D, Tigchelaar W, Everts V, Geijtenbeek TBH, Caveolin-1 mediated uptake via langerin restricts HIV-1 infection in human Langerhans cells. RETROVIROLOGY 2014;11 (1):123 [PubMed]
van der Aa LM, Chadzinska M, Golbach LA, Ribeiro CMS, Lidy Verburg-van Kemenade BM, Pro-inflammatory functions of carp CXCL8-like and CXCb chemokines. DEV COMP IMMUNOL 2012;36 (4):741-750 [PubMed]
Ribeiro CMS, Bird S, Raes G, Ghassabeh GH, Schijns VEJC, Pontes MJSL, Savelkoul HFJ, Wiegertjes GF, A Novel Soluble Immune-Type Receptor (SITR) in Teleost Fish: Carp SITR Is Involved in the Nitric Oxide-Mediated Response to a Protozoan Parasite. PLOS ONE 2011;6 (1):e15986 [PubMed]
Ribeiro CMS, Hermsen T, Taverne-Thiele AJ, Savelkoul HFJ, Wiegertjes GF, Evolution of Recognition of Ligands from Gram-Positive Bacteria: Similarities and Differences in the TLR2-Mediated Response between Mammalian Vertebrates and Teleost Fish. J IMMUNOL 2010;184 (5):2355-2368 [PubMed]
Ribeiro CMS, Pontes MJSL, Bird S, Chadzinska M, Scheer M, Verburg-van Kemenade BML, Savelkoul HFJ, Wiegertjes GF, Trypanosomiasis-Induced Th17-Like Immune Responses in Carp. PLOS ONE 2010;5 (9):e13012 [PubMed]
Ribeiro CMS, Schijns VEJC, Immunology of vaccine adjuvants. METHODS MOL BIOL 2010;626:1-14 [PubMed]
Ruszczyk A, Forlenza M, Joerink M, Ribeiro CMS, Jurecka P, Wiegertjes GF, Trypanoplasma borreli cysteine proteinase activities support a conservation of function with respect to digestion of host proteins in common carp. DEV COMP IMMUNOL 2008;32 (11):1348-1361 [PubMed]
Joerink M, Forlenza M, Ribeiro CMS, de Vries BJ, Savelkoul HFJ, Wiegertjes GF, Differential macrophage polarisation during parasitic infections in common carp (Cyprinus carpio L.). FISH SHELLFISH IMMUN 2006;21 (5):561-571 [PubMed]
Joerink M, Ribeiro CMS, Stet RJM, Hermsen T, Savelkoul HFJ, Wiegertjes GF, Head kidney-derived macrophages of common carp (Cyprinus carpio L.) show plasticity and functional polarization upon differential stimulation. J IMMUNOL 2006;177 (1):61-69 [PubMed]
Key publications

van den Berg LM, Ribeiro CMS, Zijlstra-Willems EM, de Witte L, Fluitsma D, Tigchelaar W, Everts V, Geijtenbeek TBH, Caveolin-1 mediated uptake via langerin restricts HIV-1 infection in human Langerhans cells. RETROVIROLOGY 2014;11 (1):123 [PubMed]
Sarrami-Forooshani R, Mesman AW, van Teijlingen NH, Sprokholt JK, van der Vlist M, Ribeiro CMS, Geijtenbeek TBH, Human immature Langerhans cells restrict CXCR4-using HIV-1 transmission. RETROVIROLOGY 2014;11 (1):52 [PubMed]
Ribeiro CMS, Hermsen T, Taverne-Thiele AJ, Savelkoul HFJ, Wiegertjes GF, Evolution of Recognition of Ligands from Gram-Positive Bacteria: Similarities and Differences in the TLR2-Mediated Response between Mammalian Vertebrates and Teleost Fish. J IMMUNOL 2010;184 (5):2355-2368 [PubMed]
Ribeiro CMS, Pontes MJSL, Bird S, Chadzinska M, Scheer M, Verburg-van Kemenade BML, Savelkoul HFJ, Wiegertjes GF, Trypanosomiasis-Induced Th17-Like Immune Responses in Carp. PLOS ONE 2010;5 (9):e13012 [PubMed]
Joerink M, Ribeiro CMS, Stet RJM, Hermsen T, Savelkoul HFJ, Wiegertjes GF, Head kidney-derived macrophages of common carp (Cyprinus carpio L.) show plasticity and functional polarization upon differential stimulation. J IMMUNOL 2006;177 (1):61-69 [PubMed]


All Publications

Research programmes

Prof. dr. T.B.H. Geijtenbeek (Dendritic cells in infection and immunity)

Other research related activities
  • None reported
Current research funding
  • None reported