Dr. B.A. Heesters publications

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Publications Dr. B.A. Heesters

Position
Postdoc
Main activities
Research
Specialisation
Immunology, Complement, Stromal cells, B cells
Focus of research

Door tijdens meerdere rondes het beste antilichaam te selecteren kan het immuunsysteem steeds specifiekere antilichamen krijgen. Hierdoor werken sommige vaccins zo goed. Door het exacte mechanisme achter deze selectie te ontrafelen hoop ik te begrijpen waarom sommige vaccins beter werken dan anderen en met deze kennis vaccinaties te verbeteren.

Ik richt mij vooral op de interactie die B cellen hebben met Folliculaire Dendritische Cellen in de Germinal Center.

2016

  • Heesters BA, Carroll MC, The Role of Dendritic Cells in S. pneumoniae Transport to Follicular Dendritic Cells. CELL REP 2016;16 (12):3130-3137 [PubMed]
  • Heesters BA, van der Poel CE, Das A, Carroll MC, Antigen Presentation to B Cells. TRENDS IMMUNOL 2016;37 (12):844-854 [PubMed]

2015

  • Heesters BA, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC, Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes. PLOS PATHOG 2015;11 (12):e1005285 [PubMed]
  • Langereis MA, Bakkers MJG, Deng L, Padler-Karavani V, Vervoort SJ, Hulswit RJG, van Vliet ALW, Gerwig GJ, de Poot SAH, Boot W, van Ederen AM, Heesters BA, van der Loos CM, van Kuppeveld FJM, Yu H, Huizinga EG, Chen X, Varki A, Kamerling JP, de Groot RJ, Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins. CELL REP 2015;11 (12):1966-1978 [PubMed]
  • Mooster JL, Le Bras S, Massaad MJ, Jabara H, Yoon J, Galand C, Heesters BA, Burton OT, Mattoo H, Manis J, Geha RS, Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in I kappa B alpha. J EXP MED 2015;212 (2):185-202 [PubMed]

2014

  • Heesters BA, Das A, Chatterjee P, Carroll MC, Do follicular dendritic cells regulate lupus-specific B cells?. MOL IMMUNOL 2014;62 (2):283-288 [PubMed]
  • Heesters BA, Myers RC, Carroll MC, Follicular dendritic cells: dynamic antigen libraries. NAT REV IMMUNOL 2014;14 (7):495-504 [PubMed]
  • Woodruff MC, Heesters BA, Herndon CN, Groom JR, Thomas PG, Luster AD, Turley SJ, Carroll MC, Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine. J EXP MED 2014;211 (8):1611-1621 [PubMed]
  • Zhao F, Heesters BA, Chiu I, Gao Y, Shi J, Zhou N, Carroll MC, Xu B, L-Rhamnose-containing supramolecular nanofibrils as potential immunosuppressive materials. ORG BIOMOL CHEM 2014;12 (35):6816-6819 [PubMed]

2013

  • Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ, Bacteria activate sensory neurons that modulate pain and inflammation. NATURE 2013;501 (7465):52-+ [PubMed]
  • Heesters BA, Chatterjee P, Kim YA, Gonzalez SF, Kuligowski MP, Kirchhausen T, Carroll MC, Endocytosis and Recycling of Immune Complexes by Follicular Dendritic Cells Enhances B Cell Antigen Binding and Activation. IMMUNITY 2013;38 (6):1164-1175 [PubMed]
  • Woodruff MC, Herndon CN, Heesters BA, Carroll MC, Contextual Analysis of Immunological Response through Whole- Organ Fluorescent Imaging. LYMPHAT RES BIOL 2013;11 (3):121-127 [PubMed]

2012

  • Langereis MA, Zeng Q, Heesters BA, Heesters B, Huizinga EG, de Groot RJ, The Murine Coronavirus Hemagglutinin-esterase Receptor-binding Site: A Major Shift in Ligand Specificity through Modest Changes in Architecture. PLOS PATHOG 2012;8 (1):e1002492 [PubMed]

2011

  • Gonzalez SF, Degn SE, Pitcher LA, Woodruff M, Heesters BA, Carroll MC, Trafficking of B cell Antigen in Lymph Nodes. ANNU REV IMMUNOL 2011;29:215-233 [PubMed]