B.P. Scicluna BA MSc PhD

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BA MSc PhD B.P. Scicluna

Positions
Assistant Professor, Research Associate
Main activities
Research
Specialisation
Immunobiology and Genomics
Focus of research

Innate immunity; Pneumonia; Sepsis; Systems immunology; Epigenetics

Key publications
  • Scicluna Brendon P., Klein Klouwenberg Peter M. C., van Vught Lonneke A., Wiewel Maryse A., Ong David S. Y., Zwinderman Aeilko H., Franitza Marek, Toliat Mohammad R., Nürnberg Peter, Hoogendijk Arie J., Horn Janneke, Cremer Olaf L., Schultz Marcus J., Bonten Marc J., van der Poll Tom A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission American journal of respiratory and critical care medicine 2015;192 (7):826-835 [PubMed]
  • Cheng Shih-Chin, Scicluna Brendon P., Arts Rob J. W., Gresnigt Mark S., Lachmandas Ekta, Giamarellos-Bourboulis Evangelos J., Kox Matthijs, Manjeri Ganesh R., Wagenaars Jori A. L., Cremer Olaf L., Leentjens Jenneke, van der Meer Anne J., van de Veerdonk Frank L., Bonten Marc J., Schultz Marcus J., Willems Peter H. G. M., Pickkers Peter, Joosten Leo A. B., van der Poll Tom, Netea Mihai G. Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis Nature immunology 2016;17 (4):406-413 [PubMed]
  • van der Poll Tom, van de Veerdonk Frank L., Scicluna Brendon P., Netea Mihai G. The immunopathology of sepsis and potential therapeutic targets Nature reviews. Immunology 2017;17 (7):407-420 [PubMed]
  • Scicluna Brendon P., van Vught Lonneke A., Zwinderman Aeilko H., Wiewel Maryse A., Davenport Emma E., Burnham Katie L., Nürnberg Peter, Schultz Marcus J., Horn Janneke, Cremer Olaf L., Bonten Marc J., Hinds Charles J., Wong Hector R., Knight Julian C., van der Poll Tom, de Beer Friso M., Bos Lieuwe D. J., Frencken Jos F., Koster-Brouwer Maria E., van de Groep Kirsten, Verboom Diana M., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Hoogendijk Arie J., Huson Mischa A., Klouwenberg Peter M. Klein, Ong David S. Y., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study lancet. Respiratory medicine 2017;5 (10):816-826 [PubMed]
  • Scicluna Brendon P., Wiewel Maryse A., van Vught Lonneke A., Hoogendijk Arie J., Klarenbeek Augustijn M., Franitza Marek, Toliat Mohammad R., Nürnberg Peter, Horn Janneke, Bonten Marc J., Schultz Marcus J., Cremer Olaf L., van der Poll Tom A Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis Upon Intensive Care Unit Admission American journal of respiratory and critical care medicine 2018;197 (8):1070-1073 [PubMed]
All Publications
Curriculum Vitae

Education:

2006-2011 University of Amsterdam, Amsterdam, The Netherlands
PhD
Medicine
 Research thesis: “Systems-based approach for the identification of novel genes influencing cardiac electrical traits.”
Promotor: Prof. dr. Arthur A. M. Wilde MD PhD

2001-2003 University of Malta, Msida, Malta
MSc
Molecular Genetics
 Research thesis: “Proteomic detection of globin gene expression nuclear factors: Implementation of a HPLC-CE two-dimensional separation system.”
Promotor: Prof. A. E. Felice MD PhD

1997-2001 St. John’s University and College of St. Benedict, Minnesota, USA
Bachelors
Chemistry major
 Research thesis: “The molecular pathophysiology of Duchenne’s Muscular Dystrophy – A molecular genetics approach”
Promotor: Abbot Prof. John Klassen OSB PhD
 

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