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Dr. E.M.M. van Leeuwen

Position
Scientific staff member (UD)
Main activities
Patient care, Research
Specialisation
Medical Immunology, Human anti-viral T cell responses, Immunodeficiencies
Focus of research

T cell responses in human viral infections

Immunodeficiency

Key publications
  • Aan de Kerk DJ, Jansen MH, ten Berge IJM, van Leeuwen EMM, Kuijpers TW, Identification of B cell defects using age-defined reference ranges for in vivo and in vitro B cell differentiation. J IMMUNOL 2013;190 (10):5012-5019 [PubMed]
  • de Niet A, de Bruijne J, Plat-Sinnige MJT, Takkenberg RB, van Lier RAW, Reesink HW, van Leeuwen EMM, Upregulation of CXCR3 expression on CD8+ T cells due to the pervasive influence of chronic hepatitis B and C virus infection. HUM IMMUNOL 2013;74 (8):899-906 [PubMed]
  • Létourneau S, van Leeuwen EMM, Krieg C, Martin C, Pantaleo G, Sprent J, Surh CD, Boyman O, IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25. P NATL ACAD SCI USA 2010;107 (5):2171-2176 [PubMed]
  • van Leeuwen EMM, Sprent J, Surh CD, Generation and maintenance of memory CD4(+) T Cells. CURR OPIN IMMUNOL 2009;21 (2):167-172 [PubMed]
  • Kuijpers TW, van Leeuwen EMM, Barendregt BH, Klarenbeek P, Aan de Kerk DJ, Baars PA, Jansen MH, de Vries N, van Lier RAW, van der Burg M, A reversion of an IL2RG mutation in combined immunodeficiency providing competitive advantage to the majority of CD8+ T cells. HAEMATOLOGICA 2013;98 (7):1030-1038 [PubMed]
All Publications
Research programmes

Prof. dr. T.B.H. Geijtenbeek (Dendritic cells in infection and immunity)