Dr. F. Holleman MD PhD

Associate professor (UHD)
Main activities
Research, Patient care, Teaching
Diabetes research; acute internal medicine
Focus of research

Clinical treatment and complications of diabetes mellitus.

Clinical treatment focus: 1. insulin analogs and insulin therapy 2. Ethnicity 3. Hypoglycemia

Complications: 1. disturbance of glycocalyx and coagulation  2. gut flora and metabolism

Key publications
  • Swinnen SG, Dain MP, Aronson R, Davies M, Gerstein HC, Pfeiffer AF, Snoek FJ, DeVries JH, Hoekstra JB, Holleman F, A 24-Week, Randomized, Treat-to-Target Trial Comparing Initiation of Insulin Glargine Once-Daily With Insulin Detemir Twice-Daily in Patients With Type 2 Diabetes Inadequately Controlled on Oral Glucose-Lowering Drugs. DIABETES CARE 2010;33 (6):1176-1178 [PubMed]
  • Siegelaar SE, Holleman F, Hoekstra JBL, DeVries JH, Glucose Variability; Does It Matter?. ENDOCR REV 2010;31 (2):171-182 [PubMed]
  • Vrieze A, Holleman F, Zoetendal EG, de Vos WM, Hoekstra JBL, Nieuwdorp M, The environment within: how gut microbiota may influence metabolism and body composition. DIABETOLOGIA 2010;53 (4):606-613 [PubMed]
  • Holleman F, Vermeijden JW, Kuck EM, Hoekstra JB, Erkelens DW, Compatibility of insulin pens and cartridges. LANCET 1997;350 (9091):1601-1602 [PubMed]
  • Holleman F, Hoekstra JB, Insulin lispro. NEW ENGL J MED 1997;337 (3):176-183 [PubMed]
All Publications
Other research related activities
  • Membership of medical or scientific committee, Diabetesfonds, Scientific Advisory Board
  • Board of directors / Trustees / Supervisory board, Nederlandse Vereniging voor DiabetesOnderzoek