foto

Dr. G. Stokman

Position
Postdoc
Main activities
Research
Specialisation
Tubular epithelial cell injury and repair.
Focus of research

Role of Exchange Protein directly Activated by cAMP (Epac) in tubular damage and nephrotoxicity.

Toll-like receptors drive tubular repair by regulating Wnt expression and epithelial morphogenesis.


 

 

Key publications
  • Stokman G, Qin Y, Genieser HG, Schwede F, de Heer E, Bos JL, Bajema IM, van de Water B, Price LS, Epac-Rap signaling reduces cellular stress and ischemia-induced kidney failure. J AM SOC NEPHROL 2011;22 (5):859-872 [PubMed]
  • Stokman G, Qin Y, Rácz Z, Hamar P, Price LS, Application of siRNA in targeting protein expression in kidney disease. ADV DRUG DELIVER REV 2010;62 (14):1378-1389 [PubMed]
  • Stokman G, Leemans JC, Claessen N, Weening JJ, Florquin S, Hematopoietic stem cell mobilization therapy accelerates recovery of renal function independent of stem cell contribution. J AM SOC NEPHROL 2005;16 (6):1684-1692 [PubMed]
  • Leemans JC, Stokman G, Claessen N, Rouschop KM, Teske GJD, Kirschning CJ, Akira S, van der Poll T, Weening JJ, Florquin S, Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J CLIN INVEST 2005;115 (10):2894-2903 [PubMed]
  • Stokman G, Qin Y, Booij TH, Ramaiahgari S, Lacombe M, Dolman MEM, van Dorenmalen KMA, Teske GJD, Florquin S, Schwede F, van de Water B, Kok RJ, Price LS, Epac-Rap signaling reduces oxidative stress in the tubular epithelium. J AM SOC NEPHROL 2014;25 (7):1474-1485 [PubMed]
All Publications
Research programmes

Prof. dr. S. Florquin (Renal inflammation and repair)