Dr. G.J.W. van der Windt

Main activities
Focus of research

Investigating the impact of cellular metabolism on immune cell function during infections and cancer.

Key publications
  • van der Windt GJW, Everts B, Chang CH, Curtis JD, Freitas TC, Amiel E, Pearce EJ, Pearce EL, Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8(+) T Cell Memory Development. IMMUNITY 2012;36 (1):68-78 [PubMed]
  • van der Windt GJW, Pearce EL, Metabolic switching and fuel choice during T-cell differentiation and memory development. IMMUNOL REV 2012;249 (1):27-42 [PubMed]
  • van der Windt GJW, O'Sullivan D, Everts B, Huang SCC, Buck MD, Curtis JD, Chang CH, Smith AM, Ai T, Faubert B, Jones RG, Pearce EJ, Pearce EL, CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability. P NATL ACAD SCI USA 2013;110 (35):14336-14341 [PubMed]
  • van der Windt GJW, Chang CH, Pearce EL, Measuring Bioenergetics in T Cells Using a Seahorse Extracellular Flux Analyzer. CURR PROTOC IMMUNOL 2016;113:3.16B.1-3.16B.14 [PubMed]
  • Siska PJ, van der Windt GJW, Kishton RJ, Cohen S, Eisner W, MacIver NJ, Kater AP, Weinberg JB, Rathmell JC, Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia. J IMMUNOL 2016;197 (6):2532-2540 [PubMed]
All Publications
Research programmes

Prof. dr. E. Eldering (Apoptosis regulation in immuno-hematology)

Prof. dr. A.P. Kater MD PhD (development of, circumvention of and novel strategies for (development of) chemorefractory CLL)