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Dr. J. Aten

Position
Scientific staff member (UD)
Main activities
Research, Teaching
Specialisation
pathology, immunology
Focus of research
  • Pathobiology of the glomerular visceral epithelial cell in development of nephrotic syndrome.
  • Pathogenesis of renal fibrosis.
Key publications
  • Marques ARA, Aten J, Ottenhoff R, van Roomen CPAA, Herrera Moro D, Claessen N, Vinueza Veloz MF, Zhou K, Lin Z, Mirzaian M, Boot RG, de Zeeuw CI, Overkleeft HS, Yildiz Y, Aerts JMFG, Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice. PLOS ONE 2015;10 (8):e0135889 [PubMed]
  • Sachs N, Claessen N, Aten J, Kreft M, Teske GJD, Koeman A, Zuurbier CJ, Janssen H, Sonnenberg A, Blood pressure influences end-stage renal disease of Cd151 knockout mice. J CLIN INVEST 2012;122 (1):348-358 [PubMed]
  • Reuwer A, van Eijk M, Houttuijn-Bloemendaal F, van der Loos C, Claessen N, Teeling P, Kastelein JJ, Hamann J, Goffin V, von der Thüsen J, Twickler M, Aten J, The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis?. J ENDOCRINOL 2011;208 (2):107-117 [PubMed]
  • Ito Y, Goldschmeding R, Kasuga H, Claessen N, Nakayama M, Yuzawa Y, Sawai A, Matsuo S, Weening JJ, Aten J, Expression patterns of connective tissue growth factor and of TGF-beta isoforms during glomerular injury recapitulate glomerulogenesis. AM J PHYSIOL-RENAL 2010;299 (3):F545-F558 [PubMed]
  • Witte MD, Kallemeijn WW, Aten J, Li KY, Strijland A, Donker-Koopman WE, van den Nieuwendijk AMCH, Bleijlevens B, Kramer G, Florea BI, Hooibrink B, Hollak CEM, Ottenhoff R, Boot RG, van der Marel GA, Overkleeft HS, Aerts JMFG, Ultrasensitive in situ visualization of active glucocerebrosidase molecules. NAT CHEM BIOL 2010;6 (12):907-913 [PubMed]
All Publications
Research programmes

Prof. dr. S. Florquin (Renal inflammation and repair)