Dr. L. van Dussen

Main activities
Focus of research

m. Gaucher

Key publications
  • van Dussen L, Lips P, Everts VE, Bravenboer N, Jansen IDC, Groener JEM, Maas M, Blokland JAK, Aerts JMFG, Hollak CEM, Markers of bone turnover in Gaucher disease: modeling the evolution of bone disease. J CLIN ENDOCR METAB 2011;96 (7):2194-2205 [PubMed]
  • van Dussen L, Biegstraaten M, Hollak CEM, Dijkgraaf MGW, Cost-effectiveness of enzyme replacement therapy for type 1 Gaucher disease. ORPHANET J RARE DIS 2014;9 (1):51 [PubMed]
  • van Dussen L, Biegstraaten M, Dijkgraaf MG, Hollak CE, Modelling Gaucher disease progression: long-term enzyme replacement therapy reduces the incidence of splenectomy and bone complications. ORPHANET J RARE DIS 2014;9 (1):112 [PubMed]
  • van Dussen L, Hendriks EJ, Groener JEM, Boot RG, Hollak CEM, Aerts JMFG, Value of plasma chitotriosidase to assess non-neuronopathic Gaucher disease severity and progression in the era of enzyme replacement therapy. J INHERIT METAB DIS 2014;37 (6):991-1001 [PubMed]
  • van Dussen L, Akkerman EM, Hollak CEM, Nederveen AJ, Maas M, Evaluation of an imaging biomarker, Dixon quantitative chemical shift imaging, in Gaucher disease: lessons learned. J INHERIT METAB DIS 2014;37 (6):1003-1011 [PubMed]
All Publications
Research programmes

Prof. dr. C.E.M. Hollak (Natural history, pathophysiology and treatment of lysosomal storage disorders and regulatory science of orphan drugs)