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Dr. M.E. Doorenspleet MSc

Position
PhD student
Main activities
Research
Specialisation
B-cell receptor repertoires in (auto)immunity
Focus of research

B-cell receptor repertoires in (auto)immunity

The genetics of rheumatoid arthritis

Key publications
  • Doorenspleet ME , Klarenbeek PL, de Hair MJH, van Schaik BDC, Esveldt REE, van Kampen AHC, Gerlag DM, Musters A, Baas F, Tak PP, de Vries N, Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity. ANN RHEUM DIS 2014;73 (4):756-762 [PubMed]
  • Maillette de Buy Wenniger LJ, Doorenspleet ME, Klarenbeek PL, Verheij J, Baas F, Elferink RPO, Tak PP, de Vries N, Beuers U, Immunoglobulin G4+ clones identified by next-generation sequencing dominate the B cell receptor repertoire in immunoglobulin G4 associated cholangitis. HEPATOLOGY 2013;57 (6):2390-2398 [PubMed]
  • Cantaert T, Doorenspleet ME, Francosalinas G, Paramarta JE, Klarenbeek PL, Tiersma Y, van der Loos CM, de Vries N, Tak PP, Baeten DL, Increased numbers of CD5+ B lymphocytes with a regulatory phenotype in spondylarthritis. ARTHRITIS RHEUM-US 2012;64 (6):1859-1868 [PubMed]
All Publications
Research programmes

Prof. dr. N. de Vries MD PhD (“Adaptive immunomics”: Immunogenomic approaches to selectively monitor and target adaptive immune responses in immune-mediated inflammatory disease)