Dr. R.J.T. Mocking MD MSc PhD

Main activities
Patient care, Research, Teaching
Biological psychiatry
Focus of research

As a Postdoc I have a broad interest in applying research to personalise psychiatry and provide an evidence base for daily clinical practice.

My PhD focused on endocrinological and metabolic alterations in depression. By applying interdisciplinary and multimodal methods we linked fatty acids to HPA-axis functioning and neuroimaging. Findings, including our meta-analyses, suggest that dietary omega-3 fatty acids can improve antidepressant effectivity. This was implemented in the Dutch guidelines and the diet served at the department of psychiatry of the AMC now includes more omega-3 fatty acids. 

During my Postdoc I am involved in research on deep brain stimulation for psychiatric disorders in the Denys group. In addition I perform a literature study on physical and pharmacological restraints in hospital care.

For more information, see:, or

Key publications
  • ter Horst DM, Schene AH, Figueroa CA, Assies J , Lok A , Bockting CLH, Ruhé HG, Mocking RJT, Cortisol, dehydroepiandrosterone sulfate, fatty acids, and their relation in recurrent depression. PSYCHONEUROENDOCRINO 2018;100:203-212 [PubMed]
  • Mocking RJT , Nap TS, Westerink AM, Assies J , Vaz FM, Koeter MWJ, Ruhé HG, Schene AH, Biological profiling of prospective antidepressant response in major depressive disorder: Associations with (neuro)inflammation, fatty acid metabolism, and amygdala-reactivity. PSYCHONEUROENDOCRINO 2017;79:84-92 [PubMed]
  • Mocking RJT , Harmsen I, Assies J , Koeter MWJ, Ruhé HG, Schene AH, Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder. TRANSL PSYCHIAT 2016;6:e756 [PubMed]
  • Rive MM, Mocking RJT, Koeter MWJ, van Wingen G, de Wit SJ, van den Heuvel OA, Veltman DJ, Ruhé HG , Schene AH, State-Dependent Differences in Emotion Regulation Between Unmedicated Bipolar Disorder and Major Depressive Disorder. JAMA PSYCHIAT 2015;72 (7):687-696 [PubMed]
  • Assies J, Mocking RJT, Pouwer F, Maternal depression and child development after prenatal DHA supplementation. JAMA-J AM MED ASSOC 2011;305 (4):360; author reply 360-360; author reply 361 [PubMed]
All Publications
Curriculum Vitae

Available on request

Other research related activities
  • Membership of medical or scientific committee, Nederlandse Vereniging voor Psychiatrie, Commissie Wetenschappelijke Activiteiten
  • Membership of advisory board / Consultant, GR (GezondheidsRaad, Dutch Health Council)
  • Redactielid, De Jonge Psychiater