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Dr. S.M. Hermans MSc PhD

Position
Scientific staff member (UD)
Main activities
Research, Patient care
Specialisation
Infectious Diseases Epidemiology
Focus of research

My research interests include the epidemiology of HIV and tuberculosis co-infection, in particular recurrent tuberculosis, and operational research into the implementation of optimal strategies of health care delivery in sub-Saharan Africa.

My current research projects include epidemiological analyses of a decade of data on tuberculosis in the City of Cape Town, South Africa, and Kampala, Uganda. My particular interest is to determine the burden of recurrent TB using deterministic linkage techniques. I also investigate the impact of public health interventions such as antiretroviral therapy and Xpert MTB/RIF on population level TB notification rates. I am the principal investigator of a TB case finding study in rural Tanzania funded by TB Reach (WHO Stop TB department), and am the lead clinical investigator on a universal HIV test & treat programme in the same area.

I am involved in the mentorship of students at various levels: bachelorthesis BSc Medicine (AMC) and the Global Health Elective course (VUMc). I am the co-supervisor of two PhD students undertaking research into TB epidemiology in South Africa and Mozambique.

Key publications
  • Hermans SM, Grant AD, Chihota V, Lewis JJ, Vynnycky E, Churchyard GJ, Fielding KL, The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study. BMC MED 2016;14 (1):45 [PubMed]
  • Hermans S, Horsburgh CR Jr, Wood R, A Century of Tuberculosis Epidemiology in the Northern and Southern Hemisphere: The Differential Impact of Control Interventions. PLOS ONE 2015;10 (8):e0135179 [PubMed]
  • Hermans S, Manabe Y, Population-level tuberculosis incidence in the ART era. LANCET INFECT DIS 2015;15 (9):997-998 [PubMed]
  • Hermans S, Boulle A, Caldwell J, Pienaar D, Wood R, Temporal trends in TB notification rates during ART scale-up in Cape Town: an ecological analysis. J INT AIDS SOC 2015;18 (1):20240 [PubMed]
  • Hermans SM, Castelnuovo B, Katabira C, Mbidde P, Lange JMA, Hoepelman AIM, Coutinho A, Manabe YC, Integration of HIV and TB Services Results in Improved TB Treatment Outcomes and Earlier Prioritized ART Initiation in a Large Urban HIV Clinic in Uganda. JAIDS-J ACQ IMM DEF 2012;60 (2):E29-E35 [PubMed]
All Publications
Curriculum Vitae

Sabine Hermans is an assistant professor at the Amsterdam Institute for Global Health and Development (AIGHD) and the Department of Global Health, University of Amsterdam. She also works as a clinician at the Department of Tropical Medicine at the AMC.

Sabine trained as an internist and infectious diseases specialist in the Netherlands. From 2008 to 2012 she was based at the Infectious Diseases Institute (IDI), part of Makerere University College of Health Sciences in Kampala, Uganda, seconded by the University of Utrecht and later AIGHD. She set up and headed the integrated TB/HIV clinic at the IDI, which she combined with research leading toward the completion of her PhD at the University of Utrecht in June 2012 (under joint supervision of late Prof. Joep Lange and Prof. Andy Hoepelman). She subsequently moved to the London School of Hygiene and Tropical Medicine, where she obtained her MSc in Epidemiology in 2013 (with distinction).

A 3 year Marie Curie post-doctoral fellowship granted by the European Commission allowed Sabine to join the Desmond Tutu HIV Centre at the University of Cape Town, seconded by AIGHD, from October 2013 to March 2016. There she worked on epidemiological analyses of a decade of data on tuberculosis in the City of Cape Town and helped develop a mathematical model of TB in the city. She also worked as a clinician at the Hannan Crusaid Antiretroviral Treatment Centre in Gugulethu, Cape Town.

Her research has focused on the epidemiology of HIV and TB co-infection and operational research into health care delivery strategies. She has also undertaken historical and cost-effectiveness research in this field. In the past she led a prospective non-randomised interventional study of the effect of a Short Message Service (SMS) reminder service on improving TB treatment completion in Uganda. In 2011 she was awarded the annual International AIDS Society TB-HIV research prize for her operational research on antiretroviral treatment initiation at the IDI integrated TB-HIV clinic.

 


 

Research programmes

Prof. dr. F.G.J. Cobelens MD MSc PhD (Epidemiology and control of poverty-related infectious diseases)

Prof. dr. T.F. Rinke de Wit PhD (Multi-disciplinary public health research in Africa)