Drs. A.H. van der Spek

PhD student
Main activities
Focus of research

 The role of thyroid hormone metabolism in the function of innate immune cells

Key publications
  • van der Spek AH, Bloise FF, Tigchelaar W, Dentice M, Salvatore D, van der Wel NN, Fliers E, Boelen A, The Thyroid Hormone Inactivating Enzyme Type 3 Deiodinase is Present in Bactericidal Granules and the Cytoplasm of Human Neutrophils. ENDOCRINOLOGY 2016;157 (8):3293-3305 [PubMed]
  • van der Spek AH, Fliers E, Boelen A, Thyroid hormone metabolism in innate immune cells. J ENDOCRINOL 2017;232 (2):R67-R81 [PubMed]
  • van der Spek AH, Fliers E, Boelen A, The classic pathways of thyroid hormone metabolism. MOL CELL ENDOCRINOL 2017;458 (C):29-38 [PubMed]
  • Boelen A, van der Spek AH, Bloise F, de Vries EM, Surovtseva OV, van Beeren M, Ackermans MT, Kwakkel J, Fliers E, Tissue thyroid hormone metabolism is differentially regulated during illness in mice. J ENDOCRINOL 2017;233 (1):25-36 [PubMed]
  • Bloise FF, van der Spek AH, Surovtseva OV, Ortiga-Carvalho TM, Fliers E, Boelen A, Differential Effects of Sepsis and Chronic Inflammation on Diaphragm Muscle Fiber Type, Thyroid Hormone Metabolism, and Mitochondrial Function. THYROID 2016;26 (4):600-609 [PubMed]
All Publications