MD PhD G. van Tienhoven

Medical Specialist
Main activities
Patient care, Research
Radiation Oncology
Focus of research

Pancreatic cancer, with a focus on multidisciplinary collaboration in clinical research and translational research.

Board member, co founder and member scientific committee of the Dutch Pancreatic Cancer Group (DPCG), a multidisciplinary research group on pancreatic cancer since 2012

- PI of the National PREOPANC phase 3 trial comparing upfront surgery with neo adjuvant radiochemotherapy (finished accrual july 2017; Final analysis in press) 

       Co PI of KWF project to investigate motion of pancreatic tumours treated with radiation ( UVA 2011-5017; co promotor E. Lens June 2, 2017)

- PI of the PAINPANC single arm phase 2 study, on pain palliation by short term radiation (3 X 8 Gy); (finished accrual, analysis in progress)                                                                                                                                                                                                                                                                                                                                                                     

- co PI of the PREOPANC-2 phase 3 trial, Comparing the best arm of PREOPANC-1 to neo adjuvant 8 courses of FOLFIRINOX chemotherapy (running) the

- co PI of the PANCOSAR trial, Cohort Multiple Controlled Randomized Trial (Phase 2) to investigate the role of stereotactic radiation in Locally advanced or recurrent pancreatic cancer (in preparation, National) 

- co PI of the FIBROPANC trial, Single arm feasibility trial to investigate whether a single fraction of radiation can prevent postoperative fistula in patiënts undergoing a pancreaticoduodenectomy. (in preparation, National).  

- co PI of KWF grant application:  Reduction of organ motion during radiotherapy by non-invasive mechanical ventilation supported breathing control.

Key publications
  • Bolla Michel, van Poppel Hein, Tombal Bertrand, Vekemans Kris, Da Pozzo Luigi, de Reijke Theo M., Verbaeys Antony, Bosset Jean-François, van Velthoven Roland, Colombel Marc, van de Beek Cees, Verhagen Paul, van den Bergh Alphonsus, Sternberg Cora, Gasser Thomas, van Tienhoven Geertjan, Scalliet Pierre, Haustermans Karin, Collette Laurence Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911) Lancet 2012;380 (9858):2018-2027 [PubMed]
  • van Laethem Jean-Luc, Hammel Pascal, Mornex Françoise, Azria David, van Tienhoven Geertjan, Vergauwe Philippe, Peeters Marc, Polus Marc, Praet Michel, Mauer Murielle, Collette Laurence, Budach Volker, Lutz Manfred, van Cutsem Eric, Haustermans Karin Adjuvant Gemcitabine Alone Versus Gemcitabine-Based Chemoradiotherapy After Curative Resection for Pancreatic Cancer: A Randomized EORTC-40013-22012/FFCD-9203/GERCOR Phase II Study Journal of clinical oncology 2010;28 (29):4450-4456 [PubMed]
  • Straver Marieke E., Meijnen Philip, van Tienhoven Geertjan, van de Velde Cornelis J. H., Mansel Robert E., Bogaerts Jan, Demonty Gaston, Duez Nicole, Cataliotti Luigi, Klinkenbijl Jean, Westenberg Helen A., van der Mijle Huub, Hurkmans Coen, Rutgers Emiel J. T. Role of Axillary Clearance After a Tumor-Positive Sentinel Node in the Administration of Adjuvant Therapy in Early Breast Cancer Journal of clinical oncology 2010;28 (5):731-737 [PubMed]
  • Bolla Michel, de Reijke Theodorus M., van Tienhoven Geertjan, van den Bergh Alphonsus C. M., Oddens Jorg, Poortmans Philip M. P., Gez Eliahu, Kil Paul, Akdas Atif, Soete Guy, Kariakine Oleg, van der Steen-Banasik Elsbietha M., Musat Elena, Piérart Marianne, Mauer Murielle E., Collette Laurence, van den Bergh A. C. M., Oddens J., Poortmans P. M. P., Kil P., van Andel G., van der Steen-Banasik E. M., van de Beek C., Schimmel E., Bolla M., Descotes J. L., Bosset J.-F., Hay M. H., Bachaud J.-M., Maingon P., Courdi A., Barillot I., Carrie C., Rothe-Thomas F., Gez E., Akdas A., Lekili M., Soete G., van Poppel H., Vekemans K., van Houtte P., Verbaeys A., Hoekx L., Kariakine O., Cutajar C. L., Mirimanoff R., Magrini S. M., Busetto M., Bono A., Villa S. Duration of androgen suppression in the treatment of prostate cancer New England journal of medicine 2009;360 (24):2516-2527 [PubMed]
  • Klerk Clara P. W., Smorenburg Susanne M., Otten Hans-Martin, Lensing Anthonie W. A., Prins Martin H., Piovella Franco, Prandoni Paolo, Bos Monique M. E. M., Richel Dick J., van Tienhoven Geertjan, Büller Harry R. The effect of low molecular weight heparin on survival in patients with advanced malignancy Journal of clinical oncology 2005;23 (10):2130-2135 [PubMed]
All Publications
Curriculum Vitae

Training: 1991: registration radiation oncologist
1997: Thesis Ph.D., University of Amsterdam; 
Employment: 1991-ongoing: radiation oncologist, AMC, dept of radiation oncology and Hyperthermia

Membership of a number of regional, national and international organisations, among which:

CKTO (Committee for Clinical Comparative Research) from the Dutch Cancer Society KWF; 1999 - 2005



mittee for Clinical Comparative Research) from the Dutch Cancer Society KWF; 1999 – 2005. European Organisation of Research in Treatment of Cancer (EORTC). Currently in the steering committees of the Radiation Oncology Group (ROG) and the Breast Cancer Group (BCG), in the General Assembly and institute representative for the Network of Core Institutions (NOCI).

Board member National Society of Radiation Oncology (NVRO) 2001-2007 Scientific committee of National Society of Radiation Oncology (NVRO) since 2001-2009, Chairman 2004-2009

Involved in the organisation of conferences: European Breast Cancer Conferences IV-VII, Breast Cancer from Gene to Cure 2006 and the Dutch National Multidisciplinary Conference “Therapie op Maat”(means Taylor made Therapy) I, II and III (currently chair). Member faculty IAEA course Evidence based Radiotherapy for Breast Cancer, Istanbul,Istanbul, May 23-27, 2009

Research programmes

MD PhD G. van Tienhoven (Promoties)

PhD Students
MD M.W. Kolff
MSc S. Oldenborg

Prof. PhD C.R.N. Rasch (Image guided and physics application in the clinic)