H.J. Verberne PhD

Medical Specialist
Main activities
Education, Patient care, Research, Other
Nuclear cardiology with emphasis on myocardial sympathetic activity
Focus of research

The focus is on the application of nuclear medicine techniques to cardiovascular diseases:

  1. Studying the role of myocardial symphathetic activity in heart failure patients with 123I-MIBG. In this context a European network has been constructed to obtain relevant data.
  2. In collaboration with the group of Prof dr ES Stroes looking at inflamation of the vascular wall and the effects of farmacological interventions with 18F-FDG and labelled leucocytes.
  3. In collaboration with Prof dr JJ Piek studying new tracers for the imaging of neovascularization in patients with chronic coronary artery occlusions.
  4. In collaboration with F Holleman studying brown adipose tissue and ways to selectively stimulate/activate brown adipose tissue.
Key publications
  • Campian Maria E., Verberne Hein J., Hardziyenka Maxim, de Bruin Kora, Selwaness Mariana, van den Hoff Maurice J. B., Ruijter Jan M., van Eck-Smit Berthe L. F., de Bakker Jacques M. T., Tan Hanno L. Serial Noninvasive Assessment of Apoptosis During Right Ventricular Disease Progression in Rats Journal of nuclear medicine 2009;50 (8):1371-1377 [PubMed]
  • Agostini Denis, Verberne Hein J., Burchert Wolfgang, Knuuti Juhani, Povinec Pavol, Sambuceti Gianmario, Unlu Mustafa, Estorch Montserrat, Banerjee Gopa, Jacobson Arnold F. I-123-mIBG myocardial imaging for assessment of risk for a major cardiac event in heart failure patients: insights from a retrospective European multicenter study European journal of nuclear medicine and molecular imaging 2008;35 (3):535-546 [PubMed]
  • Verberne Hein J., Brewster Lizzy M., Somsen G. Aernout, van Eck-Smit Berthe L. F. Prognostic value of myocardial 123I-metaiodobenzylguanidine (MIBG) parameters in patients with heart failure: a systematic review European heart journal 2008;29 (9):1147-1159 [PubMed]
  • Erol-Yilmaz Ayten, Verberne Hein J., Schrama Tim A., Hrudova Jana, de Winter Robbert J., van Eck-Smit Berthe L. F., de Bruin Rianne, Bax Jeroen J., Schalij Martin J., Wilde Arthur A., Tukkie Raymond Cardiac resynchronization induces favorable neurohumoral changes Pacing and clinical electrophysiology 2005;28 (4):304-310 [PubMed]
  • van der Zee P. Marc, Verberne Hein J., van Straalen Jan P., Sanders Gerard T. B., van Eck-Smit Berthe L. F., de Winter Robbert J., Fischer Johan C. Ischemia-modified albumin measurements in symptom-limited exercise myocardial perfusion scintigraphy reflect serum albumin concentrations but not myocardial ischemia Clinical chemistry 2005;51 (9):1744-1746 [PubMed]
All Publications
Research programmes

H.J. Verberne PhD (Promoties)

Prof. B.L.F. van Eck-Smit PhD (Molecular imaging from mice to men)

Current research funding
  • Siemens Healthcare Nederland B.V.