foto

BEng H.M. Rodermond

Position
Support Staff
Main activities
Research, Other
Specialisation
Radiation research in vitro & in vivo
Focus of research

DNA repair after radiation ; hyperthermia ; chemotherapy and combinations

Key publications
  • Krawczyk Przemek M., Eppink Berina, Essers Jeroen, Stap Jan, Rodermond Hans, Odijk Hanny, Zelensky Alex, van Bree Chris, Stalpers Lukas J., Buist Marrije R., Soullié Thomas, Rens Joost, Verhagen Hence J. M., O'Connor Mark J., Franken Nicolaas A. P., ten Hagen Timo L. M., Kanaar Roland, Aten Jacob A. Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition Proceedings of the National Academy of Sciences of the United States of America 2011;108 (24):9851-9856 [PubMed]
  • van Bree C., Rodermond H. M., Leen R., Medema J. P., van Kuilenburg A. B. P. Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells British journal of cancer 2008;98 (7):1226-1233 [PubMed]
  • van Bree Chris, Rodermond Hans M., ten Cate Rosemarie, de Vos Judith, Stalpers Lukas J. A., Haveman Jaap, Medema Jan Paul, Franken Nicolaas A. P. G0 cell cycle arrest alone is insufficient for enabling the repair of ionizing radiation-induced potentially lethal damage Radiation research 2008;170 (2):184-191 [PubMed]
  • Franken Nicolaas A. P., Rodermond Hans M., Stap Jan, Haveman Jaap, van Bree Chris Clonogenic assay of cells in vitro Nature protocols 2006;1 (5):2315-2319 [PubMed]
  • van Bree Chris, Rodermond Hans M., de Vos Judith, Haveman Jaap, Franken Nicolaas A. P. Mismatch repair proficiency is not required for radioenhancement by gemcitabine International journal of radiation oncology, biology, physics 2005;62 (5):1504-1509 [PubMed]
All Publications
Research programmes

Prof. PhD J.P. Medema (Cell death induction and resistance in tumor cells)

PhD N.A.P. Franken (Combined ionizing radiation and hyperthermia treatment to improve cancer therapy)