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MD PhD J. Coutinho

Position
Medical Specialist
Main activities
Patient care, Research
Specialisation
Stroke neurologist
Focus of research

The Department of Neurology performs clinical and translational research within three research themes: infection & inflammation, cerebrovascular disorders, and movement disorders. .The themes are imbedded in the nine translational research programs of Amsterdam Neuroscience, the research institute of neuroscience investigators in the Amsterdam area. All staff members of the Department of Neurology are involved in research and collaborate within Neuroscience Amsterdam, with other academic and non-academic hospitals, and with international research groups.

Cerebrovascular Disorders
The Cerebrovascular Research Group focuses on the acute diagnostic and treatment options in both hemorrhagic and ischemic stroke, including aneurysmal subarachnoid hemorrhage and cerebral venous sinus thrombosis. Solving burning clinical questions is the starting point of the group, but where needed fundamental research is used to understand pathophysiology and develop new treatment strategies – from bed to bench and vice versa. To do so, the group has a strong clinical research infrastructure which runs large cohort studies and (international) multicenter randomized controlled trials which focus on the surveillance, testing and implementation of both new pharmacological and medical devices treatment options in acute stroke. Translational studies are focusing on early diagnostics of stroke subtypes, penumbral salvage/neuroprotection and reperfusion injury. The group is working together with all other major cerebrovascular research groups within the MR Clean and CONTRAST collaborations and is embedded in the cerebrovascular program of Amsterdam Neuroscience Center and is part of the Amsterdam Cardiovascular Sciences group.

Key publications
  • Coutinho Jonathan M., Liebeskind David S., Slater Lee-Anne, Nogueira Raul G., Clark Wayne, Dávalos Antoni, Bonafé Alain, Jahan Reza, Fischer Urs, Gralla Jan, Saver Jeffrey L., Pereira Vitor M. Combined Intravenous Thrombolysis and Thrombectomy vs Thrombectomy Alone for Acute Ischemic Stroke A Pooled Analysis of the SWIFT and STAR Studies JAMA Neurology 2017;74 (3):266-272 [PubMed]
  • Zuurbier Susanna M., Arnold Marcel, Middeldorp Saskia, Broeg-Morvay Anne, Silvis Suzanne M., Heldner Mirjam R., Meisterernst Julia, Nemeth Banne, Meulendijks Eva R., Stam Jan, Cannegieter Suzanne C., Coutinho Jonathan M. Risk of Cerebral Venous Thrombosis in Obese Women JAMA Neurology 2016;73 (5):579-584 [PubMed]
  • Coutinho Jonathan M., Zuurbier Susanna M., Aramideh Majid, Stam Jan The Incidence of Cerebral Venous Thrombosis A Cross-Sectional Study Stroke; a journal of cerebral circulation 2012;43 (12):3375-3377 [PubMed]
  • Coutinho Jonathan M., Ferro José M., Canhão Patrícia, Barinagarrementeria Fernando, Cantú Carlos, Bousser Marie-Germaine, Stam Jan Cerebral Venous and Sinus Thrombosis in Women Stroke; a journal of cerebral circulation 2009;40 (7):2356-2361 [PubMed]
  • Silvis Suzanne M., de Sousa Diana Aguiar, Ferro José M., Coutinho Jonathan M. Cerebral venous thrombosis Nature reviews. Neurology 2017;13 (9):555-565 [PubMed]
All Publications
Curriculum Vitae

Education

2014-2015:          Post-doctorate fellowship

Toronto Western Hospital – University of Toronto, Canada

After completing my clinical residencies in neurology at the Academic Medical Center in Amsterdam, I was accepted by professor Karel terBrugge to work at the Toronto Western Hospital as a post-doctorate research fellow. Here I lead various stroke-related research projects. The subjects of these projects include: endovascular treatment of ischemic stroke, intracranial vessel wall imaging for ischemic stroke and subarachnoid hemorrhage, non-stenotic carotid plaques in cryptogenic stroke, and cortical microhemorrhages in cerebral venous thrombosis. I am also still employed by the Academic Medical Center and continue to lead the AMC research group on cerebral venous thrombosis.

2007-2014:          Board Certification Neurology, Neurology Residency Program

                               Academic Medical Center – University of Amsterdam

                               Residency director: Prof. Dr. J. Stam

                               Board certified as a neurologist in the Netherlands as of 31 December 2014

                Specialization: stroke neurology (including a 6 month clinical fellowship in stroke neurology)

2007-2014:          Doctor of Philosophy (Ph.D.), stroke research

                      Title of thesis: Epidemiology, diagnosis and treatment of cerebral venous thrombosis

Academic Medical Center – University of Amsterdam

                              Promotor: Prof. Dr. J. Stam

2007:                     Doctor of Medicine (with honors)

                               Academic Medical Center – University of Amsterdam

2005:                     Master’s Degree in Biomedical Sciences (with honors)

                               University of Amsterdam

Current research funding
  • AMC
  • Boehringer Ingelheim BV
  • Elrohe BV
  • Erasmus MC
  • Hamilton Health Sciences Co.
  • Insel Gruppe AG
  • Medtronic Trading NL BV
  • Nederlandse Hartstichting
  • Portola Pharmaceuticals Inc.
  • Stichting Het Remmert Adriaan Laan Fonds
  • The George Institute for Global Health