M.R. Soeters MD PhD

Medical Specialist
Main activities
Patient care, Research
Endocrinology and Metabolism
Focus of research

(Patho)physiology of Energy Metabolism - Glucose/Lipid Metabolism


-Metabolic adaptation to starvation (i.e. insulin resistance of fasting)

-Acylcarnitines in the pathophysiology of insulin resistance

-Bile acid metabolism in the postprandial state

Key publications
  • van Nierop F. Samuel, Scheltema Matthijs J., Eggink Hannah M., Pols Thijs W., Sonne David P., Knop Filip K., Soeters Maarten R. Clinical relevance of the bile acid receptor TGR5 in metabolism Lancet. Diabetes and endocrinology 2017;5 (3):224-233 [PubMed]
  • Sonne David P., van Nierop F. Samuel, Kulik Willem, Soeters Maarten R., Vilsbøll Tina, Knop Filip K. Postprandial Plasma Concentrations of Individual Bile Acids and FGF-19 in Patients With Type 2 Diabetes Journal of clinical endocrinology and metabolism 2016;101 (8):3002-3009 [PubMed]
  • Schooneman Marieke G., ten Have Gabriella A. M., van Vlies Naomi, Houten Sander M., Deutz Nicolaas E. P., Soeters Maarten R. Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism American journal of physiology. Endocrinology and metabolism 2015;309 (3):E256-E264 [PubMed]
  • Schooneman Marieke G., Vaz Frédéric M., Houten Sander M., Soeters Maarten R. Acylcarnitines: reflecting or inflicting insulin resistance? Diabetes 2013;62 (1):1-8 [PubMed]
  • Soeters Maarten R., Soeters Peter B., Schooneman Marieke G., Houten Sander M., Romijn Johannes A. Adaptive reciprocity of lipid and glucose metabolism in human short-term starvation American journal of physiology. Endocrinology and metabolism 2012;303 (12):E1397-E1407 [PubMed]
All Publications
Curriculum Vitae

Maarten Soeters (1975) is an endocrinologist who is interested in translating basal research to the human situation. He studied at the University of Amsterdam where he also commenced training in internal medicine. He obtained his PhD in 2008 on the metabolic response to short-term fasting. The thesis included human translational work with stable isotopes and different clamp techniques.

After finishing his training he worked as an post-doc at the University of Cambridge in the United Kingdom (2011-2014) where he investigated the thermogenic response to cold and food components and the involved central and peripheral mechanisms that regulate thermogenesis and energy expenditure. This post-doc was funded by the Marie-Curie EU grant.

After rejoining the Department of Endocrinology and Metabolism of the Academic Medical Center in Amsterdam, he focused on acylcarnitine and bile acid metabolism (funded by an AMC PhD scholarship and the dutch Diabetes Foundation respectively). His primary interest is to increase the understanding of the postprandial metabolic and endocrine mechanisms that are important for a normal anabolic response. Additionally he is interested in total parenteral nutrition and the (patho)physiology of insulin resistance. Also patient care and teaching are core tasks of his appointment.

In 2015 he joined the editorial board of the journal "Clinical Nutrition".

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Research programmes

M.R. Soeters MD PhD (Postprandial metabolism and nutrition)

Medewerkers buiten research programmes van afdeling Inwendige Geneeskunde: Endocrinologie