J.R. Mekkes MD PhD

Medical Specialist
Main activities
Patient care, Other
Focus of research

Treatment of severe hidradenitis suppurativa with TNF-alpha inhibitors

Off-label use of TNF-alpha inhibitors in Dermatology

Clinical studies on woundhealing

Development of guidelines for the diagnosis and treatment of skin diseases

Diagnostic approach in patients with chronic urticaria


Key publications
  • Mekkes J. R., Bos J. D. Long-term efficacy of a single course of infliximab in hidradenitis suppurativa British journal of dermatology 2008;158 (2):370-374 [PubMed]
  • Mekkes Jan R., Loots Miriam A., van der Wal Allard C., Bos Jan D. Increased incidence of hypercoagulability in patients with leg ulcers caused by leukocytoclastic vasculitis Journal of the American Academy of Dermatology 2004;50 (1):104-107 [PubMed]
  • Mekkes J. R., Loots M. A. M., van der Wal A. C., Bos J. D. Causes, investigation and treatment of leg ulceration British journal of dermatology 2003;148 (3):388-401 [PubMed]
  • Kozel Martina M. A., Bossuyt Patrick M. M., Mekkes Jan R., Bos Jan D. Laboratory tests and identified diagnoses in patients with physical and chronic urticaria and angioedema: A systematic review Journal of the American Academy of Dermatology 2003;48 (3):409-416 [PubMed]
  • Loot Miriam A. M., Kenter Susan B., Au Fung L., van Galen W. J. M., Middelkoop Esther, Bos Jan D., Mekkes Jan R. Fibroblasts derived from chronic diabetic ulcers differ in their response to stimulation with EGF, IGF-I, bFGF and PDGF-AB compared to controls European journal of cell biology 2002;81 (3):153-160 [PubMed]
All Publications
Research programmes


(Medewerkers buiten research programmes van afdeling Dermatologie)