foto

PhD J.H.M. Levels

Position
Support Staff
Main activities
Research
Specialisation
Lipid metabolism, Proteomics, Hemostasis
Focus of research

Hemostasis and  Lipid Metabolism

Key publications
  • Raterman Hennie G., Levels Han, Voskuyl Alexandre E., Lems Willem F., Dijkmans Ben A., Nurmohamed Michael T. HDL protein composition alters from proatherogenic into less atherogenic and proinflammatory in rheumatoid arthritis patients responding to rituximab Annals of the rheumatic diseases 2013;72 (4):560-565 [PubMed]
  • Levels Johannes H. M., Geurts Pierre, Karlsson Helen, Maree Raphael, Ljunggren Stefan, Fornander Louise, Wehenkel Louis, Lindahl Mats, Stroes Erik S. G., Kuivenhoven Jan A., Meijers Joost C. M. High-density lipoprotein proteome dynamics in human endotoxemia Proteome science 2011;9 (1):34 [PubMed]
  • Holleboom Adriaan G., Karlsson Helen, Lin Ruei-Shiuan, Beres Thomas M., Sierts Jeroen A., Herman Daniel S., Stroes Erik S. G., Aerts Johannes M., Kastelein John J. P., Motazacker Mohammad M., Dallinga-Thie Geesje M., Levels Johannes H. M., Zwinderman Aeilko H., Seidman Jonathan G., Seidman Christine E., Ljunggren Stefan, Lefeber Dirk J., Morava Eva, Wevers Ron A., Fritz Timothy A., Tabak Lawrence A., Lindahl Mats, Hovingh G. Kees, Kuivenhoven Jan Albert Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man Cell metabolism 2011;14 (6):811-818 [PubMed]
  • Bartuzi Paulina, Billadeau Daniel D., Favier Robert, Rong Shunxing, Dekker Daphne, Fedoseienko Alina, Fieten Hille, Wijers Melinde, Levels Johannes H., Huijkman Nicolette, Kloosterhuis Niels, Van der Molen Henk, Brufau Gemma, Groen Albert K., Elliott Alison M., Kuivenhoven Jan Albert, Plecko Barbara, Grangl Gernot, McGaughran Julie, Horton Jay D., Burstein Ezra, Hofker Marten H., van de Sluis Bart CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL Nature communications 2016;7:10961 [PubMed]
All Publications
Curriculum Vitae

1987: HLO Technician, training at ZLS Zuid Nederland

 

1996: Master in Chemistry, Biochemistry (Faculty of Chemistry, University of Amsterdam)

 

2002: PhD. Thesis: Lipoproteins in innate immunity. (Faculty of Medicine, University of Amsterdam)

 

Research programmes

Prof. MD PhD M. Nieuwdorp (Gutmicrobiota as novel diagnostic and therapeutic targets in cardiometabolism)