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PhD J.P.M. Derikx

Position
Medical Specialist
Main activities
Patient care, Research
Specialisation
Paediatric surgeon with strong interest in translational research
Focus of research

Translational research with the aim to reveal pathophysiology of intestinal ischemia-reperfusion, anastomotic leakage and intestinal maturation (including the derailment of the inflammatory response leading to necrotizing enterocolitis).

Key publications
  • Grootjans Joep, Lenaerts Kaatje, Buurman Wim A., Dejong Cornelis H. C., Derikx Joep P. M. Life and death at the mucosal-luminal interface: New perspectives on human intestinal ischemia-reperfusion World journal of gastroenterology 2016;22 (9):2760-2770 [PubMed]
  • Derikx J. P. M., Kramer B. W., Wolfs T. G. A. M. Are EGF and TLR-4 crucial to understanding the link between milk and NEC? Mucosal immunology 2015;8 (5):979-981 [PubMed]
  • Reisinger Kostan W., Poeze Martijn, Hulsewé Karel W. E., van Acker Bernadette A., van Bijnen Annemarie A., Hoofwijk Anton G. M., Stoot Jan H. M. B., Derikx Joep P. M. Accurate Prediction of Anastomotic Leakage after Colorectal Surgery Using Plasma Markers for Intestinal Damage and Inflammation Journal of the American College of Surgeons 2014;219 (4):744-751 [PubMed]
  • Grootjans Joep, Hodin Caroline M., de Haan Jacco-Juri, Derikx Joep P. M., Rouschop Kasper M. A., Verheyen Fons K., van Dam Ronald M., Dejong Cornelis H. C., Buurman Wim A., Lenaerts Kaatje Level of Activation of the Unfolded Protein Response Correlates With Paneth Cell Apoptosis in Human Small Intestine Exposed to Ischemia/Reperfusion Gastroenterology 2011;140 (2):529-U248 [PubMed]
  • Derikx J. P. M., Evennett N. J., Degraeuwe P. L. J., Mulder T. L., van Bijnen A. A., van Heurn L. W. E., Buurman W. A., Heineman E. Urine based detection of intestinal mucosal cell damage in neonates with suspected necrotising enterocolitis Gut 2007;56 (10):1473-1475 [PubMed]
All Publications
Research programmes

PhD J.P.M. Derikx (Compromised gut in neonates and children.)

PhD Students
J.W. Bosmans
I.H. Hundscheid
A.C. Jongen
M. Kremer
C.A. Leenarts
D.H.S.M. Schellekens

Current research funding
  • AMC
  • Europese Unie
  • ZonMw