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Prof. dr. C.L.H. Bockting PhD

Position
Professor
Main activities
Research, Patient care
Specialisation
Clinical Psychology
Focus of research

My research program focuses on depressive disorder and related common mental health disorders. These disorders are characterized by disruptions in emotions. I study potentially modifiable etiological affective-, and information processing mechanisms on an intra-, as well as, interindividual level. 

My research program focuses on the following issues:

1) Understanding the complexity of etiological and maintenance factors in depression and related common mental health disorders.

2) Evaluating the effect of psychological interventions and combined interventions within RCT’s and micro-RCT’s (ecological momentary assessment and affective networks).

3) Innovative multimodal psychological interventions (i.e. combined with technological devices and pharmacological and other treatments) targeted at specific mechanisms underlying individual/subgroup differences in symptomatology. 

4) Increasing accessibility of effective psychological interventions using technology (for instance mobile interventions in low SES groups and low-, and middle income countries).

 

Key publications
  • Arjadi R, Nauta MH, Scholte WF, Hollon SD, Chowdhary N, Suryani AO, Uiterwaal CSPM, Bockting CLH, Internet-based behavioural activation with lay counsellor support versus online minimal psychoeducation without support for treatment of depression: a randomised controlled trial in Indonesia. LANCET PSYCHIAT 2018;5 (9):707-716 [PubMed]
  • Bockting CLH, Klein NS, Elgersma HJ, van Rijsbergen GD, Slofstra C, Ormel J, Buskens E, Dekker J, de Jong PJ, Nolen WA, Schene AH, Hollon SD, Burger H, Effectiveness of preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in prevention of depressive relapse or recurrence (DRD study): a three-group, multicentre, randomised controlled trial. LANCET PSYCHIAT 2018;5 (5):401-410 [PubMed]
  • Holmes EA, Ghaderi A, Harmer CJ, Ramchandani PG, Cuijpers P, Morrison AP, Roiser JP, Bockting CLH, O'Connor RC, Shafran R, Moulds ML, Craske MG, The Lancet Psychiatry Commission on psychological treatments research in tomorrow's science. LANCET PSYCHIAT 2018;5 (3):237-286 [PubMed]
All Publications
Curriculum Vitae

Please visit www.claudibockting.com for my curriculum vitae, more information about my research and the most recent publications.

 

Academic and clinical career:

2017 – current Professor of Clinical Psychology in Psychiatry, Department of Psychiatry, Academic Medical Center, Amsterdam.

 

Ancillary activities:

2018 - current: Advisory board NWO, Wetenschappelijk adviescollege (WAC), domein Sociale-en Geesteswetenschappen.

2017 - current: Advisory board 'Zorginstituut Nederland'. Wetenschappelijke advies raad (WAR).

2017 - current: Supervisory board Arkin Amsterdam.

2017 - current; Board member European Association of Clinical Psychology and Psychological Treatment (EACLIPT) (non-paid)

2003 - current: Incidental workshops and senior lecturer clinical postdoctoral courses for psychologists (GZ, KP, KNP).

  

Academic grants:

2018  Does time heal everything? A complex dynamical systems approach to emotional functioning and relapse in depression. NWO research talent M. Eijlander, prof. C.L.H. Bockting (PI), prof. P.M.A. Sloot (IAS), Prof. A. Hayes (University of Delaware, USA).
 

2018 Establishment Grants: Resilience in Recurrent Depression: The Role of Successful Stress Recovery in Long-Term Remission. Saskatchewan Health Research Foundation. PI: dr. S. Beshai, University of Regina, Canada; Co-applicant: Bockting, C. L. H.
 

2018 Determining effective relapse prevention strategies for recurrent depression and moderators of treatment outcome – what works for whom? Bockting, C. L. H. (AMC), APH Mental Health alliance. J. Breedvelt (AMC), van Oppen (VUmc).
 

2018 MENTALLY: Improving access to mental health care and mental health literacy. European Commission CONSUMERS, HEALTH, AGRICULTURE AND FOOD EXECUTIVE AGENCY Health Programme, PP2-2016, PI A. DeWaele, Experimental Clinical and Health Psychology, Ghent University, Belgium.
 

2017 STAY FINE: a personalized monitoring and intervention app to prevent relapse of
anxiety and mood disorders in youth and young adults. Role: Bockting, C. L. H. primary promotor AMC, co-applicant. In coll. with Y.A.J. Stikkelbroek (PI) and M.H. Nauta. ZonMW, RuG, AMC.
 

2017 Relapse prevention in depression: a dissementation project. ZON-MW, VIMP. 2017-2018. Bockting, C. L. H. (PI).
 

2017 Unraveling co-morbidity in mental health disorders; personalised affective models and multi modal personalised interventions in co-morbid conditions. Arq trauma institute. Bockting, C. L. H. (PI),
 

2017 UU, Ndlovu Research Consortium and University of the Witwatersrand, Johannesburg. Beating co-morbidity using mobile interventions: Depression in HIV in rural and urban South Africa and the potential for other low/middle income countries. PhD proposal. Bockting, C. L. H. (PI).
 

2016 The Effect of App based Behavioural Therapy on Emotional Inertia among Chinese Depressive Adults: A Randomized Controlled Trial Study. China Scholarship Council fund 2016-2020. Bockting, C. L. H. (PI), PhD student Z. Fu.
 

2016 NIAS research Theme group (PI, Bockting, C. L. H., 5 months): My optimism wears heavy boots: So much research, so few implications, towards ‘patient-proof’ empirical models and more effective interventions in mental health.
In collaboration with professor E.A. Holmes, Medical Research Council Cognition and Brain Sciences Unit (MRC CBU), Cambridge, UK and Karolinska Institute, Sweden, professor C. Harmer, professor of Cognitive Neuroscience, University of Oxford, UK, professor S.D. Hollon, professor of Psychology and Psychiatry, Vanderbilt University, USA, associate professor G. Siegle, Departments of Psychiatry, Psychology, and Translational Sciences, University of Pittsburgh School of Medicine, USA, H. Tiemeijer, professor of Psychiatric Epidemiology, Erasmus University, associate professor A. Cramer, Department of Methodology, University of Amsterdam, dr. C. Vinkers assistant professor at the Department of Psychiatry of the University Medical Center in Utrecht, professor M. van den Hout, professor of Experimental Psychopathology at Utrecht University and Ph. Spinhoven, professor of Clinical Psychology, Leiden University. Personal fellowship.

2016 Diagnostics and multi-modal intervention for victims of human trafficking (2016-2017), In collaboration with Arq Psychotrauma expertise center, Equator, dr. Pim Scholte.
 

2016 Recovery and personalised models and treatment for refugees with mental health problems (2016-2017). In collaboration with Arq. In collaboration with Arq Psychotrauma expertise center, Equator, dr. Pim Scholte.
 

2015 I make you smile: Using facial expression to detect and tackle depression. Seed Money 2016 UU. With Alishia Williams and the department of Information and Computer Sciences; Ronald Poppe.
 

2015 Differential Efficacy of Supportive-Expressive and Cognitive Behavioral Interventions in Dependent and Self-critical Depressive Patients: A Randomized Controlled Trial. Ghent University (SCS RCT). In collaboration with dr. R. Meganck (Ghent University). PhD trajectory.
 

2015 Predicting and Understanding Neurocognitive Mechanisms of Relapse Prevention: a randomized controlled trial of preventive cognitive therapy in remitted Major Depressive Disorder using fMRI and pupillometry. NWO VENI grant, Hersenstichting Nederland (HS) ass. prof. M.J. van Tol (PI). In collaboration with UMCG (R.S. van Kleef, and prof. A. Aleman).
 

2014  Stop or Go? Tapering antidepressants in pregnancy: a pragmatic multicenter RCT to investigate risk and benefits for mother and child. ZonMW/NWO Goed Geneesmiddelen Gebruik. In collaboration with Psychiatry (assoc. prof. M. van de Berg, Erasmus University; PI, prof. C.L.H. Bockting Co-PI, UU) and UMCG (assoc. prof. H. Burger; UMCG).
 

2014  Victimization in depressed patients; the role of emotion regulation. NWO. In collaboration with VUmc, Arkin (prof. A. Beekman PI, prof. J. Dekker, dr. M. Kikkert, dr. R. Van, dr. A. van Schaik, C. Christ (Phd candidate).
 

2013  The effectiveness of online behavioural activation led by lay health counsellors for depression in The Netherlands and Indonesia. (PI). Indonesian national research fund. In collaboration with the London school of Hygiene and Tropical Medicine and Sangath (assoc. prof. N. Chowdhary, London, UK, Goa, India), Vanderbilt University (prof. S.D. Hollon; Nashville, USA) and Equator/Arq Psychotrauma Expert group (P. Scholte) and ass. prof. M.H. Nauta (RuG) PhD candidate: R. Arjadi.
 

2013  Blended internet based CBT for children with anxiety disorders: what can individual changes tell us? ZonMW Effectief jeugd. In collaboration with Acarre, RuG (prof. P. Kendall; Tempel University, USA, Ass. prof. M. Nauta, PI; ass. prof. B. van de Hoofdakker; RuG), and de Bascule (prof. E. de Haan; AMC, UvA). Postdoc: dr. G. Kok.
 

2013  Prescribing blended care combining face-to-face contacts with web-based guided self-help instead of antidepressants for depression in general practice; a cluster randomized pragmatic trial. ZonMW/NWO. In collaboration with the department of general practice. Assoc. prof. H. Burger (PI; UMCG).
 

2012 Work on your imagination: An innovative approach to depression, targeting emotions using imagery. NWO. In collaboration with MRC Cognition and Brain sciences unit, University of Cambrigde/Karolinska Institute (prof. E. Holmes, UK). PhD student: C. Slofstra. Bockting, C. L. H. (PI).
 

2011  Effectiveness of continuation CT in preventing relapse in depression. NWO/ZonMW. In collaboration with mental health care center Amsterdam: Arkin (prof. J. Dekker, PI) and VU University. PhD candidate: M. de Jonge. Amount: 347,000 euro.
 

2011  Evaluation of online-based relapse prevention Intervention in Patients with Major Depressive Disorder. Role: advisor. BMBF. Ch diseases and orientation towards patients. In collaboration with prof. M. Berking (PI) and ass. prof. D. Ebert (Marburg University, Germany), 2011.
 

2010  Effectiveness of monitoring and nurse delivered preventive CT in preventing relapse in depression in primary care. NWO/ZonMW. In collaboration with VU University General practice department, primary care (assoc. prof. H. van Marwijk, PI).
 

2010 Effects of cognitive behavioural therapy for antenatal depression and anxiety on physical birth outcomes. ZonMW. In collaboration with the department of general practice UMCG Groningen/OLVG Amsterdam (Prof. M. Berger; PI and assoc. prof. H. Burger). Costs MD/PhD trajectory T. Verbeek.
 

2009 Cost-effectiveness of an e-mental health self-management intervention with automated tele-monitoring for recurrent depression and co-morbidity with chronic somatic disorders. (Bockting, C. L. H., PI), ZonMW disease management chronic diseases. In collaboration with the University of Pennsylvania (prof. A.T. Beck, USA), VU University (general practice department and clinical psychology; prof. H. Riper, prof. P. Cuijpers), Trimbos institute Utrecht (prof. F. Smit) and several mental health care centers.
 

2009 Cost-effectiveness of tapering antidepressants versus preventive cognitive therapy and the combination of comtinuation of antidepressants with preventive cognitive therapy. (Bockting, C. L. H., PI). ZonMW Doelmatigheid K&E. In collaboration with the Beck Institute USA (prof. A.T. Beck, USA), Vanderbilt University (prof. S.D. Hollon, USA, Second promoter), University of Maastricht, Psychiatry UMCG Groningen, University of Amsterdam AMC, Amsterdam, Erasmus University, Department of work related disorders (AMC) and several mental health care centers. PhD student G. van Rijsbergen.
 

2008  Disrupting the rhythm of depression: Effectiveness and cost-effectiveness and mediating  factors of preventive cognitive therapy in the prevention of recurrent major depressive disorder. (Bockting, C. L. H., PI). ZonMW, OOG (PhD student H. Elgersma). In collaboration with the Beck Institute USA (dr. A.T. Beck, USA), Vanderbilt University, University of Maastricht, Psychiatry UMCG Groningen, University of Amsterdam AMC, Amsterdam, Erasmus University, Department of work-related disorders (AMC) and several mental health care centers). Amount: 210,000 euro.
 

2008  Prevention of psychosocial problems in the offspring of mothers with symptoms of depression or anxiety during pregnancy: benefits for mother and child. (Co-PI). ZonMW. In collaboration with the departments of Epidemiology, Psychiatry and Gyneacology UMCG and department of general practice (ass. prof. H. Burger H.; PI), PhD student RuG: J. Meijer. PhD student UMCG: C. Beijer.
 

2008  Internet-supported self-management of recurrent depression with automated monitoring of health outcomes: demonstration project and evaluation. VWS/ZonMW. In collaboration with Trimbos institute and mental health care center Amsterdam, prof. J. Dekker (Arkin/VU), and prof. F. Smit (VU).
 

2008  Effectiveness and cost-effectiveness of cognitive therapy in Inflammatory Bowel Disease, a multi-center trial. MLD. In collaboration with the department of Medical Psychology (prof. M. Sprangers, AMC, University of Amsterdam; prof. R. Sanderman UMCG, RUG).
 

2008  Improving diagnosis and prognosis in bipolar and unipolar patients: the role of fMRI to determine biomarkers in addition to clinical measurements. NWO/ZonMW, OOG. In collaboration with Rive, M., Ruhé, H.G., prof. A. Schene, A.H., prof. D. Veltman (AMC, University of Amsterdam).
 

2008  Preventing anxiety and mood disorders in youth: a multi-center prevention trial in high risk offspring of anxious and depressed patients. NWO/ZonMW Preventie. In collaboration with ass. prof. Nauta M. (PI), project member, UMCG Psychiatry and Accare.
 

2001  Somatic, psychological and social course in patients with recurrent depression. Nationaal Fonds Geestelijke Volksgezondheid. In collaboration with prof. A. Schene and prof. Ph. Spinhoven. 

 

Ongoing PhD’s

  • Maartje Eijlander (January 2019-January 2023). Does time heal everything? A complex dynamical systems approach to emotional functioning and relapse in depression. NWO research talent. (primary supervisor, ’eerste promotor’ in collaboration with prof. P.M.A. Sloot (IAS, UvA), Prof. A. Hayes (University of Delaware, USA).
  • Josefien Breedvelt (September 2017-September 2021). Preventing onset and recurrence in common mental health disorders. (primary supervisor, ’eerste promotor’ in collaboration with the Mental Health Foundation (London) and prof.  Simon Gilbody, York University, UK).
  • Zhongfang Fu (October 2016-October 2020). The Effect of App-Based Cognitive Behavioural Therapy on Emotional Inertia among Chinese Depressive Adults: A Randomized Controlled Trial Study. (primary supervisor ‘eerste promotor’).
  • Nicola Klein (2013-2018; planned dissertation 21 March 2019). Multi modal interventions for relapse prevention in depression and cost effectiveness (parttime PhD, primary supervisor; ‘eerste promotor’).
  • Marlies Brouwer (2014-2018; planned dissertation 7 June 2019). Stop or go? Tapering antidepressants in pregnancy: a pragmatic multicenter RCT to investigate risk and benefits for mother and child. (primary supervisor; ‘eerste promotor’).
  • Hermien Elgersma (2008-2018; planned dissertation December 2018). Implicit and explicit self-association in depression. (part-time PhD, primary supervisor; ‘eerste promotor’)
  • Margo de Jonge (2011-2018; planned dissertation 2019). Prevention of relapse and the effect of continuation cognitive therapy. (parttime PhD, shared supervisor VU; ‘tweede promotor’).

 

 

Former PhD’s

  • Retha Arjadi (2013-2018; defense 13 December 2018). The effectiveness of behavioural activation led by lay health counsellors for depression and the value of
  • momentary assessment of mood as predictor for treatment response in The Netherlands and Indonesia. (primary supervisor; ‘eerste promotor’).
  • Nina Molenaar (2014-2018; PhD defence 21 November 2018). Antidepressants in the Perinatal Period: challenging choices in current practice. (in collaboration with Witte Hoogendijk, Erasmus MC, secundary supervisor; ‘tweede promotor’).
  • Christien Slofstra (2012-2017; PhD defense 30 November 2017). Moving onwards: Affective change, mental imagery, and depressive relapse (primary supervisor; eerste promotor’).
  • Floor Bennebroek Evertsz (2009-2017; PhD defense 1 December 2017). The effectiveness of cognitive behavioral therapy on the quality of life and anxiety and depression in patients with inflammatory bowel disease. (part-time PhD, shared supervisor UvA/AMC; ‘tweede promotor’).
  • Lonneke van Tuil (2012-2017: PhD defence 18 May 2017). Self-esteem in depression and anxiety: low, unstable, and discrepant? (shared supervisor with Prof. de Jong; ‘tweede promotor’, RuG).
  • Tjitte Verbeek (2011-2016; MD/PhD, PhD defence 20 January 2016). The effect of psychological interventions in pregnant women on somatic outcomes in their offspring. (shared supervisor with Prof. Berger; ‘tweede promotor’, UMCG).
  • Judith Meijer (2009-2015; PhD defence 23 November 2015). Depressive and anxiety symptoms during pregnancy and the effect of perinatal psychological interventions. (primary supervisor; ‘eerste promotor’).
  • Gerard van Rijsbergen (2010-2014; PhD defence 18 December 2014). How do you feel? Understanding the impact of emotion and cognition on course of depressive symptomatology. (primary supervisor; ‘eerste promotor’).
  • Chantal Beijers (2011-2014; PhD defence 20 October 2014). Why do pregnant woman (not) smoke and drink? The role of personality, stress and pregnancy related life events. (shared supervisor; ‘tweede promotor’ RuG/UMCG).
  • Marielle Hendriksen (2007-2014; PhD defence 9 October 2014). Pieces of a clinical puzzle: analyzing the alliance in psychodynamic psychotherapy for depression. Therapeutic technique, alliance, personality and therapist characteristics. (shared supervisor VU; ‘tweede promotor’).
  • Gemma Kok (2009-2014; PhD defence 29 September 2014). Under pressure: Pathways to relapse in depression, the role of stress and trauma. (primary supervisor; ‘eerste promotor’).
  • Anja Lok (2008-2012; PhD defence 9 December 2013). Time after time; biological factors in the course of recurrent depression. (shared supervisor; ‘tweede promotor’, UvA/AMC).
  • Mascha ten Doesschate (2006-2009; PhD defence 18 November 2009). Adherence, quality of life and risk factors in recurrent depression. (‘co-promotor’).
  • Marielle Hendriksen (2007-2014; finished 9 October 2014). Pieces of a clinical puzzle: analyzing the alliance in psychodynamic psychotherapy for depression. Therapeutic technique, alliance, personality and therapist characteristics. (shared supervisor VU; ‘tweede promotor’).
  • Gemma Kok (2009-2014; finished 29 September 2014). Under pressure: Pathways to relapse in depression, the role of stress and trauma. (primary supervisor; ‘eerste promotor’).
  • Anja Lok (2008-2012; finished 9 December 2013). Time after time; biological factors in the course of recurrent depression. (shared supervisor; ‘tweede promotor’, UvA/AMC).
  • Mascha ten Doesschate (2006-2009; finished 18 November 2009). Adherence, quality of life and risk factors in recurrent depression. (‘co-promotor’).

     
Research programmes

Prof. dr. D.A.J.P. Denys (Deep Brain Stimulation and Obsessive-Compulsive Disorders)

Other research related activities
  • Board of directors / Trustees / Supervisory board, Arkin
  • Membership of advisory board / Consultant, National Health Institute (Zorginstituut Nederland), Scientific Advisory Board (WAR)
  • Membership of advisory board / Consultant, NWO,Scientific Advisory Board (WAC), domain Social Science and Humanities
  • Speakers bureau / Lectures, Incidental workshops and senior lecturer clinical postdoctoral courses for psychologists (GZ, KP, KNP)
  • Other, Board member European Association of Clinical Psychology and Psychological Treatment (EACLIPT)