Prof. dr. G.K. Hovingh MD PhD

Main activities
Research, Patient care, Teaching
Lipid metabolism, Genetics
Focus of research
The focus of my research is the molecular basis of inherited dyslipidemias and novel therapies.

Key publications
  • Sjouke B, Kusters DM, Kindt I, Besseling J, Defesche JC, Sijbrands EJG, Roeters van Lennep JE, Stalenhoef AFH, Wiegman A, de Graaf J, Fouchier SW, Kastelein JJP, Hovingh GK, Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome. EUR HEART J 2015;36 (9):560-565 [PubMed]
  • Motazacker MM, Peter J, Treskes M, Shoulders CC, Kuivenhoven JA, Hovingh GK, Evidence of a polygenic origin of extreme high-density lipoprotein cholesterol levels. ARTERIOSCL THROM VAS 2013;33 (7):1521-1528 [PubMed]
  • Besseling J, Kastelein JJP, Defesche JC, Hutten BA, Hovingh GK, Association Between Familial Hypercholesterolemia and Prevalence of Type 2 Diabetes Mellitus. JAMA-J AM MED ASSOC 2015;313 (10):1029-1036 [PubMed]
  • Hovingh GK, Kastelein JJP, van Deventer SJH, Round P, Ford J, Saleheen D, Rader DJ, Brewer HB, Barter PJ, Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial. LANCET 2015;386 (9992):452-460 [PubMed]
  • Rader DJ, Hovingh GK, HDL and cardiovascular disease. LANCET 2014;384 (9943):618-625 [PubMed]
All Publications
Research programmes

Genetics and Pathology of Atherosclerosis

Prof. dr. G.K. Hovingh MD PhD

PhD Students
C.S. Bruikman
A.J. Cupido MD MSc
M.L. Hartgers
L.F. Reeskamp MD
Mr. R.M. Stoekenbroek BSc
T.R.T.M. Tromp
R. Verbeek

Prof. J.J.P. Kastelein MD PhD (Vascular Medicine)

Prof. dr. E.S.G. Stroes MD PhD (Novel anti-atherogenic strategies targeting the vessel wall)

Other research related activities
  • Contribution to guidelines and protocols, EAS FH guideline
  • Membership of medical or scientific committee, Nederlandse Internisten Dagen commissie, Internisten dagen commissie
  • Membership of medical or scientific committee, Vascular Medicine, IVG nascholing commissie
  • Contribution to training of professionals, Commissie Onderwijs Interne Geneeskunde (COIG)
  • MBA trainee, MBA healthcare VUMC-AMC
Current research funding
  • Aegerion Pharmaceuticals SARL
  • AMC (Vrijgesteld)
  • Amgen BV
  • BioCryst Pharmaceuticals, Inc.
  • Boehringer Ingelheim BV
  • CSL Behring LLC
  • EAS European Atherosclerosis Society
  • Idorsia Pharmaceuticals Ltd.
  • Imperial College of Science Technology and Medicine
  • Medical Research BV
  • Portola Pharmaceuticals Inc.
  • Regeneron Pharmaceuticals, Inc.
  • Sanofi - Aventis Netherlands BV
  • Synageva BioPharma Corp.
  • Thrombosis Research Institute
  • UBC Late Stage (UK) Limited
  • UniQure Biopharma BV
  • Vascular Research Network BV
  • Zealand Pharma A/S
  • ZonMw