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Prof. MD PhD M. Nieuwdorp

Position
Full Professor
Main activities
Patient care, Research
Specialisation
Internal medicine/Endocrinology-Vascular Medicine
Focus of research

 

- role of gutmicrobiota in development of human obesity, insulin resistance and dyslipidemia
 

 

Key publications
  • Vrieze Anne, van Nood Els, Holleman Frits, Salojärvi Jarkko, Kootte Ruud S., Bartelsman Joep F. W. M., Dallinga-Thie Geesje M., Ackermans Mariette T., Serlie Mireille J., Oozeer Raish, Derrien Muriel, Druesne Anne, van Hylckama Vlieg Johan E. T., Bloks Vincent W., Groen Albert K., Heilig Hans G. H. J., Zoetendal Erwin G., Stroes Erik S., de Vos Willem M., Hoekstra Joost B. L., Nieuwdorp Max Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome Gastroenterology 2012;143 (4):913-+ [PubMed]
  • van Nood Els, Vrieze Anne, Nieuwdorp Max, Fuentes Susana, Zoetendal Erwin G., de Vos Willem M., Visser Caroline E., Kuijper Ed J., Bartelsman Joep F. W. M., Tijssen Jan G. P., Speelman Peter, Dijkgraaf Marcel G. W., Keller Josbert J. Duodenal infusion of donor feces for recurrent Clostridium difficile New England journal of medicine 2013;368 (5):407-415 [PubMed]
  • Li Simone S., Zhu Ana, Benes Vladimir, Costea Paul I., Hercog Rajna, Hildebrand Falk, Huerta-Cepas Jaime, Nieuwdorp Max, Salojärvi Jarkko, Voigt Anita Y., Zeller Georg, Sunagawa Shinichi, de Vos Willem M., Bork Peer Durable coexistence of donor and recipient strains after fecal microbiota transplantation Science 2016;352 (6285):586-589 [PubMed]
  • Kootte Ruud S., Levin Evgeni, Salojärvi Jarkko, Smits Loek P., Hartstra Annick V., Udayappan Shanti D., Hermes Gerben, Bouter Kristien E., Koopen Annefleur M., Holst Jens J., Knop Filip K., Blaak Ellen E., Zhao Jing, Smidt Hauke, Harms Amy C., Hankemeijer Thomas, Bergman Jacques J. G. H. M., Romijn Hans A., Schaap Frank G., Olde Damink Steven W. M., Ackermans Mariette T., Dallinga-Thie Geesje M., Zoetendal Erwin, de Vos Willem M., Serlie Mireille J., Stroes Erik S. G., Groen Albert K., Nieuwdorp Max Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition Cell metabolism 2017;26 (4):611-+ [PubMed]
All Publications
Curriculum Vitae

2002 MD (Utrecht University)

 

2007 PhD (AMC-Univerisity of Amsterdam,promotor: Prof J.J.P. Kastelein)

 

2007-2008 Postdoctoral fellow University of California San Diego (Glycobiology research center, prof J. Esko)

2008 VENI-ZONMW grant

2012 Registration Internist-Endocrinologist

 

2012-  Associate professor Vascular Medicine

 

2013-2018 Visiting Professor Sahlgrenska University Hospital, Gothenborg University (Prof F. Backhed)

 

2014- Chief Laboratory of Experimental Vascular Medicine, AMC-UvA

 

2014 VIDI-ZONMW grant

2015 Professor Internal Medicine  AMC-UvA

 

Research programmes

Prof. MD PhD M. Nieuwdorp (Gutmicrobiota as novel diagnostic and therapeutic targets in cardiometabolism)

Our group focuses on the role of intestinal microbiota in chronic inflammation and human cardiometabolism in a translational fashion. We aim to find novel pathophysiological pathways driving cardiovascular disease, dyslipidemia and diabetes mellitus studying the role of baceria in adipose tissue, liver (NASH) and macrovascular inflammation. In line, we will try to identify novel therapeutic targets via identifying bacterial ligands or developing novel probiotic bacterial strains and vaccination leads to treat these diseases.

Faculty
MEng PhD G.M. Dallinga-Thie
Prof. PhD A.K. Groen
PhD J.H.M. Levels
PhD E. Levin
Prof. MD PhD E.S.G. Stroes
Prof. PhD N.A.W. van Riel

Postdocs
PhD M. Davids
PhD H.J. Herrema
MEng PhD S.K. Imangaliyev
PhD A. Prodan

PhD Students
K. Fluitman
MSc T. Scheithauer
MD M.J.B. van Baar
MD L. van Ruiten

Others
BSc J.C. Borger
MEng S.R. Havik
BEng J.P. Jansen
R. Schmitz
BEng M. Versloot
BEng M. Winkelmeijer
BSc D. Zwirs

Prof. MD PhD E.S.G. Stroes (Novel anti-atherogenic strategies targeting the vessel wall)

Current research funding
  • AMC
  • AMC (Vrijgesteld)
  • Amsterdam Gastroenterology and Metabolism Res. Institute
  • BioCryst Pharmaceuticals, Inc.
  • CSL Behring LLC
  • Europese Unie
  • Fondation Leducq
  • Gilead Sciences
  • Life Sciences Health TKI
  • Nederlandse Hartstichting
  • Novo Nordisk B.V.
  • Orion Clinical Services Limited
  • Stichting AMC Foundation (Vrijgesteld)
  • Technical University of Denmark
  • The Novo Nordisk Foundation Center
  • Vascular Research Network BV
  • ZonMw