MD MSc PhD R.J.T. Mocking

Other Academic Staff
Main activities
Education, Patient care, Research
Biological psychiatry
Focus of research

As a Postdoc I have a broad interest in applying research to personalise psychiatry and provide an evidence base for daily clinical practice.

My PhD focused on endocrinological and metabolic alterations in depression. By applying interdisciplinary and multimodal methods we linked fatty acids to HPA-axis functioning and neuroimaging. Findings, including our meta-analyses, suggest that dietary omega-3 fatty acids can improve antidepressant effectivity. This was implemented in the Dutch guidelines and the diet served at the department of psychiatry of the AMC now includes more omega-3 fatty acids. 

During my Postdoc I am involved in research on deep brain stimulation for psychiatric disorders in the Denys group. In addition I perform a literature study on physical and pharmacological restraints in hospital care.

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Key publications
  • Mocking R. J. T., Nap T. S., Westerink A. M., Assies J., Vaz F. M., Koeter M. W. J., Ruhé H. G., Schene A. H. Biological profiling of prospective antidepressant response in major depressive disorder: Associations with (neuro)inflammation, fatty acid metabolism, and amygdala-reactivity Psychoneuroendocrinology 2017;79:84-92 [PubMed]
  • Mocking R. J. T., Harmsen I., Assies J., Koeter M. W. J., Ruhé H. G., Schene A. H. Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder Translational psychiatry 2016;6:e756 [PubMed]
  • Rive Maria M., Mocking Roel J. T., Koeter Maarten W. J., van Wingen Guido, de Wit Stella J., van den Heuvel Odile A., Veltman Dick J., Ruhé Henricus G., Schene Aart H. State-Dependent Differences in Emotion Regulation Between Unmedicated Bipolar Disorder and Major Depressive Disorder JAMA psychiatry 2015;72 (7):687-696 [PubMed]
  • Assies Johanna, Mocking Roel J. T., Pouwer François Maternal depression and child development after prenatal DHA supplementation JAMA 2011;305 (4):360; author reply 360-360; author reply 361 [PubMed]
All Publications
Curriculum Vitae

Available on request