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Dr. D. Amsen

Position
Scientific staff member (UD)
Main activities
Research
Specialisation
Immunology/regulation of transcription
Key publications
  • Helbig C, Gentek R, Backer RA, de Souza Y, Derks IAM, Eldering E, Wagner K, Jankovic D, Gridley T, Moerland PD, Flavell RA, Amsen D, Notch controls the magnitude of T helper cell responses by promoting cellular longevity. P NATL ACAD SCI USA 2012;109 (23):9041-9046 [PubMed]
  • Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF, ten Brinke A, Willemsen AM, van Kampen AHC, Kaech SM, Blander JM, van Gisbergen K, Amsen D, A central role for Notch in effector CD8(+) T cell differentiation. NAT IMMUNOL 2014;15 (12):1143-1151 [PubMed]
  • Hombrink P, Helbig C, Backer RA, Piet B, Oja AE, Stark R, Brasser G, Jongejan A, Jonkers RE, Nota B, Basak O, Clevers HC, Moerland PD, Amsen D, van Lier RAW, Programs for the persistence, vigilance and control of human CD8(+) lung-resident memory T cells. NAT IMMUNOL 2016;17 (12):1467-1478 [PubMed]
  • Nair-Gupta P, Baccarini A, Tung N, Seyffer F, Florey O, Huang Y, Banerjee M, Overholtzer M, Roche PA, Tampé R, Brown BD, Amsen D, Whiteheart SW, Blander JM, TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation. CELL 2014;158 (3):506-521 [PubMed]
  • Sander LE, Davis MJ, Boekschoten MV, Amsen D, Dascher CC, Ryffel B, Swanson JA, Müller M, Blander JM, Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. NATURE 2011;474 (7351):385-389 [PubMed]
All Publications
Research programmes

T cells for adoptive cellular therapy: fundaments and therapeutic application

Faculty
Dr. D. Amsen (Sanquin)

Postdocs
Dr. R.A. Backer
Dr. E. Cuadrado (Sanquin)
Dr. C. Helbig (Sanquin)
Dr. J. Karrich

PhD Students
R. Opstelten
Drs. W. Huisman (LUMC)

Others
M. Slot BSc (Sanquin)