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Dr. ir. A.L.M.A. ten Asbroek

Position
Scientific staff member (UD)
Main activities
Research, Teaching
Specialisation
molecular biology, stem cell biology
Focus of research

Modelling of complex genetic retinal disorders with the use of (induced) pluripotent stem cells

Key publications
  • Smith BN, Newhouse S, Shatunov A, Vance C, Topp S, Johnson L, Miller J, Lee Y, Troakes C, Scott KM, Jones A, Gray I, Wright J, Hortobágyi T, Al-Sarraj S, Rogelj B, Powell J, Lupton M, Lovestone S, Sapp PC, Weber M , Nestor PJ, Schelhaas HJ, ten Asbroek AA , Silani V, Gellera C, Taroni F, Ticozzi N, van den Berg L, Veldink J, van Damme P, Robberecht W, Shaw PJ, Kirby J, Pall H, Morrison KE, Morris A, de Belleroche J, de Jong JMBV, Baas F, Andersen PM, Landers J, Brown RH Jr, Weale ME, Al-Chalabi A, Shaw CE, The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder. EUR J HUM GENET 2013;21 (1):102-108 [PubMed]
  • Aronica E, Baas F, Iyer A, ten Asbroek ALMA, Morello G, Cavallaro S, Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex. NEUROBIOL DIS 2015;74:359-376 [PubMed]
  • Saavedra JT, Wolterman RA, Baas F, ten Asbroek ALMA, Myelination competent conditionally immortalized mouse Schwann cells. J NEUROSCI METH 2008;174 (1):25-30 [PubMed]
  • ten Asbroek ALMA, Verhamme C, van Groenigen M, Wolterman R, de Kok-Nazaruk MM, Baas F, Expression profiling of sciatic nerve in a Charcot-Marie-Tooth disease type 1a mouse model. J NEUROSCI RES 2005;79 (6):825-835 [PubMed]
  • Fluiter K, ten Asbroek ALMA, van Groenigen M, Nooij M, Aalders MCG, Baas F, Tumor genotype-specific growth inhibition in vivo by antisense oligonucleotides against a polymorphic site of the large subunit of human RNA polymerase II. CANCER RES 2002;62 (7):2024-2028 [PubMed]
All Publications
Research programmes

Prof. dr. F. Baas (Genome analysis / Neurogenetics)

Prof. dr. A.A.B. Bergen (Molecular etiology of complex genetic retinal disorders)