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Dr. J.A. Aten

Position
Scientific staff member (UD)
Main activities
Research
Specialisation
Interactions of DNA double strand breaks and repair proteins in the formation of chromosome transloc
Focus of research

Interactions of DNA double strand breaks and repair proteins in the formation of chromosome translocations and cell killing by ionizing radiation and other therapeutic agents.

Key publications
  • Aten JA, Stap J, Krawczyk PM, van Oven CH, Hoebe RA, Essers J, Kanaar R, Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. SCIENCE 2004;303 (5654):92-95 [PubMed]
  • Stap J, Krawczyk PM, van Oven CH, Barendsen GW, Essers J, Kanaar R, Aten JA, Induction of linear tracks of DNA double-strand breaks by alpha-particle irradiation of cells. NAT METHODS 2008;5 (3):261-266 [PubMed]
  • Manders EMM, Verbeek FJ, Aten JA, Measurement of co-localization of objects in dual-colour confocal images. J MICROSC-OXFORD 1993;169 (3):375-382
  • Williams ES, Stap J, Essers J, Ponnaiya B, Luijsterburg MS, Krawczyk PM, Ullrich RL, Aten JA, Bailey SM, DNA double-strand breaks are not sufficient to initiate recruitment of TRF2. NAT GENET 2007;39 (6):696-8; author reply 698-9 [PubMed]
  • Mir SE, de Witt Hamer PC, Krawczyk PM, Balaj L, Claes A, Niers JM, van Tilborg AAG, Zwinderman AH, Geerts D, Kaspers GJL, Vandertop WP, Cloos J, Tannous BA, Wesseling P, Aten JA, Noske DP, van Noorden CJF, Würdinger T, In Silico Analysis of Kinase Expression Identifies WEE1 as a Gatekeeper against Mitotic Catastrophe in Glioblastoma. CANCER CELL 2010;18 (3):244-257 [PubMed]
All Publications
Research programmes

Dr. J.A. Aten (Interactions of DNA double strand breaks and repair proteins in the formation of chromosome translocations)

Faculty
Dr. J.A. Aten

Postdocs
Dr. P.M. Krawczyk

Others
Dr. J. Stap