J.H. Akkerdaas PhD

Research Associate
Main activities
Allergy research
Focus of research
  • Protein-chemistry and molecular biology of respiratory and food allergens: what makes an allergen an allergen?
  • Innovative approaches for in vitro and in vivo diagnosis of IgE-mediated allergy: from allergen extracts to molecular diagnostics.
  • Innovative biopharmaceutical approaches for allergen-specific immunotherapy: recombinant technology, novel adjuvants and administration routes.
  • Immuno-epidemiology of respiratory and food allergies: the role of allergen exposure, environment, diet, infections and lifestyle in the development of allergy.
  • Mouse models of allergy and asthma: how are sensitization and disease expression regulated?


Key publications
  • Zuidmeer-Jongejan Laurian, Fernández-Rivas Montserrat, Winter Marcel G. T., Akkerdaas Jaap H., Summers Colin, Lebens Ans, Knulst André C., Schilte Piet, Briza Peter, Gadermaier Gabriele, van Ree Ronald Oil body-associated hazelnut allergens including oleosins are underrepresented in diagnostic extracts but associated with severe symptoms Clinical and translational allergy 2014;4 (1):4 [PubMed]
  • Burney P. G. J., Potts J., Kummeling I., Mills E. N. C., Clausen M., Dubakiene R., Barreales L., Fernandez-Perez C., Fernandez-Rivas M., Le T.-M., Knulst A. C., Kowalski M. L., Lidholm J., Ballmer-Weber B. K., Braun-Fahlander C., Mustakov T., Kralimarkova T., Popov T., Sakellariou A., Papadopoulos N. G., Versteeg S. A., Zuidmeer L., Akkerdaas J. H., Hoffmann-Sommergruber K., van Ree R. The prevalence and distribution of food sensitization in European adults Allergy 2014;69 (3):365-371 [PubMed]
  • Amoah Abena S., Obeng Benedicta B., Larbi Irene A., Versteeg Serge A., Aryeetey Yvonne, Akkerdaas Jaap H., Zuidmeer Laurian, Lidholm Jonas, Fernández-Rivas Montserrat, Hartgers Franca C., Boakye Daniel A., van Ree Ronald, Yazdanbakhsh Maria Peanut-specific IgE antibodies in asymptomatic Ghanaian children possibly caused by carbohydrate determinant cross-reactivity Journal of allergy and clinical immunology 2013;132 (3):639-647 [PubMed]
  • Masthoff Laury J. N., Mattsson Lars, Zuidmeer-Jongejan Laurian, Lidholm Jonas, Andersson Kerstin, Akkerdaas Jaap H., Versteeg Serge A., Garino Cristiano, Meijer Yolanda, Kentie Petra, Versluis Astrid, den Hartog Jager Constance F., Bruijnzeel-Koomen Carla A. F. M., Knulst André C., van Ree Ronald, van Hoffen Els, Pasmans Suzanne G. M. A. Sensitization to Cor a 9 and Cor a 14 is highly specific for a hazelnut allergy with objective symptoms in Dutch children and adults Journal of allergy and clinical immunology 2013;132 (2):393-399 [PubMed]
  • Flinterman Annebeth E., Akkerdaas Jaap H., den Hartog Jager Constance F., Rigby Neil M., Fernandez-Rivas Montserrat, Hoekstra Maarten O., Bruijnzeel-Koomen Carla A., Knulst André C., van Ree Ronald, Pasmans Suzanne G. Lipid transfer protein-linked hazelnut allergy in children from a non-Mediterranean birch-endemic area Journal of allergy and clinical immunology 2008;121 (2):423-428.e2 [PubMed]
All Publications
Research programmes

Prof. R. van Ree PhD (Molecular mechanisms of disease induction, symptom expression, immunotherpay and prevention in IgE-mediated allergy)