Prof. dr. J.M. Prins

Main activities
Patient care, Research, Teaching
Infectious Diseases
Focus of research

Optimization of antibiotic treatment:

  • Treatment of community-acquired pneumonia and other respiratory infections
  • Antibiotic Stewardship
  • Quality indicators of antibiotic treatment

Treatment of HIV infection:

  • Primary HIV infection,
  • Adherence
  • Premalignant anal dysplasia
  • Innovative treatment modalities
Key publications
  • Bos JC, van Hest RM, Mistício MC, Nunguiane G, Lang CN, Beirão JC, Mathôt RAA, Prins JM, Pharmacokinetics and Pharmacodynamic Target Attainment of Benzylpenicillin in an Adult Severely Ill Sub-Saharan African Patient Population. CLIN INFECT DIS 2018;66 (8):1261-1269 [PubMed]
  • van Velzen P , ter Riet G, Bresser P, Baars JJ, van den Berg BTJ, van den Berg JWK, Brinkman P, Dagelet JWF, Daniels JMA, Groeneveld-Tjiong DRGL, Jonkers RE, van Kan C, Krouwels FH, Pool K, Rudolphus A, Sterk PJ, Prins JM, Doxycycline for outpatient-treated acute exacerbations of COPD: a randomised double-blind placebo-controlled trial. LANCET RESP MED 2017;5 (6):492-499 [PubMed]
  • de Bruin M, Oberjé EJM, Viechtbauer W, Nobel HE, Hiligsmann M, van Nieuwkoop C, Veenstra J, Pijnappel FJ, Kroon FP, van Zonneveld L, Groeneveld PHP, van Broekhuizen M, Evers SMAA, Prins JM, Effectiveness and cost-effectiveness of a nurse-delivered intervention to improve adherence to treatment for HIV: a pragmatic, multicentre, open-label, randomised clinical trial. LANCET INFECT DIS 2017;17 (6):595-604 [PubMed]
  • Schuts EC, Hulscher MEJL, Mouton JW, Verduin CM, Stuart JWTC, Overdiek HWPM, van der Linden PD, Natsch S, Hertogh CMPM, Wolfs TFW, Schouten JA, Kullberg BJ, Prins JM, Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis. LANCET INFECT DIS 2016;16 (7):847-856 [PubMed]
  • Richel O, de Vries HJC, van Noesel CJM, Dijkgraaf MGW, Prins JM, Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial. LANCET ONCOL 2013;14 (4):346-353-353 [PubMed]
All Publications
Curriculum Vitae

Jan Prins is professor of Infectious Diseases at the University of Amsterdam. He works as Infectious Diseases specialist in the Academic Medical Center (AMC) in Amsterdam, the Netherlands. He is head of the  Department of Internal Medicine at the AMC.

Research programmes

Optimization of Antibiotic Therapy and Treatment of HIV Infection

Theme:  Infection and Immunity

Prof. dr. J.M. Prins
Prof. dr. S.E. Geerlings
Dr. J.T.M. van der Meer
Dr. F.J.B. Nellen

PhD Students
I.A.H. van den Berk
A.K. van den Broek
M. Dijkstra
Drs. K.C.M. Gosens MD
M.C. Kallen
M.M.N.P. Kanglie MD
J.E. Oryszczyn
E.C. Schuts BSc
P. van Velzen MD (Infectious Diseases (with prof JM Prins))
R.P. van der Zee MD MSc
Drs. T.W. van der Vaart (Universiteit van Utrecht)

Other research related activities
  • Board of directors / Trustees / Supervisory board, Dutch Working Party on antibiotic Policy (SWAB)
  • Contribution to guidelines and protocols, CBO - Meningitis
  • Contribution to guidelines and protocols, NVAB (Dutch Association of HIV Physicians)
  • Contribution to guidelines and protocols, NHG - Acuut Hoesten
  • Membership of advisory board / Consultant, CVZ (College voor Zorgverzekeringen, Netherlands Health Insurance Board)
  • Membership of advisory board / Consultant, ZonMw (Netherlands Organisation for Health Research and Development)
  • Membership of advisory board / Consultant, Stichting de Merel
Current research funding
  • AMC
  • AMC (Vrijgesteld)
  • EC
  • GlaxoSmithKline BV
  • GlaxoSmithKline Research & Development Ltd.
  • Innovatiefonds Zorgverzekeraars
  • Janssen Cilag B.V.
  • KWF Kankerbestrijding
  • St. Werkgroep Antibioticabeleid (SWAB)
  • ZonMw