Prof. dr. J.T. Annema

Main activities
Patient care, Research, Teaching
Pulmonary Endoscopy
Focus of research

Developement of novel Endoscopic Diagnostic and treatment strategies for pulmonary diseases

  • Endosonography for lung and mediastinal diseases (lungcancer/ sarcoidosis)
  • Pulmonary interventions for obstructive ( bronchial thermoplasty/ endoscopic lung volume reduction) and interstitial lung diseases
  • Evaluation of innovative imaging (OCT and CLE) in lung diseases
Key publications
  • von Bartheld MB, Dekkers OM, Szlubowski A, Eberhardt R, Herth FJ, in 't Veen JCCM, de Jong YP, van der Heijden EHFM, Tournoy KG, Claussen M, van den Blink B, Shah PL, Zoumot Z, Clementsen P, Porsbjerg C, Mauad T, Bernardi FD, van Zwet EW, Rabe KF, Annema JT, Endosonography vs conventional bronchoscopy for the diagnosis of sarcoidosis: the GRANULOMA randomized clinical trial. JAMA-J AM MED ASSOC 2013;309 (23):2457-2464 [PubMed]
  • Tournoy KG, Keller SM, Annema JT, Mediastinal staging of lung cancer: novel concepts. LANCET ONCOL 2012;13 (5):E221-E229 [PubMed]
  • Korevaar DA, Crombag LM, Cohen JF, Spijker R, Bossuyt PM, Annema JT, Added value of combined endobronchial and oesophageal endosonography for mediastinal nodal staging in lung cancer: a systematic review and meta-analysis. LANCET RESP MED 2016;4 (12):960-968 [PubMed]
  • Kuijvenhoven JC, Korevaar DA, Tournoy KG, Malfait TLA, Dooms C, Rintoul RC, Annema JT, Five-Year Survival After Endosonography vs Mediastinoscopy for Mediastinal Nodal Staging of Lung Cancer. JAMA-J AM MED ASSOC 2016;316 (10):1110-1112 [PubMed]
  • Vilmann P, Clementsen PF, Colella S, Siemsen M, de Leyn P, Dumonceau JM, Herth FJ, Larghi A, Vazquez-Sequeiros E, Hassan C, Crombag L, Korevaar DA, Konge L, Annema JT, Combined endobronchial and oesophageal endosonography for the diagnosis and staging of lung cancer. European Society of Gastrointestinal Endoscopy (ESGE) Guideline, in cooperation with the European Respiratory Society (ERS) and the European Society of Thoracic Surgeons (ESTS). EUR RESPIR J 2015;46 (1):40-60 [PubMed]
All Publications
Research programmes

Pulmonary Endoscopy

The development of novel diagnostic and therapeutic endoscopic approaches

for the diagnosing and staging of lung cancer, the assesment of sarcoidosis and longfibrosis, treatment of severe asthma and COPD


using the following tools

endosonography, innovative imaging (OCT/ CLE), therapeutic options like cryo, thermoplasty, targeted lung denervations and endobronchial valves.


Prof. dr. J.T. Annema
Dr. P.I. Bonta MD PhD

Dr. M.A. van de Pol

PhD Students
J.E. Bousema
A.W.M. Goorsenberg
Drs. J.C. Kuijvenhoven
L. Wijmans
Drs. K. Mooij - Kalverda

Other research related activities
  • Membership of medical or scientific committee, European Respiratory Society, Chair of Interventional Pulmonology
  • Membership of medical or scientific committee, NVALT Nederlandse Vereniging voor Artsen Longziketen en Tuberculose, Voorzitter Sectie Pulmonale Intreventies
  • Membership of medical or scientific committee, Order of Medical Specialists, Commisie cursorisch onderwijs
Current research funding
  • AMC
  • Boston Scientific Corporation
  • Cook Medical Ireland Ltd.
  • Holaira, Inc.
  • Longfonds
  • Mauna Kea Technologies
  • N.K.I.
  • ZonMw