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Prof. dr. M.G.H. Besselink MD MSc PhD

Position
Other
Main activities
Patient care, Research
Specialisation
Hepato-Pancreato-Biliary surgery
Focus of research
Pancreatic and Hepatobiliary (HPB) surgery
  1. Minimally invasive pancreas and liver surgery
  2. Dutch Pancreatic Cancer Group: optimizing outcomes of pancreatic surgery
  3. Dutch Pancreas Biobank: translational research pancreatic and peri-ampullary cancer
  4. Dutch Pancreatitis Study Group: improving clinical treatment of acute and chronic pancreatitis

 

Key publications
  • de Rooij T, Klompmaker S, Abu Hilal M, Kendrick ML, Busch OR, Besselink MG, Laparoscopic pancreatic surgery for benign and malignant disease. NAT REV GASTRO HEPAT 2016;13 (4):227-238 [PubMed]
  • de Rooij T, Lu MZ, Steen MW, Gerhards MF, Dijkgraaf MG, Busch OR, Lips DJ, Festen S, Besselink MG, Minimally Invasive Versus Open Pancreatoduodenectomy: Systematic Review and Meta-analysis of Comparative Cohort and Registry Studies. ANN SURG 2016;264 (2):257-267 [PubMed]
  • de Rooij T, Jilesen AP, Boerma D, Bonsing BA, Bosscha K, van Dam RM, van Dieren S, Dijkgraaf MG, van Eijck CH, Gerhards MF, van Goor H, van der Harst E, de Hingh IH, Kazemier G, Klaase JM, Molenaar IQ, Nieveen van Dijkum EJ, Patijn GA, van Santvoort HC, Scheepers JJ, van der Schelling GP, Sieders E, Vogel JA, Busch OR, Besselink MG, A nationwide comparison of laparoscopic and open distal pancreatectomy for benign and malignant disease. J AM COLL SURGEONS 2015;220 (3):263-270.e1 [PubMed]
  • Ahmed Ali U, van der Sluis PC, Issa Y, Habaga IA, Gooszen HG, Flum DR, Algra A, Besselink MG, Trends in Worldwide Volume and Methodological Quality of Surgical Randomized Controlled Trials. ANN SURG 2013;258 (2):199-207 [PubMed]
All Publications
Curriculum Vitae

Training:

  • 2013 (sept-), HPB surgeon, AMC Amsterdam
  • 2013 (jan-aug), Fellow Laparoscopic HPB surgery, University Hospital Southampton
  • 2012, Fellow Hepato-Pancreato-Biliary (HPB) surgery, AMC Amsterdam
  • 2005-2011, Training gastrointestinal and oncological surgery, UMC Utrecht and St.Antonius Nieuwegein

Positions National

  • 2014 Oncology Committee - Netherlands Federation UMCs (NFU)
  • 2013 Scientific committee Dutch Hepato Biliary Audit (DHBA)
  • 2013 Chair scientific committee Dutch Pancreatic Cancer Audit (DPCA)
  • 2012 Co-founder and board Dutch Pancreatic Cancer Group (DPCG; www.pancreaskanker.nl)
  • 2011 Initiator and co-founder Dutch Pancreatic Biobank (www.pancreasparel.nl)
  • 2002 Co-founder and board Dutch Pancreatitis Study Group (DPSG; www.pancreatitis.nl)

Positions International

  • 2015 Steering Committee, European guideline pancreatic cysts (EPC, EAHPBA, ESGE)
  • 2015 Steering Committee, European consensus minimally invasive pancreatic surgery (EAES)
  • 2015 Steering Committee, International consensus minimally invasive pancreatic resection (IHPBA)
  • 2015 Steering Committee, Consensus locally advanced pancreatic cancer, American Hepato-Pancreato-Biliary Association (AHPBA)
  • 2014 Steering Comittee, European guidelines chronic pancreatitis HaPanEU, United European Gastroenterology (UEG)
  • 2014 Scientific Advisory Committee, Pancreatic Cancer Action UK
  • 2014 Ethicon European Center of Excellence for laparoscopic pancreatic surgery
  • 2014 Scientific Advisory Board, Int. Association Pancreatology (IAP)
  • 2013 Coordinator IAP/APA evidence-based guidelines acute pancreatitis
  • 2013 Expert Panel Euro Pancreatic Cancer Index 2013
  • 2013 Education and Training Committee, Int. HPB Association (IHPBA)
  • 2013 Scientific Committee, European-African HPB Association (E-AHPBA)

Clinical 

  • Surgery for pancreatic cancer ("alvleesklierkanker") and IPMN/cysts,  Whipple/PPPD
  • Laparoscopic pancreatic surgery; incl laparoscopic Whipple, laparoscopic distal pancreatectomy 
  • Laparoscopic liver surgery; incl laparoscopic hemi-hepatectomy
  • Ablation for locally non-resectable pancreatic cancer with irreversible electroporation (Nanoknife) and radiofrequency ablation (RFA)
  • Surgery for acute and chronic pancreatitis 

Awards

  • 2011 Rising Star Award, Association of National European and Mediterranean Societies of Gastroenterology
  • 2010 Nominee for “Zorgveiligprijs” (safe care price), Dutch Healthcare Inspectorate (IGZ) for the project “Nationwide Online Expertpanel”
  • 2009 AstraZeneca Gastrointestinal Research Award, Dutch Gastroenterological Association (NVGE), for best gastroenterological PhD thesis in 2008
  • 2009 Schoemaker Award, The Association of Surgeons of the Netherlands for best surgical PhD-thesis in 2008

 

Research programmes

Pancreatic and Hepato-Biliary Surgery

Pancreatic and Hepatobiliary (HPB) surgery

  1. Minimally invasive pancreas and liver surgery, ablation
  2. Dutch Pancreatic Cancer Audit: optimizing outcomes of pancreatic surgery
  3. Dutch Pancreas Biobank: translational research pancreatic and peri-ampullary cancer
  4. Dutch Pancreatitis Study Group: improving clinical treatment of acute and chronic pancreatiti

Ad 1: This includes laparoscopic pancreatic surgery (Nationwide LEOPARD-1 and -2 trials), laparoscopic liver surgery (Nationwide LAELIVE project) and treatment of locally irresectable pancreatic cancer with induction chemotherapy and ablation strategies for locally advanced pancreatic cancer and biliary cancer (IMPALA project: irreversible electroporation and Nationwide PELICAN trial: radiofrequency ablation). The group involves pancreatic surgeons, interventional radiologists, gastroenterologists, medical oncologists, radiologists, pathologists and 6 PhD students.

Ad 2-3: Marc Besselink co-founded the Dutch Pancreatic Cancer Group (DPCG), is the chair of the scientific committee and the manager of the Dutch Pancreatic Biobank (PancreasParel). The DPCG consists of 90 medical specialists, 8 PhD students and nurses involved with the care for pancreatic cancer in 17 Dutch hospitals, including all university medical centers.

Ad 4: Marc Besselink co-founded the Dutch Pancreatitis Study Group (DPSG) of which the first 5 randomized controlled trials were all published in the top 3 general-medical journals.PROPATRIA-Lancet 2008, PANTER-New Engl J Med 2010, PENGUIN-JAMA 2012, PYTHON-New Engl J Med 2014. PONCHO-Lancet 2016. The DPSG consisting of 120+ medical specialists, 6 PhD students and 2 nurses involved with the care for pancreatitis patients in 25 Dutch hospitals including all university medical centers. Current projects (2017) include the POINTER trial.

 

Faculty
Prof. dr. M.G.H. Besselink MD MSc PhD
Prof. dr. O.R.C. Busch
Dr. J.E. van Hooft MD MSc PhD
Prof. dr. H.W.M. van Laarhoven
K.P. van Lienden MD
Dr. H. Wilmink

Postdocs
Dr. H.C. van Santvoort MD PhD

PhD Students
Ir. P. Agnass
S.M. van Dijk
A. Furumaya
B. Gorgec
C.M. Heidsma
N. van der Heijde
N.C.M. van Huijgevoort
M. Korrel BSc
A.E.J. Latenstein MD
S. Lof
T.M. Mackay
A.L. Moekotte
T.H. Mungroop MD MSc
M.J. van der Poel
M.A. Pool
Drs. S. van Roessel MD
Drs. A.M. Schreuder MD
M.W. Steen
M. Strijker
D.S. Umans
E. van Veldhuisen BSc
Drs. F.L.I.M. Vissers
J.A. Vogel
M.J.W. Zwart
D. Da Costa MD (St.Antonius Nieuwegein)
N.J. Schepers MD (Erasmus Medical Center Rotterdam)
M.A. Walma MD (University Medical Center Utrecht)

Others
T. de Rooij BSc

Other research related activities
  • Contribution to guidelines and protocols, International Ass. Pancreatology/ American Ass. Pancreatology Evidence-based guidelines on acute pancreatitis
  • Contribution to guidelines and protocols, European evidence-based guideline pancreatic cystic neoplasms
  • Contribution to guidelines and protocols, European evidence-based guideline chronic panreatitis
  • Board of directors / Trustees / Supervisory board, Dutch Pancreatic Cancer Group
  • Board of directors / Trustees / Supervisory board, Dutch Pancreatitis Study Group
  • Membership of advisory board / Consultant, Pancreatic Cancer Action UK
  • Membership of advisory board / Consultant, Alvleeskliervereniging
  • Membership of advisory board / Consultant, Lisa Waller Hayes Foundation for pancreatic cancer
  • Membership of editorial board / Editorship, ANNALS OF SURGERY
  • Membership of editorial board / Editorship, BRITISH JOURNAL OF SURGERY
  • Membership of editorial board / Editorship, HPB SURGERY
  • Membership of editorial board / Editorship, PANCREATOLOGY
  • Membership of editorial board / Editorship, JOURNAL OF GASTROINTESTINAL SURGERY
Current research funding
  • Allergan Pharmaceuticals International Ltd
  • AMC (Vrijgesteld)
  • Celgene International Il Sàrl
  • Covidien AG
  • Fonds NUTS-OHRA
  • Johnson & Johnson Medical BV
  • Johnson & Johnson Medical Ltd.
  • KWF Kankerbestrijding
  • Maag, Lever, Darm Stichting
  • Mylan Healthcare B.V.
  • NIEUWE DEB IND
  • Olympus Winter & Ibe
  • Stichting Nationaal Fonds tegen kanker
  • UEG United European Gastroenterology
  • UMCG
  • UMC Groningen
  • Zealand Pharma A/S